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A Case of Erythema Multiforme Major Developed after Sequential Use of Two Immune Checkpoint Inhibitors, Nivolumab and Ipilimumab, for Advanced Melanoma: Possible Implication of Synergistic and/or Complementary Immunomodulatory Effects.

artículo científico publicado en 2018

A Case of Subcutaneous Sarcoidosis Occurring along the Superficial Veins of the Forearms: A Distinctive Cutaneous Manifestation Masquerading Venous Tropic Action in the Underlying Systemic Disease?

artículo científico publicado en 2017

A case of acute cutaneous graft-versus-host disease mimicking psoriasis vulgaris.

artículo científico publicado en 2008

A clue for telangiectasis in systemic sclerosis: elevated serum soluble endoglin levels in patients with the limited cutaneous form of the disease

scientific article published on 01 January 2006

A crucial role of L-selectin in C protein-induced experimental polymyositis in mice.

artículo científico publicado en 2014

A novel inhibitor of Smad-dependent transcriptional activation suppresses tissue fibrosis in mouse models of systemic sclerosis.

artículo científico publicado en 2009

A novel splenic B1 regulatory cell subset suppresses allergic disease through phosphatidylinositol 3-kinase-Akt pathway activation.

artículo científico publicado en 2016

A rare case of chronic expanding haematoma in the occipital region mimicking a malignant soft tissue tumour

artículo científico publicado en 2018

Abnormal natural killer cell function in systemic sclerosis: altered cytokine production and defective killing activity.

artículo científico publicado en 2005

Altered expression of dermokine in skin disorders

artículo científico publicado en 2012

Anti-DNA topoisomerase II alpha autoantibodies in Japanese patients with systemic sclerosis

artículo científico publicado en 2005

Anti-NXP2 autoantibodies in adult patients with idiopathic inflammatory myopathies: possible association with malignancy.

artículo científico publicado en 2012

Anti-topoisomerase I antibody levels as serum markers of skin sclerosis in systemic sclerosis.

artículo científico publicado en 2012

Antigen specificity of antihistone antibodies in connective tissue disease patients with anti-U1RNP antibodies

scientific article published on 13 July 2007

Antimelanoma differentiation-associated protein 5 antibody level is a novel tool for monitoring disease activity in rapidly progressive interstitial lung disease with dermatomyositis.

artículo científico publicado en 2016

Antiphospholipid antibodies in patients with autoimmune blistering disease.

artículo científico publicado en 2007

Association of CD22 gene polymorphism with susceptibility to limited cutaneous systemic sclerosis

artículo científico publicado en 2007

Association of IL-10 receptor 2 (IL10RB) SNP with systemic sclerosis

artículo científico publicado en 2008

Association of STAT4 polymorphism with systemic sclerosis in a Japanese population

scientific article published on 01 August 2009

Association of UBE2L3 polymorphisms with diffuse cutaneous systemic sclerosis in a Japanese population.

artículo científico publicado en 2012

Association of the FAM167A-BLK region with systemic sclerosis

artículo científico publicado en 2010

Association study of a polymorphism of the CTGF gene and susceptibility to systemic sclerosis in the Japanese population

scientific article published on 03 December 2008

Augmented ICOS expression in patients with early diffuse cutaneous systemic sclerosis.

artículo científico publicado en 2012

Autoantibodies against matrix metalloproteinase-1 in patients with localized scleroderma

artículo científico publicado en 2008

Autoantibodies to RuvBL1 and RuvBL2: a novel systemic sclerosis-related antibody associated with diffuse cutaneous and skeletal muscle involvement.

artículo científico publicado en 2014

Autoantibodies to small ubiquitin-like modifier activating enzymes in Japanese patients with dermatomyositis: comparison with a UK Caucasian cohort

artículo científico publicado en 2012

Autoantibody against caspase-3, an executioner of apoptosis, in patients with systemic sclerosis.

artículo científico publicado en 2009

Autoantibody against one of the antioxidant repair enzymes, methionine sulfoxide reductase A, in systemic sclerosis: association with pulmonary fibrosis and vascular damage.

