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A new synthesis method and degradation of hyper-branched polyethylenimine grafted polycaprolactone block mono-methoxyl poly (ethylene glycol) copolymers (hy-PEI-g-PCL-b-mPEG) as potential DNA delivery vectors

artículo científico publicado en 2009

ABA-triblock copolymers from biodegradable polyester A-blocks and hydrophilic poly(ethylene oxide) B-blocks as a candidate for in situ forming hydrogel delivery systems for proteins ⬇️

artículo científico publicado el 17 de enero de 2002

Amine-modified hyperbranched polyesters as non-toxic, biodegradable gene delivery systems

artículo científico publicado en 2009

Amphiphilic and biodegradable hy-PEI-g-PCL-b-PEG copolymers efficiently mediate transgene expression depending on their graft density

artículo científico publicado en 2011

Amphiphilic biodegradable PEG-PCL-PEI triblock copolymers for FRET-capable in vitro and in vivo delivery of siRNA and quantum dots

artículo científico publicado en 2014

Amphiphilic, low molecular weight poly(ethylene imine) derivatives with enhanced stability for efficient pulmonary gene delivery

artículo científico publicado en 2011

Biodegradable capsules as non-viral vectors for in vitro delivery of PEI/siRNA polyplexes for efficient gene silencing

artículo científico publicado en 2014

Biodegradable poly(ethylene carbonate) nanoparticles as a promising drug delivery system with "stealth" potential

artículo científico publicado en 2011

Biodegradable polymeric nanocarriers for pulmonary drug delivery

scholarly article by Erik Rytting et al published June 2008 in Expert Opinion on Drug Delivery

Biodegradable polymers and their potential use in parenteral veterinary drug delivery systems

artículo científico publicado en 2004

Biophysical and transfection studies of an amine-modified poly(vinyl alcohol) for gene delivery

artículo científico publicado en 2005

Biophysical characterization of hyper-branched polyethylenimine-graft- polycaprolactone-block-mono-methoxyl-poly(ethylene glycol) copolymers (hy-PEI-PCL-mPEG) for siRNA delivery ⬇️

artículo científico publicado el 23 de abril de 2011

Bioreducible polymers with cell penetrating and endosome buffering functionality for gene delivery systems ⬇️

artículo científico publicado el 23 de febrero de 2011

Bioreversibly crosslinked polyplexes of PEI and high molecular weight PEG show extended circulation times in vivo

artículo científico publicado en 2007

Branched polyesters based on poly[vinyl-3-(dialkylamino)alkylcarbamate-co-vinyl acetate-co-vinyl alcohol]-graft-poly(D,L-lactide-co-glycolide): effects of polymer structure on in vitro degradation behaviour

artículo científico publicado en 2008

Cellular uptake mechanism and knockdown activity of siRNA-loaded biodegradable DEAPA-PVA-g-PLGA nanoparticles ⬇️

artículo científico publicado el 10 de noviembre de 2011

Characterization and in vitro degradation of poly(2,3-(1,4-diethyl tartrate)-co-2,3-isopropyliden tartrate).

artículo científico publicado en 2004

Characterization of a homologous series of D,L-lactic acid oligomers; a mechanistic study on the degradation kinetics in vitro

artículo científico publicado en 2003

Characterization of novel spray-dried polymeric particles for controlled pulmonary drug delivery

artículo científico publicado en 2011

Chitosan-based formulations for delivery of DNA and siRNA.

artículo científico publicado en 2009

Coating of poly(p-xylylene) by PLA-PEO-PLA triblock copolymers with excellent polymer-polymer adhesion for stent applications

artículo científico publicado en 2006

Comparative in vivo study of poly(ethylene imine)/siRNA complexes for pulmonary delivery in mice

artículo científico publicado en 2011

Comparative uptake studies of bioadhesive and non-bioadhesive nanoparticles in human intestinal cell lines and rats: the effect of mucus on particle adsorption and transport.

