Lista de obras -

1-Substituted-5-[(3,5-dinitrobenzyl)sulfanyl]-1H-tetrazoles and their isosteric analogs: A new class of selective antitubercular agents active against drug-susceptible and multidrug-resistant mycobacteria

artículo científico publicado en 2014

Ammonium carbamates as highly active transdermal permeation enhancers with a dual mechanism of action

artículo científico publicado en 2010

Amphiphilic transdermal permeation enhancers: structure-activity relationships.

artículo científico publicado en 2005

Aroylhydrazone iron chelators: Tuning antioxidant and antiproliferative properties by hydrazide modifications.

artículo científico publicado en 2016

Behavior of 1-Deoxy-, 3-Deoxy- and N-Methyl-Ceramides in Skin Barrier Lipid Models

artículo científico publicado en 2020

Biodegradable derivatives of tranexamic acid as transdermal permeation enhancers.

artículo científico publicado en 2005

Ceramide analogue 14S24 ((S)-2-tetracosanoylamino-3-hydroxypropionic acid tetradecyl ester) is effective in skin barrier repair in vitro.

artículo científico publicado en 2004

Ceramide analogue 14S24 selectively recovers perturbed human skin barrier.

artículo científico publicado en 2007

Ceramides in the Skin Lipid Membranes: Length Matters

scientific article published on 06 December 2013

Ceramides with a pentadecasphingosine chain and short acyls have strong permeabilization effects on skin and model lipid membranes

scientific article published on 23 November 2015

Chromatographic methods for the separation of biocompatible iron chelators from their synthetic precursors and iron chelates.

artículo científico publicado en 2004

Comparison of suction blistering and tape stripping for analysis of epidermal genes, proteins and lipids

artículo científico publicado en 2017

Complex modulation of peptidolytic activity of cathepsin D by sphingolipids

artículo científico publicado en 2011

Development of 3,5-Dinitrobenzylsulfanyl-1,3,4-oxadiazoles and Thiadiazoles as Selective Antitubercular Agents Active Against Replicating and Nonreplicating Mycobacterium tuberculosis

artículo científico publicado en 2016

Development of water-soluble 3,5-dinitrophenyl tetrazole and oxadiazole antitubercular agents.

artículo científico publicado en 2017

Different Phase Behavior and Packing of Ceramides with Long (C16) and Very Long (C24) Acyls in Model Membranes: Infrared Spectroscopy Using Deuterated Lipids

scientific article published on 21 August 2014

Dimethylamino acid esters as biodegradable and reversible transdermal permeation enhancers: effects of linking chain length, chirality and polyfluorination.

artículo científico publicado en 2008

Dodecyl Amino Glucoside Enhances Transdermal and Topical Drug Delivery via Reversible Interaction with Skin Barrier Lipids.

artículo científico publicado en 2017

Effect of ceramide acyl chain length on skin permeability and thermotropic phase behavior of model stratum corneum lipid membranes

artículo científico publicado en 2010

Effects of 6-Hydroxyceramides on the Thermotropic Phase Behavior and Permeability of Model Skin Lipid Membranes.

artículo científico publicado en 2017

Effects of Ceramide and Dihydroceramide Stereochemistry at C-3 on the Phase Behavior and Permeability of Skin Lipid Membranes

artículo científico publicado en 2017

Effects of omega-O-acylceramide structures and concentrations in healthy and diseased skin barrier lipid membrane models

artículo científico publicado en 2019

Effects of sphingomyelin/ceramide ratio on the permeability and microstructure of model stratum corneum lipid membranes

artículo científico publicado en 2014

Emerging small-molecule compounds for treatment of atopic dermatitis: a review.

artículo científico

Enhanced Topical and Transdermal Delivery of Antineoplastic and Antiviral Acyclic Nucleoside Phosphonate cPr-PMEDAP

artículo científico publicado en 2011

Esters of 6-aminohexanoic acid as skin permeation enhancers: The effect of branching in the alkanol moiety.

artículo científico publicado en 2005

Esters of terpene alcohols as highly potent, reversible, and low toxic skin penetration enhancers

artículo científico publicado en 2019

Fibroblast origin shapes tissue homeostasis, epidermal differentiation, and drug uptake

artículo científico publicado en 2019

Filaggrin deficiency leads to impaired lipid profile and altered acidification pathways in a 3D skin construct

artículo científico publicado en 2013

Fluorescent Penetration Enhancers Reveal Complex Interactions among the Enhancer, Drug, Solvent, and Skin

artículo científico publicado en 2019

Galactosyl Pentadecene Reversibly Enhances Transdermal and Topical Drug Delivery.

