Lista de obras -

A genome-wide screen for genetic variants that modify the recruitment of REST to its target genes

artículo científico publicado en 2012

A unique Oct4 interface is crucial for reprogramming to pluripotency

artículo científico publicado en 2013

Assessment of CASP7 structure predictions for template free targets

artículo científico publicado en 2007

Cancer-associated missense mutations enhance the pluripotency reprogramming activity of OCT4 and SOX17

scientific article published on 17 October 2019

Capturing the interactome of newly transcribed RNA.

artículo científico publicado en 2018

Cell fate reprogramming through engineering of native transcription factors

artículo científico publicado en 2018

Changing POU dimerization preferences converts Oct6 into a pluripotency inducer

artículo científico publicado en 2016

Co-motif discovery identifies an Esrrb-Sox2-DNA ternary complex as a mediator of transcriptional differences between mouse embryonic and epiblast stem cells

scientific journal article

Comprehensive prediction in 78 human cell lines reveals rigidity and compactness of transcription factor dimers

artículo científico publicado en 2013

Conversion of Sox17 into a pluripotency reprogramming factor by reengineering its association with Oct4 on DNA

artículo científico publicado en 2011

Coop-Seq Analysis Demonstrates that Sox2 Evokes Latent Specificities in the DNA Recognition by Pax6.

artículo científico publicado en 2017

Crystal structure and DNA binding of the homeodomain of the stem cell transcription factor Nanog

artículo científico publicado en 2008

Crystal structure of the dimeric Oct6 (POU3f1) POU domain bound to palindromic MORE DNA

artículo científico publicado en 2011

Crystallization and preliminary X-ray diffraction analysis of the Pax9 paired domain bound to a DC5 enhancer DNA element.

artículo científico publicado en 2014

DNA-mediated cooperativity facilitates the co-selection of cryptic enhancer sequences by SOX2 and PAX6 transcription factors.

artículo científico publicado en 2015

DNA-mediated dimerization on a compact sequence signature controls enhancer engagement and regulation by FOXA1.

artículo científico publicado en 2018

Directed Evolution of Reprogramming Factors by Cell Selection and Sequencing

artículo científico publicado en 2018

Dissecting the role of distinct OCT4-SOX2 heterodimer configurations in pluripotency.

artículo científico publicado en 2015

Diversity among POU transcription factors in chromatin recognition and cell fate reprogramming.

artículo científico publicado en 2018

Evolution of the vertebrate gene regulatory network controlled by the transcriptional repressor REST. ⬇️

artículo científico publicado en 2009

Exploring the utility of organo-polyoxometalate hybrids to inhibit SOX transcription factors

artículo científico publicado en 2014

Identification of a Polyoxometalate Inhibitor of the DNA Binding Activity of Sox2

artículo científico publicado en 2011

Identification of a Wells-Dawson polyoxometalate-based AP-2γ inhibitor with pro-apoptotic activity

scientific article published on 11 June 2018

JMJD3 acts in tandem with KLF4 to facilitate reprogramming to pluripotency

artículo científico publicado en 2020

Linc-YY1 promotes myogenic differentiation and muscle regeneration through an interaction with the transcription factor YY1.

artículo científico publicado en 2015

LncRNA Dum interacts with Dnmts to regulate Dppa2 expression during myogenic differentiation and muscle regeneration

scientific journal article

Molecular basis for the genome engagement by Sox proteins

artículo científico publicado en 2016

Mutations involving the SRY-related gene SOX8 are associated with a spectrum of human reproductive anomalies.

artículo científico publicado en 2018

OCT4: A penetrant pluripotency inducer.

artículo científico publicado en 2014

Oct4 switches partnering from Sox2 to Sox17 to reinterpret the enhancer code and specify endoderm

artículo científico publicado en 2013

Pathogenic variants in the DEAH-box RNA helicase DHX37 are a frequent cause of 46,XY gonadal dysgenesis and 46,XY testicular regression syndrome

artículo científico publicado en 2019

Pharmacological targeting of the transcription factor SOX18 delays breast cancer in mice.