artículo científico publicado en 2009

Autoantibody against peroxiredoxin I, an antioxidant enzyme, in patients with systemic sclerosis: possible association with oxidative stress

artículo científico publicado en 2007

B cells promote tumor immunity against B16F10 melanoma

artículo científico publicado en 2014

B-cell linker protein expression contributes to controlling allergic and autoimmune diseases by mediating IL-10 production in regulatory B cells.

artículo científico publicado en 2013

B-lymphocyte depletion reduces skin fibrosis and autoimmunity in the tight-skin mouse model for systemic sclerosis

artículo científico publicado en 2006

BAFF antagonist attenuates the development of skin fibrosis in tight-skin mice

scientific article published on 21 June 2007

BAFF inhibition attenuates fibrosis in scleroderma by modulating the regulatory and effector B cell balance

scientific article published on 11 July 2018

Basophils and mast cells play critical roles for leukocyte recruitment in IgE-mediated cutaneous reverse passive Arthus reaction

scientific article published on 23 June 2012

Biomarkers in systemic sclerosis: Their potential to predict clinical courses

artículo científico publicado en 2016

Blockade of CD40/CD40 ligand interactions attenuates skin fibrosis and autoimmunity in the tight-skin mouse.

artículo científico publicado en 2007

Blockade of Syk ameliorates the development of murine sclerodermatous chronic graft-versus-host disease

artículo científico publicado en 2014

Blockade of TGF-β/Smad signaling by the small compound HPH-15 ameliorates experimental skin fibrosis.

artículo científico publicado en 2018

Blockade of p38 Mitogen-Activated Protein Kinase Inhibits Murine Sclerodermatous Chronic Graft-versus-Host Disease.

artículo científico publicado en 2017

Both Th1 and Th2 chemokines are elevated in sera of patients with autoimmune blistering diseases

artículo científico publicado en 2006

CCL13 is a promising diagnostic marker for systemic sclerosis.

artículo científico publicado en 2009

CD19 regulates skin and lung fibrosis via Toll-like receptor signaling in a model of bleomycin-induced scleroderma.

artículo científico publicado en 2008

CD19, a response regulator of B lymphocytes, regulates wound healing through hyaluronan-induced TLR4 signaling.

scientific article published on 02 July 2009

CD34-positive infantile myofibromatosis: Case report and review of hemangiopericytoma-like pattern tumors

artículo científico publicado en 2016

Cell adhesion molecules regulate fibrotic process via Th1/Th2/Th17 cell balance in a bleomycin-induced scleroderma model.

artículo científico publicado en 2010

Certolizumab pegol, a pegylated anti-TNF-α antagonist, caused de novo-onset palmoplantar pustulosis followed by generalized pustular psoriasis in a patient with rheumatoid arthritis

artículo científico publicado en 2016

Chemokine receptors CCR2 and CX3CR1 regulate skin fibrosis in the mouse model of cytokine-induced systemic sclerosis.

artículo científico publicado en 2012

Circulating γ/δ T cells in systemic sclerosis exhibit activated phenotype and enhance gene expression of proalpha2(I) collagen of fibroblasts

artículo científico publicado en 2012

Cladophialophora bantiana infection mimicking neuromyelitis optica

artículo científico publicado en 2018

Clinical and immunologic predictors of scleroderma renal crisis in Japanese systemic sclerosis patients with anti-RNA polymerase III autoantibodies.

artículo científico publicado en 2015

Clinical association of serum CD137 (4-1BB) levels in patients with systemic sclerosis

artículo científico publicado en 2008

Clinical association of serum interleukin-17 levels in systemic sclerosis: is systemic sclerosis a Th17 disease?

scientific article published on 07 March 2008

Clinical correlations with dermatomyositis-specific autoantibodies in adult Japanese patients with dermatomyositis: a multicenter cross-sectional study.

