Lista de obras -

A local glucagon-like peptide 1 (GLP-1) system in human pancreatic islets.

artículo científico publicado en 2012

A red-shifted photochromic sulfonylurea for the remote control of pancreatic beta cell function.

artículo científico publicado en 2015

A role for autophagy in β-cell life and death.

artículo científico publicado en 2009

ADCY5 couples glucose to insulin secretion in human islets

artículo científico publicado en 2014

Administering 25-hydroxyvitamin D3 in vitamin D-deficient young type 1A diabetic patients reduces reactivity against islet autoantigens

artículo científico publicado en 2014

Age- and diet-dependent requirement of DJ-1 for glucose homeostasis in mice with implications for human type 2 diabetes.

artículo científico publicado en 2012

An alternative and simple method to consistently prepare viable isolated human islets for clinical transplantation

artículo científico publicado en 2004

Apoptotic, regenerative, and immune-related signaling in human islets from type 2 diabetes individuals.

artículo científico publicado en 2009

Are we overestimating the loss of beta cells in type 2 diabetes?

artículo científico publicado en 2014

Atorvastatin but Not Pravastatin Impairs Mitochondrial Function in Human Pancreatic Islets and Rat β-Cells. Direct Effect of Oxidative Stress.

artículo científico publicado en 2017

Author Correction: Atorvastatin but Not Pravastatin Impairs Mitochondrial Function in Human Pancreatic Islets and Rat β-Cells. Direct Effect of Oxidative Stress

scientific article published on 10 December 2020

Autophagy in human type 2 diabetes pancreatic beta cells.

artículo científico publicado en 2009

Beneficial effect of the nonpeptidyl low molecular weight radical scavenger IAC on cultured human islet function.

artículo científico publicado en 2008

Beta Cell Hubs Dictate Pancreatic Islet Responses to Glucose

artículo científico publicado en 2016

Class II phosphoinositide 3-kinase regulates exocytosis of insulin granules in pancreatic beta cells

scientific journal article

Co-localization of acinar markers and insulin in pancreatic cells of subjects with type 2 diabetes

artículo científico publicado en 2017

Common variant in MTNR1B associated with increased risk of type 2 diabetes and impaired early insulin secretion

artículo científico publicado en 2008

Cytokines induce endoplasmic reticulum stress in human, rat and mouse beta cells via different mechanisms

artículo científico publicado en 2015

DPP-4 is expressed in human pancreatic beta cells and its direct inhibition improves beta cell function and survival in type 2 diabetes

artículo científico publicado en 2018

Direct effects of rosuvastatin on pancreatic human beta cells.

artículo científico publicado en 2013

Discovery of molecular pathways mediating 1,25-dihydroxyvitamin D3 protection against cytokine-induced inflammation and damage of human and male mouse islets of Langerhans

artículo científico publicado en 2014

Effects of C-peptide on isolated human pancreatic islet cells

artículo científico publicado en 2007

Effects of exendin-4 on islets from type 2 diabetes patients

artículo científico publicado en 2008

Enhanced Signaling Downstream of Ribonucleic Acid-Dependent Protein Kinase-Like Kinase Potentiates Lipotoxic Endoplasmic Reticulum Stress in Human Islets.

artículo científico publicado en 2010

Enhanced signaling downstream of ribonucleic Acid-activated protein kinase-like endoplasmic reticulum kinase potentiates lipotoxic endoplasmic reticulum stress in human islets.

artículo científico publicado en 2010

Erratum to: The p66Shc redox adaptor protein is induced by saturated fatty acids and mediates lipotoxicity-induced apoptosis in pancreatic beta cells

artículo científico publicado en 2015

FGF-2b and h-PL Transform Duct and Non-Endocrine Human Pancreatic Cells into Endocrine Insulin Secreting Cells by Modulating Differentiating Genes.

artículo científico publicado en 2017

From genotype to human β cell phenotype and beyond ⬇️

artículo científico publicado el 1 de septiembre de 2012

Genetic and functional assessment of the role of the rs13431652-A and rs573225-A alleles in the G6PC2 promoter that are strongly associated with elevated fasting glucose levels.

artículo científico publicado en 2010

Gliclazide protects human islet beta-cells from apoptosis induced by intermittent high glucose

artículo científico publicado en 2007

Glucagon-like peptide 1 protects INS-1E mitochondria against palmitate-mediated beta-cell dysfunction: a proteomic study.