artículo científico publicado en 2017

Pluripotency reprogramming by competent and incompetent POU factors uncovers temporal dependency for Oct4 and Sox2

artículo científico publicado en 2019

Quantitative profiling of selective Sox/POU pairing on hundreds of sequences in parallel by Coop-seq.

artículo científico publicado en 2016

Rational Structure-Based Design of Bright GFP-Based Complexes with Tunable Dimerization

artículo científico publicado en 2015

Reprogramming cells with synthetic proteins

artículo científico publicado en 2015

SOX17 in cellular reprogramming and cancer

scientific article published on 13 August 2019

SOX9 and SOX10 control fluid homeostasis in the inner ear for hearing through independent and cooperative mechanisms

scientific article published in 2022

SOXE neofunctionalization and elaboration of the neural crest during chordate evolution.

artículo científico publicado en 2016

SOXE transcription factors form selective dimers on non-compact DNA motifs through multifaceted interactions between dimerization and high-mobility group domains

artículo científico publicado en 2015

Scientists and societies. Horizons in molecular biology

artículo científico publicado en 2005

Small-Molecule Inhibitors of the SOX18 Transcription Factor.

artículo científico publicado en 2017

Structural basis for the SOX-dependent genomic redistribution of OCT4 in stem cell differentiation.

artículo científico publicado en 2014

Structural basis for the cooperative DNA recognition by Smad4 MH1 dimers

scientific journal article

Structure and decoy-mediated inhibition of the SOX18/Prox1-DNA interaction

artículo científico publicado en 2016

Structure of Smad1 MH1/DNA complex reveals distinctive rearrangements of BMP and TGF- effectors

artículo científico publicado en 2010

Structures of Escherichia coli NAD synthetase with substrates and products reveal mechanistic rearrangements.

artículo científico publicado en 2005

Synergistic co-regulation and competition by a SOX9-GLI-FOXA phasic transcriptional network coordinate chondrocyte differentiation transitions.

artículo científico publicado en 2018

The Crystal Structure of a Maxi/Mini-Ferritin Chimera Reveals Guiding Principles for the Assembly of Protein Cages.

artículo científico publicado en 2017

The crystal structure of the Sox4 HMG domain–DNA complex suggests a mechanism for positional interdependence in DNA recognition ⬇️

artículo científico publicado el 1 de abril de 2012

The structure of Sox17 bound to DNA reveals a conserved bending topology but selective protein interaction platforms

artículo científico publicado en 2009

TherMos: Estimating protein-DNA binding energies from in vivo binding profiles

artículo científico publicado en 2013

What makes a pluripotency reprogramming factor?

artículo científico

glbase: a framework for combining, analyzing and displaying heterogeneous genomic and high-throughput sequencing data

artículo científico publicado en 2014

Lista de obras de

A genome-wide screen for genetic variants that modify the recruitment of REST to its target genes

A unique Oct4 interface is crucial for reprogramming to pluripotency

Assessment of CASP7 structure predictions for template free targets

Cancer-associated missense mutations enhance the pluripotency reprogramming activity of OCT4 and SOX17

Capturing the interactome of newly transcribed RNA.

Cell fate reprogramming through engineering of native transcription factors

Changing POU dimerization preferences converts Oct6 into a pluripotency inducer

Co-motif discovery identifies an Esrrb-Sox2-DNA ternary complex as a mediator of transcriptional differences between mouse embryonic and epiblast stem cells

Comprehensive prediction in 78 human cell lines reveals rigidity and compactness of transcription factor dimers

Conversion of Sox17 into a pluripotency reprogramming factor by reengineering its association with Oct4 on DNA

Coop-Seq Analysis Demonstrates that Sox2 Evokes Latent Specificities in the DNA Recognition by Pax6.