artículo científico publicado en 2011

Clinical significance of serum HMGB-1 and sRAGE levels in systemic sclerosis: association with disease severity

scientific article published on 30 September 2008

Clonal expansion of Epstein-Barr virus (EBV)-infected γδ T cells in patients with chronic active EBV disease and hydroa vacciniforme-like eruptions.

artículo científico publicado en 2012

Common and distinct clinical features in adult patients with anti-aminoacyl-tRNA synthetase antibodies: heterogeneity within the syndrome.

artículo científico publicado en 2013

Decreased expression levels of CD22 and L-selectin on peripheral blood B lymphocytes from patients with bullous pemphigoid

artículo científico publicado en 2006

Decreased levels of autoantibody against histone deacetylase 3 in patients with systemic sclerosis.

artículo científico publicado en 2009

Decreased levels of regulatory B cells in patients with systemic sclerosis: association with autoantibody production and disease activity.

artículo científico publicado en 2015

Dermokine inhibits ELR(+)CXC chemokine expression and delays early skin wound healing.

artículo científico publicado en 2013

Dermokine-β impairs ERK signaling through direct binding to GRP78

artículo científico publicado en 2012

Dermoscopy findings of nail fold capillaries in connective tissue diseases.

artículo científico publicado en 2011

Developing classification criteria for discoid lupus erythematosus: an update from the World Congress of Dermatology 2015 meeting

artículo científico publicado en 2016

Development of classification criteria for discoid lupus erythematosus: Results of a Delphi exercise

artículo científico publicado en 2017

Diagnostic criteria, severity classification and guideline of lichen sclerosus et atrophicus

artículo científico publicado en 2017

Diagnostic criteria, severity classification and guidelines of localized scleroderma.

artículo científico publicado en 2018

Dietary supplement product composed of natural ingredients as a suspected cause of erythema multiforme: A case report and identification for the confident false positivity of lymphocyte transformation test

artículo científico publicado en 2019

Disaccharide analysis of skin glycosaminoglycan in lichen myxedematosus.

artículo científico publicado en 2008

Donor-derived regulatory B cells are important for suppression of murine sclerodermatous chronic graft-versus-host disease.

artículo científico publicado en 2013

E- and P-selectins synergistically inhibit bleomycin-induced pulmonary fibrosis

artículo científico publicado en 2006

Effects of bisphosphonate administration on the bone mass in immune thrombocytopenic purpura patients under treatment with steroids.

artículo científico publicado en 2009

Elevated circulating TWEAK levels in systemic sclerosis: association with lower frequency of pulmonary fibrosis

artículo científico publicado en 2009

Elevated serum BAFF levels in patients with localized scleroderma in contrast to other organ-specific autoimmune diseases

scientific article published on 01 February 2007

Elevated serum BAFF levels in patients with systemic sclerosis: enhanced BAFF signaling in systemic sclerosis B lymphocytes

scientific article published on 01 January 2006

Elevated serum concentrations of triggering receptor expressed on myeloid cells-1 in diffuse cutaneous systemic sclerosis: association with severity of pulmonary fibrosis

artículo científico publicado en 2010

Elevated serum insulin-like growth factor (IGF-1) and IGF binding protein-3 levels in patients with systemic sclerosis: possible role in development of fibrosis.

artículo científico publicado en 2008

Elevated serum interleukin-27 levels in patients with systemic sclerosis: association with T cell, B cell and fibroblast activation

artículo científico publicado en 2010

Elevated serum levels of APRIL, but not BAFF, in patients with atopic dermatitis

scientific article published on 02 November 2007

Elevated serum placenta growth factor (PlGF) levels in patients with systemic sclerosis: a possible role in the development of skin but not lung fibrosis

artículo científico publicado en 2010

Endothelial selectins regulate skin wound healing in cooperation with L-selectin and ICAM-1

artículo científico publicado en 2007

Erythema induratum of Bazin which occurred after tumor necrosis factor antagonist therapy.

