Lista de obras -

A gene-centric study of common carotid artery remodelling

artículo científico publicado en 2012

A genetic instrument for Mendelian randomization of fibrinogen.

artículo científico publicado en 2012

A genetic risk score is associated with statin-induced low-density lipoprotein cholesterol lowering

artículo científico publicado en 2016

A metabolic profile of all-cause mortality risk identified in an observational study of 44,168 individuals

scientific article published on 20 August 2019

APOE, CETP and LPL genes show strong association with lipid levels in Greek children

artículo científico publicado en 2009

APOE/C1/C4/C2 gene cluster genotypes, haplotypes and lipid levels in prospective coronary heart disease risk among UK healthy men

artículo científico publicado en 2010

Adult height, coronary heart disease and stroke: a multi-locus Mendelian randomization meta-analysis

artículo científico publicado en 2016

Angiotensin-converting enzyme genotype and successful ascent to extreme high altitude

scientific article published on 01 January 2007

Application of statistical and functional methodologies for the investigation of genetic determinants of coronary heart disease biomarkers: lipoprotein lipase genotype and plasma triglycerides as an exemplar.

artículo científico publicado en 2010

Assessment of the clinical utility of adding common single nucleotide polymorphism genetic scores to classical risk factor algorithms in coronary heart disease risk prediction in UK men.

artículo científico publicado en 2017

Blood pressure loci identified with a gene-centric array

artículo científico publicado en 2011

Candidate gene association studies in abdominal aortic aneurysm disease: a review and meta-analysis.

artículo científico publicado en 2007

Causal relevance of blood lipid fractions in the development of carotid atherosclerosis: Mendelian randomization analysis

artículo científico publicado en 2012

Clinical Utility of a Coronary Heart Disease Risk Prediction Gene Score in UK Healthy Middle Aged Men and in the Pakistani Population

artículo científico publicado en 2015

Comparative analysis of genome-wide association studies signals for lipids, diabetes, and coronary heart disease: Cardiovascular Biomarker Genetics Collaboration

artículo científico publicado en 2011

Correction: Population Genomics of Cardiometabolic Traits: Design of the University College London-London School of Hygiene and Tropical Medicine-Edinburgh-Bristol (UCLEB) Consortium.

artículo científico publicado en 2013

Cystatin C and Cardiovascular Disease: A Mendelian Randomization Study

artículo científico publicado en 2016

Discovery and replication of SNP-SNP interactions for quantitative lipid traits in over 60,000 individuals

artículo científico publicado en 2017

Discovery of rare variants associated with blood pressure regulation through meta-analysis of 1.3 million individuals

artículo científico publicado en 2020

ERRATUM: Meta-analysis of Dense Genecentric Association Studies Reveals Common and Uncommon Variants Associated with Height

article by Matthew B. Lanktree et al published June 2012 in American Journal of Human Genetics

FVII, FVIIa, and downstream markers of extrinsic pathway activation differ by EPCR Ser219Gly variant in healthy men

artículo científico publicado en 2009

Four genetic loci influencing electrocardiographic indices of left ventricular hypertrophy

artículo científico publicado en 2011

Gene-centric association signals for haemostasis and thrombosis traits identified with the HumanCVD BeadChip

artículo científico publicado en 2013

Gene-centric association signals for lipids and apolipoproteins identified via the HumanCVD BeadChip

artículo científico publicado en 2009

Gene-targeted analysis of copy number variants identifies 3 novel associations with coronary heart disease traits.

artículo científico publicado en 2012

Genetic meta-analysis of 15,901 African Americans identifies variation in EXOC3L1 is associated with HDL concentration.

artículo científico publicado en 2015

Genetic variants associated with Von Willebrand factor levels in healthy men and women identified using the HumanCVD BeadChip

artículo científico publicado en 2011

Genome-wide association analysis identifies novel blood pressure loci and offers biological insights into cardiovascular risk.

artículo científico publicado en 2017

HMG-coenzyme A reductase inhibition, type 2 diabetes, and bodyweight: evidence from genetic analysis and randomised trials

artículo científico publicado en 2014

Haplotype and genotype effects of the F7 gene on circulating factor VII, coagulation activation markers and incident coronary heart disease in UK men.