artículo científico publicado en 2002

Computational insights into the interactions between DNA and siRNA with "rigid" and "flexible" triazine dendrimers

artículo científico publicado en 2010

Controlled pulmonary drug and gene delivery using polymeric nano-carriers ⬇️

artículo científico publicado el 13 de diciembre de 2011

Controlled release of gentamicin from calcium phosphate-poly(lactic acid-co-glycolic acid) composite bone cement

artículo científico publicado en 2006

Copolymers of ethylene imine and N-(2-hydroxyethyl)-ethylene imine as tools to study effects of polymer structure on physicochemical and biological properties of DNA complexes

artículo científico publicado en 2002

Core-cross-linked polymeric micelles as paclitaxel carriers

artículo científico publicado en 2004

Crosslinked nanocarriers based upon poly(ethylene imine) for systemic plasmid delivery: in vitro characterization and in vivo studies in mice

artículo científico publicado en 2007

DNA nano-carriers from biodegradable cationic branched polyesters are formed by a modified solvent displacement method

artículo científico publicado en 2006

Delivery of messenger RNA using poly(ethylene imine)–poly(ethylene glycol)-copolymer blends for polyplex formation: Biophysical characterization and in vitro transfection properties ⬇️

artículo científico publicado el 18 de septiembre de 2010

Deposition of nanoparticles in the arterial vessel by porous balloon catheters: localization by confocal laser scanning microscopy and transmission electron microscopy.

artículo científico publicado en 2002

Design and biophysical characterization of bioresponsive degradable poly(dimethylaminoethyl methacrylate) based polymers for in vitro DNA transfection

artículo científico publicado en 2012

Design of amine-modified graft polyesters for effective gene delivery using DNA-loaded nanoparticles

artículo científico publicado en 2004

Development of a biodegradable nanoparticle platform for sildenafil: formulation optimization by factorial design analysis combined with application of charge-modified branched polyesters

artículo científico publicado en 2011

Development of a delivery system for the continuous endogenous release of an anti-idiotypic antibody against ovarian carcinoma

artículo científico publicado en 2005

Distribution and quantification of polyethylenimine oligodeoxynucleotide complexes in human skin after iontophoretic delivery using confocal scanning laser microscopy.

artículo científico publicado en 2002

Do cell culture conditions influence the carrier-mediated transport of peptides in Caco-2 cell monolayers?

artículo científico publicado en 2003

Drug eluting stents based on Poly(ethylene carbonate): optimization of the stent coating process

artículo científico publicado en 2011

Effect of PEGylation on the stability of liposomes during nebulisation and in lung surfactant

artículo científico publicado en 2006

Effect of WOW process parameters on morphology and burst release of FITC-dextran loaded PLGA microspheres

artículo científico publicado en 2006

Effect of chitosan structure properties and molecular weight on the intranasal absorption of tetramethylpyrazine phosphate in rats

artículo científico publicado en 2008

Effect of poly(ethylene imine) molecular weight and pegylation on organ distribution and pharmacokinetics of polyplexes with oligodeoxynucleotides in mice.

artículo científico publicado en 2004

Effects of cell-penetrating peptides and pegylation on transfection efficiency of polyethylenimine in mouse lungs

artículo científico publicado en 2008

Effects of different application parameters on penetration characteristics and arterial vessel wall integrity after local nanoparticle delivery using a porous balloon catheter

artículo científico publicado en 2004

Effects of process and formulation parameters on characteristics and internal morphology of poly(d,l-lactide-co-glycolide) microspheres formed by the solvent evaporation method

artículo científico publicado en 2007

Efficiency of polyethylenimines and polyethylenimine-graft-poly (ethylene glycol) block copolymers to protect oligonucleotides against enzymatic degradation

artículo científico publicado en 2004

Efficient and Tumor Targeted siRNA Delivery by Polyethylenimine-graft-polycaprolactone-block-poly(ethylene glycol)-folate (PEI-PCL-PEG-Fol).