artículo científico publicado en 2017

Esophageal transit scintigraphy and structured questionnaire in patients with systemic sclerosis with endoscopically proven reflux esophagitis

scientific article published on 24 October 2009

FTY720 ameliorates murine sclerodermatous chronic graft-versus-host disease by promoting expansion of splenic regulatory cells and inhibiting immune cell infiltration into skin.

artículo científico publicado en 2013

Fatal case of pancreatic panniculitis caused by occult neuroendocrine tumor in the corresponding organ: A case report and review of the published work

artículo científico publicado en 2020

Genital herpes due to acyclovir-sensitive herpes simplex virus caused secondary and recurrent herpetic whitlows due to thymidine kinase-deficient/temperature-sensitive virus.

artículo científico publicado en 2007

Guideline for diagnostic criteria, severity classification and treatment of eosinophilic fasciitis.

artículo científico publicado en 2017

High incidence of pulmonary arterial hypertension in systemic sclerosis patients with anti-centriole autoantibodies.

artículo científico publicado en 2013

Host-derived MCP-1 and MIP-1α regulate protective anti-tumor immunity to localized and metastatic B16 melanoma

scientific article published on 26 October 2011

Human Leukocyte Antigen and Systemic Sclerosis in Japanese: The Sign of the Four Independent Protective Alleles, DRB1*13:02, DRB1*14:06, DQB1*03:01, and DPB1*02:01.

artículo científico publicado en 2016

IL-6 blockade attenuates the development of murine sclerodermatous chronic graft-versus-host disease

artículo científico publicado en 2012

Identification of a novel autoantibody reactive with 155 and 140 kDa nuclear proteins in patients with dermatomyositis: an association with malignancy

artículo científico publicado en 2006

Identification of myocardial damage in systemic sclerosis: a nuclear cardiology approach.

artículo científico publicado en 2010

IgG4-related skin lesions in a patient with IgG4-related chronic sclerosing dacryoadenitis and sialoadenitis.

artículo científico publicado en 2011

Impact of a new simplified disability scoring system for adult patients with localized scleroderma.

artículo científico publicado en 2018

Impaired IL-17 signaling pathway contributes to the increased collagen expression in scleroderma fibroblasts

artículo científico publicado en 2012

Increased accumulation of extracellular thrombospondin-2 due to low degradation activity stimulates type I collagen expression in scleroderma fibroblasts

scientific article published on 03 December 2011

Increased cutaneous T-cell-attracting chemokine levels in sera from patients with systemic sclerosis

artículo científico publicado en 2005

Increased serum interleukin 23 in patients with systemic sclerosis

artículo científico publicado en 2007

Increased serum pentraxin 3 in patients with systemic sclerosis.

artículo científico publicado en 2009

Inducible costimulator ligand regulates bleomycin-induced lung and skin fibrosis in a mouse model independently of the inducible costimulator/inducible costimulator ligand pathway

scientific article published on 01 June 2010

Inhibition of the Progression of Skin Inflammation, Fibrosis, and Vascular Injury by Blockade of the CX3 CL1/CX3 CR1 Pathway in Experimental Mouse Models of Systemic Sclerosis

artículo científico publicado en 2019

Intercellular adhesion molecule-1 and vascular cell adhesion molecule-1 cooperatively contribute to the cutaneous Arthus reaction

scientific article published on 13 February 2007

Intercellular adhesion molecule-1 deficiency attenuates the development of skin fibrosis in tight-skin mice

artículo científico publicado en 2007

Investigation of prognostic factors for skin sclerosis and lung function in Japanese patients with early systemic sclerosis: a multicentre prospective observational study.

artículo científico publicado en 2011

L-selectin and intercellular adhesion molecule-1 regulate the development of Concanavalin A-induced liver injury

artículo científico publicado en 2006

Long-term follow-up of finger passive range of motion in Japanese systemic sclerosis patients treated with self-administered stretching.

artículo científico publicado en 2018

Low zone tolerance requires ICAM-1 expression to limit contact hypersensitivity elicitation.

artículo científico

Multiple subcutaneous cholesterol granulomas arising in eruptive vellus hair cysts: A case report and published work review of 11 cases.

