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2,3,7,8-Tetrachlorodibenzo-p-dioxin-induced degradation of aryl hydrocarbon receptor (AhR) by the ubiquitin-proteasome pathway: role of the transcription activaton and DNA binding of AhR ⬇️

artículo científico publicado en 2000

A cycloheximide-sensitive factor regulates TCDD-induced degradation of the aryl hydrocarbon receptor

artículo científico publicado en 2002

A labile factor regulates induction of NQOR by TCDD and phenolic antioxidants ⬇️

abstract published in 2001

Accelerated ovarian failure induced by 4-vinyl cyclohexene diepoxide in Nrf2 null mice

artículo científico publicado en 2006

Activation of Nrf2 in defense against cadmium-induced oxidative stress

artículo científico publicado en 2008

Advances in mechanisms and signaling pathways of carbon nanotube toxicity

artículo científico publicado en 2015

Advances in mechanisms of anti-oxidation ⬇️

artículo científico publicado en 2014

Ah receptor interacts with Nrf2 to mediate the induction of NQO1 by 2,3,7,8-tetrachlorodibenzo-p-dioxin and benzo[a]pyrene ⬇️

abstract published in 2011

Ah receptor: xenobiotic response meets inflammation

artículo científico

Alterations in gene expression as a mechanism of toxicant ⬇️

abstract published in 2002

Arsenic binds to redox sensor protein Keap1 directly through the thiol groups of critical cysteines in the linker region of Keap1 ⬇️

conference abstract published in 2008

Arsenic induces NAD(P)H-quinone oxidoreductase I by disrupting the Nrf2·Keap1·Cul3 complex and recruiting Nrf2·Maf to the antioxidant response element enhancer

artículo científico publicado en 2006

Aryl hydrocarbon receptor degradation-promoting factor (ADPF) and the control of the xenobiotic response

artículo científico publicado en 2007

CYP1A induction and human risk assessment: an evolving tale of in vitro and in vivo studies

artículo científico publicado en 2007

Cadmium coordinates up-regulation of cytoprotective genes and protection agains metal toxicity by inhibiting the ubiquitination of Nrf2 and disrupting the Nrf2/Keap1 complex ⬇️

conference abstract published in 2007

Carbon nanotubes and crystalline silica induce matrix remodeling and contraction by stimulating myofibroblast transformation in a three-dimensional culture of human pulmonary fibroblasts: role of dimension and rigidity

artículo científico publicado en 2018

Carbon nanotubes and crystalline silica stimulate robust ROS production, inflammasome activation, and IL-1β secretion in macrophages to induce myofibroblast transformation

journal article published in 2019

Chemoprotection by phenolic antioxidants ⬇️

artículo científico publicado en 2002

Chromium (VI) induces antioxidant gene HO-1 by activating the CNC BZIP transcription factor NRF2 ⬇️

abstract published in 2006

Clinical benefits and pharmacology of scutellarin: a comprehensive review

artículo científico publicado en 2018

Common and distinct mechanisms of induced pulmonary fibrosis by particulate and soluble chemical fibrogenic agents

artículo científico publicado en 2015

Comparison of toxicity of benzene metabolite hydroquinone in hematopoietic stem cells derived from murine embryonic yolk sac and adult bone marrow

artículo científico publicado en 2013

Critical cysteine residues of Keap1 in suppression of Nrf2 basal activity and arsenic-sensing by regulating the ubiquitination-proteasomal degradation of Nrf2 protein ⬇️

abstract published in 2011

Critical cysteine residues of Kelch-like ECH-associated protein 1 in arsenic sensing and suppression of nuclear factor erythroid 2-related factor 2

artículo científico publicado en 2010

Critical role of Nrf2 cysteine residues in oxidant/eletrophile-sensing and signal transduction ⬇️

abstract published in 2010

Deltamethrin activates transcriptional factors NRF2 but does not increase GCSH protein expression in primary astrocytes with laser scanning confocal microscope ⬇️

