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A bioreactor system for the manufacture of a genetically modified Plasmodium falciparum blood stage malaria cell bank for use in a clinical trial

scholarly article published by Alan Frederick Cowman in 2018

Acquisition of antibodies against Plasmodium falciparum merozoites and malaria immunity in young children and the influence of age, force of infection, and magnitude of response

artículo científico publicado en 2014

Anaemia in hospitalised preschool children from a rural area in Mozambique: a case control study in search for aetiological agents

artículo científico publicado en 2017

Analysis of FOXP3+ regulatory T cells that display apparent viral antigen specificity during chronic hepatitis C virus infection

artículo científico publicado en 2009

Antibodies to the Plasmodium falciparum Proteins MSPDBL1 and MSPDBL2 Opsonize Merozoites, Inhibit Parasite Growth, and Predict Protection From Clinical Malaria

artículo científico publicado en 2015

Association of antibodies to Plasmodium falciparum reticulocyte binding protein homolog 5 with protection from clinical malaria

artículo científico publicado en 2014

Association of early interferon-gamma production with immunity to clinical malaria: a longitudinal study among Papua New Guinean children

artículo científico publicado en 2008

Blood-stage Plasmodium infection induces CD8+ T lymphocytes to parasite-expressed antigens, largely regulated by CD8alpha+ dendritic cells

artículo científico publicado en 2008

CD1d-restricted NKT cells contribute to malarial splenomegaly and enhance parasite-specific antibody responses

artículo científico publicado en 2003

CD4+ CD25+ regulatory T cells suppress CD4+ T-cell function and inhibit the development of Plasmodium berghei-specific TH1 responses involved in cerebral malaria pathogenesis.

artículo científico publicado en 2007

Cellular tumor necrosis factor, gamma interferon, and interleukin-6 responses as correlates of immunity and risk of clinical Plasmodium falciparum malaria in children from Papua New Guinea

artículo científico publicado en 2009

Clinical immunity to malaria

artículo científico publicado en 2006

Correction: Analysis of FOXP3+ Regulatory T Cells That Display Apparent Viral Antigen Specificity during Chronic Hepatitis C Virus Infection.

artículo científico publicado en 2012

Differential patterns of infection and disease with P. falciparum and P. vivax in young Papua New Guinean children

artículo científico publicado en 2010

Distinct protein classes including novel merozoite surface antigens in Raft-like membranes of Plasmodium falciparum

artículo científico publicado en 2005

Dysfunctional γδ T cells: a contributing factor for clinical tolerance to malaria?

artículo científico publicado en 2015

Effective adjunctive therapy by an innate defense regulatory peptide in a preclinical model of severe malaria

artículo científico publicado en 2012

Efficient measurement of opsonising antibodies to Plasmodium falciparum merozoites

artículo científico publicado en 2012

Estimating the proportion of microarray probes expressed in an RNA sample

artículo científico publicado en 2010

Evaluation of a novel magneto-optical method for the detection of malaria parasites

artículo científico publicado en 2014

Fatty acids from Plasmodium falciparum down-regulate the toxic activity of malaria glycosylphosphatidylinositols

artículo científico

Genes for glycosylphosphatidylinositol toxin biosynthesis in Plasmodium falciparum

artículo científico publicado en 2002

High yield purification of Plasmodium falciparum merozoites for use in opsonizing antibody assays

artículo científico publicado en 2014

Host reticulocytes provide metabolic reservoirs that can be exploited by malaria parasites

artículo científico publicado en 2015

IP-10-mediated T cell homing promotes cerebral inflammation over splenic immunity to malaria infection

artículo científico publicado en 2009

Identification and stoichiometry of glycosylphosphatidylinositol-anchored membrane proteins of the human malaria parasite Plasmodium falciparum

artículo científico publicado en 2006

IgG antibodies to synthetic GPI are biomarkers of immune-status to both Plasmodium falciparum and Plasmodium vivax malaria in young children

artículo científico publicado en 2017

IgG opsonization of merozoites: multiple immune mechanisms for malaria vaccine development

artículo científico publicado en 2017

Immunological processes in malaria pathogenesis.