artículo científico publicado en 2015

Enhanced gene expression and reduced toxicity in mice using polyplexes of low-molecular-weight poly(ethylene imine) for pulmonary gene delivery

artículo científico publicado en 2009

Enhancing in vivo circulation and siRNA delivery with biodegradable polyethylenimine-graft-polycaprolactone-block-poly(ethylene glycol) copolymers ⬇️

artículo científico publicado el 16 de junio de 2012

Enzyme-responsive surface erosion of poly(ethylene carbonate) for controlled drug release ⬇️

artículo científico publicado el 30 de abril de 2013

Factors influencing polycation/siRNA colloidal stability toward aerosol lung delivery

artículo científico publicado en 2011

Fast degrading polyesters as siRNA nano-carriers for pulmonary gene therapy

artículo científico publicado en 2008

Feasibility of macrophage mediated on-demand drug release from surface eroding poly(ethylene carbonate).

artículo científico publicado en 2014

Folic Acid‐Decorated Nanocomposites Prepared by a Simple Solvent Displacement Method ⬇️

artículo científico publicado el 20 de febrero de 2012

Functionalized polyglycerol amine nanogels as nanocarriers for DNA.

artículo científico publicado en 2014

Galactose-PEI-DNA complexes for targeted gene delivery: degree of substitution affects complex size and transfection efficiency

artículo científico publicado en 2003

HER2 targeted polyplexes: the effect of polyplex composition and conjugation chemistry on in vitro and in vivo characteristics

artículo científico publicado en 2007

Hydrolytic degradation of poly(lactide-co-glycolide) films: effect of oligomers on degradation rate and crystallinity ⬇️

artículo científico publicado el 6 de noviembre de 2003

Iloprost-containing liposomes for aerosol application in pulmonary arterial hypertension: formulation aspects and stability

artículo científico publicado en 2006

Imidazole and dimethyl aminopropyl-functionalized hyperbranched polymers for nucleic acid transfection

artículo científico publicado en 2010

Impact of lyoprotectants for the stabilization of biodegradable nanoparticles on the performance of air-jet, ultrasonic, and vibrating-mesh nebulizers.

artículo científico publicado en 2012

In situ forming nimodipine depot system based on microparticles for the treatment of posthemorrhagic cerebral vasospasm ⬇️

artículo científico publicado el 5 de enero de 2013

In situ forming parenteral depot systems based on poly(ethylene carbonate): Effect of polymer molecular weight on model protein release ⬇️

artículo científico publicado el 19 de junio de 2013

In vitro and in vivo correlation of buserelin release from biodegradable implants using statistical moment analysis

artículo científico publicado en 2004

In vitro and in vivo performance of biocompatible negatively-charged salbutamol-loaded nanoparticles

artículo científico publicado en 2009

In vitro cytotoxic and immunomodulatory profiling of low molecular weight polyethylenimines for pulmonary application

artículo científico publicado en 2009

In vitro cytotoxicity testing of polycations: influence of polymer structure on cell viability and hemolysis

artículo científico publicado en 2003

In vivo SPECT and real-time gamma camera imaging of biodistribution and pharmacokinetics of siRNA delivery using an optimized radiolabeling and purification procedure

artículo científico publicado en 2009

In vivo pharmacokinetics, tissue distribution and underlying mechanisms of various PEI(-PEG)/siRNA complexes

artículo científico publicado en 2009

Influence of amine-modified poly(vinyl alcohol)s on vibrating-membrane nebulizer performance and lung toxicity

artículo científico publicado en 2016

Influence of morphology and drug distribution on the release process of FITC-dextran-loaded microspheres prepared with different types of PLGA.

artículo científico publicado en 2008

Influence of particle size and material properties on mucociliary clearance from the airways

scientific article published on August 2010

Influence of polyethylene glycol chain length on the physicochemical and biological properties of poly(ethylene imine)-graft-poly(ethylene glycol) block copolymer/SiRNA polyplexes

artículo científico publicado en 2006

Insulin containing nanocomplexes formed by self-assembly from biodegradable amine-modified poly(vinyl alcohol)-graft-poly(L-lactide): bioavailability and nasal tolerability in rats

artículo científico publicado en 2005

Integrin alphaVbeta3 targeted gene delivery using RGD peptidomimetic conjugates with copolymers of PEGylated poly(ethylene imine).

