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"Reverse ecology" and the power of population genomics

artículo científico publicado en 2008

<i>MAP3K7</i> Loss Drives Enhanced Androgen Signaling and Independently Confers Risk of Recurrence in Prostate Cancer with Joint Loss of <i>CHD1</i>

artículo científico publicado en 2021

A DREAM Challenge to Build Prediction Models for Short-Term Discontinuation of Docetaxel in Metastatic Castration-Resistant Prostate Cancer

scientific article published on 01 November 2017

A Gene Expression Signature Predicts Bladder Cancer Cell Line Sensitivity to EGFR Inhibition

artículo científico publicado en 2018

A SIX1/EYA2 small molecule inhibitor disrupts EMT and metastasis

scientific article published on 27 April 2020

A SPATIOTEMPORAL MODEL TO SIMULATE CHEMOTHERAPY REGIMENS FOR HETEROGENEOUS BLADDER CANCER METASTASES TO THE LUNG.

artículo científico publicado en 2017

A Whole-genome CRISPR Screen Identifies a Role of MSH2 in Cisplatin-mediated Cell Death in Muscle-invasive Bladder Cancer

artículo científico publicado en 2018

All Paths Lead to TRIM25.

artículo científico publicado en 2017

Allele-Specific DNA Methylation and Its Interplay with Repressive Histone Marks at Promoter-Mutant TERT Genes.

artículo científico publicado en 2017

Bactericidal antibiotics induce mitochondrial dysfunction and oxidative damage in Mammalian cells.

scientific article published on July 2013

Combined administration of testosterone plus an ornithine decarboxylase inhibitor as a selective prostate-sparing anabolic therapy

artículo científico publicado en 2013

Community mining of open clinical trial data.

artículo científico publicado en 2017

Concurrent alterations in TERT, KDM6A, and the BRCA pathway in bladder cancer.

artículo científico publicado en 2014

Coordinate loss of MAP3K7 and CHD1 promotes aggressive prostate cancer

artículo científico publicado en 2015

Crowdsourcing biomedical research: leveraging communities as innovation engines

artículo científico publicado en 2016

DREAMTools: a Python package for scoring collaborative challenges.

artículo científico publicado en 2015

Data pushing: a fly-centric guide to bioinformatics tools.

artículo científico publicado en 2008

Decade in review-bladder cancer: international progress: from cytology to genomics.

artículo científico publicado en 2014

Differential splicing across immune system lineages

artículo científico publicado en 2013

EST and microarray analysis of horn development in Onthophagus beetles

artículo científico publicado en 2009

Eya3 promotes breast tumor-associated immune suppression via threonine phosphatase-mediated PD-L1 upregulation

scientific article published on 14 May 2018

GON4L Drives Cancer Growth through a YY1-Androgen Receptor-CD24 Axis

artículo científico publicado en 2016

GSEA-InContext: identifying novel and common patterns in expression experiments.

artículo científico publicado en 2018

Gene networks in Drosophila melanogaster: integrating experimental data to predict gene function

artículo científico publicado en 2009

Homeoprotein Six2 promotes breast cancer metastasis via transcriptional and epigenetic control of E-cadherin expression

artículo científico publicado en 2014

Induction of ADAM10 by Radiation Therapy Drives Fibrosis, Resistance, and Epithelial-to-Mesenchyal Transition in Pancreatic Cancer

publication published on 01 February 2021

KDM3A/Ets1 epigenetic axis contributes to PAX3/FOXO1-driven and independent disease-promoting gene expression in fusion-positive Rhabdomyosarcoma

artículo científico publicado en 2020

Loss of MAP3K7 Sensitizes Prostate Cancer Cells to CDK1/2 Inhibition and DNA Damage by Disrupting Homologous Recombination

scientific article published on 12 July 2019

Mediator of DNA Damage Checkpoint 1 (MDC1) Is a Novel Estrogen Receptor Coregulator in Invasive Lobular Carcinoma of the Breast

artículo científico publicado en 2021

Mesenchymal and MAPK Expression Signatures Associate with Telomerase Promoter Mutations in Multiple Cancers

scientific article published on 10 April 2020

Metastatic cells are preferentially vulnerable to lysosomal inhibition

scientific article published on 20 August 2018

Molecular analysis of urothelial cancer cell lines for modeling tumor biology and drug response

artículo científico publicado en 2016

Monocytic Subclones Confer Resistance to Venetoclax-Based Therapy in Patients with Acute Myeloid Leukemia

scientific article published on 23 January 2020

Multivalent Chromatin Engagement and Inter-domain Crosstalk Regulate MORC3 ATPase.

artículo científico publicado en 2016

Next-Generation Machine Learning for Biological Networks

artículo científico publicado en 2018

Prediction of overall survival for patients with metastatic castration-resistant prostate cancer: development of a prognostic model through a crowdsourced challenge with open clinical trial data

artículo científico publicado en 2016

Research resource: EPSLiM: ensemble predictor for short linear motifs in nuclear hormone receptors.

artículo científico publicado en 2014

RhoC Is an Unexpected Target of RhoGDI2 in Prevention of Lung Colonization of Bladder Cancer.

artículo científico publicado en 2014

SIX2 Mediates Late-Stage Metastasis via Direct Regulation of SOX2 and Induction of a Cancer Stem Cell Program

scientific article published on 03 January 2019

Seeking the wisdom of crowds through challenge-based competitions in biomedical research.

artículo científico publicado en 2013

Simulating heterogeneous populations using Boolean models.

artículo científico publicado en 2018

Systematic Review: Characteristics and Preclinical Uses of Bladder Cancer Cell Lines.

artículo científico publicado en 2018

Targeting DDR2 enhances tumor response to anti-PD-1 immunotherapy

article

The capacity of the ovarian cancer tumor microenvironment to integrate inflammation signaling conveys a shorter disease-free interval

scientific article published on 14 September 2020

Trisomy 21 activates the kynurenine pathway via increased dosage of interferon receptors

artículo científico publicado en 2019

Troubleshooting microarray hybridizations.

artículo científico publicado en 2006

Tumor-Derived Cell Lines as Molecular Models of Cancer Pharmacogenomics

artículo científico publicado en 2016