Lista de obras - Valeria Pittalà - Dominio Público Uruguay

(+)-Methyl (1R,2S)-2-{[4-(4-Chlorophenyl)-4-hydroxypiperidin-1-yl]methyl}-1-phenylcyclopropanecarboxylate [(+)-MR200] Derivatives as Potent and Selective Sigma Receptor Ligands: Stereochemistry and Pharmacological Properties

artículo científico publicado en 2017

3-Amino-1,4,5,6-tetrahydropyrrolo[3,4-c]pyrazoles: a new class of CDK2 inhibitors.

artículo científico publicado en 2005

3-Arylpiperazinylethyl-1H-pyrrolo[2,3-d]pyrimidine-2,4(3H,7H)-dione derivatives as novel, high-affinity and selective alpha(1)-adrenoceptor ligands.

artículo científico publicado en 2005

5-HT7 receptor ligands: recent developments and potential therapeutic applications.

artículo científico publicado en 2007

A facile synthesis of new 2-carboxamido-3-carboxythiophene and 4,5,6,7-tetrahydro-2-carboxamido-3-carboxythieno[2,3-c]pyridine derivatives as potential endothelin receptors ligands.

artículo científico publicado en 2005

A focus on heme oxygenase-1 (HO-1) inhibitors

artículo científico publicado en 2013

Analysis of mechanisms for memory enhancement using novel and potent 5-HT1A receptor ligands.

artículo científico publicado en 2015

Antioxidant activity and phenolic content of microwave-assisted Solanum melongena extracts

scientific article published on 09 February 2014

Antioxidant properties of hydroxycinnamic acids: a review of structure- activity relationships

artículo científico publicado en 2013

Antitumor properties of substituted (αE)-α-(1H-indol-3-ylmethylene)benzeneacetic acids or amides.

artículo científico publicado en 2013

Comprehensive data on a 2D-QSAR model for Heme Oxygenase isoform 1 inhibitors

artículo científico publicado en 2017

Curcumin⁻Copper Complex Nanoparticles for the Management of Triple-Negative Breast Cancer

artículo científico publicado en 2018

Design and synthesis of new homo and hetero bis-piperazinyl-1-propanone derivatives as 5-HT7R selective ligands over 5-HT1AR.

artículo científico publicado en 2016

Development of new HO-1 inhibitors by a thorough scaffold-hopping analysis

scientific article published on 27 August 2018

Effects of Novel Nitric Oxide-Releasing Molecules against Oxidative Stress on Retinal Pigmented Epithelial Cells

artículo científico publicado en 2017

Effects of Polyphenolic Derivatives on Heme Oxygenase-System in Metabolic Dysfunctions.

artículo científico publicado en 2017

Effects of novel hybrids of caffeic acid phenethyl ester and NSAIDs on experimental ocular inflammation.

artículo científico publicado en 2015

Evaluation of novel aryloxyalkyl derivatives of imidazole and 1,2,4-triazole as heme oxygenase-1 (HO-1) inhibitors and their antitumor properties.

artículo científico publicado en 2013

Heme Oxygenase Database (HemeOxDB) and QSAR Analysis of Isoform 1 Inhibitors.

artículo científico

Heme Oxygenase Inhibition Sensitizes Neuroblastoma Cells to Carfilzomib

artículo científico publicado en 2018

Heme Oxygenase-1 Inhibition Sensitizes Human Prostate Cancer Cells towards Glucose Deprivation and Metformin-Mediated Cell Death.

artículo científico publicado en 2019

Heme Oxygenase-2 (HO-2) as a therapeutic target: Activators and inhibitors

artículo científico publicado en 2019

Heme oxygenase-1: A new druggable target in the management of chronic and acute myeloid leukemia.

artículo científico publicado en 2017

High affinity ligands and potent antagonists for the α1D-adrenergic receptor. Novel 3,8-disubstituted [1]benzothieno[3,2-d]pyrimidine derivatives.

