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An engineered fatty acid synthase combined with a carboxylic acid reductase enables de novo production of 1-octanol in Saccharomyces cerevisiae.

artículo científico publicado en 2018

Analysis of the co-translational assembly of the fungal fatty acid synthase (FAS)

artículo científico publicado en 2020

Blue-light-triggered photorelease of active chemicals captured by the flavoprotein dodecin.

artículo científico publicado en 2009

Characterization of the Polyspecific Transferase of Murine Type I Fatty Acid Synthase (FAS) and Implications for Polyketide Synthase (PKS) Engineering

artículo científico publicado en 2018

Characterization of the small flavin-binding dodecin in the roseoflavin producer Streptomyces davawensis

artículo científico publicado en 2018

Comparative biochemical and structural analysis of the flavin-binding dodecins from Streptomyces davaonensis and Streptomyces coelicolor reveals striking differences with regard to multimerization

scientific article published on 01 October 2019

Cryo-EM structure of fatty acid synthase (FAS) from Rhodosporidium toruloides provides insights into the evolutionary development of fungal FAS.

artículo científico publicado en 2015

Crystallization and X-ray diffraction studies of a complete bacterial fatty-acid synthase type I

artículo científico publicado en 2015

Dodecin Is the Key Player in Flavin Homeostasis of Archaea

artículo científico publicado en 2009

Dodecin sequesters FAD in closed conformation from the aqueous solution.

artículo científico publicado en 2006

Electrochemical switching of the flavoprotein dodecin at gold surfaces modified by flavin-DNA hybrid linkers

artículo científico publicado en 2008

Engineering fatty acid synthases for directed polyketide production.

artículo científico publicado en 2017

Engineering fungal de novo fatty acid synthesis for short chain fatty acid production

artículo científico publicado en 2017

Engineering of Chimeric Polyketide Synthases Using SYNZIP Docking Domains

scientific article published on 11 February 2019

Engineering strategies for rational polyketide synthase design

artículo científico publicado en 2018

Expanding the product portfolio of fungal type I fatty acid synthases

artículo científico publicado en 2017

Expression, crystallization and crystallographic analysis of DegS, a stress sensor of the bacterial periplasm.

artículo científico publicado en 2004

Fatty Acid Biosynthesis: Chain-Length Regulation and Control

scientific article published on 27 June 2019

Flavin Storage and Sequestration by Mycobacterium tuberculosis Dodecin

artículo científico publicado en 2018

Fusing α and β subunits of the fungal fatty acid synthase leads to improved production of fatty acids

scientific article published on 17 June 2020

Mechanism of substrate shuttling by the acyl-carrier protein within the fatty acid mega-synthase

artículo científico publicado en 2010

Modular polyketide synthases (PKSs): a new model fits all?

artículo científico publicado en 2014

Multi-Ligand-Binding Flavoprotein Dodecin as a Key Element for Reversible Surface Modification in Nano-biotechnology

artículo científico publicado en 2015

Multimeric options for the auto-activation of the Saccharomyces cerevisiae FAS type I megasynthase

artículo científico publicado en 2009

Parameters affecting the X-ray dose absorbed by macromolecular crystals.

artículo científico publicado en 2005

Perspectives on the evolution, assembly and conformational dynamics of fatty acid synthase type I (FAS I) systems.

artículo científico

Probing the modularity of Megasynthases by rational engineering of a fatty acid synthase type I

artículo científico publicado en 2018

Protein denaturation at the air-water interface and how to prevent it

artículo científico publicado en 2019

Site-Specific Labelling of Multidomain Proteins by Amber Codon Suppression

artículo científico publicado en 2018

Solution Structure and Conformational Flexibility of a Polyketide Synthase Module

artículo científico publicado en 2021

Strategies in megasynthase engineering - fatty acid synthases (FAS) as model proteins

artículo científico publicado en 2017

Structural and biochemical characterization of a halophilic archaeal alkaline phosphatase

artículo científico publicado en 2010

Structure and conformational variability of the mycobacterium tuberculosis fatty acid synthase multienzyme complex

artículo científico publicado en 2013

Structure of the archaeal chemotaxis protein CheY in a domain-swapped dimeric conformation

artículo científico publicado en 2019

Substrate promiscuity of polyketide synthase enables production of tsetse fly attractants 3-ethylphenol and 3-propylphenol by engineering precursor supply in yeast

scientific article published on 19 June 2020

The Flavoprotein Dodecin as a Redox Probe for Electron Transfer through DNA

artículo científico publicado en 2013

The role of the iterative modules in polyketide synthase evolution

scientific article published on 14 April 2020

Type I fatty acid synthase trapped in the octanoyl-bound state

scientific article published on 01 February 2020