artículo científico publicado en 2015

Glucocorticoids Reprogram β-Cell Signaling to Preserve Insulin Secretion

artículo científico publicado en 2017

Glucolipotoxicity initiates pancreatic β-cell death through TNFR5/CD40-mediated STAT1 and NF-κB activation.

artículo científico publicado en 2016

Histopathology and ex vivo insulin secretion of pancreatic islets in gestational diabetes: A case report

scientific article published on 01 September 2011

Improved insulin secretory function and reduced chemotactic properties after tissue culture of islets from type 1 diabetic patients.

artículo científico publicado en 2004

In vitro use of free fatty acids bound to albumin: A comparison of protocols

artículo científico publicado en 2015

Incretin-modulated beta cell energetics in intact islets of Langerhans

artículo científico publicado en 2014

Insulin secretory granules labelled with phogrin-fluorescent proteins show alterations in size, mobility and responsiveness to glucose stimulation in living β-cells

article

JunB protects β-cells from lipotoxicity via the XBP1-AKT pathway

artículo científico publicado en 2014

LRH-1 agonism favours an immune-islet dialogue which protects against diabetes mellitus.

artículo científico publicado en 2018

Lipotoxicity disrupts incretin-regulated human β cell connectivity

artículo científico publicado en 2013

Mast cells infiltrate pancreatic islets in human type 1 diabetes

artículo científico publicado en 2015

MicroRNA-124a is hyperexpressed in type 2 diabetic human pancreatic islets and negatively regulates insulin secretion

artículo científico publicado en 2014

MicroRNAs miR-23a-3p, miR-23b-3p, and miR-149-5p Regulate the Expression of Proapoptotic BH3-Only Proteins DP5 and PUMA in Human Pancreatic β-Cells.

artículo científico publicado en 2016

Mitochondrial and ER-targeted eCALWY probes reveal high levels of free Zn2+.

artículo científico publicado en 2014

MondoA is an Essential Glucose Responsive Transcription Factor in Human Pancreatic Beta Cells.

artículo científico publicado en 2017

Optical control of insulin release using a photoswitchable sulfonylurea

artículo científico publicado en 2014

Palmitate activates autophagy in INS-1E β-cells and in isolated rat and human pancreatic islets

artículo científico publicado en 2012

Palmitate-induced lipotoxicity alters acetylation of multiple proteins in clonal β cells and human pancreatic islets

artículo científico publicado en 2017

Pancreatic Beta Cell Identity in Humans and the Role of Type 2 Diabetes

artículo científico publicado en 2017

Pancreatic islets from type 2 diabetic patients have functional defects and increased apoptosis that are ameliorated by metformin.

artículo científico publicado en 2004

Pancreatic β-cell protection from inflammatory stress by the endoplasmic reticulum proteins thrombospondin 1 and mesencephalic astrocyte-derived neutrotrophic factor (MANF).

artículo científico publicado en 2017

Per-arnt-sim (PAS) domain-containing protein kinase is downregulated in human islets in type 2 diabetes and regulates glucagon secretion

scientific journal article

Phenylpropenoic Acid Glucoside from Rooibos Protects Pancreatic Beta Cells against Cell Death Induced by Acute Injury

artículo científico publicado en 2016

Pleiotropic effects of GIP on islet function involve osteopontin

artículo científico publicado en 2011

Prevention by metformin of alterations induced by chronic exposure to high glucose in human islet beta cells is associated with preserved ATP/ADP ratio

scientific article published on 03 January 2014

Protective role of the ELOVL2/docosahexaenoic acid axis in glucolipotoxicity-induced apoptosis in rodent beta cells and human islets.

artículo científico publicado en 2018

Rosiglitazone prevents the impairment of human islet function induced by fatty acids: evidence for a role of PPARgamma2 in the modulation of insulin secretion.

artículo científico publicado en 2003

SRp55 Regulates a Splicing Network that Controls Human Pancreatic Beta Cell Function and Survival

artículo científico publicado en 2017

The Myokine Irisin Is Released in Response to Saturated Fatty Acids and Promotes Pancreatic β-Cell Survival and Insulin Secretion.

artículo científico publicado en 2017

The beta-cell in human type 2 diabetes.

artículo científico publicado en 2010

The direct effects of tacrolimus and cyclosporin A on isolated human islets: A functional, survival and gene expression study.

artículo científico publicado en 2009

The effects of kisspeptin on β-cell function, serum metabolites and appetite in humans

artículo científico publicado en 2018

The endoplasmic reticulum in pancreatic beta cells of type 2 diabetes patients.

