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A new ER-specific photosensitizer unravels (1)O2-driven protein oxidation and inhibition of deubiquitinases as a generic mechanism for cancer PDT.

artículo científico publicado en 2015

An Integrated Global Analysis of Compartmentalized HRAS Signaling

artículo científico publicado en 2019

Author Correction: Chemosensitivity profiling of osteosarcoma tumour cell lines identifies a model of BRCAness

artículo científico publicado en 2018

Carbon dioxide-dependent regulation of NF-κB family members RelB and p100 gives molecular insight into CO2-dependent immune regulation.

artículo científico publicado en 2017

Chemosensitivity profiling of osteosarcoma tumour cell lines identifies a model of BRCAness

artículo científico publicado en 2018

ERK1/2 MAP kinases promote cell cycle entry by rapid, kinase-independent disruption of retinoblastoma-lamin A complexes.

artículo científico publicado en 2010

ERK1/2 MAP kinases promote cell cycle entry by rapid, kinase-independent disruption of retinoblastoma–lamin A complexes.

artículo científico publicado en 2011

EglN3 hydroxylase stabilizes BIM-EL linking VHL type 2C mutations to pheochromocytoma pathogenesis and chemotherapy resistance

scientific article published on 02 August 2019

Extracellular signal-regulated kinase regulates RhoA activation and tumor cell plasticity by inhibiting guanine exchange factor H1 activity

artículo científico publicado en 2013

FIH Regulates Cellular Metabolism through Hydroxylation of the Deubiquitinase OTUB1

scientific journal article

Growth Cone Localization of the mRNA Encoding the Chromatin Regulator HMGN5 Modulates Neurite Outgrowth.

artículo científico publicado en 2015

Hypoxia Reduces the Pathogenicity of Pseudomonas aeruginosa by Decreasing the Expression of Multiple Virulence Factors.

artículo científico publicado en 2017

Mass Spectrometry and Bioinformatic Analysis of Hydroxylation-Dependent Protein-Protein Interactions

artículo científico publicado en 2018

Mxi2 promotes stimulus-independent ERK nuclear translocation

artículo científico publicado en 2007

Mxi2 sustains ERK1/2 phosphorylation in the nucleus by preventing ERK1/2 binding to phosphatases.

artículo científico publicado en 2012

NADPH oxidase-derived H2O2 subverts pathogen signaling by oxidative phosphotyrosine conversion to PB-DOPA.

artículo científico publicado en 2016

PHD3 Regulates p53 Protein Stability by Hydroxylating Proline 359

scientific article published on 01 July 2018

Prolyl hydroxylase-1 regulates hepatocyte apoptosis in an NF-κB-dependent manner.

artículo científico publicado en 2016

Regulation of IL-1β-induced NF-κB by hydroxylases links key hypoxic and inflammatory signaling pathways.

artículo científico publicado en 2013

Targeting endothelin receptor signalling overcomes heterogeneity driven therapy failure

artículo científico publicado en 2017