Lista de obras -

A pharmacological master key mechanism that unlocks the selectivity filter gate in K+ channels ⬇️

scientific article published on 01 February 2019

An extracellular cation coordination site influences ion conduction of OsHKT2;2

scientific article published on 15 July 2019

Chalcone derivatives as non-canonical ligands of TRPV1

scientific article published on 23 April 2019

Cloning and functional characterization of HKT1 and AKT1 genes of Fragaria spp.-Relationship to plant response to salt stress

artículo científico publicado en 2016

CoaTx-II, a new dimeric Lys49 phospholipase A2 from Crotalus oreganus abyssus snake venom with bactericidal potential: Insights into its structure and biological roles.

artículo científico publicado en 2016

Commandeering Channel Voltage Sensors for Secretion, Cell Turgor, and Volume Control

artículo científico publicado en 2016

Computational Studies of Snake Venom Toxins.

artículo científico publicado en 2017

Conotoxins as Tools to Understand the Physiological Function of Voltage-Gated Calcium (CaV) Channels.

artículo científico publicado en 2017

Corrigendum to “Exploring and understanding the functional role, and biochemical and structural characteristics of an acidic phospholipase A2, AplTx-I, purified from Agkistrodon piscivorus leucostoma snake venom” [Toxicon 127 (2017) 22–36]

artículo científico publicado en 2017

Cx46 hemichannel modulation by nitric oxide: Role of the fourth transmembrane helix cysteine and its possible involvement in cataract formation

artículo científico publicado en 2019

Discovery of Novel TASK-3 Channel Blockers Using a Pharmacophore-Based Virtual Screening

artículo científico publicado en 2019

Distinct roles of the last transmembrane domain in controlling Arabidopsis K+ channel activity.

artículo científico publicado en 2009

EB1- and EB2-dependent anterograde trafficking of TRPM4 regulates focal adhesion turnover and cell invasion

artículo científico publicado en 2019

Elucidating the Structural Basis of the Intracellular pH Sensing Mechanism of TASK-2 K2P Channels

artículo científico publicado en 2020

Exploring and understanding the functional role, and biochemical and structural characteristics of an acidic phospholipase A2, AplTx-I, purified from Agkistrodon piscivorus leucostoma snake venom.

artículo científico publicado en 2017

Exploring the fundamental role of potassium channels in novel model plants

artículo científico publicado en 2019

Folding and Lipid Composition Determine Membrane Interaction of the Disordered Protein COR15A

artículo científico publicado en 2018

Functional mutagenesis screens reveal the 'cap structure' formation in disulfide-bridge free TASK channels.

artículo científico publicado en 2016

Gap-junctional channel and hemichannel activity of two recently identified connexin 26 mutants associated with deafness.

artículo científico publicado en 2016

Gating of two-pore domain K+ channels by extracellular pH

artículo científico publicado en 2006

Identification of the A293 (AVE1231) Binding Site in the Cardiac Two-Pore-Domain Potassium Channel TASK-1: a Common Low Affinity Antiarrhythmic Drug Binding Site

artículo científico publicado en 2019

In silico analysis of the competition between Streptococcus sanguinis and Streptococcus mutans in the dental biofilm.

artículo científico publicado en 2017

Intrinsic electrostatic potential in the BK channel pore: role in determining single channel conductance and block.

artículo científico publicado en 2008

Kv1.5 blockers preferentially inhibit TASK-1 channels: TASK-1 as a target against atrial fibrillation and obstructive sleep apnea?

artículo científico publicado en 2014

K₂p channels in plants and animals.

artículo científico publicado en 2014

Molecular dynamics simulations and CD spectroscopy reveal hydration-induced unfolding of the intrinsically disordered LEA proteins COR15A and COR15B from Arabidopsis thaliana.

artículo científico publicado en 2016

Mutation Update of the CLCN5 Gene Responsible for Dent Disease 1.

artículo científico

Outward Rectification of Voltage-Gated K+ Channels Evolved at Least Twice in Life History

artículo científico publicado en 2015

Potassium (K+) gradients serve as a mobile energy source in plant vascular tissues.

artículo científico publicado en 2010

Side Fenestrations Provide an "Anchor" for a Stable Binding of A1899 to the Pore of TASK-1 Potassium Channels

artículo científico publicado en 2017

Sodium permeable and "hypersensitive" TREK-1 channels cause ventricular tachycardia.

artículo científico publicado en 2017

Structure/Activity Analysis of TASK-3 Channel Antagonists Based on a 5,6,7,8 tetrahydropyrido[4,3-d]pyrimidine ⬇️

artículo científico publicado en 2019

TASK Channels Pharmacology: New Challenges in Drug Design

scientific article published on 15 July 2019

TASK-2: a K2P K(+) channel with complex regulation and diverse physiological functions.