artículo científico publicado en 2007

The immunoproteasome is induced by cytokines and regulates apoptosis in human islets

artículo científico publicado en 2017

The p66(Shc) redox adaptor protein is induced by saturated fatty acids and mediates lipotoxicity-induced apoptosis in pancreatic beta cells.

artículo científico publicado en 2015

The pancreatic beta cells in human type 2 diabetes.

artículo científico publicado en 2012

The type 2 diabetes-associated HMG20A gene is mandatory for islet beta cell functional maturity

artículo científico publicado en 2018

Thrombospondin 1 protects pancreatic β-cells from lipotoxicity via the PERK-NRF2 pathway.

artículo científico publicado en 2016

Transcription factors of beta-cell differentiation and maturation in isolated human islets: Effects of high glucose, high free fatty acids and type 2 diabetes

scientific article published on 31 March 2006

Ultrastructural alterations of pancreatic beta cells in human diabetes mellitus.

artículo científico publicado en 2017

Ultrastructural morphometric analysis of insulin secretory granules in human type 2 diabetes

article

Virus-like infection induces human β cell dedifferentiation.

artículo científico publicado en 2018

β-Cell inflammation in human type 2 diabetes and the role of autophagy.

artículo científico publicado en 2013

Lista de obras de

A local glucagon-like peptide 1 (GLP-1) system in human pancreatic islets.

A red-shifted photochromic sulfonylurea for the remote control of pancreatic beta cell function.

A role for autophagy in β-cell life and death.

ADCY5 couples glucose to insulin secretion in human islets

Administering 25-hydroxyvitamin D3 in vitamin D-deficient young type 1A diabetic patients reduces reactivity against islet autoantigens

Age- and diet-dependent requirement of DJ-1 for glucose homeostasis in mice with implications for human type 2 diabetes.

An alternative and simple method to consistently prepare viable isolated human islets for clinical transplantation

Apoptotic, regenerative, and immune-related signaling in human islets from type 2 diabetes individuals.

Are we overestimating the loss of beta cells in type 2 diabetes?

Atorvastatin but Not Pravastatin Impairs Mitochondrial Function in Human Pancreatic Islets and Rat β-Cells. Direct Effect of Oxidative Stress.

Author Correction: Atorvastatin but Not Pravastatin Impairs Mitochondrial Function in Human Pancreatic Islets and Rat β-Cells. Direct Effect of Oxidative Stress

Autophagy in human type 2 diabetes pancreatic beta cells.

Beneficial effect of the nonpeptidyl low molecular weight radical scavenger IAC on cultured human islet function.

Beta Cell Hubs Dictate Pancreatic Islet Responses to Glucose

Class II phosphoinositide 3-kinase regulates exocytosis of insulin granules in pancreatic beta cells

Co-localization of acinar markers and insulin in pancreatic cells of subjects with type 2 diabetes

Common variant in MTNR1B associated with increased risk of type 2 diabetes and impaired early insulin secretion

Cytokines induce endoplasmic reticulum stress in human, rat and mouse beta cells via different mechanisms

DPP-4 is expressed in human pancreatic beta cells and its direct inhibition improves beta cell function and survival in type 2 diabetes

Direct effects of rosuvastatin on pancreatic human beta cells.

Discovery of molecular pathways mediating 1,25-dihydroxyvitamin D3 protection against cytokine-induced inflammation and damage of human and male mouse islets of Langerhans

Effects of C-peptide on isolated human pancreatic islet cells

Effects of exendin-4 on islets from type 2 diabetes patients

Enhanced Signaling Downstream of Ribonucleic Acid-Dependent Protein Kinase-Like Kinase Potentiates Lipotoxic Endoplasmic Reticulum Stress in Human Islets.

Enhanced signaling downstream of ribonucleic Acid-activated protein kinase-like endoplasmic reticulum kinase potentiates lipotoxic endoplasmic reticulum stress in human islets.

Erratum to: The p66Shc redox adaptor protein is induced by saturated fatty acids and mediates lipotoxicity-induced apoptosis in pancreatic beta cells

FGF-2b and h-PL Transform Duct and Non-Endocrine Human Pancreatic Cells into Endocrine Insulin Secreting Cells by Modulating Differentiating Genes.

From genotype to human β cell phenotype and beyond ⬇️

Genetic and functional assessment of the role of the rs13431652-A and rs573225-A alleles in the G6PC2 promoter that are strongly associated with elevated fasting glucose levels.

Gliclazide protects human islet beta-cells from apoptosis induced by intermittent high glucose

Glucagon-like peptide 1 protects INS-1E mitochondria against palmitate-mediated beta-cell dysfunction: a proteomic study.