artículo científico publicado en 2014

Hyphenated 3D-QSAR statistical model-scaffold hopping analysis for the identification of potentially potent and selective sigma-2 receptor ligands

artículo científico publicado en 2017

Identification of potentially potent Heme Oxygenase-1 inhibitors through 3D-QSAR coupled to scaffold hopping analysis.

artículo científico publicado en 2018

Latest advances towards the discovery of 5-HT(7) receptor ligands

artículo científico publicado en 2011

New 1,2,3,9-tetrahydro-4H-carbazol-4-one derivatives: analogues of HEAT as ligands for the alpha1-adrenergic receptor subtypes.

artículo científico publicado en 2006

New Arylethanolimidazole Derivatives as HO-1 Inhibitors with Cytotoxicity against MCF-7 Breast Cancer Cells

scientific article published on 11 March 2020

New N- and O-arylpiperazinylalkyl pyrimidines and 2-methylquinazolines derivatives as 5-HT7 and 5-HT1A receptor ligands: Synthesis, structure-activity relationships, and molecular modeling studies

artículo científico publicado en 2016

New bifunctional antioxidant/σ1 agonist ligands: Preliminary chemico-physical and biological evaluation

artículo científico publicado en 2016

New pyrimido[5,4-b]indoles and [1]benzothieno[3,2-d]pyrimidines: high affinity ligands for the alpha(1)-adrenoceptor subtypes

artículo científico publicado en 2006

Nitric oxide-releasing nanoparticles improve doxorubicin anticancer activity

artículo científico publicado en 2018

Novel 4-phenylpiperidine-2,6-dione derivatives. Ligands for α₁-adrenoceptor subtypes.

artículo científico publicado en 2011

Novel Caffeic Acid Phenethyl Ester (Cape) Analogues as Inducers of Heme Oxygenase-1.

artículo científico publicado en 2017

Novel Heme Oxygenase-1 (HO-1) Inducers Based on Dimethyl Fumarate Structure

artículo científico publicado en 2020

Novel Sigma Receptor Ligand-Nitric Oxide Photodonors: Molecular Hybrids for Double-Targeted Antiproliferative Effect.

artículo científico publicado en 2017

Novel Sigma-1 receptor antagonists: from opioids to small molecules: what is new?

artículo científico publicado en 2017

Novel Structural Insight into Inhibitors of Heme Oxygenase-1 (HO-1) by New Imidazole-Based Compounds: Biochemical and In Vitro Anticancer Activity Evaluation

artículo científico publicado en 2018

Novel imidazole derivatives as heme oxygenase-1 (HO-1) and heme oxygenase-2 (HO-2) inhibitors and their cytotoxic activity in human-derived cancer cell lines.

artículo científico publicado en 2015

Novel inhibitors of nitric oxide synthase with antioxidant properties

artículo científico publicado en 2012

Nrf2 as regulator of innate immunity: A molecular Swiss army knife!

artículo científico publicado en 2017

Potholing of the hydrophobic heme oxygenase-1 western region for the search of potent and selective imidazole-based inhibitors

artículo científico publicado en 2018

Progress in the development of more effective and safer analgesics for pain management

artículo científico publicado en 2019

Progress in the development of selective heme oxygenase-1 inhibitors and their potential therapeutic application

scientific article published on 12 February 2019

Protective Effects of Caffeic Acid Phenethyl Ester (CAPE) and Novel Cape Analogue as Inducers of Heme Oxygenase-1 in Streptozotocin-Induced Type 1 Diabetic Rats

scientific article published on 17 May 2019

Recent advances in drug discovery of phototherapeutic non-porphyrinic anticancer agents.

artículo científico publicado en 2017

Role of the Nrf2/HO-1 axis in bronchopulmonary dysplasia and hyperoxic lung injuries.

artículo científico publicado en 2017

S2RSLDB: a comprehensive manually curated, internet-accessible database of the sigma-2 receptor selective ligands

artículo científico publicado en 2017

Serotonin 5-HT3 and 5-HT4 ligands: an update of medicinal chemistry research in the last few years.

