Lista de obras -

A malaria vaccine that elicits in humans antibodies able to kill Plasmodium falciparum

artículo científico publicado en 2005

A strong CD8+ T cell response is elicited using the synthetic polypeptide from the C-terminus of the circumsporozoite protein of Plasmodium berghei together with the adjuvant QS-21: quantitative and phenotypic comparison with the vaccine model of ir

artículo científico publicado en 2005

Acquired antibody responses against Plasmodium vivax infection vary with host genotype for duffy antigen receptor for chemokines (DARC)

artículo científico publicado en 2010

Active antiviral T-lymphocyte response can be redirected against tumor cells by antitumor antibody x MHC/viral peptide conjugates

artículo científico publicado en 2006

An update on the search for a Plasmodium vivax vaccine

artículo científico publicado en 2007

Antibody levels against GLURP R2, MSP1 block 2 hybrid and AS202.11 and the risk of malaria in children living in hyperendemic (Burkina Faso) and hypo-endemic (Ghana) areas

artículo científico publicado en 2016

Antibody-Mediated and Cellular Immune Responses Induced in Naive Volunteers by Vaccination with Long Synthetic Peptides Derived from the Plasmodium vivax Circumsporozoite Protein ⬇️

artículo científico publicado el 1 de febrero de 2011

Antigenicity and immunogenicity of a novel Plasmodium vivax circumsporozoite derived synthetic vaccine construct

artículo científico publicado en 2014

Antigenicity and immunogenicity of a novel chimeric peptide antigen based on the P. vivax circumsporozoite protein

artículo científico publicado en 2013

Assessment of antigen-specific CTL- and CD8(+)-dependent IFN-gamma responses in mice

artículo científico publicado en 2002

Biodegradable microspheres alone do not stimulate murine macrophages in vitro, but prolong antigen presentation by macrophages in vitro and stimulate a solid immune response in mice

artículo científico publicado en 2005

CSP—A Model for In Vivo Presentation of Plasmodium berghei Sporozoite Antigens by Hepatocytes ⬇️

artículo científico publicado el 18 de diciembre de 2012

Cell biological characterization of the malaria vaccine candidate trophozoite exported protein 1

artículo científico publicado en 2012

Childhood and malaria vaccines combined in biodegradable microspheres produce immunity with synergistic interactions.

artículo científico publicado en 2004

Encapsulation of peptides in biodegradable microspheres prolongs their MHC class-I presentation by dendritic cells and macrophages in vitro

artículo científico publicado en 2003

Engineering, conjugation, and immunogenicity assessment of Escherichia coli O121 O antigen for its potential use as a typhoid vaccine component ⬇️

artículo científico publicado el 6 de octubre de 2012

Evaluation of two long synthetic merozoite surface protein 2 peptides as malaria vaccine candidates

artículo científico publicado en 2009

Evidence for multiple B- and T-cell epitopes in Plasmodium falciparum liver-stage antigen 3. ⬇️

artículo científico publicado en 2009

Glutamate-rich protein (GLURP) induces antibodies that inhibit in vitro growth of Plasmodium falciparum in a phase 1 malaria vaccine trial

artículo científico publicado en 2006

Heterologous prime-boost regimen adenovector 35-circumsporozoite protein vaccine/recombinant Bacillus Calmette-Guérin expressing the Plasmodium falciparum circumsporozoite induces enhanced long-term memory immunity in BALB/c mice

artículo científico publicado en 2012

IL-12 administration leads to a transient depletion of T cells, B cells, and APCs and concomitant abrogation of the HLA-A2.1-restricted CTL response in transgenic mice

artículo científico publicado en 2002

Identification of HLA-A2 restricted CD8(+) T-lymphocyte responses to Plasmodium vivax circumsporozoite protein in individuals naturally exposed to malaria

artículo científico publicado en 2002

Identification of a conserved region of Plasmodium falciparum MSP3 targeted by biologically active antibodies to improve vaccine design

artículo científico publicado en 2004

Immunogenicity of dimorphic and C-terminal fragments of Plasmodium falciparum MSP2 formulated with different adjuvants in mice

artículo científico publicado en 2016

In vivo targeting of an anti-tumor antibody coupled to antigenic MHC class I complexes induces specific growth inhibition and regression of established syngeneic tumor grafts.

