Lista de obras -

A CRISPR-Cas9 screen identifies essential CTCF anchor sites for estrogen receptor-driven breast cancer cell proliferation

artículo científico publicado en 2019

A carrier-assisted ChIP-seq method for estrogen receptor-chromatin interactions from breast cancer core needle biopsy samples.

artículo científico publicado en 2013

A review of estrogen receptor/androgen receptor genomics in male breast cancer

artículo científico publicado en 2017

APOBEC3B-Mediated Cytidine Deamination Is Required for Estrogen Receptor Action in Breast Cancer

artículo científico publicado en 2015

Activation of endosomal dynein motors by stepwise assembly of Rab7-RILP-p150Glued, ORP1L, and the receptor betalll spectrin

artículo científico publicado en 2007

An Antiestrogenic Activity Score for tamoxifen and its metabolites is associated with breast cancer outcome.

artículo científico publicado en 2016

An androgen receptor switch underlies lineage infidelity in treatment-resistant prostate cancer

artículo científico publicado en 2021

Androgen receptor DNA binding and chromatin accessibility profiling in prostate cancer.

artículo científico publicado en 2015

Androgen receptor enhancer usage and the chromatin regulatory landscape in human prostate cancers

artículo científico publicado en 2019

Androgen receptor moonlighting in the prostate cancer microenvironment.

artículo científico publicado en 2018

Androgen receptor profiling predicts prostate cancer outcome

artículo científico publicado en 2015

Androgen receptor signalling in macrophages promotes TREM-1-mediated prostate cancer cell line migration and invasion

scientific article published on 09 September 2020

BRCA1-associated mammary tumorigenesis is dependent on estrogen rather than progesterone signaling

artículo científico publicado en 2018

CHD1 Loss Alters AR Binding at Lineage-Specific Enhancers and Modulates Distinct Transcriptional Programs to Drive Prostate Tumorigenesis

scientific article published on 01 May 2019

CHD1 Loss Alters AR Binding at Lineage-Specific Enhancers and Modulates Distinct Transcriptional Programs to Drive Prostate Tumorigenesis

artículo científico publicado en 2019

CUEDC1 is a primary target of ERα essential for the growth of breast cancer cells

scientific article published on 23 August 2018

Can predictive biomarkers in breast cancer guide adjuvant endocrine therapy?

artículo científico publicado en 2012

Characterizing steroid hormone receptor chromatin binding landscapes in male and female breast cancer.

artículo científico publicado en 2018

Chemical profiling of primary mesothelioma cultures defines subtypes with different expression profiles and clinical responses.

artículo científico publicado en 2017

Cholesterol sensor ORP1L contacts the ER protein VAP to control Rab7-RILP-p150 Glued and late endosome positioning

artículo científico publicado en 2009

Classification of anti-estrogens according to intramolecular FRET effects on phospho-mutants of estrogen receptor alpha.

artículo científico publicado en 2007

Co-regulated gene expression by oestrogen receptor α and liver receptor homolog-1 is a feature of the oestrogen response in breast cancer cells.

scientific article published on 17 September 2013

Cognitive effects of endocrine therapy for breast cancer: keep calm and carry on?

artículo científico

Comparative Cistromics Reveals Genomic Cross-talk between FOXA1 and ERα in Tamoxifen-Associated Endometrial Carcinomas.

artículo científico publicado en 2016

Complex formation and function of estrogen receptor α in transcription requires RIP140.