artículo científico publicado en 2017

HPLC method for determination of in vitro delivery through and into porcine skin of adefovir (PMEA)

artículo científico publicado en 2007

HPLC study on stability of pyridoxal isonicotinoyl hydrazone.

artículo científico publicado en 2005

Hydrophilic interaction liquid chromatography in the separation of a moderately lipophilic drug from its highly polar metabolites--the cardioprotectant dexrazoxane as a model case.

artículo científico publicado en 2010

In Vitro Characterization of the Pharmacological Properties of the Anti-Cancer Chelator, Bp4eT, and Its Phase I Metabolites

artículo científico publicado en 2015

Influence of terminal branching on the transdermal permeation-enhancing activity in fatty alcohols and acids

scientific article published on 07 September 2006

Interactions of hyaluronic Acid with the skin and implications for the dermal delivery of biomacromolecules.

artículo científico publicado en 2015

L-Serine and glycine based ceramide analogues as transdermal permeation enhancers: polar head size and hydrogen bonding

artículo científico publicado en 2003

LC-MS/MS identification of the principal in vitro and in vivo phase I metabolites of the novel thiosemicarbazone anti-cancer drug, Bp4eT.

artículo científico publicado en 2012

Long and very long lamellar phases in model stratum corneum lipid membranes

scientific article published on 18 March 2019

Mathematical calculations of iron complex stoichiometry by direct UV-Vis spectrophotometry.

artículo científico publicado en 2013

New fluorine-containing hydrazones active against MDR-tuberculosis ⬇️

artículo científico publicado el 5 de agosto de 2011

Omega-O-Acylceramides in Skin Lipid Membranes: Effects of Concentration, Sphingoid Base, and Model Complexity on Microstructure and Permeability.

artículo científico publicado en 2016

Permeability Barrier and Microstructure of Skin Lipid Membrane Models of Impaired Glucosylceramide Processing.

artículo científico publicado en 2017

Permeability and microstructure of model stratum corneum lipid membranes containing ceramides with long (C16) and very long (C24) acyl chains.

artículo científico publicado en 2017

Permeation enhancers in transdermal drug delivery: benefits and limitations

scientific article published on 14 January 2020

Phase separation in ceramide[NP] containing lipid model membranes: neutron diffraction and solid-state NMR.

artículo científico publicado en 2017

Phytosphingosine, sphingosine and dihydrosphingosine ceramides in model skin lipid membranes: permeability and biophysics.

artículo científico publicado en 2017

Probing the role of the ceramide acyl chain length and sphingosine unsaturation in model skin barrier lipid mixtures by (2)H solid-state NMR spectroscopy

artículo científico publicado en 2015

S-substituted 3,5-dinitrophenyl 1,3,4-oxadiazole-2-thiols and tetrazole-5-thiols as highly efficient antitubercular agents

scientific article published on 21 November 2016

SAMPA: A free software tool for skin and membrane permeation data analysis.

artículo científico publicado en 2017

Scalable Synthesis of Human Ultralong Chain Ceramides

artículo científico publicado en 2015

Short-chain ceramides decrease skin barrier properties.

artículo científico publicado en 2008

Structural Changes in Ceramide Bilayers Rationalize Increased Permeation through Stratum Corneum Models with Shorter Acyl Tails

artículo científico publicado en 2015

Structure-Activity Relationships of Nitro-Substituted Aroylhydrazone Iron Chelators with Antioxidant and Antiproliferative Activities

artículo científico publicado en 2018

Structure-activity relationship studies on 3,5-dinitrophenyl tetrazoles as antitubercular agents

artículo científico publicado en 2017

Structure-activity relationships of novel salicylaldehyde isonicotinoyl hydrazone (SIH) analogs: iron chelation, anti-oxidant and cytotoxic properties.

artículo científico publicado en 2014

Synthesis and enhancing effect of transkarbam 12 on the transdermal delivery of theophylline, clotrimazole, flobufen, and griseofulvin.

artículo científico publicado en 2006

Synthesis and structure-activity relationships of skin ceramides.

