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A rare heterozygous TREM2 coding variant identified in familial clustering of dementia affects an intrinsically disordered protein region and function of TREM2

scientific article published on 15 September 2019

Adult-to-embryo chemical signaling in the regulation of larval development in trochophore animals: cellular and molecular mechanisms.

artículo científico publicado en 2008

Deficiency of sphingosine-1-phosphate lyase impairs lysosomal metabolism of the amyloid precursor protein

artículo científico publicado en 2014

Functional Relevance of a Novel SlyX Motif in Non-conventional Secretion of Insulin-degrading Enzyme

artículo científico publicado el 16 de mayo de 2011

Functional involvement of γ-secretase in signaling of the triggering receptor expressed on myeloid cells-2 (TREM2).

artículo científico publicado en 2016

Interplay between phosphorylation and palmitoylation mediates plasma membrane targeting and sorting of GAP43.

artículo científico publicado en 2014

Lithium Decreases Glial Fibrillary Acidic Protein in a Mouse Model of Alexander Disease

artículo científico publicado en 2015

Localization of the mouse 5-hydroxytryptamine(1A) receptor in lipid microdomains depends on its palmitoylation and is involved in receptor-mediated signaling.

artículo científico publicado en 2007

Mechanisms underlying dual effects of serotonin during development of Helisoma trivolvis (Mollusca)

artículo científico publicado en 2014

Sequential proteolytic processing of the triggering receptor expressed on myeloid cells-2 (TREM2) protein by ectodomain shedding and γ-secretase-dependent intramembranous cleavage

artículo científico publicado en 2013

Serotonin stimulates secretion of exosomes from microglia cells

artículo científico publicado en 2014

Sphingosine 1-phosphate lyase ablation disrupts presynaptic architecture and function via an ubiquitin- proteasome mediated mechanism.

artículo científico publicado en 2016

Statins in unconventional secretion of insulin-degrading enzyme and degradation of the amyloid-β peptide

artículo científico publicado en 2011

The intact Kunitz domain protects the amyloid precursor protein from being processed by matriptase-2.

artículo científico publicado en 2016

Wnt proteins contribute to neuromuscular junction formation through distinct signaling pathways

artículo científico publicado en 2017

γ-Secretase in microglia - implications for neurodegeneration and neuroinflammation.

artículo científico publicado en 2017