artículo científico publicado en 2003

Intranasal administration of the synthetic polypeptide from the C-terminus of the circumsporozoite protein of Plasmodium berghei with the modified heat-labile toxin of Escherichia coli (LTK63) induces a complete protection against malaria challenge

artículo científico publicado en 2008

Long synthetic peptides for the production of vaccines and drugs: a technological platform coming of age.

artículo científico publicado en 2010

Longitudinal analyses of immune responses to Plasmodium falciparum derived peptides corresponding to novel blood stage antigens in coastal Kenya

artículo científico publicado en 2008

MHC class I-restricted exogenous presentation of a synthetic 102-mer malaria vaccine polypeptide

artículo científico publicado en 2005

Malaria Vaccines: Progressing on a Bumpy Road

artículo científico publicado en 2014

Malaria vaccine candidate: design of a multivalent subunit α-helical coiled coil poly-epitope

artículo científico publicado en 2011

Malaria vaccine development using synthetic peptides as a technical platform

artículo científico publicado en 2012

Malaria vaccine: why is it taking so long?

artículo científico publicado en 2010

Malaria vaccines - The long synthetic peptide approach: Technical and conceptual advancements

artículo científico publicado en 2010

Malaria vaccines: from the laboratory to the field

artículo científico publicado en 2002

Malarial hemozoin is a Nalp3 inflammasome activating danger signal

artículo científico publicado en 2009

Medicinal application of long synthetic peptide technology

artículo científico publicado en 2004

Natural immune response to Plasmodium vivax alpha-helical coiled coil protein motifs and its association with the risk of P. vivax malaria

artículo científico publicado en 2017

Novel birch pollen specific immunotherapy formulation based on contiguous overlapping peptides

artículo científico publicado en 2013

Novel peptide inhibitors of Leishmania gp63 based on the cleavage site of MARCKS (myristoylated alanine-rich C kinase substrate)-related protein

artículo científico publicado en 2002

OM-174, a new adjuvant with a potential for human use, induces a protective response when administered with the synthetic C-terminal fragment 242–310 from the circumsporozoite protein of Plasmodium berghei ⬇️

artículo científico publicado el 2 de junio de 2003

Organization of designed nanofibrils assembled from alpha-helical peptides as determined by electron microscopy.

artículo científico publicado en 2004

Oxidative folding of synthetic polypeptides S-protected as tert-butylthio derivatives

artículo científico publicado en 2008

Peptide based malaria vaccine development: personal considerations.

artículo científico publicado en 2007

Peptide vaccination

artículo científico publicado en 2002

Phase I Safety and Immunogenicity Trial of Plasmodium vivax CS Derived Long Synthetic Peptides Adjuvanted with Montanide ISA 720 or Montanide ISA 51 ⬇️

artículo científico publicado el 1 de febrero de 2011

Phase I malaria vaccine trial with a long synthetic peptide derived from the merozoite surface protein 3 antigen

artículo científico publicado en 2005

Plasmodium berghei-infected primary hepatocytes process and present the circumsporozoite protein to specific CD8+ T cells in vitro

artículo científico publicado en 2007

Plasmodium falciparum merozoite surface protein 2: epitope mapping and fine specificity of human antibody response against non-polymorphic domains

artículo científico publicado en 2014

Plasmodium falciparum merozoite surface protein 6 displays multiple targets for naturally occurring antibodies that mediate monocyte-dependent parasite killing

artículo científico publicado en 2005

Plasmodium vivax antigen discovery based on alpha-helical coiled coil protein motif

artículo científico publicado en 2014

Plasmodium vivax thrombospondin related adhesion protein: immunogenicity and protective efficacy in rodents and Aotus monkeys

artículo científico publicado en 2007

Preclinical Vaccine Study of Plasmodium vivax Circumsporozoite Protein Derived-Synthetic Polypeptides Formulated in Montanide ISA 720 and Montanide ISA 51 Adjuvants ⬇️

artículo científico publicado el 1 de febrero de 2011

Priming of CD8(+) T Cell Responses to Liver Stage Malaria Parasite Antigens

artículo científico publicado en 2014

Protection against Plasmodium falciparum challenge induced in Aotus monkeys by liver-stage antigen-3-derived long synthetic peptides

artículo científico publicado en 2008

Protein structure based strategies for antigen discovery and vaccine development against malaria and other pathogens.

