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Cross‐talk between DNA methylation and active histone modifications regulates aberrant expression of ZAP70 in CLL

artículo científico publicado el 1 de septiembre de 2012

Curcumin induces high levels of topoisomerase I- and II-DNA complexes in K562 leukemia cells.

artículo científico publicado en 2007

DNA-dependent protein kinase is a therapeutic target and an indicator of poor prognosis in B-cell chronic lymphocytic leukemia.

artículo científico publicado en 2008

Differences in the longevity of topo IIalpha and topo IIbeta drug-stabilized cleavable complexes and the relationship to drug sensitivity.

artículo científico publicado en 2003

Etoposide Targets Topoisomerase IIα and IIβ in Leukemic Cells: Isoform-Specific Cleavable Complexes Visualized and QuantifiedIn Situby a Novel Immunofluorescence Technique

artículo científico publicado el 1 de julio de 1998

Identification of dual DNA-PK MDR1 inhibitors for the potentiation of cytotoxic drug activity.

artículo científico publicado en 2014

NF-κB mediates radio-sensitization by the PARP-1 inhibitor, AG-014699.

artículo científico

PARP1 expression, activity and ex vivo sensitivity to the PARP inhibitor, talazoparib (BMN 673), in chronic lymphocytic leukaemia.

artículo científico publicado en 2015

Preferential potentiation of topoisomerase I poison cytotoxicity by PARP inhibition in S phase.

artículo científico publicado en 2014

Regulation of p53 and Rb links the alternative NF-κB pathway to EZH2 expression and cell senescence.

artículo científico publicado en 2014

SKP2 is a direct transcriptional target of MYCN and a potential therapeutic target in neuroblastoma

artículo científico publicado en 2015

Selenite induces topoisomerase I and II-DNA complexes in K562 leukemia cells

scientific article published on 01 November 2008

The novel poly(ADP-Ribose) polymerase inhibitor, AG14361, sensitizes cells to topoisomerase I poisons by increasing the persistence of DNA strand breaks.

artículo científico publicado en 2005