conference abstract published in 2005

Deltamethrin-induced reactive oxygen species in PC12 cells and rats: Role of N-acetyl-L-cysteine

artículo científico publicado en 2006

Differential expression of cytochrome P450 genes associated with benzene-induced hematotoxicity ⬇️

conference abstract published in 2007

Disruption of Nrf2 synergizes with high glucose to cause heightened myocardial oxidative stress and severe cardiomyopathy in diabetic mice

artículo científico publicado en 2013

Drug-metabolizing enzymes: a group of promiscuous catalysts ⬇️

book or book chapter published in 2014

Editorial: immune mechanisms in the pathologic response to particles, fibers, and nanomaterials

publication published in 2021

Effect of deltamethrin on gene expression of both gamma-glutamylcysteine synthetase and NRF2 in brain tissue ⬇️

conference abstract published in 2005

Elevated expression of CYP4F3 associated with occupational benzene-induced hepatotoxicity and induction of CYP4F3 by benzene metabolites in HL60 cells ⬇️

conference abstract published in 2008

Essential role of Nrf2 in protection against ovarian follicle loss induced by 4-vinycyclohexene and 4-vinylcyclohexene diepoxide in mice ⬇️

abstract published in 2004

Essential role of Nrf2 in protection against ovarian follicle loss induced by 4-vinylcyclohexene and 4-vinylcyclohexene diepoxide in mice ⬇️

conference abstract published in May 2004

Essential role of Nrf2 in protection against ovarian follicle loss induced by 4-vinylcyclohexene and 4-vinylcyclohexene diepoxide in mice ⬇️

conference abstract published in 2004

Function and signal transduction of Nrf2 from a metal's perspective ⬇️

abstract published in 2008

Gene expression in benzene-exposed workers by microarray analysis of peripheral mononuclear blood cells: induction and silencing of CYP4F3A and regulation of DNA-dependent protein kinase catalytic subunit in DNA double strand break repair

artículo científico publicado en 2010

Identification and characterization of TIG1: a novel TCDD-inducible gene ⬇️

abstract published in 2000

Identification of critical cysteine residues of Keap1 in arsenic-sensing and suppression of Nrf2 ⬇️

abstract published in 2010

Impact of AH receptor degradation on gene transcription ⬇️

abstract published in 2002

In vivo activation and pro-fibrotic function of NF-kB in fibroblastic cells during pulmonary inflammation and fibrosis induced by carbon nanotubes

journal article published in 2019

In vivo activation of a T helper 2-driven innate immune response in lung fibrosis induced by multi-walled carbon nanotubes

artículo científico publicado en 2016

Induction and superinduction of 2,3,7,8-tetrachlorodibenzo-rho-dioxin-inducible poly(ADP-ribose) polymerase: role of the aryl hydrocarbon receptor/aryl hydrocarbon receptor nuclear translocator transcription activation domains and a labile transcrip

artículo científico publicado en 2002

Induction of ALOX5 during polarization of M1 macrophages by multi-walled carbon nanotubes

abstract published in 2022

Induction of CYP1A1. The AhR/DRE paradigm: transcription, receptor regulation, and expanding biological roles

artículo científico publicado en 2001

Induction of CYP4F3 by benzene metabolites in human white blood cells in vivo, in human promyelocytic leukemic cell lines, and ex vivo in human blood neutrophils

artículo científico publicado en 2008

Induction of CYP4F3 in white blood cells from benzene-poisoning patients and human HL60 cells

conference proceedings item published in 2008

Induction of NAD(P)H:quinone oxidoreductase: interplay between Ah receptor and Nrf2 ⬇️

abstract published in 2012

Induction of metallothionein I by arsenic via metal-activated transcription factor 1. Critical role of c-terminal cysteine residues in arsenic sensing

artículo científico publicado en 2009

Induction of metallothionein I by phenolic antioxidants requires metal-activated transcription factor 1 (MTF-1) and zinc ⬇️