artículo científico publicado en 2007

Rapid identification of malaria vaccine candidates based on alpha-helical coiled coil protein motif

artículo científico publicado en 2007

Recognition of synthetic polypeptides corresponding to the N- and C-terminal fragments of Plasmodium falciparum Exp-1 by T-cells and plasma from human donors from African endemic areas

artículo científico publicado en 2002

Safety and elicitation of humoral and cellular responses in colombian malaria-naive volunteers by a Plasmodium vivax circumsporozoite protein-derived synthetic vaccine

artículo científico publicado en 2005

Sequence conservation in Plasmodium falciparum alpha-helical coiled coil domains proposed for vaccine development

artículo científico publicado en 2009

Sporozoite-mediated hepatocyte wounding limits Plasmodium parasite development via MyD88-mediated NF-kappa B activation and inducible NO synthase expression

artículo científico publicado en 2008

Sterile protection against malaria is independent of immune responses to the circumsporozoite protein

artículo científico publicado en 2007

Strain-transcending Fc-dependent killing of Plasmodium falciparum by merozoite surface protein 2 allele-specific human antibodies

artículo científico publicado en 2010

Sustained activation and tumor targeting of NKT cells using a CD1d-anti-HER2-scFv fusion protein induce antitumor effects in mice

artículo científico publicado en 2008

Synthetic RGD-containing alpha-helical coiled coil peptides promote integrin-dependent cell adhesion

artículo científico publicado en 2006

The C-terminal domain of Plasmodium falciparum merozoite surface protein 3 self-assembles into alpha-helical coiled coil tetramer

artículo científico publicado en 2009

The Candidate Blood Stage Malaria Vaccine P27A Induces a Robust Humoral Response in a Fast Track to the Field Phase I Trial in Exposed and Non Exposed Volunteers

scholarly article by Viviane Steiner-Monard et al published 26 June 2018 in Clinical Infectious Diseases

The N-terminal domain of Plasmodium falciparum circumsporozoite protein represents a target of protective immunity

artículo científico publicado en 2008

The functional half-life of H-2Kd-restricted T cell epitopes on living cells

scholarly article by Gérard Eberl et al published September 1996 in European Journal of Immunology

The malaria circumsporozoite protein has two functional domains, each with distinct roles as sporozoites journey from mosquito to mammalian host ⬇️

artículo científico publicado el 24 de enero de 2011

The synthetic Plasmodium falciparum circumsporozoite peptide PfCS102 as a malaria vaccine candidate: a randomized controlled phase I trial

artículo científico publicado en 2009

The use of a P. falciparum specific coiled-coil domain to construct a self-assembling protein nanoparticle vaccine to prevent malaria

artículo científico publicado en 2017

Use of long synthetic peptides to study the antigenicity and immunogenicity of the Plasmodium vivax circumsporozoite protein

artículo científico publicado en 2004

Lista de obras de

A malaria vaccine that elicits in humans antibodies able to kill Plasmodium falciparum

A strong CD8+ T cell response is elicited using the synthetic polypeptide from the C-terminus of the circumsporozoite protein of Plasmodium berghei together with the adjuvant QS-21: quantitative and phenotypic comparison with the vaccine model of ir

Acquired antibody responses against Plasmodium vivax infection vary with host genotype for duffy antigen receptor for chemokines (DARC)

Active antiviral T-lymphocyte response can be redirected against tumor cells by antitumor antibody x MHC/viral peptide conjugates