artículo científico publicado en 2009

Integrin targeting using RGD-PEI conjugates for in vitro gene transfer

artículo científico publicado en 2003

Intracellular processing of poly(ethylene imine)/ribozyme complexes can be observed in living cells by using confocal laser scanning microscopy and inhibitor experiments

artículo científico publicado en 2002

Loading of tetanus toxoid to biodegradable nanoparticles from branched poly(sulfobutyl-polyvinyl alcohol)-g-(lactide-co-glycolide) nanoparticles by protein adsorption: a mechanistic study

artículo científico publicado en 2002

Low Molecular Weight pDMAEMA-block-pHEMA Block-Copolymers Synthesized via RAFT-Polymerization: Potential Non-Viral Gene Delivery Agents?

artículo científico publicado en 2011

Low molecular weight chitosan nanoparticles as new carriers for nasal vaccine delivery in mice

artículo científico publicado en 2004

Low-molecular-weight polyethylenimine as a non-viral vector for DNA delivery: comparison of physicochemical properties, transfection efficiency and in vivo distribution with high-molecular-weight polyethylenimine

artículo científico publicado en 2003

Lyophilised ready-to-use formulations of PEG-PCL-PEI nano-carriers for siRNA delivery

artículo científico publicado en 2012

Modular synthesis of folate conjugated ternary copolymers: polyethylenimine-graft-polycaprolactone-block-poly(ethylene glycol)-folate for targeted gene delivery

artículo científico publicado en 2012

Molecular modeling and in vivo imaging can identify successful flexible triazine dendrimer-based siRNA delivery systems

artículo científico publicado en 2011

Nanocomposites of lung surfactant and biodegradable cationic nanoparticles improve transfection efficiency to lung cells

artículo científico publicado en 2009

Nanofibers by green electrospinning of aqueous suspensions of biodegradable block copolyesters for applications in medicine, pharmacy and agriculture

artículo científico publicado en 2010

Nanoparticles for paclitaxel delivery: A comparative study of different types of dendritic polyesters and their degradation behavior ⬇️

artículo científico publicado el 21 de enero de 2011

Nanosized insulin-complexes based on biodegradable amine-modified graft polyesters poly[vinyl-3-(diethylamino)-propylcarbamate-co-(vinyl acetate)-co-(vinyl alcohol)]-graft-poly(L-lactic acid): protection against enzymatic degradation, interaction wi

artículo científico publicado en 2006

Nasal absorption and local tissue reaction of insulin nanocomplexes of trimethyl chitosan derivatives in rats

artículo científico publicado en 2010

Nebulization of biodegradable nanoparticles: impact of nebulizer technology and nanoparticle characteristics on aerosol features

artículo científico publicado en 2003

Nebulization performance of biodegradable sildenafil-loaded nanoparticles using the Aeroneb Pro: formulation aspects and nanoparticle stability to nebulization

artículo científico publicado en 2011

Non-ionic dendritic glycerol-based amphiphiles: novel excipients for the solubilization of poorly water-soluble anticancer drug Sagopilone

artículo científico publicado en 2010

Nonviral pulmonary delivery of siRNA.

artículo científico publicado en 2011

Nonviral siRNA delivery to the lung: investigation of PEG-PEI polyplexes and their in vivo performance

artículo científico publicado en 2009

Novel 'nano in nano' composites for sustained drug delivery: biodegradable nanoparticles encapsulated into nanofiber non-wovens

artículo científico publicado en 2010

Novel magnetic iron oxide nanoparticles coated with poly(ethylene imine)-g-poly(ethylene glycol) for potential biomedical application: Synthesis, stability, cytotoxicity and MR imaging ⬇️

artículo científico publicado el 18 de febrero de 2011

Optimising the self-assembly of siRNA loaded PEG-PCL-lPEI nano-carriers employing different preparation techniques ⬇️

artículo científico publicado el 13 de abril de 2012

Optimized preparation of pDNA/poly(ethylene imine) polyplexes using a microfluidic system

artículo científico publicado en 2012

PEGylated poly(ethylene imine) copolymer-delivered siRNA inhibits HIV replication in vitro

artículo científico publicado en 2011

PEGylation affects cytotoxicity and cell-compatibility of poly(ethylene imine) for lung application: structure-function relationships

artículo científico publicado en 2009

PEGylation of poly(ethylene imine) affects stability of complexes with plasmid DNA under in vivo conditions in a dose-dependent manner after intravenous injection into mice

artículo científico publicado en 2005

Paclitaxel releasing films consisting of poly(vinyl alcohol)-graft-poly(lactide-co-glycolide) and their potential as biodegradable stent coatings

artículo científico publicado en 2006

Pegylated polyethylenimine-Fab' antibody fragment conjugates for targeted gene delivery to human ovarian carcinoma cells.

