Lista de obras - Luca Agnelli - Dominio Público Uruguay

A SNP microarray and FISH-based procedure to detect allelic imbalances in multiple myeloma: an integrated genomics approach reveals a wide gene dosage effect

artículo científico publicado en 2009

A compendium of DIS3 mutations and associated transcriptional signatures in plasma cell dyscrasias.

artículo científico publicado en 2015

A compendium of long non-coding RNAs transcriptional fingerprint in multiple myeloma.

artículo científico publicado en 2018

B-cell receptor configuration and adverse cytogenetics are associated with autoimmune hemolytic anemia in chronic lymphocytic leukemia

artículo científico publicado en 2012

Biological and clinical relevance of miRNA expression signatures in primary plasma cell leukemia.

artículo científico publicado en 2013

Bone osteoblastic and mesenchymal stromal cells lack primarily tumoral features in multiple myeloma patients

artículo científico publicado en 2010

Characterization of oncogene dysregulation in multiple myeloma by combined FISH and DNA microarray analyses

artículo científico publicado en 2005

Chromosome 2p gain in monoclonal B-cell lymphocytosis and in early stage chronic lymphocytic leukemia.

artículo científico publicado en 2012

Correction: miR-451a is underexpressed and targets AKT/mTOR pathway in papillary thyroid carcinoma.

artículo científico publicado en 2018

Dependence on glutamine uptake and glutamine addiction characterize myeloma cells: a new attractive target.

artículo científico publicado en 2016

Disentangling the microRNA regulatory milieu in multiple myeloma: integrative genomics analysis outlines mixed miRNA-TF circuits and pathway-derived networks modulated in t(4;14) patients.

artículo científico publicado en 2015

Distinct lncRNA transcriptional fingerprints characterize progressive stages of multiple myeloma.

artículo científico publicado en 2016

Distinct patterns of global promoter methylation in early stage chronic lymphocytic leukemia

artículo científico publicado en 2013

Distinct transcriptional profiles characterize bone microenvironment mesenchymal cells rather than osteoblasts in relationship with multiple myeloma bone disease.

artículo científico publicado en 2009

Drugging the lncRNA MALAT1 via LNA gapmeR ASO inhibits gene expression of proteasome subunits and triggers anti-multiple myeloma activity.

artículo científico publicado en 2018

Expanding the repertoire of miRNAs and miRNA-offset RNAs expressed in multiple myeloma by small RNA deep sequencing

artículo científico publicado en 2019

Expression Pattern and Biological Significance of the lncRNA ST3GAL6-AS1 in Multiple Myeloma

artículo científico publicado en 2020

Functional validation of the anaplastic lymphoma kinase signature identifies CEBPB and BCL2A1 as critical target genes.

artículo científico publicado en 2006

Galectin-1 suppression delineates a new strategy to inhibit myeloma-induced angiogenesis and tumoral growth in vivo

artículo científico publicado en 2016

Gene expression profiling of plasma cell dyscrasias reveals molecular patterns associated with distinct IGH translocations in multiple myeloma

article

Gene expression profiling uncovers molecular classifiers for the recognition of anaplastic large-cell lymphoma within peripheral T-cell neoplasms

artículo científico publicado en 2010

Genome-wide analysis of primary plasma cell leukemia identifies recurrent imbalances associated with changes in transcriptional profiles

article

HOXB7 expression by myeloma cells regulates their pro-angiogenic properties in multiple myeloma patients.

artículo científico publicado en 2010

Hypoxia-inducible factor (HIF)-1α suppression in myeloma cells blocks tumoral growth in vivo inhibiting angiogenesis and bone destruction.

artículo científico publicado en 2013

IL21R expressing CD14+CD16+ monocytes expand in multiple myeloma patients leading to increased osteoclasts.

artículo científico publicado en 2017

Identification of a 3-gene model as a powerful diagnostic tool for the recognition of ALK-negative anaplastic large-cell lymphoma

artículo científico publicado en 2012

Identification of a new subclass of ALK-negative ALCL expressing aberrant levels of ERBB4 transcripts

artículo científico publicado en 2015

Identification of microRNA expression patterns and definition of a microRNA/mRNA regulatory network in distinct molecular groups of multiple myeloma.

artículo científico publicado en 2009

Identification of primary MAFB target genes in multiple myeloma.

