Lista de obras -

1,2,3,4,6-Penta-O-galloly-beta-D-glucose suppresses hypoxia-induced accumulation of hypoxia-inducible factor-1α and signaling in LNCaP prostate cancer cells.

artículo científico publicado en 2010

A new chalcone derivative (E)-3-(4-methoxyphenyl)-2-methyl-1-(3,4,5-trimethoxyphenyl)prop-2-en-1-one suppresses prostate cancer involving p53-mediated cell cycle arrests and apoptosis

artículo científico publicado el 1 de septiembre de 2012

A novel sulindac derivative lacking cyclooxygenase-inhibitory activities suppresses carcinogenesis in the transgenic adenocarcinoma of mouse prostate model.

artículo científico publicado en 2010

A synthetic decursin analog with increased in vivo stability suppresses androgen receptor signaling in vitro and in vivo.

artículo científico publicado en 2011

An oriental herbal cocktail, ka-mi-kae-kyuk-tang, exerts anti-cancer activities by targeting angiogenesis, apoptosis and metastasis.

artículo científico publicado en 2006

Anti-cancer and other bioactivities of Korean Angelica gigas Nakai (AGN) and its major pyranocoumarin compounds.

artículo científico publicado en 2012

Anti-cancer, anti-diabetic and other pharmacologic and biological activities of penta-galloyl-glucose.

artículo científico publicado en 2009

Cancer Chemoprevention with Korean Angelica: Active Compounds, Pharmacokinetics, and Human Translational Considerations.

artículo científico publicado en 2015

Cancer chemoprevention research with selenium in the post-SELECT era: Promises and challenges

artículo científico publicado en 2015

Cellular and metabolic effects of triphenylselenonium chloride in a mammary cell culture model ⬇️

artículo científico publicado el 1 de marzo de 1995

Chemopreventive Effects of Korean Angelica versus Its Major Pyranocoumarins on Two Lineages of Transgenic Adenocarcinoma of Mouse Prostate Carcinogenesis

artículo científico publicado en 2015

Chemopreventive effect of Korean Angelica root extract on TRAMP carcinogenesis and integrative "omic" profiling of affected neuroendocrine carcinomas

artículo científico publicado en 2014

Co-targeting hexokinase 2-mediated Warburg effect and ULK1-dependent autophagy suppresses tumor growth of PTEN- and TP53-deficiency-driven castration-resistant prostate cancer

artículo científico publicado en 2016

Cytochrome P450 Isoforms in the Metabolism of Decursin and Decursinol Angelate from Korean Angelica.

artículo científico publicado en 2015

Decursin and decursinol angelate inhibit estrogen-stimulated and estrogen-independent growth and survival of breast cancer cells.

artículo científico publicado en 2007

Differential involvement of reactive oxygen species in apoptosis induced by two classes of selenium compounds in human prostate cancer cells.

artículo científico publicado en 2007

Dihydromethysticin from kava blocks tobacco carcinogen 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone-induced lung tumorigenesis and differentially reduces DNA damage in A/J mice

artículo científico publicado en 2014

Dissociation of the genotoxic and growth inhibitory effects of selenium ⬇️

artículo científico publicado el 17 de julio de 1995

Galbanic Acid Isolated from Ferula assafoetida Exerts In Vivo Anti-tumor Activity in Association with Anti-angiogenesis and Anti-proliferation ⬇️

artículo científico publicado el 10 de noviembre de 2010

Galbanic acid decreases androgen receptor abundance and signaling and induces G1 arrest in prostate cancer cells ⬇️

artículo científico publicado el 9 de mayo de 2011

Gene expression changes associated with chemically induced rat mammary carcinogenesis ⬇️

artículo científico publicado el 1 de octubre de 1997

Gene expression signatures associated with suppression of TRAMP prostate carcinogenesis by a kavalactone-rich Kava fraction

artículo científico publicado en 2016

Hexokinase 2-mediated Warburg effect is required for PTEN- and p53-deficiency-driven prostate cancer growth

artículo científico publicado en 2014

In vitro metabolism of pyranocoumarin isomers decursin and decursinol angelate by liver microsomes from man and rodents.

artículo científico publicado en 2013

Involvement of autophagy induction in penta-1,2,3,4,6-O-galloyl-β-D-glucose-induced senescence-like growth arrest in human cancer cells

artículo científico publicado en 2013

Involvement of c-Jun N-terminal kinase in G2/M arrest and caspase-mediated apoptosis induced by sulforaphane in DU145 prostate cancer cells.