artículo científico publicado en 2003

Perfectly shaped siRNA delivery

artículo científico publicado en 2010

Peroral delivery of insulin using chitosan derivatives: a comparative study of polyelectrolyte nanocomplexes and nanoparticles

artículo científico publicado en 2007

Pharmaceutical care for patients with ischemic stroke: improving the patients quality of life

artículo científico publicado en 2009

Physicochemical and biological characterization of polyethylenimine-graft-poly(ethylene glycol) block copolymers as a delivery system for oligonucleotides and ribozymes

artículo científico publicado en 2004

Physicochemical properties and biocompatibility of N-trimethyl chitosan: effect of quaternization and dimethylation

artículo científico publicado en 2008

Poly(diallyldimethylammonium chlorides) and their N-methyl-N-vinylacetamide copolymer-based DNA-polyplexes: role of molecular weight and charge density in complex formation, stability, and in vitro activity

artículo científico publicado en 2004

Poly(ethylene carbonate) as a surface-eroding biomaterial for in situ forming parenteral drug delivery systems: a feasibility study

artículo científico publicado en 2010

Poly(ethylene imine) nanocarriers do not induce mutations nor oxidative DNA damage in vitro in MutaMouse FE1 cells

artículo científico publicado en 2011

Poly(ethylenimine-co-L-lactamide-co-succinamide): a biodegradable polyethylenimine derivative with an advantageous pH-dependent hydrolytic degradation for gene delivery

artículo científico publicado en 2002

Poly(vinyl alcohol) nanofibers by electrospinning as a protein delivery system and the retardation of enzyme release by additional polymer coatings

artículo científico publicado en 2005

Poly(vinyl alcohol)-graft-poly(lactide-co-glycolide) nanoparticles for local delivery of paclitaxel for restenosis treatment

artículo científico publicado en 2007

Polycationic triazine-based dendrimers: effect of peripheral groups on transfection efficiency

artículo científico publicado en 2009

Polyethylenimine-graft-poly(ethylene glycol) copolymers: influence of copolymer block structure on DNA complexation and biological activities as gene delivery system

artículo científico publicado en 2002

Polyfluorene nanoparticles coated with folate-functionalized triblock copolymer: effective agents for targeted cell imaging

artículo científico publicado en 2012

Polymer nanoparticle-based controlled pulmonary drug delivery

artículo científico publicado en 2014

Polymeric micelles for parenteral delivery of sagopilone: physicochemical characterization, novel formulation approaches and their toxicity assessment in vitro as well as in vivo

artículo científico publicado en 2010

Potential of the isolated lung technique for the examination of sildenafil absorption from lung-delivered poly(lactide-co-glycolide) microparticles

artículo científico publicado en 2016

Predicting protein instability in sustained protein delivery systems using spectral-phase interference ⬇️

artículo científico publicado el 2 de diciembre de 2011

Preparation of nanoparticles by solvent displacement for drug delivery: a shift in the "ouzo region" upon drug loading

artículo científico publicado en 2010

Prolonged vasodilatory response to nanoencapsulated sildenafil in pulmonary hypertension

artículo científico publicado en 2015

Prospects for cationic polymers in gene and oligonucleotide therapy against cancer

artículo científico publicado en 2002

Pulmonary drug delivery with aerosolizable nanoparticles in an ex vivo lung model

artículo científico publicado en 2008

Pulmonary gene delivery using polymeric nonviral vectors

artículo científico publicado en 2011

Pulmonary targeting with biodegradable salbutamol-loaded nanoparticles

artículo científico publicado en 2010

Quo vadis polyplex?

