Lista de obras - Wolfram Bode - Dominio Público Uruguay

(R)-3-Amidinophenylalanine-derived inhibitors of factor Xa with a novel active-site binding mode

artículo científico publicado en 2002

1.2 A crystal structure of the serine carboxyl proteinase pro-kumamolisin; structure of an intact pro-subtilase

artículo científico publicado en 2004

157 The “activation domain”: A highly cooperative entity within the catalytic domain of serine proteinases

A standard orientation for metallopeptidases ⬇️

artículo científico publicado el 30 de abril de 2011

Catalytic Domain Structures of MT-SP1/Matriptase, a Matrix-degrading Transmembrane Serine Proteinase ⬇️

artículo científico publicado el 5 de noviembre de 2001

Characterization of the residues involved in the human alpha-thrombin-haemadin complex: an exosite II-binding inhibitor

artículo científico publicado en 2002

Chymotryptic specificity determinants in the 1.0 A structure of the zinc-inhibited human tissue kallikrein 7

artículo científico publicado en 2007

Cloning, expression, crystallization and initial crystallographic analysis of the C-terminal domain of the amyloid precursor protein APP.

artículo científico publicado en 2004

Conformational Variability of Chicken Cystatin

article

Crystal structure of human carboxypeptidase M, a membrane-bound enzyme that regulates peptide hormone activity

artículo científico publicado en 2004

Crystal structure of the apoptosis-inducing human granzyme A dimer

artículo científico publicado en 2003

Crystal structure of the dinuclear zinc aminopeptidase PepV from Lactobacillus delbrueckii unravels its preference for dipeptides

artículo científico publicado en 2002

Crystal structure of the human carboxypeptidase N (kininase I) catalytic domain

artículo científico publicado en 2007

Crystal structures of MMP-9 complexes with five inhibitors: contribution of the flexible Arg424 side-chain to selectivity

artículo científico publicado en 2007

Crystal structures of human tissue kallikrein 4: activity modulation by a specific zinc binding site.

artículo científico publicado en 2006

Crystal structures of uninhibited factor VIIa link its cofactor and substrate-assisted activation to specific interactions

artículo científico publicado en 2002

Crystallization and preliminary X-ray analysis of recombinant full-length human m-calpain

artículo científico publicado en 2000

Crystals of urokinase type plasminogen activator complexes reveal the binding mode of peptidomimetic inhibitors

artículo científico publicado en 2003

Direct interaction between a human digestive protease and the mucoadhesive poly(acrylic acid)

artículo científico publicado en 2008

Fibrinogen substrate recognition by staphylocoagulase.(pro)thrombin complexes

artículo científico publicado en 2006

Flexibility analysis and structure comparison of two crystal forms of calcium-free human m-calpain

artículo científico publicado en 2002

Identification of a beta-secretase activity, which truncates amyloid beta-peptide after its presenilin-dependent generation

artículo científico publicado en 2002

Inhibition of furin by polyarginine-containing peptides: nanomolar inhibition by nona-D-arginine

artículo científico publicado en 2004

Interplay of human tissue kallikrein 4 (hK4) with the plasminogen activation system: hK4 regulates the structure and functions of the urokinase-type plasminogen activator receptor (uPAR).

artículo científico publicado en 2006

Macrocyclic statine-based inhibitors of BACE-1.

artículo científico publicado en 2007

Mutations of the PC2 substrate binding pocket alter enzyme specificity

artículo científico publicado en 2005

Novel fluorescent prothrombin analogs as probes of staphylocoagulase-prothrombin interactions

artículo científico publicado en 2006

Physiological fIXa activation involves a cooperative conformational rearrangement of the 99-loop

artículo científico publicado en 2002

Pore-forming scissors? A first structural glimpse of gamma-secretase

artículo científico publicado en 2006

Properties of purified gut trypsin from Helicoverpa zea, adapted to proteinase inhibitors

artículo científico publicado en 2003

Proprotein convertase models based on the crystal structures of furin and kexin: explanation of their specificity

artículo científico publicado en 2005

Rigidity and flexibility of dipeptidyl peptidase IV: crystal structures of and docking experiments with DPIV.

artículo científico publicado en 2005

Specific inhibition of insect alpha-amylases: yellow meal worm alpha-amylase in complex with the amaranth alpha-amylase inhibitor at 2.0 A resolution

artículo científico publicado en 1999

Specificity profiling of seven human tissue kallikreins reveals individual subsite preferences

artículo científico publicado en 2006

Staphylocoagulase is a prototype for the mechanism of cofactor-induced zymogen activation

artículo científico publicado en 2003

Structural basis for reduced staphylocoagulase-mediated bovine prothrombin activation

artículo científico publicado en 2005

Structural basis for the Zn2+ inhibition of the zymogen-like kallikrein-related peptidase 10

artículo científico publicado en 2016

Structural basis for the sheddase function of human meprin metalloproteinase at the plasma membrane

artículo científico publicado en 2012

Structural basis of matrix metalloproteinase function ⬇️

artículo científico publicado el 1 de enero de 2003

Structural basis of matrix metalloproteinases and tissue inhibitors of metalloproteinases

artículo científico publicado en 2003

Structural basis of the activation and action of trypsin

article

Structural basis of the matrix metalloproteinases and their physiological inhibitors, the tissue inhibitors of metalloproteinases

artículo científico publicado en 2003

Structural basis of the zinc inhibition of human tissue kallikrein 5

artículo científico publicado en 2007

Structural determinants of specificity and regulation of activity in the allosteric loop network of human KLK8/neuropsin.

