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A Review of Recent Patents (2016-2019) on Plant Food Supplements with Potential Application in the Treatment of Neurodegenerative and Metabolic Disorders

scientific article published on 13 March 2020

An innovative approach for the treatment of Alzheimer's disease: the role of peroxisome proliferator-activated receptors and their ligands in development of alternative therapeutic interventions

article

An update about the crucial role of stereochemistry on the effects of Peroxisome Proliferator-Activated Receptor ligands

artículo científico publicado en 2019

Beyond the Canonical Endocannabinoid System. A Screening of PPAR Ligands as FAAH Inhibitors

artículo científico publicado en 2020

Bone-Seeking Matrix Metalloproteinase Inhibitors for the Treatment of Skeletal Malignancy

scientific article published on 01 June 2020

Catechol-based matrix metalloproteinase inhibitors with additional antioxidative activity.

artículo científico publicado en 2016

Chiral phenoxyacetic acid analogues inhibit colon cancer cell proliferation acting as PPARγ partial agonists

scientific article published on 01 April 2019

Combining fatty acid amide hydrolase (FAAH) inhibition with peroxisome proliferator-activated receptor (PPAR) activation: a new potential multi-target therapeutic strategy for the treatment of Alzheimer's disease

artículo científico publicado en 2020

Deep Eutectic Solvents as Effective Reaction Media for the Synthesis of 2-Hydroxyphenylbenzimidazole-based Scaffolds en Route to Donepezil-Like Compounds

artículo científico publicado en 2020

Deep Eutectic Solvents as Novel and Effective Extraction Media for Quantitative Determination of Ochratoxin A in Wheat and Derived Products.

artículo científico publicado en 2017

Design, Synthesis, and In Vitro Evaluation of Hydroxybenzimidazole-Donepezil Analogues as Multitarget-Directed Ligands for the Treatment of Alzheimer's Disease

artículo científico publicado en 2020

Design, synthesis and biological evaluation of a class of bioisosteric oximes of the novel dual peroxisome proliferator-activated receptor α/γ ligand LT175.

artículo científico publicado en 2014

Donepezil structure-based hybrids as potential multifunctional anti-Alzheimer's drug candidates

scientific article published on 01 December 2018

Effect of gaseous ozone treatments on DON, microbial contaminants and technological parameters of wheat and semolina

artículo científico publicado en 2017

Effects of temperature and water activity change on ecophysiology of ochratoxigenic Aspergillus carbonarius in field-simulating conditions

artículo científico publicado en 2019

Food Industry Byproducts as Starting Material for Innovative, Green Feed Formulation: A Sustainable Alternative for Poultry Feeding

artículo científico publicado en 2022

Food coloring agents and plant food supplements derived from Vitis vinifera: a new source of human exposure to ochratoxin A.

artículo científico publicado en 2015

Frontal affinity chromatography with MS detection of the ligand binding domain of PPARγ receptor: Ligand affinity screening and stereoselective ligand–macromolecule interaction

artículo científico publicado el 19 de octubre de 2011

Heterocyclic compounds as key structures for the interaction with old and new targets in Alzheimer's disease therapy.

artículo científico publicado en 2017

Hydroxypyridinone derivatives: a fascinating class of chelators with therapeutic applications - an update

artículo científico publicado en 2017

Identification of the First PPARα/γ Dual Agonist Able To Bind to Canonical and Alternative Sites of PPARγ and To Inhibit Its Cdk5-Mediated Phosphorylation

scientific article published on 18 September 2018

Molecular determinants for nuclear receptors selectivity: chemometric analysis, dockings and site-directed mutagenesis of dual peroxisome proliferator-activated receptors α/γ agonists.

artículo científico publicado en 2013

Natural Compounds for the Prevention and Treatment of Cardiovascular and Neurodegenerative Diseases

artículo científico publicado en 2020

Natural Scaffolds with Multi-Target Activity for the Potential Treatment of Alzheimer's Disease

artículo científico publicado en 2018

New 2-(aryloxy)-3-phenylpropanoic acids as peroxisome proliferator-activated receptor α/γ dual agonists able to upregulate mitochondrial carnitine shuttle system gene expression

artículo científico publicado en 2013

New Approaches to Cancer Therapy: Combining Fatty Acid Amide Hydrolase (FAAH) Inhibition with Peroxisome Proliferator-Activated Receptors (PPARs) Activation

artículo científico publicado en 2019

New approaches for prevention and treatment of Alzheimer's disease: a fascinating challenge

artículo científico publicado en 2017

New diphenylmethane derivatives as peroxisome proliferator-activated receptor alpha/gamma dual agonists endowed with anti-proliferative effects and mitochondrial activity.

artículo científico publicado en 2016

Novel tacrine-benzofuran hybrids as potential multi-target drug candidates for the treatment of Alzheimer's Disease

scientific article published on 01 December 2020

Occurrence of patulin in conventional and organic fruit products in Italy and subsequent exposure assessment.

artículo científico publicado en 2005

Open tubular columns containing the immobilized ligand binding domain of peroxisome proliferator-activated receptors α and γ for dual agonists characterization by frontal affinity chromatography with mass spectrometry detection.

artículo científico publicado en 2013

Plant Food Supplements with Antioxidant Properties for the Treatment of Chronic and Neurodegenerative Diseases: Benefits or Risks?

artículo científico publicado en 2016

Reduction of Aflatoxins in Apricot Kernels by Electronic and Manual Color Sorting

artículo científico publicado en 2016

Synthesis, biological evaluation and molecular investigation of fluorinated peroxisome proliferator-activated receptors α/γ dual agonists

artículo científico publicado en 2012

Synthesis, biological evaluation, and molecular modeling investigation of chiral 2-(4-chloro-phenoxy)-3-phenyl-propanoic acid derivatives with PPARalpha and PPARgamma agonist activity.

artículo científico publicado en 2008

Synthesis, biological evaluation, and molecular modeling investigation of chiral phenoxyacetic acid analogues with PPARalpha and PPARgamma agonist activity.

artículo científico publicado en 2007

Virtual screening identification and chemical optimization of substituted 2-arylbenzimidazoles as new non-zinc-binding MMP-2 inhibitors

artículo científico publicado en 2019