artículo científico publicado en 2005

Ka-mi-kae-kyuk-tang oriental herbal cocktail attenuates cyclophosphamide-induced leukopenia side effects in mouse ⬇️

artículo científico publicado el 11 de marzo de 2011

Kava blocks 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone-induced lung tumorigenesis in association with reducing O6-methylguanine DNA adduct in A/J mice

artículo científico publicado en 2014

Lobe-specific proteome changes in the dorsal-lateral and ventral prostate of TRAMP mice versus wild-type mice

artículo científico publicado en 2011

Lobe‐specific lineages of carcinogenesis in the transgenic adenocarcinoma of mouse prostate and their responses to chemopreventive selenium ⬇️

artículo científico publicado el 25 de febrero de 2011

Lung tumorigenesis suppressing effects of a commercial kava extract and its selected compounds in A/J mice

artículo científico publicado en 2011

Methyl selenium-induced vascular endothelial apoptosis is executed by caspases and principally mediated by p38 MAPK pathway

artículo científico publicado en 2004

Methylseleninic Acid Superactivates p53-Senescence Cancer Progression Barrier in Prostate Lesions of Pten-Knockout Mouse

artículo científico publicado en 2015

Methylseleninic acid inhibits microvascular endothelial G1 cell cycle progression and decreases tumor microvessel density

artículo científico publicado en 2008

Methylseleninic acid potentiates apoptosis induced by chemotherapeutic drugs in androgen-independent prostate cancer cells.

artículo científico publicado en 2005

Methylseleninic acid suppresses pancreatic cancer growth involving multiple pathways.

artículo científico publicado en 2014

Mouse prostate proteome changes induced by oral pentagalloylglucose treatment suggest targets for cancer chemoprevention.

artículo científico publicado en 2011

Mouse prostate proteomes are differentially altered by supranutritional intake of four selenium compounds

artículo científico publicado en 2011

Optimizing live-animal bioluminescence imaging prediction of tumor burden in human prostate cancer xenograft models in SCID-NSG mice

scientific article published on 08 April 2019

Penta-1,2,3,4,6-O-galloyl-beta-D-glucose induces p53 and inhibits STAT3 in prostate cancer cells in vitro and suppresses prostate xenograft tumor growth in vivo.

artículo científico publicado en 2008

Penta-O-galloyl-beta-D-glucose induces G1 arrest and DNA replicative S-phase arrest independently of cyclin-dependent kinase inhibitor 1A, cyclin-dependent kinase inhibitor 1B and P53 in human breast cancer cells and is orally active against triple n

artículo científico publicado en 2010

Pentagalloylglucose induces autophagy and caspase-independent programmed deaths in human PC-3 and mouse TRAMP-C2 prostate cancer cells.

artículo científico publicado en 2009

Penta‐1,2,3,4,6‐O‐galloyl‐beta‐D‐glucose induces senescence‐like terminal S‐phase arrest in human hepatoma and breast cancer cells ⬇️

artículo científico publicado el 11 de febrero de 2011

Persistent p21Cip1 induction mediates G(1) cell cycle arrest by methylseleninic acid in DU145 prostate cancer cells.

artículo científico publicado en 2010

Phenylbutyl isoselenocyanate induces reactive oxygen species to inhibit androgen receptor and to initiate p53-mediated apoptosis in LNCaP prostate cancer cells

artículo científico publicado en 2018

Potent antiandrogen and androgen receptor activities of an Angelica gigas-containing herbal formulation: identification of decursin as a novel and active compound with implications for prevention and treatment of prostate cancer.

artículo científico publicado en 2006

Preparation of penta-O-galloyl-β-d-glucose from tannic acid and plasma pharmacokinetic analyses by liquid–liquid extraction and reverse-phase HPLC ⬇️

artículo científico publicado el 29 de septiembre de 2010

Proteomic and transcriptomic profiling of Pten gene-knockout mouse model of prostate cancer

scientific article published on 12 March 2020

Proteomic profiling of potential molecular targets of methyl-selenium compounds in the transgenic adenocarcinoma of mouse prostate model.

artículo científico publicado en 2010

Pyranocoumarin Tissue Distribution, Plasma Metabolome and Prostate Transcriptome Impacts of Sub-Chronic Exposure to Korean Angelica Supplement in Mice

artículo científico publicado en 2016

Quantitative Determination of Decursin, Decursinol Angelate, and Decursinol in Mouse Plasma and Tumor Tissue Using Liquid-Liquid Extraction and HPLC ⬇️

artículo científico publicado el 24 de noviembre de 2011

Rasmay mediate mammary cancer promotion by high fat ⬇️

artículo científico publicado el 1 de enero de 1995

Role of P53-Senescence Induction in Suppression of LNCaP Prostate Cancer Growth by Cardiotonic Compound Bufalin

scientific article published on 30 August 2018

Selenite-induced p53 Ser-15 phosphorylation and caspase-mediated apoptosis in LNCaP human prostate cancer cells.