artículo científico publicado en 2010

How close are we to implementing a genetic risk score for coronary heart disease?

artículo científico publicado en 2017

IRS1 gene variants, dysglycaemic metabolic changes and type-2 diabetes risk.

artículo científico publicado en 2011

Identifying gene-gene interactions that are highly associated with Body Mass Index using Quantitative Multifactor Dimensionality Reduction (QMDR)

artículo científico publicado en 2015

Influence of common genetic variation on blood lipid levels, cardiovascular risk, and coronary events in two British prospective cohort studies

artículo científico publicado en 2012

Integration of genetics into a systems model of electrocardiographic traits using HumanCVD BeadChip

artículo científico publicado en 2012

Large-scale gene-centric meta-analysis across 32 studies identifies multiple lipid loci

artículo científico publicado en 2012

Large-scale gene-centric meta-analysis across 39 studies identifies type 2 diabetes loci

artículo científico publicado en 2012

Marginal role for 53 common genetic variants in cardiovascular disease prediction

artículo científico publicado en 2016

Mechanistic insights from combining genomics with metabolomics

artículo científico publicado en 2017

Mendelian randomization of blood lipids for coronary heart disease

artículo científico publicado en 2014

Meta-analysis identifies common and rare variants influencing blood pressure and overlapping with metabolic trait loci

artículo científico publicado en 2016

Meta-analysis of Dense Genecentric Association Studies Reveals Common and Uncommon Variants Associated with Height

artículo científico publicado en 2010

Metabolic Characterization of a Rare Genetic Variation Within APOC3 and Its Lipoprotein Lipase-Independent Effects

artículo científico publicado en 2016

Metabolic signatures of birth weight in 18288 adolescents and adults

artículo científico publicado en 2016

Metabolic signatures of birthweight in 18 288 adolescents and adults.

artículo científico publicado en 2016

Networks in Coronary Heart Disease Genetics As a Step towards Systems Epidemiology

artículo científico publicado en 2015

New Blood Pressure-Associated Loci Identified in Meta-Analyses of 475 000 Individuals

artículo científico publicado en 2017

PROTEIN-CODING VARIANTS IMPLICATE NOVEL GENES RELATED TO LIPID HOMEOSTASIS CONTRIBUTING TO BODY FAT DISTRIBUTION

article

Plasma urate concentration and risk of coronary heart disease: a Mendelian randomisation analysis

artículo científico publicado en 2016

Population genomics of cardiometabolic traits: design of the University College London-London School of Hygiene and Tropical Medicine-Edinburgh-Bristol (UCLEB) Consortium

artículo científico publicado en 2013

Post-GWAS methodologies for localisation of functional non-coding variants: ANGPTL3.

artículo científico publicado en 2015

Progress in genetic association studies of plasma lipids.

artículo científico publicado en 2013

Protein-altering variants associated with body mass index implicate pathways that control energy intake and expenditure in obesity

artículo científico publicado en 2017

Protein-coding variants implicate novel genes related to lipid homeostasis contributing to body-fat distribution

article

Publisher Correction: Protein-altering variants associated with body mass index implicate pathways that control energy intake and expenditure in obesity

artículo científico publicado en 2018

Publisher Correction: Protein-altering variants associated with body mass index implicate pathways that control energy intake and expenditure in obesity

artículo científico publicado en 2018

Publisher Correction: Protein-altering variants associated with body mass index implicate pathways that control energy intake and expenditure in obesity

artículo científico publicado en 2019

Rare and low-frequency coding variants alter human adult height

artículo científico publicado en 2017

Replication and Characterization of Association between ABO SNPs and Red Blood Cell Traits by Meta-Analysis in Europeans

artículo científico publicado en 2016

Selection on alleles affecting human longevity and late-life disease: the example of apolipoprotein E.