artículo científico publicado en 2013

TASK-3 Gene Knockdown Dampens Invasion and Migration and Promotes Apoptosis in KATO III and MKN-45 Human Gastric Adenocarcinoma Cell Lines

scientific article published on 02 December 2019

The K (+) battery-regulating Arabidopsis K (+) channel AKT2 is under the control of multiple post-translational steps

artículo científico publicado en 2011

The molecular basis for an allosteric inhibition of K-flux gating in K channels

artículo científico publicado en 2019

Voltage-sensor transitions of the inward-rectifying K+ channel KAT1 indicate a latching mechanism biased by hydration within the voltage sensor.

artículo científico publicado en 2014

Yeast strain Saccharomyces cerevisiae BYT45 lacking the cation extrusion systems ENA1-5 and NHA1 is suitable for the characterization of TASK-3 potassium channel antagonists

scientific article published on 01 August 2019

Lista de obras de

A pharmacological master key mechanism that unlocks the selectivity filter gate in K+ channels ⬇️

An extracellular cation coordination site influences ion conduction of OsHKT2;2

Chalcone derivatives as non-canonical ligands of TRPV1

Cloning and functional characterization of HKT1 and AKT1 genes of Fragaria spp.-Relationship to plant response to salt stress

CoaTx-II, a new dimeric Lys49 phospholipase A2 from Crotalus oreganus abyssus snake venom with bactericidal potential: Insights into its structure and biological roles.

Commandeering Channel Voltage Sensors for Secretion, Cell Turgor, and Volume Control

Computational Studies of Snake Venom Toxins.

Conotoxins as Tools to Understand the Physiological Function of Voltage-Gated Calcium (CaV) Channels.

Corrigendum to “Exploring and understanding the functional role, and biochemical and structural characteristics of an acidic phospholipase A2, AplTx-I, purified from Agkistrodon piscivorus leucostoma snake venom” [Toxicon 127 (2017) 22–36]

Cx46 hemichannel modulation by nitric oxide: Role of the fourth transmembrane helix cysteine and its possible involvement in cataract formation

Discovery of Novel TASK-3 Channel Blockers Using a Pharmacophore-Based Virtual Screening

Distinct roles of the last transmembrane domain in controlling Arabidopsis K+ channel activity.

EB1- and EB2-dependent anterograde trafficking of TRPM4 regulates focal adhesion turnover and cell invasion

Elucidating the Structural Basis of the Intracellular pH Sensing Mechanism of TASK-2 K2P Channels

Exploring and understanding the functional role, and biochemical and structural characteristics of an acidic phospholipase A2, AplTx-I, purified from Agkistrodon piscivorus leucostoma snake venom.

Exploring the fundamental role of potassium channels in novel model plants

Folding and Lipid Composition Determine Membrane Interaction of the Disordered Protein COR15A

Functional mutagenesis screens reveal the 'cap structure' formation in disulfide-bridge free TASK channels.

Gap-junctional channel and hemichannel activity of two recently identified connexin 26 mutants associated with deafness.

Gating of two-pore domain K+ channels by extracellular pH

Identification of the A293 (AVE1231) Binding Site in the Cardiac Two-Pore-Domain Potassium Channel TASK-1: a Common Low Affinity Antiarrhythmic Drug Binding Site

In silico analysis of the competition between Streptococcus sanguinis and Streptococcus mutans in the dental biofilm.

Intrinsic electrostatic potential in the BK channel pore: role in determining single channel conductance and block.

Kv1.5 blockers preferentially inhibit TASK-1 channels: TASK-1 as a target against atrial fibrillation and obstructive sleep apnea?

K₂p channels in plants and animals.

Molecular dynamics simulations and CD spectroscopy reveal hydration-induced unfolding of the intrinsically disordered LEA proteins COR15A and COR15B from Arabidopsis thaliana.

Mutation Update of the CLCN5 Gene Responsible for Dent Disease 1.

Outward Rectification of Voltage-Gated K+ Channels Evolved at Least Twice in Life History

Potassium (K+) gradients serve as a mobile energy source in plant vascular tissues.

Side Fenestrations Provide an "Anchor" for a Stable Binding of A1899 to the Pore of TASK-1 Potassium Channels

Sodium permeable and "hypersensitive" TREK-1 channels cause ventricular tachycardia.

Structure/Activity Analysis of TASK-3 Channel Antagonists Based on a 5,6,7,8 tetrahydropyrido[4,3-d]pyrimidine ⬇️

TASK Channels Pharmacology: New Challenges in Drug Design

TASK-2: a K2P K(+) channel with complex regulation and diverse physiological functions.

TASK-3 Gene Knockdown Dampens Invasion and Migration and Promotes Apoptosis in KATO III and MKN-45 Human Gastric Adenocarcinoma Cell Lines

The K (+) battery-regulating Arabidopsis K (+) channel AKT2 is under the control of multiple post-translational steps

The molecular basis for an allosteric inhibition of K-flux gating in K channels

Voltage-sensor transitions of the inward-rectifying K+ channel KAT1 indicate a latching mechanism biased by hydration within the voltage sensor.

Yeast strain Saccharomyces cerevisiae BYT45 lacking the cation extrusion systems ENA1-5 and NHA1 is suitable for the characterization of TASK-3 potassium channel antagonists