artículo científico publicado en 2014

Discovery of naturally occurring ESR1 mutations in breast cancer cell lines modelling endocrine resistance

artículo científico publicado en 2017

Dissecting the predictive value of MAPK/AKT/estrogen-receptor phosphorylation axis in primary breast cancer to treatment response for tamoxifen over exemestane: a Translational Report of the Intergroup Exemestane Study (IES)-PathIES

artículo científico publicado en 2019

Drug-Induced Epigenomic Plasticity Reprograms Circadian Rhythm Regulation to Drive Prostate Cancer toward Androgen Independence

artículo científico publicado en 2022

Drug-induced histone eviction from open chromatin contributes to the chemotherapeutic effects of doxorubicin

artículo científico publicado en 2013

Dual functions of SPOP and ERG dictate androgen therapy responses in prostate cancer

artículo científico publicado en 2021

ERα activity depends on interaction and target site corecruitment with phosphorylated CREB1

artículo científico publicado en 2018

Effects of Pharmacogenetics on the Pharmacokinetics and Pharmacodynamics of Tamoxifen

artículo científico publicado en 2015

Endogenous androgen receptor proteomic profiling reveals genomic subcomplex involved in prostate tumorigenesis

artículo científico publicado en 2017

Enzalutamide therapy for advanced prostate cancer: efficacy, resistance and beyond

artículo científico publicado en 2018

Estrogen receptor α wields treatment-specific enhancers between morphologically similar endometrial tumors.

artículo científico publicado en 2017

Estrogen receptor-positive breast cancer: a multidisciplinary challenge.

artículo científico publicado en 2011

Extensive androgen receptor enhancer heterogeneity in primary prostate cancers underlies transcriptional diversity and metastatic potential

scientific article published in 2022

FOXA1 levels are decreased in pleural breast cancer metastases after adjuvant endocrine therapy, and this is associated with poor outcome

artículo científico publicado en 2018

Frequent clonal relations between metastases and non-index prostate cancer lesions

article

Functional genetic screens for enhancer elements in the human genome using CRISPR-Cas9.

artículo científico publicado en 2016

GATA3 Truncating Mutations Promote Cistromic Re-Programming In Vitro, but Not Mammary Tumor Formation in Mice

scientific article published on 19 June 2019

Genome-wide epigenetic profiling of breast cancer tumors treated with aromatase inhibitors.

artículo científico publicado en 2014

Glucocorticoid receptor triggers a reversible drug-tolerant dormancy state with acquired therapeutic vulnerabilities in lung cancer

artículo científico publicado en 2021

Hallmarks of aromatase inhibitor drug resistance revealed by epigenetic profiling in breast cancer.

artículo científico publicado en 2013

IGF-1R pathway activation as putative biomarker for linsitinib therapy to revert tamoxifen resistance in ER-positive breast cancer

scientific article published on 06 October 2019

Identification of mineralocorticoid receptor target genes in the mouse hippocampus

artículo científico publicado en 2019

Integrative epigenetic taxonomy of primary prostate cancer

artículo científico publicado en 2018

Interaction of 14-3-3 proteins with the estrogen receptor alpha F domain provides a drug target interface

artículo científico publicado en 2013

Loss of androgen receptor signaling in prostate cancer-associated fibroblasts (CAFs) promotes CCL2- and CXCL8-mediated cancer cell migration.

artículo científico publicado en 2018

Loss of p53 triggers WNT-dependent systemic inflammation to drive breast cancer metastasis

scientific article published on 31 July 2019

Loss of steroid hormone receptors is common in malignant pleural and peritoneal effusions of breast cancer patients treated with endocrine therapy.

artículo científico publicado en 2017

MYC promotes immune-suppression in triple-negative breast cancer via inhibition of interferon signaling

scientific article published in 2022

Mastermind-Like 3 Controls Proliferation and Differentiation in Neuroblastoma

artículo científico publicado en 2016

Molecular underpinnings of enzalutamide resistance

scientific article published on 01 November 2018

Neoadjuvant tamoxifen synchronizes ERα binding and gene expression profiles related to outcome and proliferation.

scientific article published on 25 April 2016

Nuclear Receptor Nur77 Limits the Macrophage Inflammatory Response through Transcriptional Reprogramming of Mitochondrial Metabolism

artículo científico publicado en 2018

Oestrogen receptor-co-factor-chromatin specificity in the transcriptional regulation of breast cancer.

artículo científico publicado en 2011

Oestrogen receptor–co-factor–chromatin specificity in the transcriptional regulation of breast cancer.