artículo científico publicado en 2018

Structural determinants of the ADAM inhibition by TIMP-3: crystal structure of the TACE-N-TIMP-3 complex

artículo científico publicado en 2008

Structural implications for the role of the N terminus in the ‘superactivation’ of collagenases

article

Structure and interaction modes of thrombin

artículo científico publicado en 2006

Structure of a novel thrombin inhibitor with an uncharged D-amino acid as P1 residue

artículo científico publicado en 2007

Structures and specificity of the human kallikrein-related peptidases KLK 4, 5, 6, and 7.

artículo científico publicado en 2008

The 1.4 a crystal structure of kumamolysin: a thermostable serine-carboxyl-type proteinase

artículo científico publicado en 2002

The 1.9-A crystal structure of the noncollagenous (NC1) domain of human placenta collagen IV shows stabilization via a novel type of covalent Met-Lys cross-link

artículo científico publicado en 2002

The 2.2-A crystal structure of human pro-granzyme K reveals a rigid zymogen with unusual features

artículo científico publicado en 2002

The Dimer Interface of the Membrane Type 1 Matrix Metalloproteinase Hemopexin Domain: CRYSTAL STRUCTURE AND BIOLOGICAL FUNCTIONS

artículo científico publicado en 2011

The NC1 dimer of human placental basement membrane collagen IV: does a covalent crosslink exist?

artículo científico publicado en 2005

The crystal structure of dipeptidyl peptidase IV (CD26) reveals its functional regulation and enzymatic mechanism

artículo científico publicado en 2003

The crystal structure of human alpha1-tryptase reveals a blocked substrate-binding region

artículo científico publicado en 2002

The crystal structure of the proprotein processing proteinase furin explains its stringent specificity

artículo científico publicado en 2003

The factor V C1 domain is involved in membrane binding: identification of functionally important amino acid residues within the C1 domain of factor V using alanine scanning mutagenesis

artículo científico publicado en 2004

The influence of residue 190 in the S1 site of trypsin-like serine proteases on substrate selectivity is universally conserved

artículo científico publicado en 2002

The methyl group of N(alpha)(Me)Arg-containing peptides disturbs the active-site geometry of thrombin, impairing efficient cleavage

artículo científico publicado en 2002

The structure of thrombin: a janus-headed proteinase

artículo científico publicado en 2006

Thermodynamic linkage between the S1 site, the Na+ site, and the Ca2+ site in the protease domain of human activated protein C (APC). Sodium ion in the APC crystal structure is coordinated to four carbonyl groups from two separate loops

artículo científico publicado en 2002

Thrombin inhibitors identified by computer-assisted multiparameter design

artículo científico publicado en 2005

X-ray structure of human proMMP-1: new insights into procollagenase activation and collagen binding

artículo científico publicado en 2004

X-ray structure of isoaspartyl dipeptidase from E.coli: a dinuclear zinc peptidase evolved from amidohydrolases

artículo científico publicado en 2003

X-ray structures of free and leupeptin-complexed human alphaI-tryptase mutants: indication for an alpha-->beta-tryptase transition

artículo científico publicado en 2005

Lista de obras de Wolfram Bode

(R)-3-Amidinophenylalanine-derived inhibitors of factor Xa with a novel active-site binding mode

1.2 A crystal structure of the serine carboxyl proteinase pro-kumamolisin; structure of an intact pro-subtilase

157 The “activation domain”: A highly cooperative entity within the catalytic domain of serine proteinases

A standard orientation for metallopeptidases ⬇️

Catalytic Domain Structures of MT-SP1/Matriptase, a Matrix-degrading Transmembrane Serine Proteinase ⬇️

Characterization of the residues involved in the human alpha-thrombin-haemadin complex: an exosite II-binding inhibitor

Chymotryptic specificity determinants in the 1.0 A structure of the zinc-inhibited human tissue kallikrein 7

Cloning, expression, crystallization and initial crystallographic analysis of the C-terminal domain of the amyloid precursor protein APP.

Conformational Variability of Chicken Cystatin

Crystal structure of human carboxypeptidase M, a membrane-bound enzyme that regulates peptide hormone activity

Crystal structure of the apoptosis-inducing human granzyme A dimer

Crystal structure of the dinuclear zinc aminopeptidase PepV from Lactobacillus delbrueckii unravels its preference for dipeptides

Crystal structure of the human carboxypeptidase N (kininase I) catalytic domain

Crystal structures of MMP-9 complexes with five inhibitors: contribution of the flexible Arg424 side-chain to selectivity

Crystal structures of human tissue kallikrein 4: activity modulation by a specific zinc binding site.

