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Acid ceramidase inhibition sensitizes human colon cancer cells to oxaliplatin through downregulation of transglutaminase 2 and β1 integrin/FAK-mediated signalling

artículo científico publicado en 2018

An integrated proteomics approach for studying the molecular pathogenesis of Dupuytren's disease

scientific article published on 01 March 2009

Basement membrane protein ladinin-1 and the MIF-CD44-β1 integrin signaling axis are implicated in laryngeal cancer metastasis.

artículo científico publicado en 2016

Bioactive Sphingolipids as Biomarkers Predictive of Disease Severity and Treatment Response in Cancer: Current Status and Translational Challenges

artículo científico publicado en 2019

Casting light on molecular events underlying anti-cancer drug treatment: what can be seen from the proteomics point of view?

artículo científico publicado en 2006

Differences between reversible (self-association) and irreversible aggregation of rHuG-CSF in carbohydrate and polyol formulations.

artículo científico publicado en 2010

Differential antiproliferative mechanisms of novel derivative of benzimidazo[1,2-alpha]quinoline in colon cancer cells depending on their p53 status.

artículo científico publicado en 2008

Dual sphingosine kinase inhibitor SKI-II enhances sensitivity to 5-fluorouracil in hepatocellular carcinoma cells via suppression of osteopontin and FAK/IGF-1R signalling.

artículo científico publicado en 2017

Eco-friendly synthesis, in vitro anti-proliferative evaluation, and 3D-QSAR analysis of a novel series of monocationic 2-aryl/heteroaryl-substituted 6-(2-imidazolinyl)benzothiazole mesylates.

artículo científico publicado en 2018

Expression of growth hormone receptor, plakoglobin and NEDD9 protein in association with tumour progression and metastasis in human breast cancer

artículo científico publicado en 2014

Global approach to perinatal medicine: functional genomics and proteomics.

artículo científico publicado en 2005

In Vitro Photodynamic Activity of N-Methylated and N-Oxidised Tripyridyl Porphyrins with Long Alkyl Chains and Their Inhibitory Activity in Sphingolipid Metabolism.

artículo científico publicado en 2018

Label-free mass spectrometric profiling of urinary proteins and metabolites from paediatric idiopathic nephrotic syndrome.

artículo científico

Metastasis: new perspectives on an old problem

artículo científico publicado en 2011

Novel coumarin derivatives containing 1,2,4-triazole, 4,5-dicyanoimidazole and purine moieties: synthesis and evaluation of their cytostatic activity.

artículo científico publicado en 2012

Novel pyrimidine-2,4-dione-1,2,3-triazole and furo[2,3-d]pyrimidine-2-one-1,2,3-triazole hybrids as potential anti-cancer agents: Synthesis, computational and X-ray analysis and biological evaluation.

artículo científico publicado en 2016

Plasma biomarker identification in S-adenosylhomocysteine hydrolase deficiency.

artículo científico publicado en 2011

Small Molecules Targeting Biological Clock; A Novel Prospective for Anti-Cancer Drugs

artículo científico publicado en 2020

Small molecule purine and pseudopurine derivatives: synthesis, cytostatic evaluations and investigation of growth inhibitory effect in non-small cell lung cancer A549.

artículo científico publicado en 2018

Sphingosine 1-Phosphate Signaling and Metabolism in Chemoprevention and Chemoresistance in Colon Cancer

artículo científico publicado en 2020

Synthesis and Anti-Proliferative Effects of Mono- and Bis-Purinomimetics Targeting Kinases

artículo científico publicado en 2017

Synthesis, in vitro anticancer and antibacterial activities and in silico studies of new 4-substituted 1,2,3-triazole-coumarin hybrids

artículo científico publicado en 2016

Targeting Tumour Metastasis: The Emerging Role of Nanotechnology

artículo científico publicado en 2020

The new 5- or 6-azapyrimidine and cyanuric acid derivatives of l-ascorbic acid bearing the free C-5 hydroxy or C-4 amino group at the ethylenic spacer: CD-spectral absolute configuration determination and biological activity evaluations

artículo científico publicado el 6 de abril de 2011

The unsaturated acyclic nucleoside analogues bearing a sterically constrained (Z)-4'-benzamido-2'-butenyl moiety: Synthesis, X-ray crystal structure study, cytostatic and antiviral activity evaluations.

artículo científico publicado en 2010

UV-induced retinal proteome changes in the rat model of age-related macular degeneration.

artículo científico publicado en 2015

Using functional genomics to identify drug targets: a Dupuytren's disease example.

artículo científico publicado en 2012