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A pentapeptide signature motif plays a pivotal role in Leishmania DNA topoisomerase IB activity and camptothecin sensitivity

artículo científico publicado en 2012

Deletion study of DNA topoisomerase IB from Leishmania donovani: searching for a minimal functional heterodimer.

artículo científico publicado en 2007

Diamine and aminoalcohol derivatives active against Trypanosoma brucei

artículo científico publicado en 2011

Establishment of a structure-activity relationship of 1H-imidazo[4,5-c]quinoline-based kinase inhibitor NVP-BEZ235 as a lead for African sleeping sickness

artículo científico publicado en 2014

Evaluation of a class of isatinoids identified from a high-throughput screen of human kinase inhibitors as anti-Sleeping Sickness agents

artículo científico publicado en 2019

From Cells to Mice to Target: Characterization of NEU-1053 (SB-443342) and Its Analogues for Treatment of Human African Trypanosomiasis.

artículo científico publicado en 2017

Identification and characterization of hundreds of potent and selective inhibitors of Trypanosoma brucei growth from a kinase-targeted library screening campaign

artículo científico publicado en 2014

Novel 1,2-dihydroquinazolin-2-ones: Design, synthesis, and biological evaluation against Trypanosoma brucei

artículo científico

Target of rapamycin (TOR) kinase in Trypanosoma brucei: an extended family.

artículo científico publicado en 2013

The susceptibility of trypanosomatid pathogens to PI3/mTOR kinase inhibitors affords a new opportunity for drug repurposing

artículo científico publicado en 2011