Crystal structures of uninhibited factor VIIa link its cofactor and substrate-assisted activation to specific interactions

Crystallization and preliminary X-ray analysis of recombinant full-length human m-calpain

Crystals of urokinase type plasminogen activator complexes reveal the binding mode of peptidomimetic inhibitors

Direct interaction between a human digestive protease and the mucoadhesive poly(acrylic acid)

Fibrinogen substrate recognition by staphylocoagulase.(pro)thrombin complexes

Flexibility analysis and structure comparison of two crystal forms of calcium-free human m-calpain

Identification of a beta-secretase activity, which truncates amyloid beta-peptide after its presenilin-dependent generation

Inhibition of furin by polyarginine-containing peptides: nanomolar inhibition by nona-D-arginine

Interplay of human tissue kallikrein 4 (hK4) with the plasminogen activation system: hK4 regulates the structure and functions of the urokinase-type plasminogen activator receptor (uPAR).

Macrocyclic statine-based inhibitors of BACE-1.

Mutations of the PC2 substrate binding pocket alter enzyme specificity

Novel fluorescent prothrombin analogs as probes of staphylocoagulase-prothrombin interactions

Physiological fIXa activation involves a cooperative conformational rearrangement of the 99-loop

Pore-forming scissors? A first structural glimpse of gamma-secretase

Properties of purified gut trypsin from Helicoverpa zea, adapted to proteinase inhibitors

Proprotein convertase models based on the crystal structures of furin and kexin: explanation of their specificity

Rigidity and flexibility of dipeptidyl peptidase IV: crystal structures of and docking experiments with DPIV.

Specific inhibition of insect alpha-amylases: yellow meal worm alpha-amylase in complex with the amaranth alpha-amylase inhibitor at 2.0 A resolution

Specificity profiling of seven human tissue kallikreins reveals individual subsite preferences

Staphylocoagulase is a prototype for the mechanism of cofactor-induced zymogen activation

Structural basis for reduced staphylocoagulase-mediated bovine prothrombin activation

Structural basis for the Zn2+ inhibition of the zymogen-like kallikrein-related peptidase 10

Structural basis for the sheddase function of human meprin metalloproteinase at the plasma membrane

Structural basis of matrix metalloproteinase function ⬇️

Structural basis of matrix metalloproteinases and tissue inhibitors of metalloproteinases

Structural basis of the activation and action of trypsin

Structural basis of the matrix metalloproteinases and their physiological inhibitors, the tissue inhibitors of metalloproteinases

Structural basis of the zinc inhibition of human tissue kallikrein 5

Structural determinants of specificity and regulation of activity in the allosteric loop network of human KLK8/neuropsin.

Structural determinants of the ADAM inhibition by TIMP-3: crystal structure of the TACE-N-TIMP-3 complex

Structural implications for the role of the N terminus in the ‘superactivation’ of collagenases

Structure and interaction modes of thrombin

Structure of a novel thrombin inhibitor with an uncharged D-amino acid as P1 residue

Structures and specificity of the human kallikrein-related peptidases KLK 4, 5, 6, and 7.

The 1.4 a crystal structure of kumamolysin: a thermostable serine-carboxyl-type proteinase

The 1.9-A crystal structure of the noncollagenous (NC1) domain of human placenta collagen IV shows stabilization via a novel type of covalent Met-Lys cross-link

The 2.2-A crystal structure of human pro-granzyme K reveals a rigid zymogen with unusual features

The Dimer Interface of the Membrane Type 1 Matrix Metalloproteinase Hemopexin Domain: CRYSTAL STRUCTURE AND BIOLOGICAL FUNCTIONS

The NC1 dimer of human placental basement membrane collagen IV: does a covalent crosslink exist?

The crystal structure of dipeptidyl peptidase IV (CD26) reveals its functional regulation and enzymatic mechanism

The crystal structure of human alpha1-tryptase reveals a blocked substrate-binding region

The crystal structure of the proprotein processing proteinase furin explains its stringent specificity

The factor V C1 domain is involved in membrane binding: identification of functionally important amino acid residues within the C1 domain of factor V using alanine scanning mutagenesis

The influence of residue 190 in the S1 site of trypsin-like serine proteases on substrate selectivity is universally conserved

The methyl group of N(alpha)(Me)Arg-containing peptides disturbs the active-site geometry of thrombin, impairing efficient cleavage

The structure of thrombin: a janus-headed proteinase

Thermodynamic linkage between the S1 site, the Na+ site, and the Ca2+ site in the protease domain of human activated protein C (APC). Sodium ion in the APC crystal structure is coordinated to four carbonyl groups from two separate loops

Thrombin inhibitors identified by computer-assisted multiparameter design

X-ray structure of human proMMP-1: new insights into procollagenase activation and collagen binding

X-ray structure of isoaspartyl dipeptidase from E.coli: a dinuclear zinc peptidase evolved from amidohydrolases

X-ray structures of free and leupeptin-complexed human alphaI-tryptase mutants: indication for an alpha-->beta-tryptase transition