artículo científico publicado en 2010

Sixty-five common genetic variants and prediction of type 2 diabetes

artículo científico publicado en 2014

Systems epidemiology of metabolomics measures reveals new relationships between lipoproteins and other small molecules

artículo científico publicado en 2021

Tagging SNP haplotype analysis of the secretory PLA2-V gene, PLA2G5 , shows strong association with LDL and oxLDL levels, suggesting functional distinction from sPLA2-IIA: results from the UDACS study

article

The genetics of blood pressure regulation and its target organs from association studies in 342,415 individuals

artículo científico publicado en 2016

The interleukin-6 receptor as a target for prevention of coronary heart disease: a mendelian randomisation analysis

artículo científico publicado en 2012

The use of Meta-Analysis Risk Estimates for Candidate Genes in Combination to Predict Coronary Heart Disease Risk

article

The use of genetic information in the prediction of Type 2 diabetes

artículo científico publicado en 2015

Trade-off mediated effects on the genetics of human survival caused by increasingly benign living conditions

artículo científico publicado en 2006

Trans-ancestry meta-analyses identify rare and common variants associated with blood pressure and hypertension

artículo científico publicado en 2016

Variant rs10911021 that associates with coronary heart disease in type 2 diabetes, is associated with lower concentrations of circulating HDL cholesterol and large HDL particles but not with amino acids

artículo científico publicado en 2016

Lista de obras de

A gene-centric study of common carotid artery remodelling

A genetic instrument for Mendelian randomization of fibrinogen.

A genetic risk score is associated with statin-induced low-density lipoprotein cholesterol lowering

A metabolic profile of all-cause mortality risk identified in an observational study of 44,168 individuals

APOE, CETP and LPL genes show strong association with lipid levels in Greek children

APOE/C1/C4/C2 gene cluster genotypes, haplotypes and lipid levels in prospective coronary heart disease risk among UK healthy men

Adult height, coronary heart disease and stroke: a multi-locus Mendelian randomization meta-analysis

Angiotensin-converting enzyme genotype and successful ascent to extreme high altitude

Application of statistical and functional methodologies for the investigation of genetic determinants of coronary heart disease biomarkers: lipoprotein lipase genotype and plasma triglycerides as an exemplar.

Assessment of the clinical utility of adding common single nucleotide polymorphism genetic scores to classical risk factor algorithms in coronary heart disease risk prediction in UK men.

Blood pressure loci identified with a gene-centric array

Candidate gene association studies in abdominal aortic aneurysm disease: a review and meta-analysis.

Causal relevance of blood lipid fractions in the development of carotid atherosclerosis: Mendelian randomization analysis

Clinical Utility of a Coronary Heart Disease Risk Prediction Gene Score in UK Healthy Middle Aged Men and in the Pakistani Population

Comparative analysis of genome-wide association studies signals for lipids, diabetes, and coronary heart disease: Cardiovascular Biomarker Genetics Collaboration

Correction: Population Genomics of Cardiometabolic Traits: Design of the University College London-London School of Hygiene and Tropical Medicine-Edinburgh-Bristol (UCLEB) Consortium.

Cystatin C and Cardiovascular Disease: A Mendelian Randomization Study

Discovery and replication of SNP-SNP interactions for quantitative lipid traits in over 60,000 individuals

Discovery of rare variants associated with blood pressure regulation through meta-analysis of 1.3 million individuals

ERRATUM: Meta-analysis of Dense Genecentric Association Studies Reveals Common and Uncommon Variants Associated with Height

FVII, FVIIa, and downstream markers of extrinsic pathway activation differ by EPCR Ser219Gly variant in healthy men

Four genetic loci influencing electrocardiographic indices of left ventricular hypertrophy

Gene-centric association signals for haemostasis and thrombosis traits identified with the HumanCVD BeadChip

Gene-centric association signals for lipids and apolipoproteins identified via the HumanCVD BeadChip

Gene-targeted analysis of copy number variants identifies 3 novel associations with coronary heart disease traits.

Genetic meta-analysis of 15,901 African Americans identifies variation in EXOC3L1 is associated with HDL concentration.

Genetic variants associated with Von Willebrand factor levels in healthy men and women identified using the HumanCVD BeadChip

Genome-wide association analysis identifies novel blood pressure loci and offers biological insights into cardiovascular risk.

