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A Biobank of Breast Cancer Explants with Preserved Intra-tumor Heterogeneity to Screen Anticancer Compounds

artículo científico publicado en 2016

A large collection of integrated genomically characterized patient-derived xenografts highlighting the heterogeneity of triple-negative breast cancer

artículo científico publicado en 2019

A preclinical therapeutic schedule optimizing docetaxel plus estramustine administration in prostate cancer.

artículo científico publicado en 2010

A short-term colorectal cancer sphere culture as a relevant tool for human cancer biology investigation.

artículo científico publicado en 2013

AKT Antagonist AZD5363 Influences Estrogen Receptor Function in Endocrine-Resistant Breast Cancer and Synergizes with Fulvestrant (ICI182780) In Vivo.

artículo científico publicado en 2015

Acquired resistance to endocrine treatments is associated with tumor-specific molecular changes in patient-derived luminal breast cancer xenografts.

artículo científico publicado en 2014

Activation of IFN/STAT1 signalling predicts response to chemotherapy in oestrogen receptor-negative breast cancer

artículo científico publicado en 2015

BRCAness, SLFN11, and RB1 loss predict response to topoisomerase I inhibitors in triple-negative breast cancers

artículo científico publicado en 2020

Biopathological Significance of TLR9 Expression in Cancer Cells and Tumor Microenvironment Across Invasive Breast Carcinomas Subtypes.

artículo científico publicado en 2016

CXCR4 inhibitors could benefit to HER2 but not to triple-negative breast cancer patients

artículo científico publicado en 2016

Can diaphragmatic ultrasonography performed during the T-tube trial predict weaning failure? The role of diaphragmatic rapid shallow breathing index.

artículo científico publicado en 2016

Capecitabine efficacy is correlated with TYMP and RB expression in PDX established from triple-negative breast cancers.

artículo científico publicado en 2018

Clinical value of R-spondins in triple-negative and metaplastic breast cancers

artículo científico publicado en 2017

Combination of COX-2 expression and PIK3CA mutation as prognostic and predictive markers for celecoxib treatment in breast cancer.

artículo científico publicado en 2016

Conservation of copy number profiles during engraftment and passaging of patient-derived cancer xenografts

scientific article published on 07 January 2021

Cytidine Deaminase Deficiency Reveals New Therapeutic Opportunities against Cancer

artículo científico publicado en 2016

Expression of MT4-MMP, EGFR, and RB in Triple-Negative Breast Cancer Strongly Sensitizes Tumors to Erlotinib and Palbociclib Combination Therapy

scientific article published on 30 November 2018

Focus on renal blood flow in mechanically ventilated patients with SARS-CoV-2: a prospective pilot study

artículo científico publicado en 2021

HDAC inhibition does not induce estrogen receptor in human triple-negative breast cancer cell lines and patient-derived xenografts.

artículo científico publicado en 2014

Heterogeneity of regional inflection points from pressure-volume curves assessed by electrical impedance tomography

artículo científico publicado en 2019

High-throughput single-cell ChIP-seq identifies heterogeneity of chromatin states in breast cancer

scientific article published on 31 May 2019

Impaired PRC2 activity promotes transcriptional instability and favors breast tumorigenesis

artículo científico publicado en 2015

Improving breast cancer sensitivity to paclitaxel by increasing aneuploidy

scientific article published on 04 November 2019

Inhibition of mTOR downregulates expression of DNA repair proteins and is highly efficient against BRCA2-mutated breast cancer in combination to PARP inhibition

artículo científico publicado en 2018

Interrogating open issues in cancer medicine with patient-derived xenografts

artículo científico publicado en 2017

Interrogating open issues in cancer precision medicine with patient-derived xenografts.

artículo científico publicado en 2017

Mechanisms of Therapy Resistance in Patient-Derived Xenograft Models of BRCA1-Deficient Breast Cancer

artículo científico publicado en 2016

Medullary Breast Carcinoma, a Triple-Negative Breast Cancer Associated with BCLG Overexpression

artículo científico publicado en 2018

Metabolic Response to Everolimus in Patient-Derived Triple-Negative Breast Cancer Xenografts.

artículo científico publicado en 2017

Modeling of response to endocrine therapy in a panel of human luminal breast cancer xenografts

scientific article published on 16 October 2011

Newly characterised ex vivo colospheres as a three-dimensional colon cancer cell model of tumour aggressiveness.

artículo científico publicado en 2009

Oestrogen Non-Genomic Signalling is Activated in Tamoxifen-Resistant Breast Cancer

scientific article published on 05 June 2019

PARP Inhibition Increases the Response to Chemotherapy in Uveal Melanoma

artículo científico publicado en 2019

PKD1 is a potential biomarker and therapeutic target in triple-negative breast cancer.

artículo científico publicado en 2018

PLK1 inhibition exhibits strong anti-tumoral activity in CCND1-driven breast cancer metastases with acquired palbociclib resistance

scientific article published on 13 August 2020

Patient-derived tumour xenografts as models for breast cancer drug development

artículo científico publicado en 2014

Patient-derived xenograft (PDX) models in basic and translational breast cancer research.

artículo científico publicado en 2016

Patterns of HER2 Gene Amplification and Response to Anti-HER2 Therapies

artículo científico publicado en 2015

Personalized Positive End-Expiratory Pressure in Acute Respiratory Distress Syndrome: Comparison Between Optimal Distribution of Regional Ventilation and Positive Transpulmonary Pressure

scientific article published on 16 June 2020

Protein arginine methyltransferase 5: A novel therapeutic target for triple-negative breast cancers.

artículo científico publicado en 2019

Reprogramming of Amino Acid Transporters to Support Aspartate and Glutamate Dependency Sustains Endocrine Resistance in Breast Cancer

scientific article published on 01 July 2019

Targeting mTOR pathway inhibits tumor growth in different molecular subtypes of triple-negative breast cancers.

scientific article published on 21 June 2016

The arginine methyltransferase PRMT1 regulates IGF-1 signaling in breast cancer

artículo científico publicado en 2019

The iron chelator deferasirox synergises with chemotherapy to treat triple-negative breast cancers

artículo científico publicado en 2018

The molecular mechanisms underlying the ERα-36-mediated signaling in breast cancer

artículo científico publicado en 2016

Tinengotinib (TT-00420), a Novel Spectrum-Selective Small-Molecule Kinase Inhibitor, Is Highly Active Against Triple-Negative Breast Cancer

scientific article published in 2022

Tyrphostin AG 1024 modulates radiosensitivity in human breast cancer cells

artículo científico publicado el 14 de diciembre de 2001

Vandetanib as a potential new treatment for estrogen receptor-negative breast cancers.

artículo científico publicado en 2016