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11β-Hydroxysteroid dehydrogenase 1: translational and therapeutic aspects

artículo científico

5α-Reductase Type 2 Regulates Glucocorticoid Action and Metabolic Phenotype in Human Hepatocytes

artículo científico publicado en 2015

A novel selective 11beta-hydroxysteroid dehydrogenase type 1 inhibitor prevents human adipogenesis.

artículo científico publicado en 2008

AKR1D1 knockout mice develop a sex-dependent metabolic phenotype

artículo científico publicado en 2022

AKR1D1 regulates glucocorticoid availability and glucocorticoid receptor activation in human hepatoma cells

artículo científico publicado en 2019

Adipose tissue-specific androgen generation fuels an adverse metabolic phenotype in patients with polycystic ovary syndrome

Advanced non-alcoholic fatty liver disease and adipose tissue fibrosis in patients with Alström syndrome.

artículo científico publicado en 2016

Effect of insulin on AKR1C3 expression in female adipose tissue: in-vivo and in-vitro study of adipose androgen generation in polycystic ovary syndrome.

artículo científico publicado en 2015

Evidence for a shift to anaerobic metabolism in adipose tissue in efavirenz-containing regimens for HIV with different nucleoside backbones

scientific article published on 13 December 2011

Glucagon-like peptide 1 decreases lipotoxicity in non-alcoholic steatohepatitis.

artículo científico publicado en 2015

Glucocorticoids regulate AKR1D1 activity in human liver in vitro and in vivo

artículo científico publicado en 2020

Human and murine steroid 5β-reductases (AKR1D1 and AKR1D4): insights into the role of the catalytic glutamic acid

artículo científico publicado en 2019

Increased central adiposity and decreased subcutaneous adipose tissue 11β-hydroxysteroid dehydrogenase type 1 are associated with deterioration in glucose tolerance-A longitudinal cohort study

artículo científico publicado en 2019

No evidence for genetic association of interferon regulatory factor 1 in juvenile idiopathic arthritis

article

Short- and long-term glucocorticoid treatment enhances insulin signalling in human subcutaneous adipose tissue.

artículo científico publicado en 2011

The role of 11beta-hydroxysteroid dehydrogenase 1 in adipogenesis in thyroid-associated ophthalmopathy

artículo científico publicado en 2009

Tissue specific regulation of glucocorticoids in severe obesity and the response to significant weight loss following bariatric surgery (BARICORT).

artículo científico