abstract published in 2004

Induction of murine NAD(P)H:quinone oxidoreductase by 2,3,7,8- tetrachlorodibenzo-p-dioxin requires the CNC basic leucine zipper transcription factor NRF2. Cross-interaction between AHR and NRF2 signal transduction ⬇️

conference abstract published in 2004

Induction of thioredoxin-interacting protein and role in NLRP3 activation by carbon nanotubes in macrophages

abstract published in 2023

Induction of transcription by occupational heavy metals through the metal-activated transcription factor 1 is regulated by a labile repressor. Superinduction of metallothionein 1 by cyclohexmide ⬇️

conference abstract published in 2006

Inflammation and rapid-onset fibrosis in mouse lungs induced by multi-walled carbon nanotubes ⬇️

abstract published in 2014

Influence of light on aryl hydrocarbon receptor signaling and consequences in drug metabolism, physiology and disease ⬇️

artículo científico publicado el 2 de septiembre de 2011

Inhibition of DNA-dependent protein kinase catalytic subunit by small molecule inhibitor NU7026 sensitizes human leukemic K562 cells to benzene metabolite-induced apoptosis

artículo científico publicado en 2013

Inhibition of LPS-induced TNF-x expression by phenolic antioxidants ⬇️

abstract published in 2001

Inhibition of TNFalpha promoter/enhancer activity by phenolic antioxidants ⬇️

abstract published in 2002

Inhibition of nuclear factor kB by phenolic antioxidants: interplay between antioxidant signaling and inflammatory cytokine expression ⬇️

artículo científico publicado en 2003

Inhibition of nuclear factor kappa B by phenolic antioxidants: interplay between antioxidant signaling and inflammatory cytokine expression ⬇️

abstract published in 2004

Inhibition of paraquat-induced oxidative stress, proinflammatory cytokine expression, and fibroblast-tomyofibroblast transformation by resveratrol via the Nrf2 pathway ⬇️

abstract published in 2012

Integration of inflammation, fibrosis, and cancer induced by carbon nanotubes

artículo científico publicado en 2019

Integrins: form and role in myofibroblast differentiation and function ⬇️

chapter published in 2016

Interaction of Ah receptor with phenolic antioxidant signal transduction ⬇️

abstract published in 2002

Interactions of the AH receptor and oxidative signaling

artículo científico publicado en 2001

Macrophage polarization and activation at the interface of multi-walled carbon nanotube-induced pulmonary inflammation and fibrosis

artículo científico publicado en 2018

Metal sensing by MTF1 through its carboxyl-terminal cysteine residues ⬇️

abstract published in 2011

Molecular activation of NLRP3 inflammasome by particles and crystals: a continuing challenge of immunology and toxicology

artículo científico publicado en 2023

Molecular basis of electrophilic and oxidative defense: promises and perils of Nrf2

artículo científico publicado en 2012

Multi-walled carbon nanotube-induced lung inflammation and fibrosis ⬇️

abstract published in 2015

Multi-walled carbon nanotubes activate macrophages and NF-KB signaling to elicit inflammatory and fibrotic responses in mouse lungs ⬇️

abstract published in 2015

Multi-walled carbon nanotubes induce arachidonate 5-lipoxygenase expression and enhance the polarization and function of M1 macrophages in vitro

journal article published in 2023

Multi-walled carbon nanotubes induce arachidonate 5-lipoxygenase expression and enhance the polarization and function of M1 macrophages in vitro (dataset) ⬇️

research dataset published in 2023

Multi-walled carbon nanotubes induce proinflammatory cytokine expression by activating NF-kB signaling in mouse lungs ⬇️

abstract published in 2014

Multi-walled carbon nanotubes stimulate arachidonate 5-lipoxygenase-dependent M1 polarization of macrophages to promote proinflammatory response in vitro

abstract published in 2023

Multi-walled carbon nanotubes trigger and amplify Th2-type immune responses in mouse lungs ⬇️