Crystal structure and DNA binding of the homeodomain of the stem cell transcription factor Nanog

Crystal structure of the dimeric Oct6 (POU3f1) POU domain bound to palindromic MORE DNA

Crystallization and preliminary X-ray diffraction analysis of the Pax9 paired domain bound to a DC5 enhancer DNA element.

DNA-mediated cooperativity facilitates the co-selection of cryptic enhancer sequences by SOX2 and PAX6 transcription factors.

DNA-mediated dimerization on a compact sequence signature controls enhancer engagement and regulation by FOXA1.

Directed Evolution of Reprogramming Factors by Cell Selection and Sequencing

Dissecting the role of distinct OCT4-SOX2 heterodimer configurations in pluripotency.

Diversity among POU transcription factors in chromatin recognition and cell fate reprogramming.

Evolution of the vertebrate gene regulatory network controlled by the transcriptional repressor REST. ⬇️

Exploring the utility of organo-polyoxometalate hybrids to inhibit SOX transcription factors

Identification of a Polyoxometalate Inhibitor of the DNA Binding Activity of Sox2

Identification of a Wells-Dawson polyoxometalate-based AP-2γ inhibitor with pro-apoptotic activity

JMJD3 acts in tandem with KLF4 to facilitate reprogramming to pluripotency

Linc-YY1 promotes myogenic differentiation and muscle regeneration through an interaction with the transcription factor YY1.

LncRNA Dum interacts with Dnmts to regulate Dppa2 expression during myogenic differentiation and muscle regeneration

Molecular basis for the genome engagement by Sox proteins

Mutations involving the SRY-related gene SOX8 are associated with a spectrum of human reproductive anomalies.

OCT4: A penetrant pluripotency inducer.

Oct4 switches partnering from Sox2 to Sox17 to reinterpret the enhancer code and specify endoderm

Pathogenic variants in the DEAH-box RNA helicase DHX37 are a frequent cause of 46,XY gonadal dysgenesis and 46,XY testicular regression syndrome

Pharmacological targeting of the transcription factor SOX18 delays breast cancer in mice.

Pluripotency reprogramming by competent and incompetent POU factors uncovers temporal dependency for Oct4 and Sox2

Quantitative profiling of selective Sox/POU pairing on hundreds of sequences in parallel by Coop-seq.

Rational Structure-Based Design of Bright GFP-Based Complexes with Tunable Dimerization

Reprogramming cells with synthetic proteins

SOX17 in cellular reprogramming and cancer

SOX9 and SOX10 control fluid homeostasis in the inner ear for hearing through independent and cooperative mechanisms

SOXE neofunctionalization and elaboration of the neural crest during chordate evolution.

SOXE transcription factors form selective dimers on non-compact DNA motifs through multifaceted interactions between dimerization and high-mobility group domains

Scientists and societies. Horizons in molecular biology

Small-Molecule Inhibitors of the SOX18 Transcription Factor.

Structural basis for the SOX-dependent genomic redistribution of OCT4 in stem cell differentiation.

Structural basis for the cooperative DNA recognition by Smad4 MH1 dimers

Structure and decoy-mediated inhibition of the SOX18/Prox1-DNA interaction

Structure of Smad1 MH1/DNA complex reveals distinctive rearrangements of BMP and TGF- effectors

Structures of Escherichia coli NAD synthetase with substrates and products reveal mechanistic rearrangements.

Synergistic co-regulation and competition by a SOX9-GLI-FOXA phasic transcriptional network coordinate chondrocyte differentiation transitions.

The Crystal Structure of a Maxi/Mini-Ferritin Chimera Reveals Guiding Principles for the Assembly of Protein Cages.

The crystal structure of the Sox4 HMG domain–DNA complex suggests a mechanism for positional interdependence in DNA recognition ⬇️

The structure of Sox17 bound to DNA reveals a conserved bending topology but selective protein interaction platforms

TherMos: Estimating protein-DNA binding energies from in vivo binding profiles

What makes a pluripotency reprogramming factor?

glbase: a framework for combining, analyzing and displaying heterogeneous genomic and high-throughput sequencing data