artículo científico publicado en 2004

Single Oral Dose Pharmacokinetics of Decursin, Decursinol Angelate, and Decursinol in Rats ⬇️

artículo científico publicado el 30 de enero de 2013

Single oral dose pharmacokinetics of decursin and decursinol angelate in healthy adult men and women.

artículo científico publicado en 2015

Superior in vivo inhibitory efficacy of methylseleninic acid against human prostate cancer over selenomethionine or selenite.

artículo científico publicado en 2008

Tanshinone IIA induces mitochondria dependent apoptosis in prostate cancer cells in association with an inhibition of phosphoinositide 3-kinase/AKT pathway.

artículo científico publicado en 2010

Tanshinones from Chinese Medicinal Herb Danshen (Salvia miltiorrhiza Bunge) Suppress Prostate Cancer Growth and Androgen Receptor Signaling ⬇️

artículo científico publicado el 27 de enero de 2012

Tanshinones: Sources, Pharmacokinetics and Anti-Cancer Activities ⬇️

artículo científico publicado el 22 de octubre de 2012

Lista de obras de

1,2,3,4,6-Penta-O-galloly-beta-D-glucose suppresses hypoxia-induced accumulation of hypoxia-inducible factor-1α and signaling in LNCaP prostate cancer cells.

A new chalcone derivative (E)-3-(4-methoxyphenyl)-2-methyl-1-(3,4,5-trimethoxyphenyl)prop-2-en-1-one suppresses prostate cancer involving p53-mediated cell cycle arrests and apoptosis

A novel sulindac derivative lacking cyclooxygenase-inhibitory activities suppresses carcinogenesis in the transgenic adenocarcinoma of mouse prostate model.

A synthetic decursin analog with increased in vivo stability suppresses androgen receptor signaling in vitro and in vivo.

An oriental herbal cocktail, ka-mi-kae-kyuk-tang, exerts anti-cancer activities by targeting angiogenesis, apoptosis and metastasis.

Anti-cancer and other bioactivities of Korean Angelica gigas Nakai (AGN) and its major pyranocoumarin compounds.

Anti-cancer, anti-diabetic and other pharmacologic and biological activities of penta-galloyl-glucose.

Cancer Chemoprevention with Korean Angelica: Active Compounds, Pharmacokinetics, and Human Translational Considerations.

Cancer chemoprevention research with selenium in the post-SELECT era: Promises and challenges

Cellular and metabolic effects of triphenylselenonium chloride in a mammary cell culture model ⬇️

Chemopreventive Effects of Korean Angelica versus Its Major Pyranocoumarins on Two Lineages of Transgenic Adenocarcinoma of Mouse Prostate Carcinogenesis

Chemopreventive effect of Korean Angelica root extract on TRAMP carcinogenesis and integrative "omic" profiling of affected neuroendocrine carcinomas

Co-targeting hexokinase 2-mediated Warburg effect and ULK1-dependent autophagy suppresses tumor growth of PTEN- and TP53-deficiency-driven castration-resistant prostate cancer

Cytochrome P450 Isoforms in the Metabolism of Decursin and Decursinol Angelate from Korean Angelica.

Decursin and decursinol angelate inhibit estrogen-stimulated and estrogen-independent growth and survival of breast cancer cells.

Differential involvement of reactive oxygen species in apoptosis induced by two classes of selenium compounds in human prostate cancer cells.

Dihydromethysticin from kava blocks tobacco carcinogen 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone-induced lung tumorigenesis and differentially reduces DNA damage in A/J mice

Dissociation of the genotoxic and growth inhibitory effects of selenium ⬇️

Galbanic Acid Isolated from Ferula assafoetida Exerts In Vivo Anti-tumor Activity in Association with Anti-angiogenesis and Anti-proliferation ⬇️

Galbanic acid decreases androgen receptor abundance and signaling and induces G1 arrest in prostate cancer cells ⬇️

Gene expression changes associated with chemically induced rat mammary carcinogenesis ⬇️

Gene expression signatures associated with suppression of TRAMP prostate carcinogenesis by a kavalactone-rich Kava fraction

Hexokinase 2-mediated Warburg effect is required for PTEN- and p53-deficiency-driven prostate cancer growth

In vitro metabolism of pyranocoumarin isomers decursin and decursinol angelate by liver microsomes from man and rodents.

Involvement of autophagy induction in penta-1,2,3,4,6-O-galloyl-β-D-glucose-induced senescence-like growth arrest in human cancer cells

Involvement of c-Jun N-terminal kinase in G2/M arrest and caspase-mediated apoptosis induced by sulforaphane in DU145 prostate cancer cells.