abstract published in 2016

Multiorgan autoimmune inflammation, enhanced lymphoproliferation, and impaired homeostasis of reactive oxygen species in mice lacking the antioxidant-activated transcription factor Nrf2

artículo científico publicado en 2006

Multiwalled Carbon Nanotubes Induce a Fibrogenic Response by Stimulating Reactive Oxygen Species Production, Activating NF-κB Signaling, and Promoting Fibroblast-to-Myofibroblast Transformation ⬇️

artículo científico publicado el 22 de noviembre de 2011

Multiwalled carbon nanotubes damage the mitochondria to increase reactive oxygen radical production, activate NF-kB signaling to induce inflammatory cytokines, & stimulate transforming growth factor β1 & platelet-derived growth factor expression ... ⬇️

abstract published in 2013

Myofibroblasts and lung fibrosis induced by carbon nanotube exposure

artículo científico publicado en 2016

Myofibroblasts in cancer and fibrosis: two sides of the same coin? ⬇️

chapter published in 2016

NRF2 cysteine residues are critical for oxidant/electrophile-sensing, Kelch-like ECH-associated protein-1-dependent ubiquitination-proteasomal degradation, and transcription activation

artículo científico publicado en 2009

NRF2, an antioxidant activated CNC BZIP transcription factor: mechanism of action and role in autoimmune function ⬇️

abstract published in 2004

Nrf2 is critical in defense against high glucose-induced oxidative damage in cardiomyocytes

artículo científico publicado en 2009

Origins of individual variability in P4501A induction

artículo científico publicado en 2003

Osteopontin enhances multi-walled carbon nanotube-triggered lung fibrosis by promoting TGF-β1 activation and myofibroblast differentiation

artículo científico publicado en 2017

Overview of AHR functional domains and the classical AHR signaling pathway: induction of drug-metabolizing enzymes

chapter published in 2011

Pathologic and molecular profiling of rapid-onset fibrosis and inflammation induced by multi-walled carbon nanotubes

artículo científico publicado en 2014

Pharmacogenetics, Pharmacogenomics, and Individualized Medicine ⬇️

artículo científico publicado el 24 de marzo de 2011

Pharmacogenomics and individualized medicine ⬇️

chapter published in 2012

Pharmacological inhibition of the NLRP3 inflammasome: structure, molecular activation, and inhibitor-NLRP3 interaction

journal article published in 2023

Phosphorylation of Nrf2 in the transcription activation domain by casein kinase 2 (CK2) is critical for the nuclear translocation and transcription activation function of Nrf2 ⬇️

conference abstract published in 2007

Phosphorylation of Nrf2 in the transcription activation domain by casein kinase 2 (CK2) is critical for the nuclear translocation and transcription activation function of Nrf2 in IMR-32 neuroblastoma cells

artículo científico publicado en 2008

Polarization of immune cells in the pathologic response to inhaled particulates

artículo científico publicado en 2020

Protection against Chromium (VI)-induced oxidative stress and apoptosis by Nrf2. Recruiting Nrf2 into the nucleus and disrupting the nuclear Nrf2/Keap1 association

artículo científico publicado en 2007

Protection against Chromium (VI)-induced oxidative stress and apoptosis by Nrf2. Recruiting Nrf2 into the nucleus and disrupting the nuclear Nrf2/Keap1 association by toxic metal ⬇️

conference abstract published in 2007

Protection against chromium (VI)-induced oxidative stress and apoptosis by Nrf2 ⬇️

abstract published in 2010

Pulmonary inflammatory and fibrotic responses to carbon nanotube exposure in mice ⬇️

abstract published in 2015

Redox regulation by Nrf2: gatekeeping for the basal and diabetes-induced expression of thioredoxin interacting protein