artículo científico publicado en 2008

Immune thrombocytopenia in patients with chronic lymphocytic leukemia is associated with stereotyped B-cell receptors.

artículo científico publicado en 2012

Immunoreactivity for cyclin D1 is a reliable marker of gene aberration in plasma cell myeloma but does not specify patients prognosis

article

Impact of host genes and strand selection on miRNA and miRNA* expression.

artículo científico publicado en 2011

Improved risk stratification in myeloma using a microRNA-based classifier.

artículo científico publicado en 2013

In Silico Characterization of miRNA and Long Non-Coding RNA Interplay in Multiple Myeloma.

artículo científico publicado en 2016

Increased osteocyte death in multiple myeloma patients: role in myeloma-induced osteoclast formation.

artículo científico publicado en 2012

Integrated analysis of microRNAs, transcription factors and target genes expression discloses a specific molecular architecture of hyperdiploid multiple myeloma

artículo científico publicado en 2015

Integration of transcriptional and mutational data simplifies the stratification of peripheral T-cell lymphoma

artículo científico publicado en 2019

Integrative genomic analysis reveals distinct transcriptional and genetic features associated with chromosome 13 deletion in multiple myeloma

artículo científico publicado en 2007

Integrative genomics analyses reveal molecularly distinct subgroups of B-cell chronic lymphocytic leukemia patients with 13q14 deletion.

artículo científico publicado en 2010

Integrative high-resolution microarray analysis of human myeloma cell lines reveals deregulated miRNA expression associated with allelic imbalances and gene expression profiles.

artículo científico publicado en 2009

Long Non-Coding RNAs in Multiple Myeloma

artículo científico publicado en 2018

Long non-coding RNA NEAT1 shows high expression unrelated to molecular features and clinical outcome in multiple myeloma

artículo científico publicado en 2018

Long non-coding RNA NEAT1 targeting impairs the DNA repair machinery and triggers anti-tumor activity in multiple myeloma

scientific article published on 19 August 2019

Molecular Classification and Pharmacogenetics of Primary Plasma Cell Leukemia: An Initial Approach toward Precision Medicine

artículo científico publicado en 2015

Molecular and transcriptional characterization of 17p loss in B-cell chronic lymphocytic leukemia

artículo científico publicado en 2008

Molecular and transcriptional characterization of the novel 17p11.2-p12 amplicon in multiple myeloma.

artículo científico publicado en 2007

Molecular characterization of human multiple myeloma cell lines by integrative genomics: insights into the biology of the disease.

artículo científico publicado en 2007

Molecular classification of multiple myeloma: a distinct transcriptional profile characterizes patients expressing CCND1 and negative for 14q32 translocations.

artículo científico publicado en 2005

Molecular spectrum of BRAF, NRAS and KRAS gene mutations in plasma cell dyscrasias: implication for MEK-ERK pathway activation

artículo científico publicado en 2015

Myeloma Cells Deplete Bone Marrow Glutamine and Inhibit Osteoblast Differentiation Limiting Asparagine Availability

artículo científico publicado en 2020

Myeloma cells inhibit non-canonical wnt co-receptor ror2 expression in human bone marrow osteoprogenitor cells: effect of wnt5a/ror2 pathway activation on the osteogenic differentiation impairment induced by myeloma cells.

artículo científico publicado en 2012

NEAT1 Long Isoform Is Highly Expressed in Chronic Lymphocytic Leukemia Irrespectively of Cytogenetic Groups or Clinical Outcome

artículo científico publicado en 2020

Overexpression of HOXB7 and homeobox genes characterizes multiple myeloma patients lacking the major primary immunoglobulin heavy chain locus translocations

article

Relevance of Ras gene mutations in the context of the molecular heterogeneity of multiple myeloma.

artículo científico publicado en 2007

Rescue of Hippo coactivator YAP1 triggers DNA damage-induced apoptosis in hematological cancers.

artículo científico publicado en 2014

Small nucleolar RNAs as new biomarkers in chronic lymphocytic leukemia

artículo científico publicado en 2013

The expression pattern of small nucleolar and small Cajal body-specific RNAs characterizes distinct molecular subtypes of multiple myeloma.

artículo científico publicado en 2012

The proapoptotic effect of zoledronic acid is independent of either the bone microenvironment or the intrinsic resistance to bortezomib of myeloma cells and is enhanced by the combination with arsenic trioxide.

