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A conformationally frozen peptoid boosts CXCR4 affinity and anti-HIV activity

artículo científico publicado en 2012

A high-throughput fluorescence polarization anisotropy assay for the 70N domain of replication protein A.

artículo científico publicado en 2011

Biophysics: the sweetest candy for the virus.

artículo científico publicado en 2008

Conformational Control of Integrin-Subtype Selectivity in isoDGR Peptide Motifs: A Biological Switch

artículo científico publicado en 2010

Deuterated polymer gels for measuring anisotropic NMR parameters with strongly reduced artefacts.

artículo científico publicado en 2008

Direct prediction of residual dipolar couplings of small molecules in a stretched gel by stochastic molecular dynamics simulations

artículo científico publicado en 2015

Discovery of Protein–Protein Interaction Inhibitors of Replication Protein A

artículo científico publicado en 2013

Discovery of a Potent Inhibitor of Replication Protein A Protein–Protein Interactions Using a Fragment-Linking Approach

artículo científico publicado en 2013

Discovery of a Potent Stapled Helix Peptide That Binds to the 70N Domain of Replication Protein A

artículo científico publicado en 2014

First Crystal Structure of a Nonstructural Hepatitis E Viral Protein Identifies a Putative Novel Zinc-Binding Protein

scientific article published on 14 June 2019

Fragment-based drug discovery using NMR spectroscopy

artículo científico publicado en 2013

Identification and Optimization of Anthranilic Acid Based Inhibitors of Replication Protein A

artículo científico publicado en 2016

Increasing αvβ3 selectivity of the anti-angiogenic drug cilengitide by N-methylation.

artículo científico publicado en 2011

Intestinal permeability of cyclic peptides: common key backbone motifs identified.

artículo científico publicado en 2012

Making double-minded peptides strong-willed? The side chain impact on the backbone conformation of N-methylated cyclic pentapeptides.

artículo científico publicado en 2009

Receptor-Bound Conformation of Cilengitide Better Represented by Its Solution-State Structure than the Solid-State Structure

scientific article published on 22 September 2014

Selective Methyl Labeling of Proteins: Enabling Structural and Mechanistic Studies As Well As Drug Discovery Applications by Solution-State NMR

artículo científico publicado en 2018

Surface Reengineering of RPA70N Enables Cocrystallization with an Inhibitor of the Replication Protein A Interaction Motif of ATR Interacting Protein

artículo científico publicado en 2013

Synthesis and biological evaluation of phosphino dipeptide isostere inhibitor of human beta-secretase (BACE1)

artículo científico publicado en 2007

The Impact of Amino Acid Side Chain Mutations in Conformational Design of Peptides and Proteins

artículo científico publicado en 2010

cis-Peptide Bonds: A Key for Intestinal Permeability of Peptides? .

artículo científico publicado en 2015