An update on the search for a Plasmodium vivax vaccine

Antibody levels against GLURP R2, MSP1 block 2 hybrid and AS202.11 and the risk of malaria in children living in hyperendemic (Burkina Faso) and hypo-endemic (Ghana) areas

Antibody-Mediated and Cellular Immune Responses Induced in Naive Volunteers by Vaccination with Long Synthetic Peptides Derived from the Plasmodium vivax Circumsporozoite Protein ⬇️

Antigenicity and immunogenicity of a novel Plasmodium vivax circumsporozoite derived synthetic vaccine construct

Antigenicity and immunogenicity of a novel chimeric peptide antigen based on the P. vivax circumsporozoite protein

Assessment of antigen-specific CTL- and CD8(+)-dependent IFN-gamma responses in mice

Biodegradable microspheres alone do not stimulate murine macrophages in vitro, but prolong antigen presentation by macrophages in vitro and stimulate a solid immune response in mice

CSP—A Model for In Vivo Presentation of Plasmodium berghei Sporozoite Antigens by Hepatocytes ⬇️

Cell biological characterization of the malaria vaccine candidate trophozoite exported protein 1

Childhood and malaria vaccines combined in biodegradable microspheres produce immunity with synergistic interactions.

Encapsulation of peptides in biodegradable microspheres prolongs their MHC class-I presentation by dendritic cells and macrophages in vitro

Engineering, conjugation, and immunogenicity assessment of Escherichia coli O121 O antigen for its potential use as a typhoid vaccine component ⬇️

Evaluation of two long synthetic merozoite surface protein 2 peptides as malaria vaccine candidates

Evidence for multiple B- and T-cell epitopes in Plasmodium falciparum liver-stage antigen 3. ⬇️

Glutamate-rich protein (GLURP) induces antibodies that inhibit in vitro growth of Plasmodium falciparum in a phase 1 malaria vaccine trial

Heterologous prime-boost regimen adenovector 35-circumsporozoite protein vaccine/recombinant Bacillus Calmette-Guérin expressing the Plasmodium falciparum circumsporozoite induces enhanced long-term memory immunity in BALB/c mice

IL-12 administration leads to a transient depletion of T cells, B cells, and APCs and concomitant abrogation of the HLA-A2.1-restricted CTL response in transgenic mice

Identification of HLA-A2 restricted CD8(+) T-lymphocyte responses to Plasmodium vivax circumsporozoite protein in individuals naturally exposed to malaria

Identification of a conserved region of Plasmodium falciparum MSP3 targeted by biologically active antibodies to improve vaccine design

Immunogenicity of dimorphic and C-terminal fragments of Plasmodium falciparum MSP2 formulated with different adjuvants in mice

In vivo targeting of an anti-tumor antibody coupled to antigenic MHC class I complexes induces specific growth inhibition and regression of established syngeneic tumor grafts.

Intranasal administration of the synthetic polypeptide from the C-terminus of the circumsporozoite protein of Plasmodium berghei with the modified heat-labile toxin of Escherichia coli (LTK63) induces a complete protection against malaria challenge

Long synthetic peptides for the production of vaccines and drugs: a technological platform coming of age.

Longitudinal analyses of immune responses to Plasmodium falciparum derived peptides corresponding to novel blood stage antigens in coastal Kenya

MHC class I-restricted exogenous presentation of a synthetic 102-mer malaria vaccine polypeptide

Malaria Vaccines: Progressing on a Bumpy Road

Malaria vaccine candidate: design of a multivalent subunit α-helical coiled coil poly-epitope

Malaria vaccine development using synthetic peptides as a technical platform

Malaria vaccine: why is it taking so long?

Malaria vaccines - The long synthetic peptide approach: Technical and conceptual advancements

Malaria vaccines: from the laboratory to the field

Malarial hemozoin is a Nalp3 inflammasome activating danger signal

Medicinal application of long synthetic peptide technology

Natural immune response to Plasmodium vivax alpha-helical coiled coil protein motifs and its association with the risk of P. vivax malaria

Novel birch pollen specific immunotherapy formulation based on contiguous overlapping peptides

Novel peptide inhibitors of Leishmania gp63 based on the cleavage site of MARCKS (myristoylated alanine-rich C kinase substrate)-related protein

OM-174, a new adjuvant with a potential for human use, induces a protective response when administered with the synthetic C-terminal fragment 242–310 from the circumsporozoite protein of Plasmodium berghei ⬇️

Organization of designed nanofibrils assembled from alpha-helical peptides as determined by electron microscopy.