artículo científico publicado en 2010

Transcriptional characterization of a prospective series of primary plasma cell leukemia revealed signatures associated with tumor progression and poorer outcome.

artículo científico publicado en 2013

Transcriptional features of multiple myeloma patients with chromosome 1q gain

artículo científico publicado en 2007

Upregulation of translational machinery and distinct genetic subgroups characterise hyperdiploidy in multiple myeloma

artículo científico publicado en 2007

lncRNA profiling in early-stage chronic lymphocytic leukemia identifies transcriptional fingerprints with relevance in clinical outcome

artículo científico publicado en 2016

miR-451a is underexpressed and targets AKT/mTOR pathway in papillary thyroid carcinoma.

artículo científico

microRNAome Expression in Chronic Lymphocytic Leukemia: Comparison with Normal B-cell Subsets and Correlations with Prognostic and Clinical Parameters

scientific article published on 10 June 2014

Lista de obras de Luca Agnelli

A SNP microarray and FISH-based procedure to detect allelic imbalances in multiple myeloma: an integrated genomics approach reveals a wide gene dosage effect

A compendium of DIS3 mutations and associated transcriptional signatures in plasma cell dyscrasias.

A compendium of long non-coding RNAs transcriptional fingerprint in multiple myeloma.

B-cell receptor configuration and adverse cytogenetics are associated with autoimmune hemolytic anemia in chronic lymphocytic leukemia

Biological and clinical relevance of miRNA expression signatures in primary plasma cell leukemia.

Bone osteoblastic and mesenchymal stromal cells lack primarily tumoral features in multiple myeloma patients

Characterization of oncogene dysregulation in multiple myeloma by combined FISH and DNA microarray analyses

Chromosome 2p gain in monoclonal B-cell lymphocytosis and in early stage chronic lymphocytic leukemia.

Correction: miR-451a is underexpressed and targets AKT/mTOR pathway in papillary thyroid carcinoma.

Dependence on glutamine uptake and glutamine addiction characterize myeloma cells: a new attractive target.

Disentangling the microRNA regulatory milieu in multiple myeloma: integrative genomics analysis outlines mixed miRNA-TF circuits and pathway-derived networks modulated in t(4;14) patients.

Distinct lncRNA transcriptional fingerprints characterize progressive stages of multiple myeloma.

Distinct patterns of global promoter methylation in early stage chronic lymphocytic leukemia

Distinct transcriptional profiles characterize bone microenvironment mesenchymal cells rather than osteoblasts in relationship with multiple myeloma bone disease.

Drugging the lncRNA MALAT1 via LNA gapmeR ASO inhibits gene expression of proteasome subunits and triggers anti-multiple myeloma activity.

Expanding the repertoire of miRNAs and miRNA-offset RNAs expressed in multiple myeloma by small RNA deep sequencing

Expression Pattern and Biological Significance of the lncRNA ST3GAL6-AS1 in Multiple Myeloma

Functional validation of the anaplastic lymphoma kinase signature identifies CEBPB and BCL2A1 as critical target genes.

Galectin-1 suppression delineates a new strategy to inhibit myeloma-induced angiogenesis and tumoral growth in vivo

Gene expression profiling of plasma cell dyscrasias reveals molecular patterns associated with distinct IGH translocations in multiple myeloma

Gene expression profiling uncovers molecular classifiers for the recognition of anaplastic large-cell lymphoma within peripheral T-cell neoplasms

Genome-wide analysis of primary plasma cell leukemia identifies recurrent imbalances associated with changes in transcriptional profiles

HOXB7 expression by myeloma cells regulates their pro-angiogenic properties in multiple myeloma patients.

Hypoxia-inducible factor (HIF)-1α suppression in myeloma cells blocks tumoral growth in vivo inhibiting angiogenesis and bone destruction.

IL21R expressing CD14+CD16+ monocytes expand in multiple myeloma patients leading to increased osteoclasts.

Identification of a 3-gene model as a powerful diagnostic tool for the recognition of ALK-negative anaplastic large-cell lymphoma

Identification of a new subclass of ALK-negative ALCL expressing aberrant levels of ERBB4 transcripts

Identification of microRNA expression patterns and definition of a microRNA/mRNA regulatory network in distinct molecular groups of multiple myeloma.