Ka-mi-kae-kyuk-tang oriental herbal cocktail attenuates cyclophosphamide-induced leukopenia side effects in mouse ⬇️

Kava blocks 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone-induced lung tumorigenesis in association with reducing O6-methylguanine DNA adduct in A/J mice

Lobe-specific proteome changes in the dorsal-lateral and ventral prostate of TRAMP mice versus wild-type mice

Lobe‐specific lineages of carcinogenesis in the transgenic adenocarcinoma of mouse prostate and their responses to chemopreventive selenium ⬇️

Lung tumorigenesis suppressing effects of a commercial kava extract and its selected compounds in A/J mice

Methyl selenium-induced vascular endothelial apoptosis is executed by caspases and principally mediated by p38 MAPK pathway

Methylseleninic Acid Superactivates p53-Senescence Cancer Progression Barrier in Prostate Lesions of Pten-Knockout Mouse

Methylseleninic acid inhibits microvascular endothelial G1 cell cycle progression and decreases tumor microvessel density

Methylseleninic acid potentiates apoptosis induced by chemotherapeutic drugs in androgen-independent prostate cancer cells.

Methylseleninic acid suppresses pancreatic cancer growth involving multiple pathways.

Mouse prostate proteome changes induced by oral pentagalloylglucose treatment suggest targets for cancer chemoprevention.

Mouse prostate proteomes are differentially altered by supranutritional intake of four selenium compounds

Optimizing live-animal bioluminescence imaging prediction of tumor burden in human prostate cancer xenograft models in SCID-NSG mice

Penta-1,2,3,4,6-O-galloyl-beta-D-glucose induces p53 and inhibits STAT3 in prostate cancer cells in vitro and suppresses prostate xenograft tumor growth in vivo.

Penta-O-galloyl-beta-D-glucose induces G1 arrest and DNA replicative S-phase arrest independently of cyclin-dependent kinase inhibitor 1A, cyclin-dependent kinase inhibitor 1B and P53 in human breast cancer cells and is orally active against triple n

Pentagalloylglucose induces autophagy and caspase-independent programmed deaths in human PC-3 and mouse TRAMP-C2 prostate cancer cells.

Penta‐1,2,3,4,6‐O‐galloyl‐beta‐D‐glucose induces senescence‐like terminal S‐phase arrest in human hepatoma and breast cancer cells ⬇️

Persistent p21Cip1 induction mediates G(1) cell cycle arrest by methylseleninic acid in DU145 prostate cancer cells.

Phenylbutyl isoselenocyanate induces reactive oxygen species to inhibit androgen receptor and to initiate p53-mediated apoptosis in LNCaP prostate cancer cells

Potent antiandrogen and androgen receptor activities of an Angelica gigas-containing herbal formulation: identification of decursin as a novel and active compound with implications for prevention and treatment of prostate cancer.

Preparation of penta-O-galloyl-β-d-glucose from tannic acid and plasma pharmacokinetic analyses by liquid–liquid extraction and reverse-phase HPLC ⬇️

Proteomic and transcriptomic profiling of Pten gene-knockout mouse model of prostate cancer

Proteomic profiling of potential molecular targets of methyl-selenium compounds in the transgenic adenocarcinoma of mouse prostate model.

Pyranocoumarin Tissue Distribution, Plasma Metabolome and Prostate Transcriptome Impacts of Sub-Chronic Exposure to Korean Angelica Supplement in Mice

Quantitative Determination of Decursin, Decursinol Angelate, and Decursinol in Mouse Plasma and Tumor Tissue Using Liquid-Liquid Extraction and HPLC ⬇️

Rasmay mediate mammary cancer promotion by high fat ⬇️

Role of P53-Senescence Induction in Suppression of LNCaP Prostate Cancer Growth by Cardiotonic Compound Bufalin

Selenite-induced p53 Ser-15 phosphorylation and caspase-mediated apoptosis in LNCaP human prostate cancer cells.

Single Oral Dose Pharmacokinetics of Decursin, Decursinol Angelate, and Decursinol in Rats ⬇️

Single oral dose pharmacokinetics of decursin and decursinol angelate in healthy adult men and women.

Superior in vivo inhibitory efficacy of methylseleninic acid against human prostate cancer over selenomethionine or selenite.

Tanshinone IIA induces mitochondria dependent apoptosis in prostate cancer cells in association with an inhibition of phosphoinositide 3-kinase/AKT pathway.

Tanshinones from Chinese Medicinal Herb Danshen (Salvia miltiorrhiza Bunge) Suppress Prostate Cancer Growth and Androgen Receptor Signaling ⬇️

Tanshinones: Sources, Pharmacokinetics and Anti-Cancer Activities ⬇️