Oxidative folding of synthetic polypeptides S-protected as tert-butylthio derivatives

Peptide based malaria vaccine development: personal considerations.

Peptide vaccination

Phase I Safety and Immunogenicity Trial of Plasmodium vivax CS Derived Long Synthetic Peptides Adjuvanted with Montanide ISA 720 or Montanide ISA 51 ⬇️

Phase I malaria vaccine trial with a long synthetic peptide derived from the merozoite surface protein 3 antigen

Plasmodium berghei-infected primary hepatocytes process and present the circumsporozoite protein to specific CD8+ T cells in vitro

Plasmodium falciparum merozoite surface protein 2: epitope mapping and fine specificity of human antibody response against non-polymorphic domains

Plasmodium falciparum merozoite surface protein 6 displays multiple targets for naturally occurring antibodies that mediate monocyte-dependent parasite killing

Plasmodium vivax antigen discovery based on alpha-helical coiled coil protein motif

Plasmodium vivax thrombospondin related adhesion protein: immunogenicity and protective efficacy in rodents and Aotus monkeys

Preclinical Vaccine Study of Plasmodium vivax Circumsporozoite Protein Derived-Synthetic Polypeptides Formulated in Montanide ISA 720 and Montanide ISA 51 Adjuvants ⬇️

Priming of CD8(+) T Cell Responses to Liver Stage Malaria Parasite Antigens

Protection against Plasmodium falciparum challenge induced in Aotus monkeys by liver-stage antigen-3-derived long synthetic peptides

Protein structure based strategies for antigen discovery and vaccine development against malaria and other pathogens.

Rapid identification of malaria vaccine candidates based on alpha-helical coiled coil protein motif

Recognition of synthetic polypeptides corresponding to the N- and C-terminal fragments of Plasmodium falciparum Exp-1 by T-cells and plasma from human donors from African endemic areas

Safety and elicitation of humoral and cellular responses in colombian malaria-naive volunteers by a Plasmodium vivax circumsporozoite protein-derived synthetic vaccine

Sequence conservation in Plasmodium falciparum alpha-helical coiled coil domains proposed for vaccine development

Sporozoite-mediated hepatocyte wounding limits Plasmodium parasite development via MyD88-mediated NF-kappa B activation and inducible NO synthase expression

Sterile protection against malaria is independent of immune responses to the circumsporozoite protein

Strain-transcending Fc-dependent killing of Plasmodium falciparum by merozoite surface protein 2 allele-specific human antibodies

Sustained activation and tumor targeting of NKT cells using a CD1d-anti-HER2-scFv fusion protein induce antitumor effects in mice

Synthetic RGD-containing alpha-helical coiled coil peptides promote integrin-dependent cell adhesion

The C-terminal domain of Plasmodium falciparum merozoite surface protein 3 self-assembles into alpha-helical coiled coil tetramer

The Candidate Blood Stage Malaria Vaccine P27A Induces a Robust Humoral Response in a Fast Track to the Field Phase I Trial in Exposed and Non Exposed Volunteers

The N-terminal domain of Plasmodium falciparum circumsporozoite protein represents a target of protective immunity

The functional half-life of H-2Kd-restricted T cell epitopes on living cells

The malaria circumsporozoite protein has two functional domains, each with distinct roles as sporozoites journey from mosquito to mammalian host ⬇️

The synthetic Plasmodium falciparum circumsporozoite peptide PfCS102 as a malaria vaccine candidate: a randomized controlled phase I trial

The use of a P. falciparum specific coiled-coil domain to construct a self-assembling protein nanoparticle vaccine to prevent malaria

Use of long synthetic peptides to study the antigenicity and immunogenicity of the Plasmodium vivax circumsporozoite protein