artículo científico publicado en 2016

Myocardial damages in systemic sclerosis detected by gated myocardial perfusion SPECT and sympathetic imaging.

artículo científico publicado en 2006

Myositis-specific anti-155/140 autoantibodies target transcription intermediary factor 1 family proteins

scientific article published on 01 February 2012

Oropharyngeal Dysphagia in Dermatomyositis: Associations with Clinical and Laboratory Features Including Autoantibodies.

artículo científico publicado en 2016

Outline of guidelines for the management of vasculitis and vascular disorders in Japan, 2016 revised edition

artículo científico publicado en 2017

P-selectin glycoprotein ligand-1 contributes to wound healing predominantly as a p-selectin ligand and partly as an e-selectin ligand

artículo científico publicado en 2009

Pathogenesis of systemic sclerosis: altered B cell function is the key linking systemic autoimmunity and tissue fibrosis.

artículo científico publicado en 2005

Phase-dependent roles of E-selectin during chronic contact hypersensitivity responses.

artículo científico publicado en 2007

Phenotypic analysis in a case of hydroa vacciniforme-like eruptions associated with chronic active Epstein-Barr virus disease of γδ T cells

artículo científico publicado el 1 de enero de 2012

Potential immunologic targets for treating fibrosis in systemic sclerosis: a review focused on leukocytes and cytokines.

artículo científico

Prevalence and clinical characteristics of anti-Mi-2 antibodies in Japanese patients with dermatomyositis.

artículo científico publicado en 2005

Prevalence of Pruritus in Cutaneous Lupus Erythematosus: Brief Report of a Multicenter, Multinational Cross-Sectional Study

artículo científico publicado en 2018

Preventive effects of topical washing with miconazole nitrate-containing soap to diaper candidiasis in hospitalized elderly patients: A prospective, double-blind, placebo-controlled study.

artículo científico publicado en 2017

Prospective trial for the clinical efficacy of anogenital skin care with miconazole nitrate-containing soap for diaper candidiasis

artículo científico publicado en 2020

RXRB Is an MHC-Encoded Susceptibility Gene Associated with Anti-Topoisomerase I Antibody-Positive Systemic Sclerosis.

artículo científico publicado en 2017

Re-emergence of anti-topoisomerase I antibody with exacerbated development of skin sclerosis in a patient with systemic sclerosis.

artículo científico publicado en 2009

Reactive hemophagocytic syndrome in a patient with polyarteritis nodosa associated with Epstein-Barr virus reactivation.

artículo científico publicado en 2006

Redefining cutaneous lupus erythematosus: a proposed international consensus approach and results of a preliminary questionnaire.

artículo científico publicado en 2015

Reduced hypoxia risk in a systemic sclerosis patient with interstitial lung disease after long-term pulmonary rehabilitation.

artículo científico publicado en 2011

Regulation of local and metastatic host-mediated anti-tumour mechanisms by L-selectin and intercellular adhesion molecule-1

scientific article published on 01 February 2006

Serum CXCL16 concentrations correlate with the extent of skin sclerosis in patients with systemic sclerosis

artículo científico publicado en 2009

Serum adhesion molecule levels as prognostic markers in patients with early systemic sclerosis: a multicentre, prospective, observational study.

artículo científico publicado en 2014

Serum chemokine and cytokine levels as indicators of disease activity in patients with systemic sclerosis

scientific article published on 04 November 2010

Serum levels of 8-isoprostane, a marker of oxidative stress, are elevated in patients with systemic sclerosis.

artículo científico publicado en 2006

Serum pulmonary and activation-regulated chemokine/CCL18 levels in patients with systemic sclerosis: a sensitive indicator of active pulmonary fibrosis

scientific article published on 01 September 2005

Skin sclerosis as a manifestation of POEMS syndrome.