artículo científico publicado en 2011

Opposing transcriptional programs of KLF5 and AR emerge during therapy for advanced prostate cancer

artículo científico publicado en 2021

Optimized ChIP-seq method facilitates transcription factor profiling in human tumors

scientific article published on 28 December 2018

PKA phosphorylation redirects ERα to promoters of a unique gene set to induce tamoxifen resistance

artículo científico publicado en 2012

PKA-induced phosphorylation of ERα at serine 305 and high PAK1 levels is associated with sensitivity to tamoxifen in ER-positive breast cancer

artículo científico publicado en 2010

PKA-induced resistance to tamoxifen is associated with an altered orientation of ERalpha towards co-activator SRC-1

artículo científico publicado en 2007

Perturbation of Estrogen Receptor α Localization with Synthetic Nona-Arginine LXXLL-Peptide Coactivator Binding Inhibitors

artículo científico publicado en 2009

Phosphorylation of activating transcription factor-2 (ATF-2) within the activation domain is a key determinant of sensitivity to tamoxifen in breast cancer

artículo científico publicado en 2014

Presenting antigen presentation in living cells using biophysical techniques

artículo científico publicado en 2005

Prostate cancer reactivates developmental epigenomic programs during metastatic progression

artículo científico publicado en 2020

Protein Kinase A-induced tamoxifen resistance is mediated by anchoring protein AKAP13.

artículo científico publicado en 2015

Resistance to antiestrogen arzoxifene is mediated by overexpression of cyclin D1.

artículo científico publicado en 2009

SRC3 Phosphorylation at Serine 543 Is a Positive Independent Prognostic Factor in ER-Positive Breast Cancer

artículo científico publicado en 2015

Spatial separation of HLA-DM/HLA-DR interactions within MIIC and phagosome-induced immune escape.

artículo científico publicado en 2005

TLE3 loss confers AR inhibitor resistance by facilitating GR-mediated human prostate cancer cell growth

artículo científico publicado en 2019

Tamoxifen resistance: from bench to bedside.

artículo científico

Targeting BAP1: a new paradigm for mesothelioma.

artículo científico publicado en 2017

The Effects of Enzalutamide Monotherapy on Multiparametric 3T MR Imaging in Prostate Cancer.

artículo científico publicado en 2016

The Estrogen Receptor α-Cistrome Beyond Breast Cancer.

artículo científico publicado en 2016

The circadian cryptochrome, CRY1, is a pro-tumorigenic factor that rhythmically modulates DNA repair

artículo científico publicado en 2021

The first decade of estrogen receptor cistromics in breast cancer

artículo científico publicado en 2016

The hinge region of the human estrogen receptor determines functional synergy between AF-1 and AF-2 in the quantitative response to estradiol and tamoxifen.

artículo científico publicado en 2010

The invariant chain transports TNF family member CD70 to MHC class II compartments in dendritic cells.

artículo científico publicado en 2010

The transcriptional co-factor RIP140 regulates mammary gland development by promoting the generation of key mitogenic signals

artículo científico publicado en 2013

Trophoblast Glycoprotein is Associated With a Favorable Outcome for Mesothelioma and a Target for Antibody Drug Conjugates

artículo científico publicado en 2018

USP9X downregulation renders breast cancer cells resistant to tamoxifen

artículo científico publicado en 2014

VAV3 mediates resistance to breast cancer endocrine therapy.

artículo científico publicado en 2014

Visualizing the action of steroid hormone receptors in living cells

artículo científico publicado en 2007

mTOR pathway activation is a favorable prognostic factor in human prostate adenocarcinoma.

artículo científico publicado en 2016

Lista de obras de

A CRISPR-Cas9 screen identifies essential CTCF anchor sites for estrogen receptor-driven breast cancer cell proliferation

A carrier-assisted ChIP-seq method for estrogen receptor-chromatin interactions from breast cancer core needle biopsy samples.