Glucocorticoids Reprogram β-Cell Signaling to Preserve Insulin Secretion

Glucolipotoxicity initiates pancreatic β-cell death through TNFR5/CD40-mediated STAT1 and NF-κB activation.

Histopathology and ex vivo insulin secretion of pancreatic islets in gestational diabetes: A case report

Improved insulin secretory function and reduced chemotactic properties after tissue culture of islets from type 1 diabetic patients.

In vitro use of free fatty acids bound to albumin: A comparison of protocols

Incretin-modulated beta cell energetics in intact islets of Langerhans

Insulin secretory granules labelled with phogrin-fluorescent proteins show alterations in size, mobility and responsiveness to glucose stimulation in living β-cells

JunB protects β-cells from lipotoxicity via the XBP1-AKT pathway

LRH-1 agonism favours an immune-islet dialogue which protects against diabetes mellitus.

Lipotoxicity disrupts incretin-regulated human β cell connectivity

Mast cells infiltrate pancreatic islets in human type 1 diabetes

MicroRNA-124a is hyperexpressed in type 2 diabetic human pancreatic islets and negatively regulates insulin secretion

MicroRNAs miR-23a-3p, miR-23b-3p, and miR-149-5p Regulate the Expression of Proapoptotic BH3-Only Proteins DP5 and PUMA in Human Pancreatic β-Cells.

Mitochondrial and ER-targeted eCALWY probes reveal high levels of free Zn2+.

MondoA is an Essential Glucose Responsive Transcription Factor in Human Pancreatic Beta Cells.

Optical control of insulin release using a photoswitchable sulfonylurea

Palmitate activates autophagy in INS-1E β-cells and in isolated rat and human pancreatic islets

Palmitate-induced lipotoxicity alters acetylation of multiple proteins in clonal β cells and human pancreatic islets

Pancreatic Beta Cell Identity in Humans and the Role of Type 2 Diabetes

Pancreatic islets from type 2 diabetic patients have functional defects and increased apoptosis that are ameliorated by metformin.

Pancreatic β-cell protection from inflammatory stress by the endoplasmic reticulum proteins thrombospondin 1 and mesencephalic astrocyte-derived neutrotrophic factor (MANF).

Per-arnt-sim (PAS) domain-containing protein kinase is downregulated in human islets in type 2 diabetes and regulates glucagon secretion

Phenylpropenoic Acid Glucoside from Rooibos Protects Pancreatic Beta Cells against Cell Death Induced by Acute Injury

Pleiotropic effects of GIP on islet function involve osteopontin

Prevention by metformin of alterations induced by chronic exposure to high glucose in human islet beta cells is associated with preserved ATP/ADP ratio

Protective role of the ELOVL2/docosahexaenoic acid axis in glucolipotoxicity-induced apoptosis in rodent beta cells and human islets.

Rosiglitazone prevents the impairment of human islet function induced by fatty acids: evidence for a role of PPARgamma2 in the modulation of insulin secretion.

SRp55 Regulates a Splicing Network that Controls Human Pancreatic Beta Cell Function and Survival

The Myokine Irisin Is Released in Response to Saturated Fatty Acids and Promotes Pancreatic β-Cell Survival and Insulin Secretion.

The beta-cell in human type 2 diabetes.

The direct effects of tacrolimus and cyclosporin A on isolated human islets: A functional, survival and gene expression study.

The effects of kisspeptin on β-cell function, serum metabolites and appetite in humans

The endoplasmic reticulum in pancreatic beta cells of type 2 diabetes patients.

The immunoproteasome is induced by cytokines and regulates apoptosis in human islets

The p66(Shc) redox adaptor protein is induced by saturated fatty acids and mediates lipotoxicity-induced apoptosis in pancreatic beta cells.

The pancreatic beta cells in human type 2 diabetes.

The type 2 diabetes-associated HMG20A gene is mandatory for islet beta cell functional maturity

Thrombospondin 1 protects pancreatic β-cells from lipotoxicity via the PERK-NRF2 pathway.

Transcription factors of beta-cell differentiation and maturation in isolated human islets: Effects of high glucose, high free fatty acids and type 2 diabetes

Ultrastructural alterations of pancreatic beta cells in human diabetes mellitus.

Ultrastructural morphometric analysis of insulin secretory granules in human type 2 diabetes

Virus-like infection induces human β cell dedifferentiation.

β-Cell inflammation in human type 2 diabetes and the role of autophagy.