artículo científico publicado en 2005

Improvement of culture conditions for long-term in vitro culture of Plasmodium vivax

artículo científico publicado en 2015

Influence of glycosylphosphatidylinositol anchorage on the efficacy of DNA vaccines encoding Plasmodium yoelii merozoite surface protein 4/5

artículo científico publicado en 2005

Inhibition of dendritic cell maturation by malaria is dose dependent and does not require Plasmodium falciparum erythrocyte membrane protein 1

artículo científico publicado en 2007

Intermittent preventive treatment for malaria in Papua New Guinean infants exposed to Plasmodium falciparum and P. vivax: a randomized controlled trial

artículo científico publicado en 2012

Intravascular infiltrates and organ-specific inflammation in malaria pathogenesis

artículo científico publicado en 2007

Investigation of interactions between TLR2, MyD88 and TIRAP by bioluminescence resonance energy transfer is hampered by artefacts of protein overexpression

artículo científico publicado en 2018

Mechanisms underlying early interferon-gamma production in human Plasmodium falciparum malaria

artículo científico publicado en 2009

Merozoite Antigens of Plasmodium falciparum Elicit Strain-Transcending Opsonizing Immunity

scientific article published on 16 May 2016

Metabolomics-Based Elucidation of Active Metabolic Pathways in Erythrocytes and HSC-Derived Reticulocytes

artículo científico publicado en 2017

Molecular evidence for the localization of Plasmodium falciparum immature gametocytes in bone marrow

artículo científico publicado en 2013

Murine cerebral malaria development is independent of toll-like receptor signaling

artículo científico publicado en 2007

Murine cerebral malaria: the whole story

artículo científico publicado en 2010

MyD88 is essential for clearance of Leishmania major: possible role for lipophosphoglycan and Toll‐like receptor 2 signaling

artículo científico publicado el 1 de octubre de 2003

NK cells and conventional dendritic cells engage in reciprocal activation for the induction of inflammatory responses during Plasmodium berghei ANKA infection

artículo científico publicado en 2012

NK cells stimulate recruitment of CXCR3+ T cells to the brain during Plasmodium berghei-mediated cerebral malaria.

artículo científico publicado en 2007

Natural regulatory T cells in malaria: host or parasite allies?

artículo científico publicado en 2010

Opsonising antibodies to P. falciparum merozoites associated with immunity to clinical malaria

artículo científico publicado en 2013

Plasmodium falciparum PfEMP1 Modulates Monocyte/Macrophage Transcription Factor Activation and Cytokine and Chemokine Responses

artículo científico publicado en 2017

Plasmodium falciparum erythrocyte membrane protein-1 specifically suppresses early production of host interferon-gamma

artículo científico publicado en 2007

Preferential invasion of reticulocytes during late-stage Plasmodium berghei infection accounts for reduced circulating reticulocyte levels

artículo científico publicado en 2006

Putative IKDCs are functionally and developmentally similar to natural killer cells, but not to dendritic cells

artículo científico publicado en 2007

Rational approaches to developing an anti-disease vaccine against malaria

artículo científico publicado en 2007

Regulation of immunity and pathogenesis in infectious diseases by CD1d-restricted NKT cells

artículo científico publicado en 2004

Regulation of murine cerebral malaria pathogenesis by CD1d-restricted NKT cells and the natural killer complex

artículo científico publicado en 2003

Severe malarial anemia of low parasite burden in rodent models results from accelerated clearance of uninfected erythrocytes

artículo científico publicado en 2005

Severity of anaemia is associated with bone marrow haemozoin in children exposed to Plasmodium falciparum

artículo científico publicado en 2014

Strategies for understanding and reducing the Plasmodium vivax and Plasmodium ovale hypnozoite reservoir in Papua New Guinean children: a randomised placebo-controlled trial and mathematical model

artículo científico publicado en 2015

Sulphadoxine-pyrimethamine plus azithromycin for the prevention of low birthweight in Papua New Guinea: a randomised controlled trial

artículo científico publicado en 2015

Synergistic effect of IL-12 and IL-18 induces TIM3 regulation of γδ T cell function and decreases the risk of clinical malaria in children living in Papua New Guinea

artículo científico publicado en 2017

Synthetic GPI as a candidate anti-toxic vaccine in a model of malaria

artículo científico publicado en 2002

The contribution of natural killer complex loci to the development of experimental cerebral malaria

artículo científico publicado en 2014

The lack of suppressor of cytokine signalling-1 (SOCS1) protects mice from the development of cerebral malaria caused by Plasmodium berghei ANKA.

artículo científico publicado en 2003

The natural killer complex regulates severe malarial pathogenesis and influences acquired immune responses to Plasmodium berghei ANKA.

artículo científico publicado en 2005

The risk of malarial infections and disease in Papua New Guinean children.

artículo científico publicado en 2007

The role of age and exposure to Plasmodium falciparum in the rate of acquisition of naturally acquired immunity: a randomized controlled trial

artículo científico publicado en 2012

The role of leukocytes bearing Natural Killer Complex receptors and Killer Immunoglobulin-like Receptors in the immunology of malaria

artículo científico publicado en 2007

Transcriptional profiling reveals suppressed erythropoiesis, up-regulated glycolysis, and interferon-associated responses in murine malaria.

artículo científico publicado en 2004

gammadelta-T cells expressing NK receptors predominate over NK cells and conventional T cells in the innate IFN-gamma response to Plasmodium falciparum malaria

artículo científico publicado en 2007