artículo científico publicado en 2010

Synthesis and transdermal permeation-enhancing activity of carbonate and carbamate analogs of Transkarbam 12

scientific article published on 30 August 2006

Synthesis and transdermal permeation-enhancing activity of ketone, amide, and alkane analogs of Transkarbam 12.

artículo científico publicado en 2006

Synthetic ceramide analogues as skin permeation enhancers: structure-activity relationships

artículo científico publicado en 2003

TSLP is a direct trigger for T cell migration in filaggrin-deficient skin equivalents.

artículo científico publicado en 2017

The Role of the Trans Double Bond in Skin Barrier Sphingolipids: Permeability and Infrared Spectroscopic Study of Model Ceramide and Dihydroceramide Membranes

scientific article published on 07 May 2014

The chemistry and biology of 6-hydroxyceramide, the youngest member of the human sphingolipid family

artículo científico publicado en 2014

Transdermal and dermal delivery of adefovir: effects of pH and permeation enhancers.

artículo científico publicado en 2008

Transkarbams with terminal branching as transdermal permeation enhancers.

artículo científico publicado en 2008

Ultrastructural and Molecular Analysis of Ribose-Induced Glycated Reconstructed Human Skin ⬇️

scientific article published on 08 November 2018

Lista de obras de

1-Substituted-5-[(3,5-dinitrobenzyl)sulfanyl]-1H-tetrazoles and their isosteric analogs: A new class of selective antitubercular agents active against drug-susceptible and multidrug-resistant mycobacteria

Ammonium carbamates as highly active transdermal permeation enhancers with a dual mechanism of action

Amphiphilic transdermal permeation enhancers: structure-activity relationships.

Aroylhydrazone iron chelators: Tuning antioxidant and antiproliferative properties by hydrazide modifications.

Behavior of 1-Deoxy-, 3-Deoxy- and N-Methyl-Ceramides in Skin Barrier Lipid Models

Biodegradable derivatives of tranexamic acid as transdermal permeation enhancers.

Ceramide analogue 14S24 ((S)-2-tetracosanoylamino-3-hydroxypropionic acid tetradecyl ester) is effective in skin barrier repair in vitro.

Ceramide analogue 14S24 selectively recovers perturbed human skin barrier.

Ceramides in the Skin Lipid Membranes: Length Matters

Ceramides with a pentadecasphingosine chain and short acyls have strong permeabilization effects on skin and model lipid membranes

Chromatographic methods for the separation of biocompatible iron chelators from their synthetic precursors and iron chelates.

Comparison of suction blistering and tape stripping for analysis of epidermal genes, proteins and lipids

Complex modulation of peptidolytic activity of cathepsin D by sphingolipids

Development of 3,5-Dinitrobenzylsulfanyl-1,3,4-oxadiazoles and Thiadiazoles as Selective Antitubercular Agents Active Against Replicating and Nonreplicating Mycobacterium tuberculosis

Development of water-soluble 3,5-dinitrophenyl tetrazole and oxadiazole antitubercular agents.

Different Phase Behavior and Packing of Ceramides with Long (C16) and Very Long (C24) Acyls in Model Membranes: Infrared Spectroscopy Using Deuterated Lipids

Dimethylamino acid esters as biodegradable and reversible transdermal permeation enhancers: effects of linking chain length, chirality and polyfluorination.

Dodecyl Amino Glucoside Enhances Transdermal and Topical Drug Delivery via Reversible Interaction with Skin Barrier Lipids.

Effect of ceramide acyl chain length on skin permeability and thermotropic phase behavior of model stratum corneum lipid membranes

Effects of 6-Hydroxyceramides on the Thermotropic Phase Behavior and Permeability of Model Skin Lipid Membranes.

Effects of Ceramide and Dihydroceramide Stereochemistry at C-3 on the Phase Behavior and Permeability of Skin Lipid Membranes

Effects of omega-O-acylceramide structures and concentrations in healthy and diseased skin barrier lipid membrane models

Effects of sphingomyelin/ceramide ratio on the permeability and microstructure of model stratum corneum lipid membranes

Emerging small-molecule compounds for treatment of atopic dermatitis: a review.

Enhanced Topical and Transdermal Delivery of Antineoplastic and Antiviral Acyclic Nucleoside Phosphonate cPr-PMEDAP

Esters of 6-aminohexanoic acid as skin permeation enhancers: The effect of branching in the alkanol moiety.