artículo científico publicado en 2014

Recent advances in rational gene transfer vector design based on poly(ethylene imine) and its derivatives

artículo científico publicado en 2005

Reflectance infrared spectroscopy for in-line monitoring of nicotine during a coating process for an oral thin film.

artículo científico publicado en 2013

Self-assembled polyelectrolyte nanocomplexes between chitosan derivatives and enoxaparin

artículo científico publicado en 2008

Self-assembled polyelectrolyte nanocomplexes between chitosan derivatives and insulin

artículo científico publicado en 2006

Solubilization of sagopilone, a poorly water-soluble anticancer drug, using polymeric micelles for parenteral delivery

artículo científico publicado en 2010

Stability of siRNA polyplexes from poly(ethylenimine) and poly(ethylenimine)-g-poly(ethylene glycol) under in vivo conditions: effects on pharmacokinetics and biodistribution measured by Fluorescence Fluctuation Spectroscopy and Single Photon Emissi

artículo científico publicado en 2009

Stabilization of aerosolizable nano-carriers by freeze-drying

artículo científico publicado en 2008

Stabilization of oligonucleotide-polyethylenimine complexes by freeze-drying: physicochemical and biological characterization

artículo científico publicado en 2004

Star-shaped poly(ethylene glycol)-block-polyethylenimine copolymers enhance DNA condensation of low molecular weight polyethylenimines.

artículo científico publicado en 2002

Supramolecular gene delivery vectors showing enhanced transgene expression and good biocompatibility

artículo científico publicado en 2005

Surfactant-free redispersible nanoparticles in fast-dissolving composite microcarriers for dry-powder inhalation ⬇️

artículo científico publicado el 7 de diciembre de 2010

Synthesis of a new potential biodegradable disulfide containing poly(ethylene imine)–poly(ethylene glycol) copolymer cross-linked with click cluster for gene delivery ⬇️

artículo científico publicado el 23 de marzo de 2011

Synthesis, characterization and cytotoxicity of poly(ethylene glycol)-graft-trimethyl chitosan block copolymers

artículo científico publicado en 2005

Targeting the blind spot of polycationic nanocarrier-based siRNA delivery

artículo científico publicado en 2012

Tetanus toxoid microspheres consisting of biodegradable poly(lactide-co-glycolide)- and ABA-triblock-copolymers: immune response in mice

artículo científico publicado en 2002

The Macrostopper Route: A New Synthesis Concept Leading Exclusively to Diblock Copolymers with Enhanced DNA Condensation Potential

The depolymerization of chitosan: effects on physicochemical and biological properties

artículo científico publicado en 2004

The potential of glycol chitosan nanoparticles as carrier for low water soluble drugs

artículo científico publicado en 2009

The role of branched polyesters and their modifications in the development of modern drug delivery vehicles

artículo científico publicado en 2005

The role of mucoadhesion of trimethyl chitosan and PEGylated trimethyl chitosan nanocomplexes in insulin uptake

artículo científico publicado en 2009

The structure of PEG-modified poly(ethylene imines) influences biodistribution and pharmacokinetics of their complexes with NF-kappaB decoy in mice

scientific article published on 01 June 2002

Toxicity pathway focused gene expression profiling of PEI-based polymers for pulmonary applications

artículo científico publicado en 2010

Triazine Dendrimers for DNA and siRNA Delivery: Progress, Challenges, and Opportunities

artículo científico publicado en 2012

Triazine dendrimers as nonviral gene delivery systems: effects of molecular structure on biological activity

artículo científico publicado en 2009

Triazine dendrimers as nonviral vectors for in vitro and in vivo RNAi: the effects of peripheral groups and core structure on biological activity

artículo científico publicado en 2010

Uptake and transport of PEG-graft-trimethyl-chitosan copolymer-insulin nanocomplexes by epithelial cells

artículo científico publicado en 2005

Variation of peptide transporter (PepT1 and HPT1) expression in Caco-2 cells as a function of cell origin

artículo científico publicado en 2004

siRNA delivery to the lung: what's new?

artículo científico publicado en 2014

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