HMG-coenzyme A reductase inhibition, type 2 diabetes, and bodyweight: evidence from genetic analysis and randomised trials

Haplotype and genotype effects of the F7 gene on circulating factor VII, coagulation activation markers and incident coronary heart disease in UK men.

How close are we to implementing a genetic risk score for coronary heart disease?

IRS1 gene variants, dysglycaemic metabolic changes and type-2 diabetes risk.

Identifying gene-gene interactions that are highly associated with Body Mass Index using Quantitative Multifactor Dimensionality Reduction (QMDR)

Influence of common genetic variation on blood lipid levels, cardiovascular risk, and coronary events in two British prospective cohort studies

Integration of genetics into a systems model of electrocardiographic traits using HumanCVD BeadChip

Large-scale gene-centric meta-analysis across 32 studies identifies multiple lipid loci

Large-scale gene-centric meta-analysis across 39 studies identifies type 2 diabetes loci

Marginal role for 53 common genetic variants in cardiovascular disease prediction

Mechanistic insights from combining genomics with metabolomics

Mendelian randomization of blood lipids for coronary heart disease

Meta-analysis identifies common and rare variants influencing blood pressure and overlapping with metabolic trait loci

Meta-analysis of Dense Genecentric Association Studies Reveals Common and Uncommon Variants Associated with Height

Metabolic Characterization of a Rare Genetic Variation Within APOC3 and Its Lipoprotein Lipase-Independent Effects

Metabolic signatures of birth weight in 18288 adolescents and adults

Metabolic signatures of birthweight in 18 288 adolescents and adults.

Networks in Coronary Heart Disease Genetics As a Step towards Systems Epidemiology

New Blood Pressure-Associated Loci Identified in Meta-Analyses of 475 000 Individuals

PROTEIN-CODING VARIANTS IMPLICATE NOVEL GENES RELATED TO LIPID HOMEOSTASIS CONTRIBUTING TO BODY FAT DISTRIBUTION

Plasma urate concentration and risk of coronary heart disease: a Mendelian randomisation analysis

Population genomics of cardiometabolic traits: design of the University College London-London School of Hygiene and Tropical Medicine-Edinburgh-Bristol (UCLEB) Consortium

Post-GWAS methodologies for localisation of functional non-coding variants: ANGPTL3.

Progress in genetic association studies of plasma lipids.

Protein-altering variants associated with body mass index implicate pathways that control energy intake and expenditure in obesity

Protein-coding variants implicate novel genes related to lipid homeostasis contributing to body-fat distribution

Publisher Correction: Protein-altering variants associated with body mass index implicate pathways that control energy intake and expenditure in obesity

Publisher Correction: Protein-altering variants associated with body mass index implicate pathways that control energy intake and expenditure in obesity

Publisher Correction: Protein-altering variants associated with body mass index implicate pathways that control energy intake and expenditure in obesity

Rare and low-frequency coding variants alter human adult height

Replication and Characterization of Association between ABO SNPs and Red Blood Cell Traits by Meta-Analysis in Europeans

Selection on alleles affecting human longevity and late-life disease: the example of apolipoprotein E.

Sixty-five common genetic variants and prediction of type 2 diabetes

Systems epidemiology of metabolomics measures reveals new relationships between lipoproteins and other small molecules

Tagging SNP haplotype analysis of the secretory PLA2-V gene, PLA2G5 , shows strong association with LDL and oxLDL levels, suggesting functional distinction from sPLA2-IIA: results from the UDACS study

The genetics of blood pressure regulation and its target organs from association studies in 342,415 individuals

The interleukin-6 receptor as a target for prevention of coronary heart disease: a mendelian randomisation analysis

The use of Meta-Analysis Risk Estimates for Candidate Genes in Combination to Predict Coronary Heart Disease Risk

The use of genetic information in the prediction of Type 2 diabetes

Trade-off mediated effects on the genetics of human survival caused by increasingly benign living conditions

Trans-ancestry meta-analyses identify rare and common variants associated with blood pressure and hypertension

Variant rs10911021 that associates with coronary heart disease in type 2 diabetes, is associated with lower concentrations of circulating HDL cholesterol and large HDL particles but not with amino acids