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Acute promyelocytic leukemias share cooperative mutations with other myeloid-leukemia subgroups

artículo científico

Acute promyelocytic leukemias share cooperative mutations with other myeloid-leukemia subgroups.

artículo científico publicado en 2013

Blastic plasmacytoid dendritic cell neoplasm: genomics mark epigenetic dysregulation as a primary therapeutic target

scientific article published on 31 October 2018

Cell cycle-dependent resolution of DNA double-strand breaks.

artículo científico publicado en 2015

Exploiting the tunability of stimulated emission depletion microscopy for super-resolution imaging of nuclear structures

artículo científico publicado en 2018

Genome-wide mapping of 8-oxo-7,8-dihydro-2'-deoxyguanosine reveals accumulation of oxidatively-generated damage at DNA replication origins within transcribed long genes of mammalian cells

article

Genome-wide mapping of human DNA-replication origins: levels of transcription at ORC1 sites regulate origin selection and replication timing.

artículo científico publicado en 2012

In Vivo Genetic Screens of Patient-Derived Tumors Revealed Unexpected Frailty of the Transformed Phenotype.

artículo científico publicado en 2016

In Vivo Functional Platform Targeting Patient-Derived Xenografts Identifies WDR5-Myc Association as a Critical Determinant of Pancreatic Cancer.

artículo científico publicado en 2016

Next-generation sequencing and DNA replication in human cells: the future has arrived.

artículo científico

Pathology tissue-chromatin immunoprecipitation, coupled with high-throughput sequencing, allows the epigenetic profiling of patient samples.

artículo científico publicado en 2010

Peak shape clustering reveals biological insights

artículo científico publicado en 2015

Polycomb complexes and the propagation of the methylation mark at the Drosophila ubx gene.

artículo científico publicado en 2006

Polycomb silencing blocks transcription initiation.

artículo científico publicado en 2004

Polycomb silencing mechanisms in Drosophila.

artículo científico publicado en 2004

Release of paused RNA polymerase II at specific loci favors DNA double-strand-break formation and promotes cancer translocations

artículo científico publicado en 2019

Sequence-specific double strand breaks trigger P-TEFb-dependent Rpb1-CTD hyperphosphorylation.

artículo científico publicado en 2013

p53 Loss in Breast Cancer Leads to Myc Activation, Increased Cell Plasticity, and Expression of a Mitotic Signature with Prognostic Value

artículo científico publicado en 2019