Identification of primary MAFB target genes in multiple myeloma.

Immune thrombocytopenia in patients with chronic lymphocytic leukemia is associated with stereotyped B-cell receptors.

Immunoreactivity for cyclin D1 is a reliable marker of gene aberration in plasma cell myeloma but does not specify patients prognosis

Impact of host genes and strand selection on miRNA and miRNA* expression.

Improved risk stratification in myeloma using a microRNA-based classifier.

In Silico Characterization of miRNA and Long Non-Coding RNA Interplay in Multiple Myeloma.

Increased osteocyte death in multiple myeloma patients: role in myeloma-induced osteoclast formation.

Integrated analysis of microRNAs, transcription factors and target genes expression discloses a specific molecular architecture of hyperdiploid multiple myeloma

Integration of transcriptional and mutational data simplifies the stratification of peripheral T-cell lymphoma

Integrative genomic analysis reveals distinct transcriptional and genetic features associated with chromosome 13 deletion in multiple myeloma

Integrative genomics analyses reveal molecularly distinct subgroups of B-cell chronic lymphocytic leukemia patients with 13q14 deletion.

Integrative high-resolution microarray analysis of human myeloma cell lines reveals deregulated miRNA expression associated with allelic imbalances and gene expression profiles.

Long Non-Coding RNAs in Multiple Myeloma

Long non-coding RNA NEAT1 shows high expression unrelated to molecular features and clinical outcome in multiple myeloma

Long non-coding RNA NEAT1 targeting impairs the DNA repair machinery and triggers anti-tumor activity in multiple myeloma

Molecular Classification and Pharmacogenetics of Primary Plasma Cell Leukemia: An Initial Approach toward Precision Medicine

Molecular and transcriptional characterization of 17p loss in B-cell chronic lymphocytic leukemia

Molecular and transcriptional characterization of the novel 17p11.2-p12 amplicon in multiple myeloma.

Molecular characterization of human multiple myeloma cell lines by integrative genomics: insights into the biology of the disease.

Molecular classification of multiple myeloma: a distinct transcriptional profile characterizes patients expressing CCND1 and negative for 14q32 translocations.

Molecular spectrum of BRAF, NRAS and KRAS gene mutations in plasma cell dyscrasias: implication for MEK-ERK pathway activation

Myeloma Cells Deplete Bone Marrow Glutamine and Inhibit Osteoblast Differentiation Limiting Asparagine Availability

Myeloma cells inhibit non-canonical wnt co-receptor ror2 expression in human bone marrow osteoprogenitor cells: effect of wnt5a/ror2 pathway activation on the osteogenic differentiation impairment induced by myeloma cells.

NEAT1 Long Isoform Is Highly Expressed in Chronic Lymphocytic Leukemia Irrespectively of Cytogenetic Groups or Clinical Outcome

Overexpression of HOXB7 and homeobox genes characterizes multiple myeloma patients lacking the major primary immunoglobulin heavy chain locus translocations

Relevance of Ras gene mutations in the context of the molecular heterogeneity of multiple myeloma.

Rescue of Hippo coactivator YAP1 triggers DNA damage-induced apoptosis in hematological cancers.

Small nucleolar RNAs as new biomarkers in chronic lymphocytic leukemia

The expression pattern of small nucleolar and small Cajal body-specific RNAs characterizes distinct molecular subtypes of multiple myeloma.

The proapoptotic effect of zoledronic acid is independent of either the bone microenvironment or the intrinsic resistance to bortezomib of myeloma cells and is enhanced by the combination with arsenic trioxide.

Transcriptional characterization of a prospective series of primary plasma cell leukemia revealed signatures associated with tumor progression and poorer outcome.

Transcriptional features of multiple myeloma patients with chromosome 1q gain

Upregulation of translational machinery and distinct genetic subgroups characterise hyperdiploidy in multiple myeloma

lncRNA profiling in early-stage chronic lymphocytic leukemia identifies transcriptional fingerprints with relevance in clinical outcome

miR-451a is underexpressed and targets AKT/mTOR pathway in papillary thyroid carcinoma.

microRNAome Expression in Chronic Lymphocytic Leukemia: Comparison with Normal B-cell Subsets and Correlations with Prognostic and Clinical Parameters