A review of estrogen receptor/androgen receptor genomics in male breast cancer

APOBEC3B-Mediated Cytidine Deamination Is Required for Estrogen Receptor Action in Breast Cancer

Activation of endosomal dynein motors by stepwise assembly of Rab7-RILP-p150Glued, ORP1L, and the receptor betalll spectrin

An Antiestrogenic Activity Score for tamoxifen and its metabolites is associated with breast cancer outcome.

An androgen receptor switch underlies lineage infidelity in treatment-resistant prostate cancer

Androgen receptor DNA binding and chromatin accessibility profiling in prostate cancer.

Androgen receptor enhancer usage and the chromatin regulatory landscape in human prostate cancers

Androgen receptor moonlighting in the prostate cancer microenvironment.

Androgen receptor profiling predicts prostate cancer outcome

Androgen receptor signalling in macrophages promotes TREM-1-mediated prostate cancer cell line migration and invasion

BRCA1-associated mammary tumorigenesis is dependent on estrogen rather than progesterone signaling

CHD1 Loss Alters AR Binding at Lineage-Specific Enhancers and Modulates Distinct Transcriptional Programs to Drive Prostate Tumorigenesis

CHD1 Loss Alters AR Binding at Lineage-Specific Enhancers and Modulates Distinct Transcriptional Programs to Drive Prostate Tumorigenesis

CUEDC1 is a primary target of ERα essential for the growth of breast cancer cells

Can predictive biomarkers in breast cancer guide adjuvant endocrine therapy?

Characterizing steroid hormone receptor chromatin binding landscapes in male and female breast cancer.

Chemical profiling of primary mesothelioma cultures defines subtypes with different expression profiles and clinical responses.

Cholesterol sensor ORP1L contacts the ER protein VAP to control Rab7-RILP-p150 Glued and late endosome positioning

Classification of anti-estrogens according to intramolecular FRET effects on phospho-mutants of estrogen receptor alpha.

Co-regulated gene expression by oestrogen receptor α and liver receptor homolog-1 is a feature of the oestrogen response in breast cancer cells.

Cognitive effects of endocrine therapy for breast cancer: keep calm and carry on?

Comparative Cistromics Reveals Genomic Cross-talk between FOXA1 and ERα in Tamoxifen-Associated Endometrial Carcinomas.

Complex formation and function of estrogen receptor α in transcription requires RIP140.

Discovery of naturally occurring ESR1 mutations in breast cancer cell lines modelling endocrine resistance

Dissecting the predictive value of MAPK/AKT/estrogen-receptor phosphorylation axis in primary breast cancer to treatment response for tamoxifen over exemestane: a Translational Report of the Intergroup Exemestane Study (IES)-PathIES

Drug-Induced Epigenomic Plasticity Reprograms Circadian Rhythm Regulation to Drive Prostate Cancer toward Androgen Independence

Drug-induced histone eviction from open chromatin contributes to the chemotherapeutic effects of doxorubicin

Dual functions of SPOP and ERG dictate androgen therapy responses in prostate cancer

ERα activity depends on interaction and target site corecruitment with phosphorylated CREB1

Effects of Pharmacogenetics on the Pharmacokinetics and Pharmacodynamics of Tamoxifen

Endogenous androgen receptor proteomic profiling reveals genomic subcomplex involved in prostate tumorigenesis

Enzalutamide therapy for advanced prostate cancer: efficacy, resistance and beyond

Estrogen receptor α wields treatment-specific enhancers between morphologically similar endometrial tumors.

Estrogen receptor-positive breast cancer: a multidisciplinary challenge.

Extensive androgen receptor enhancer heterogeneity in primary prostate cancers underlies transcriptional diversity and metastatic potential

FOXA1 levels are decreased in pleural breast cancer metastases after adjuvant endocrine therapy, and this is associated with poor outcome

Frequent clonal relations between metastases and non-index prostate cancer lesions

Functional genetic screens for enhancer elements in the human genome using CRISPR-Cas9.