artículo científico publicado en 2010

Structure–Activity Relationships and Therapeutic Potentials of 5-HT7 Receptor Ligands: An Update

artículo científico publicado en 2018

Structure–activity relationships and molecular modeling studies of novel arylpiperazinylalkyl 2-benzoxazolones and 2-benzothiazolones as 5-HT7 and 5-HT1A receptor ligands

artículo científico publicado en 2014

Synthesis and Experimental Validation of New Designed Heterocyclic Compounds with Antiproliferative Activity versus Breast Cancer Cell Lines MCF-7 and MDA-MB-231

scholarly article in Journal of Chemistry, 2017

Synthesis and Molecular Modelling Studies of New 1,3-Diaryl-5-Oxo-Proline Derivatives as Endothelin Receptor Ligands

scientific article published on 17 April 2020

Synthesis and binding properties of new long-chain 4-substituted piperazine derivatives as 5-HT₁A and 5-HT₇ receptor ligands

artículo científico publicado en 2015

Synthesis and endothelin receptor binding affinity of a novel class of 2-substituted-4-aryl-3-quinolinecarboxylic acid derivatives.

artículo científico publicado en 2008

Synthesis and endothelin receptors binding affinity of new 1,3,5- substituted pyrrole-2-carboxylic acid derivatives

artículo científico publicado en 2015

Synthesis and evaluation of haloperidol metabolite II prodrugs as anticancer agents.

artículo científico publicado en 2017

Synthesis and molecular modeling of 1H-pyrrolopyrimidine-2,4-dione derivatives as ligands for the α1-adrenoceptors

scientific article published on 21 June 2011

Synthesis of 1,2,4-triazole derivatives: binding properties on endothelin receptors.

artículo científico publicado en 2007

Synthesis of 3-arylpiperazinylalkylpyrrolo[3,2-d]pyrimidine-2,4-dione derivatives as novel, potent, and selective alpha1-adrenoceptor ligands.

artículo científico publicado en 2005

Synthesis of new arylpiperazinylalkylthiobenzimidazole, benzothiazole, or benzoxazole derivatives as potent and selective 5-HT1A serotonin receptor ligands.

artículo científico publicado en 2008

Synthesis, in vitro and in vivo characterization of new benzoxazole and benzothiazole-based sigma receptor ligands

scientific article published on 21 April 2019

Targeting STATs in neuroinflammation: The road less traveled!

scientific article published on 11 December 2018

Targeting heme Oxygenase-1 with hybrid compounds to overcome Imatinib resistance in chronic myeloid leukemia cell lines

scientific article published on 17 September 2018

The Effect of Silver Nanoparticles on Learning, Memory and Social Interaction in BALB/C Mice

artículo científico publicado en 2019

The International Natural Product Sciences Taskforce (INPST) and the power of Twitter networking exemplified through #INPST hashtag analysis

artículo científico publicado en 2023

Thieno[3,2-c]pyrazoles: a novel class of Aurora inhibitors with favorable antitumor activity

artículo científico publicado en 2010

[1]Benzothieno[3,2-d]pyrimidine derivatives as ligands for the serotonergic 5-HT7 receptor

artículo científico publicado en 2019

Lista de obras de Valeria Pittalà

(+)-Methyl (1R,2S)-2-{[4-(4-Chlorophenyl)-4-hydroxypiperidin-1-yl]methyl}-1-phenylcyclopropanecarboxylate [(+)-MR200] Derivatives as Potent and Selective Sigma Receptor Ligands: Stereochemistry and Pharmacological Properties

3-Amino-1,4,5,6-tetrahydropyrrolo[3,4-c]pyrazoles: a new class of CDK2 inhibitors.

3-Arylpiperazinylethyl-1H-pyrrolo[2,3-d]pyrimidine-2,4(3H,7H)-dione derivatives as novel, high-affinity and selective alpha(1)-adrenoceptor ligands.

5-HT7 receptor ligands: recent developments and potential therapeutic applications.