artículo científico publicado en 2012

Successful treatment of acquired reactive perforating collagenosis with topical benzoyl peroxide: A possible therapeutic action underlying structural and metabolic turnover

artículo científico publicado en 2019

Successful treatment of recalcitrant subcorneal pustular dermatosis with oral nicotinamide

scientific article published on 12 June 2019

Successful treatment with oral minocycline in a case with a long-standing idiopathic atrophoderma of Pasini and Pierini: Histopathological comparison with the contralateral normal skin

artículo científico publicado en 2019

Successful treatment with sildenafil in systemic sclerosis patients with isolated pulmonary arterial hypertension: two case reports.

artículo científico publicado en 2005

Survey of single-nucleotide polymorphisms in the gene encoding human deoxyribonuclease I-like 2 producing loss of function potentially implicated in the pathogenesis of parakeratosis.

artículo científico publicado en 2017

TGF-β-mediated downregulation of microRNA-196a contributes to the constitutive upregulated type I collagen expression in scleroderma dermal fibroblasts

artículo científico publicado en 2012

The clinical characteristics of juvenile-onset systemic sclerosis in Japanese patients

article published in 2014

The clinical relevance of serum antinuclear antibodies in Japanese patients with systemic sclerosis.

artículo científico publicado en 2008

The differential role of L-selectin and ICAM-1 in Th1-type and Th2-type contact hypersensitivity.

artículo científico publicado en 2010

The loss of MCP-1 attenuates cutaneous ischemia-reperfusion injury in a mouse model of pressure ulcer

scientific article published on 24 January 2008

The roles of chemokines in leukocyte recruitment and fibrosis in systemic sclerosis

artículo científico publicado en 2008

The roles of chemokines in the development of systemic sclerosis.

artículo científico publicado en 2008

The wound/burn guidelines - 1: Wounds in general

artículo científico publicado en 2016

The wound/burn guidelines - 2: Guidelines for the diagnosis and treatment for pressure ulcers

artículo científico publicado en 2016

The wound/burn guidelines - 3: Guidelines for the diagnosis and treatment for diabetic ulcer/gangrene

artículo científico publicado en 2016

The wound/burn guidelines - 4: Guidelines for the management of skin ulcers associated with connective tissue disease/vasculitis.

artículo científico publicado en 2016

The wound/burn guidelines - 5: Guidelines for the management of lower leg ulcers/varicose veins

artículo científico publicado en 2016

The wound/burn guidelines - 6: Guidelines for the management of burns

artículo científico publicado en 2016

Transethnic meta-analysis identifies GSDMA and PRDM1 as susceptibility genes to systemic sclerosis.

artículo científico publicado en 2017

Tuberculosis-unrelated erythema induratum occurring after commencing tumor necrosis factor (TNF)-α antagonist therapy in a case with ulcerative colitis: A rare comorbidity interconnected by TNF-α blockade pathway

scientific article published on 19 July 2020

Two cases of livedo vasculopathy with non-criteria antiphospholipid antibodies

scientific article published on 14 September 2012

Two novel missense mutations of STS gene underlie X-linked recessive ichthyosis: understanding of the mutational and structural spectrum.

artículo científico publicado en 2015

Use of serum clara cell 16-kDa (CC16) levels as a potential indicator of active pulmonary fibrosis in systemic sclerosis

artículo científico publicado en 2011

Usefulness of anti-cyclic citrullinated peptide antibody and rheumatoid factor to detect rheumatoid arthritis in patients with systemic sclerosis

artículo científico publicado en 2010

Watermelon stomach and colon in a patient with diffuse cutaneous systemic sclerosis

artículo científico publicado en 2016

Wound, pressure ulcer and burn guidelines - 1: Guidelines for wounds in general, second edition

artículo científico publicado en 2020

Wound, pressure ulcer and burn guidelines - 2: Guidelines for the diagnosis and treatment of pressure ulcers, second edition

scientific article published on 08 September 2018

Wound, pressure ulcer and burn guidelines - 4: Guidelines for the management of connective tissue disease/vasculitis-associated skin ulcers

artículo científico publicado en 2020

Wound, pressure ulcer and burn guidelines - 6: Guidelines for the management of burns, second edition

artículo científico publicado en 2020