GATA3 Truncating Mutations Promote Cistromic Re-Programming In Vitro, but Not Mammary Tumor Formation in Mice

Genome-wide epigenetic profiling of breast cancer tumors treated with aromatase inhibitors.

Glucocorticoid receptor triggers a reversible drug-tolerant dormancy state with acquired therapeutic vulnerabilities in lung cancer

Hallmarks of aromatase inhibitor drug resistance revealed by epigenetic profiling in breast cancer.

IGF-1R pathway activation as putative biomarker for linsitinib therapy to revert tamoxifen resistance in ER-positive breast cancer

Identification of mineralocorticoid receptor target genes in the mouse hippocampus

Integrative epigenetic taxonomy of primary prostate cancer

Interaction of 14-3-3 proteins with the estrogen receptor alpha F domain provides a drug target interface

Loss of androgen receptor signaling in prostate cancer-associated fibroblasts (CAFs) promotes CCL2- and CXCL8-mediated cancer cell migration.

Loss of p53 triggers WNT-dependent systemic inflammation to drive breast cancer metastasis

Loss of steroid hormone receptors is common in malignant pleural and peritoneal effusions of breast cancer patients treated with endocrine therapy.

MYC promotes immune-suppression in triple-negative breast cancer via inhibition of interferon signaling

Mastermind-Like 3 Controls Proliferation and Differentiation in Neuroblastoma

Molecular underpinnings of enzalutamide resistance

Neoadjuvant tamoxifen synchronizes ERα binding and gene expression profiles related to outcome and proliferation.

Nuclear Receptor Nur77 Limits the Macrophage Inflammatory Response through Transcriptional Reprogramming of Mitochondrial Metabolism

Oestrogen receptor-co-factor-chromatin specificity in the transcriptional regulation of breast cancer.

Oestrogen receptor–co-factor–chromatin specificity in the transcriptional regulation of breast cancer.

Opposing transcriptional programs of KLF5 and AR emerge during therapy for advanced prostate cancer

Optimized ChIP-seq method facilitates transcription factor profiling in human tumors

PKA phosphorylation redirects ERα to promoters of a unique gene set to induce tamoxifen resistance

PKA-induced phosphorylation of ERα at serine 305 and high PAK1 levels is associated with sensitivity to tamoxifen in ER-positive breast cancer

PKA-induced resistance to tamoxifen is associated with an altered orientation of ERalpha towards co-activator SRC-1

Perturbation of Estrogen Receptor α Localization with Synthetic Nona-Arginine LXXLL-Peptide Coactivator Binding Inhibitors

Phosphorylation of activating transcription factor-2 (ATF-2) within the activation domain is a key determinant of sensitivity to tamoxifen in breast cancer

Presenting antigen presentation in living cells using biophysical techniques

Prostate cancer reactivates developmental epigenomic programs during metastatic progression

Protein Kinase A-induced tamoxifen resistance is mediated by anchoring protein AKAP13.

Resistance to antiestrogen arzoxifene is mediated by overexpression of cyclin D1.

SRC3 Phosphorylation at Serine 543 Is a Positive Independent Prognostic Factor in ER-Positive Breast Cancer

Spatial separation of HLA-DM/HLA-DR interactions within MIIC and phagosome-induced immune escape.

TLE3 loss confers AR inhibitor resistance by facilitating GR-mediated human prostate cancer cell growth

Tamoxifen resistance: from bench to bedside.

Targeting BAP1: a new paradigm for mesothelioma.

The Effects of Enzalutamide Monotherapy on Multiparametric 3T MR Imaging in Prostate Cancer.

The Estrogen Receptor α-Cistrome Beyond Breast Cancer.

The circadian cryptochrome, CRY1, is a pro-tumorigenic factor that rhythmically modulates DNA repair

The first decade of estrogen receptor cistromics in breast cancer

The hinge region of the human estrogen receptor determines functional synergy between AF-1 and AF-2 in the quantitative response to estradiol and tamoxifen.