A facile synthesis of new 2-carboxamido-3-carboxythiophene and 4,5,6,7-tetrahydro-2-carboxamido-3-carboxythieno[2,3-c]pyridine derivatives as potential endothelin receptors ligands.

A focus on heme oxygenase-1 (HO-1) inhibitors

Analysis of mechanisms for memory enhancement using novel and potent 5-HT1A receptor ligands.

Antioxidant activity and phenolic content of microwave-assisted Solanum melongena extracts

Antioxidant properties of hydroxycinnamic acids: a review of structure- activity relationships

Antitumor properties of substituted (αE)-α-(1H-indol-3-ylmethylene)benzeneacetic acids or amides.

Comprehensive data on a 2D-QSAR model for Heme Oxygenase isoform 1 inhibitors

Curcumin⁻Copper Complex Nanoparticles for the Management of Triple-Negative Breast Cancer

Design and synthesis of new homo and hetero bis-piperazinyl-1-propanone derivatives as 5-HT7R selective ligands over 5-HT1AR.

Development of new HO-1 inhibitors by a thorough scaffold-hopping analysis

Effects of Novel Nitric Oxide-Releasing Molecules against Oxidative Stress on Retinal Pigmented Epithelial Cells

Effects of Polyphenolic Derivatives on Heme Oxygenase-System in Metabolic Dysfunctions.

Effects of novel hybrids of caffeic acid phenethyl ester and NSAIDs on experimental ocular inflammation.

Evaluation of novel aryloxyalkyl derivatives of imidazole and 1,2,4-triazole as heme oxygenase-1 (HO-1) inhibitors and their antitumor properties.

Heme Oxygenase Database (HemeOxDB) and QSAR Analysis of Isoform 1 Inhibitors.

Heme Oxygenase Inhibition Sensitizes Neuroblastoma Cells to Carfilzomib

Heme Oxygenase-1 Inhibition Sensitizes Human Prostate Cancer Cells towards Glucose Deprivation and Metformin-Mediated Cell Death.

Heme Oxygenase-2 (HO-2) as a therapeutic target: Activators and inhibitors

Heme oxygenase-1: A new druggable target in the management of chronic and acute myeloid leukemia.

High affinity ligands and potent antagonists for the α1D-adrenergic receptor. Novel 3,8-disubstituted [1]benzothieno[3,2-d]pyrimidine derivatives.

Hyphenated 3D-QSAR statistical model-scaffold hopping analysis for the identification of potentially potent and selective sigma-2 receptor ligands

Identification of potentially potent Heme Oxygenase-1 inhibitors through 3D-QSAR coupled to scaffold hopping analysis.

Latest advances towards the discovery of 5-HT(7) receptor ligands

New 1,2,3,9-tetrahydro-4H-carbazol-4-one derivatives: analogues of HEAT as ligands for the alpha1-adrenergic receptor subtypes.

New Arylethanolimidazole Derivatives as HO-1 Inhibitors with Cytotoxicity against MCF-7 Breast Cancer Cells

New N- and O-arylpiperazinylalkyl pyrimidines and 2-methylquinazolines derivatives as 5-HT7 and 5-HT1A receptor ligands: Synthesis, structure-activity relationships, and molecular modeling studies

New bifunctional antioxidant/σ1 agonist ligands: Preliminary chemico-physical and biological evaluation

New pyrimido[5,4-b]indoles and [1]benzothieno[3,2-d]pyrimidines: high affinity ligands for the alpha(1)-adrenoceptor subtypes

Nitric oxide-releasing nanoparticles improve doxorubicin anticancer activity

Novel 4-phenylpiperidine-2,6-dione derivatives. Ligands for α₁-adrenoceptor subtypes.

Novel Caffeic Acid Phenethyl Ester (Cape) Analogues as Inducers of Heme Oxygenase-1.

Novel Heme Oxygenase-1 (HO-1) Inducers Based on Dimethyl Fumarate Structure

Novel Sigma Receptor Ligand-Nitric Oxide Photodonors: Molecular Hybrids for Double-Targeted Antiproliferative Effect.

