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Aberrant FGFR signaling mediates resistance to CDK4/6 inhibitors in ER+ breast cancer

artículo científico publicado en 2019

Activation of transcription factor c-jun in dorsal root ganglia induces VIP and NPY upregulation and contributes to the pathogenesis of neuropathic pain.

artículo científico publicado en 2006

Akt isoform-specific inhibition of MDA-MB-231 cell proliferation

artículo científico publicado el 2 de agosto de 2010

CD24 enhances DNA damage-induced apoptosis by modulating NF-κB signaling in CD44-expressing breast cancer cells

artículo científico publicado el 27 de julio de 2011

CD24 regulates cell proliferation and transforming growth factor β-induced epithelial to mesenchymal transition through modulation of integrin β1 stability.

artículo científico publicado en 2012

CD24 regulates stemness and the epithelial to mesenchymal transition through modulation of Notch1 mRNA stability by p38MAPK.

artículo científico publicado en 2014

CD44 regulates cell proliferation, migration, and invasion via modulation of c-Src transcription in human breast cancer cells

artículo científico publicado en 2015

Correction: ER+ Breast Cancers Resistant to Prolonged Neoadjuvant Letrozole Exhibit an E2F4 Transcriptional Program Sensitive to CDK4/6 Inhibitors

artículo científico publicado en 2019

Correction: PIK3CA C2 Domain Deletions Hyperactivate Phosphoinositide 3-kinase (PI3K), Generate Oncogene Dependence, and Are Exquisitely Sensitive to PI3Kα Inhibitors

artículo científico publicado en 2019

EGFR negates the proliferative effect of oncogenic HER2 in MDA-MB-231 cells

artículo científico publicado en 2015

ER+ Breast Cancers Resistant to Prolonged Neoadjuvant Letrozole Exhibit an E2F4 Transcriptional Program Sensitive to CDK4/6 Inhibitors

scientific article published on 26 March 2018

HER2 stabilizes survivin while concomitantly down-regulating survivin gene transcription by suppressing Notch cleavage.

artículo científico publicado en 2013

Induction of apoptotic cell death by Pharbitis nil extract in HER2-overexpressing MCF-7 cells

artículo científico publicado el 29 de septiembre de 2010

Kinome-Wide RNA Interference Screen Reveals a Role for PDK1 in Acquired Resistance to CDK4/6 Inhibition in ER-Positive Breast Cancer.

artículo científico publicado en 2017

PIK3CA C2 Domain Deletions Hyperactivate Phosphoinositide 3-kinase (PI3K), Generate Oncogene Dependence, and Are Exquisitely Sensitive to PI3Kα Inhibitors

artículo científico publicado en 2017

PRMT5 is an actionable therapeutic target in CDK4/6 inhibitor-resistant ER+/RB-deficient breast cancer

artículo científico publicado en 2024

Proline rich 11 (PRR11) overexpression amplifies PI3K signaling and promotes antiestrogen resistance in breast cancer

scientific article published on 30 October 2020

Protein kinase B/Akt1 inhibits autophagy by down-regulating UVRAG expression.

artículo científico publicado en 2012

S100A4 negatively regulates β-catenin by inducing the Egr-1-PTEN-Akt-GSK3β degradation pathway.

artículo científico publicado en 2014