Esters of terpene alcohols as highly potent, reversible, and low toxic skin penetration enhancers

Fibroblast origin shapes tissue homeostasis, epidermal differentiation, and drug uptake

Filaggrin deficiency leads to impaired lipid profile and altered acidification pathways in a 3D skin construct

Fluorescent Penetration Enhancers Reveal Complex Interactions among the Enhancer, Drug, Solvent, and Skin

Galactosyl Pentadecene Reversibly Enhances Transdermal and Topical Drug Delivery.

HPLC method for determination of in vitro delivery through and into porcine skin of adefovir (PMEA)

HPLC study on stability of pyridoxal isonicotinoyl hydrazone.

Hydrophilic interaction liquid chromatography in the separation of a moderately lipophilic drug from its highly polar metabolites--the cardioprotectant dexrazoxane as a model case.

In Vitro Characterization of the Pharmacological Properties of the Anti-Cancer Chelator, Bp4eT, and Its Phase I Metabolites

Influence of terminal branching on the transdermal permeation-enhancing activity in fatty alcohols and acids

Interactions of hyaluronic Acid with the skin and implications for the dermal delivery of biomacromolecules.

L-Serine and glycine based ceramide analogues as transdermal permeation enhancers: polar head size and hydrogen bonding

LC-MS/MS identification of the principal in vitro and in vivo phase I metabolites of the novel thiosemicarbazone anti-cancer drug, Bp4eT.

Long and very long lamellar phases in model stratum corneum lipid membranes

Mathematical calculations of iron complex stoichiometry by direct UV-Vis spectrophotometry.

New fluorine-containing hydrazones active against MDR-tuberculosis ⬇️

Omega-O-Acylceramides in Skin Lipid Membranes: Effects of Concentration, Sphingoid Base, and Model Complexity on Microstructure and Permeability.

Permeability Barrier and Microstructure of Skin Lipid Membrane Models of Impaired Glucosylceramide Processing.

Permeability and microstructure of model stratum corneum lipid membranes containing ceramides with long (C16) and very long (C24) acyl chains.

Permeation enhancers in transdermal drug delivery: benefits and limitations

Phase separation in ceramide[NP] containing lipid model membranes: neutron diffraction and solid-state NMR.

Phytosphingosine, sphingosine and dihydrosphingosine ceramides in model skin lipid membranes: permeability and biophysics.

Probing the role of the ceramide acyl chain length and sphingosine unsaturation in model skin barrier lipid mixtures by (2)H solid-state NMR spectroscopy

S-substituted 3,5-dinitrophenyl 1,3,4-oxadiazole-2-thiols and tetrazole-5-thiols as highly efficient antitubercular agents

SAMPA: A free software tool for skin and membrane permeation data analysis.

Scalable Synthesis of Human Ultralong Chain Ceramides

Short-chain ceramides decrease skin barrier properties.

Structural Changes in Ceramide Bilayers Rationalize Increased Permeation through Stratum Corneum Models with Shorter Acyl Tails

Structure-Activity Relationships of Nitro-Substituted Aroylhydrazone Iron Chelators with Antioxidant and Antiproliferative Activities

Structure-activity relationship studies on 3,5-dinitrophenyl tetrazoles as antitubercular agents

Structure-activity relationships of novel salicylaldehyde isonicotinoyl hydrazone (SIH) analogs: iron chelation, anti-oxidant and cytotoxic properties.

Synthesis and enhancing effect of transkarbam 12 on the transdermal delivery of theophylline, clotrimazole, flobufen, and griseofulvin.

Synthesis and structure-activity relationships of skin ceramides.

Synthesis and transdermal permeation-enhancing activity of carbonate and carbamate analogs of Transkarbam 12

Synthesis and transdermal permeation-enhancing activity of ketone, amide, and alkane analogs of Transkarbam 12.

Synthetic ceramide analogues as skin permeation enhancers: structure-activity relationships

TSLP is a direct trigger for T cell migration in filaggrin-deficient skin equivalents.

The Role of the Trans Double Bond in Skin Barrier Sphingolipids: Permeability and Infrared Spectroscopic Study of Model Ceramide and Dihydroceramide Membranes

The chemistry and biology of 6-hydroxyceramide, the youngest member of the human sphingolipid family

Transdermal and dermal delivery of adefovir: effects of pH and permeation enhancers.

Transkarbams with terminal branching as transdermal permeation enhancers.

Ultrastructural and Molecular Analysis of Ribose-Induced Glycated Reconstructed Human Skin ⬇️