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A novel adeno-associated virus capsid with enhanced neurotropism corrects a lysosomal transmembrane enzyme deficiency.

artículo científico publicado en 2018

AAV9 intracerebroventricular gene therapy improves lifespan, locomotor function and pathology in a mouse model of Niemann-Pick type C1 disease

article

Adeno-associated virus Rep proteins antagonize phosphatase PP1 to counteract KAP1 repression of the latent viral genome.

artículo científico publicado en 2018

Adeno-associated virus Rep represses the human integration site promoter by two pathways that are similar to those required for the regulation of the viral p5 promoter.

artículo científico publicado en 2014

An Improved Adeno-Associated Virus Vector for Neurological Correction of the Mouse Model of Mucopolysaccharidosis IIIA

scientific article published on 04 June 2019

Brief report: self-organizing neuroepithelium from human pluripotent stem cells facilitates derivation of photoreceptors.

artículo científico publicado en 2013

Characterization of the mouse adeno-associated virus AAVS1 ortholog.

artículo científico publicado en 2004

Comparative next-generation sequencing of adeno-associated virus inverted terminal repeats.

artículo científico publicado en 2014

Exchange of functional domains between a bacterial conjugative relaxase and the integrase of the human adeno-associated virus

artículo científico publicado en 2018

Generation of light-producing somatic-transgenic mice using adeno-associated virus vectors

artículo científico publicado en 2020

Herpes Simplex Virus 1 Coinfection Modifies Adeno-associated Virus Genome End Recombination

scientific article published on 10 June 2021

Identification of a Functionally Relevant Adeno-Associated Virus Rep68 Oligomeric Interface

artículo científico publicado en 2016

Inhibition of somatosensory mechanotransduction by annexin A6

scientific article published on 19 June 2018

Presence of a trs-Like Motif Promotes Rep-Mediated Wild-Type Adeno-Associated Virus Type 2 Integration.

artículo científico publicado en 2015

Quantification of AAV particle titers by infrared fluorescence scanning of coomassie-stained sodium dodecyl sulfate-polyacrylamide gels.

artículo científico publicado en 2012

Site-specific integration of adeno-associated virus involves partial duplication of the target locus.

artículo científico publicado en 2009

Structural Studies of AAV2 Rep68 Reveal a Partially Structured Linker and Compact Domain Conformation

artículo científico publicado en 2015

Vector-mediated l-3,4-dihydroxyphenylalanine delivery reverses motor impairments in a primate model of Parkinson's disease

scientific article published on 01 August 2019