artículo científico publicado en 2012

Regulation of TCDD-induced degradation of Ah receptor by cycloheximide

conference proceedings item published in 2000

Regulation of pancreatic islet beta cell functions by Nrf2 in vivo and in vitro

abstract published in 2013

Resolution of pulmonary inflammation induced by carbon nanotubes and fullerenes in mice: role of macrophage polarization

artículo científico publicado en 2020

Resveratrol inhibits paraquat-induced oxidative stress and fibrogenic response by activating the Nrf2 pathway

artículo científico publicado en 2012

Role of Nrf2 in oxidative stress and toxicity

artículo científico publicado en 2013

Single-walled carbon nanotubes induce fibrogenic effect by disturbing mitochondrial oxidative stress and activating NF-kB signaling

artículo científico publicado en 2012

Stem Cell and Benzene-Induced Malignancy and Hematotoxicity ⬇️

artículo científico publicado el 24 de mayo de 2012

Superinduction of CYP1A1 gene expression. Regulation of 2,3,7,8- tetrachlorodibenzo-p-dioxin-induced degradation of Ah receptor by cycloheximide ⬇️

artículo científico publicado en 2000

Superinduction of metallothionein I by inhibition of protein synthesis: role of a labile repressor in MTF-1 mediated gene transcription

artículo científico publicado en 2006

Suppression of basal and carbon nanotube-induced oxidative stress, inflammation and fibrosis in mouse lungs by Nrf2

artículo científico publicado en 2015

Suppression of basal and multi-walled carbon nanotube-induced lung inflammation and fibrosis by Nrf2 ⬇️

abstract published in 2016

TCDD-induced degradation of Ah receptor by the ubiquitin-proteasome pathway

conference abstract published in 2000

TCDD-inducible poly (ADP-ribose) polmerase: a novel response to 2,3,7,8-tetrachlorodibenzo-p-dioxin

artículo científico publicado en 2001

TIMP1 promotes multi-walled carbon nanotube-induced lung fibrosis by stimulating fibroblast activation and proliferation

artículo científico publicado en 2016

Th2-driven innate immune responses in the development of lung fibrosis induced by multi-walled carbon nanotubes ⬇️

abstract published in 2016

The antioxidant-activated transcription factor Nrf2 controls both the ARE- and DRE-dependent induction of NAD(P)H:quinone oxidoreductase: cross-interaction between Nrf2 and AHR signal transduction ⬇️

conference abstract published in 2003

The aryl hydrocarbon receptor interacts with nuclear factor erythroid 2-related factor 2 to mediate induction of NAD(P)H:quinoneoxidoreductase 1 by 2,3,7,8-tetrachlorodibenzo-p-dioxin

artículo científico publicado en 2013

The carboxyl-terminal cysteine residues of MTF1 are critical for arsenic sensing and induction of MT1 ⬇️

abstract published in 2010

The challenges of dealing with promiscuous drug-metabolizing enzymes, receptors and transporters

artículo científico publicado en 2008

The pesticide deltamethrin increases free radical production and promotes nuclear translocation of the stress response transcription factor Nrf2 in rat brain

artículo científico publicado en 2011

Time course of gene expression of gamma-glutamylcysteine synthetase subunit and NRF2 in brain tissues of rats treated with deltamethrin ⬇️

conference abstract published in 2005

Transcriptional regulation of TIG1, a novel TCDD-inducible gene, by the aryl hydrocarbon receptor ⬇️

abstract published in 2001

Transcriptional responses to oxidative stress: pathological and toxicological implications

artículo científico publicado en 2010

Type 2 immune mechanisms in carbon nanotube-induced lung fibrosis

artículo científico publicado en 2018

Tyrosine hydroxylase as a target for deltamethrin in the nigrostriatal dopaminergic pathway ⬇️

artículo científico publicado en 2006

Vacuolar leukoencephalopathy with widespread astrogliosis in mice lacking transcription factor Nrf2

artículo científico publicado en 2007

Xenobiotic-activated receptors: from transcription to drug metabolism to disease

artículo científico publicado en 2008

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