Novel Sigma-1 receptor antagonists: from opioids to small molecules: what is new?

Novel Structural Insight into Inhibitors of Heme Oxygenase-1 (HO-1) by New Imidazole-Based Compounds: Biochemical and In Vitro Anticancer Activity Evaluation

Novel imidazole derivatives as heme oxygenase-1 (HO-1) and heme oxygenase-2 (HO-2) inhibitors and their cytotoxic activity in human-derived cancer cell lines.

Novel inhibitors of nitric oxide synthase with antioxidant properties

Nrf2 as regulator of innate immunity: A molecular Swiss army knife!

Potholing of the hydrophobic heme oxygenase-1 western region for the search of potent and selective imidazole-based inhibitors

Progress in the development of more effective and safer analgesics for pain management

Progress in the development of selective heme oxygenase-1 inhibitors and their potential therapeutic application

Protective Effects of Caffeic Acid Phenethyl Ester (CAPE) and Novel Cape Analogue as Inducers of Heme Oxygenase-1 in Streptozotocin-Induced Type 1 Diabetic Rats

Recent advances in drug discovery of phototherapeutic non-porphyrinic anticancer agents.

Role of the Nrf2/HO-1 axis in bronchopulmonary dysplasia and hyperoxic lung injuries.

S2RSLDB: a comprehensive manually curated, internet-accessible database of the sigma-2 receptor selective ligands

Serotonin 5-HT3 and 5-HT4 ligands: an update of medicinal chemistry research in the last few years.

Structure–Activity Relationships and Therapeutic Potentials of 5-HT7 Receptor Ligands: An Update

Structure–activity relationships and molecular modeling studies of novel arylpiperazinylalkyl 2-benzoxazolones and 2-benzothiazolones as 5-HT7 and 5-HT1A receptor ligands

Synthesis and Experimental Validation of New Designed Heterocyclic Compounds with Antiproliferative Activity versus Breast Cancer Cell Lines MCF-7 and MDA-MB-231

Synthesis and Molecular Modelling Studies of New 1,3-Diaryl-5-Oxo-Proline Derivatives as Endothelin Receptor Ligands

Synthesis and binding properties of new long-chain 4-substituted piperazine derivatives as 5-HT₁A and 5-HT₇ receptor ligands

Synthesis and endothelin receptor binding affinity of a novel class of 2-substituted-4-aryl-3-quinolinecarboxylic acid derivatives.

Synthesis and endothelin receptors binding affinity of new 1,3,5- substituted pyrrole-2-carboxylic acid derivatives

Synthesis and evaluation of haloperidol metabolite II prodrugs as anticancer agents.

Synthesis and molecular modeling of 1H-pyrrolopyrimidine-2,4-dione derivatives as ligands for the α1-adrenoceptors

Synthesis of 1,2,4-triazole derivatives: binding properties on endothelin receptors.

Synthesis of 3-arylpiperazinylalkylpyrrolo[3,2-d]pyrimidine-2,4-dione derivatives as novel, potent, and selective alpha1-adrenoceptor ligands.

Synthesis of new arylpiperazinylalkylthiobenzimidazole, benzothiazole, or benzoxazole derivatives as potent and selective 5-HT1A serotonin receptor ligands.

Synthesis, in vitro and in vivo characterization of new benzoxazole and benzothiazole-based sigma receptor ligands

Targeting STATs in neuroinflammation: The road less traveled!

Targeting heme Oxygenase-1 with hybrid compounds to overcome Imatinib resistance in chronic myeloid leukemia cell lines

The Effect of Silver Nanoparticles on Learning, Memory and Social Interaction in BALB/C Mice

The International Natural Product Sciences Taskforce (INPST) and the power of Twitter networking exemplified through #INPST hashtag analysis

Thieno[3,2-c]pyrazoles: a novel class of Aurora inhibitors with favorable antitumor activity

[1]Benzothieno[3,2-d]pyrimidine derivatives as ligands for the serotonergic 5-HT7 receptor