Lista de obras -

A mitochondrial enzyme degrades carotenoids and protects against oxidative stress

artículo científico publicado en 2011

A mutation in the silver gene leads to defects in melanosome biogenesis and alterations in the visual system in the zebrafish mutant fading vision

artículo científico publicado en 2005

Activation of retinoic acid receptors by dihydroretinoids

artículo científico publicado en 2009

Analysis of Carotenoid Isomerase Activity in a Prototypical Carotenoid Cleavage Enzyme, Apocarotenoid Oxygenase (ACO)

artículo científico publicado en 2014

BCDO2 acts as a carotenoid scavenger and gatekeeper for the mitochondrial apoptotic pathway

artículo científico publicado en 2012

Beta,beta-carotene decreases peroxisome proliferator receptor gamma activity and reduces lipid storage capacity of adipocytes in a beta,beta-carotene oxygenase 1-dependent manner

artículo científico publicado en 2010

Carotenoid oxygenases: cleave it or leave it.

artículo científico publicado en 2003

Carotenoids

artículo científico publicado en 2013

Characterization of human β,β-carotene-15,15'-monooxygenase (BCMO1) as a soluble monomeric enzyme

artículo científico publicado en 2013

Characterization of the Role of β-Carotene 9,10-Dioxygenase in Macular Pigment Metabolism

artículo científico publicado en 2015

Colors with functions: elucidating the biochemical and molecular basis of carotenoid metabolism

artículo científico publicado en 2010

Conversion of beta-carotene to retinal pigment

artículo científico publicado en 2007

Diabetes-induced impairment in visual function in mice: contributions of p38 MAPK, rage, leukocytes, and aldose reductase

artículo científico publicado en 2014

Dietary 9-cis-β,β-carotene fails to rescue vision in mouse models of leber congenital amaurosis

artículo científico publicado en 2011

Differential expression of the demosponge (Suberites domuncula) carotenoid oxygenases in response to light: protection mechanism against the self-produced toxic protein (Suberitine) ⬇️

artículo científico publicado en 2012

Downregulation of Fzd6 and Cthrc1 and upregulation of olfactory receptors and protocadherins by dietary beta-carotene in lungs of Bcmo1-/- mice

artículo científico publicado en 2010

Evidence for RPE65-independent vision in the cone-dominated zebrafish retina

artículo científico publicado en 2007

Evidence for compartmentalization of mammalian carotenoid metabolism

artículo científico publicado en 2014

Genetic ablation of the fatty acid-binding protein FABP5 suppresses HER2-induced mammary tumorigenesis

artículo científico publicado en 2013

Genetic dissection in a mouse model reveals interactions between carotenoids and lipid metabolism

artículo científico publicado en 2016

Genetics and diet regulate vitamin A production via the homeobox transcription factor ISX.

artículo científico publicado en 2013

ISX is a retinoic acid-sensitive gatekeeper that controls intestinal beta,beta-carotene absorption and vitamin A production

artículo científico publicado en 2010

Identification of nonvisual photomotor response cells in the vertebrate hindbrain

artículo científico publicado en 2013

In conditions of limited chromophore supply rods entrap 11-cis-retinal leading to loss of cone function and cell death

artículo científico publicado en 2009

Increased adiposity in the retinol saturase-knockout mouse

artículo científico publicado en 2009

Interaction of the retinoic acid signaling pathway with spicule formation in the marine sponge Suberites domuncula through activation of bone morphogenetic protein-1.

artículo científico

Knockout of the Bcmo1 gene results in an inflammatory response in female lung, which is suppressed by dietary beta-carotene

artículo científico publicado en 2010

Lack of β, β-carotene-9', 10'-oxygenase 2 leads to hepatic mitochondrial dysfunction and cellular oxidative stress in mice

artículo científico publicado en 2017

Lecithin:retinol acyltransferase is critical for cellular uptake of vitamin A from serum retinol-binding protein

artículo científico publicado en 2012

Loss of Extracellular Signal-Regulated Kinase 1/2 in the Retinal Pigment Epithelium Leads to RPE65 Decrease and Retinal Degeneration

artículo científico publicado en 2017

Loss of carotene-9',10'-monooxygenase expression increases serum and tissue lycopene concentrations in lycopene-fed mice

artículo científico publicado en 2010

Lycopene and apo-10'-lycopenoic acid have differential mechanisms of protection against hepatic steatosis in β-carotene-9',10'-oxygenase knockout male mice

artículo científico publicado en 2014

Lycopene attenuated hepatic tumorigenesis via differential mechanisms depending on carotenoid cleavage enzyme in mice

artículo científico publicado en 2014

Mammalian carotenoid-oxygenases: key players for carotenoid function and homeostasis

artículo científico publicado en 2011

Metabolic basis of visual cycle inhibition by retinoid and nonretinoid compounds in the vertebrate retina

scientific journal article

Metabolism of carotenoids and retinoids related to vision

artículo científico publicado en 2011

Mutations in the Spliceosome Component CWC27 Cause Retinal Degeneration with or without Additional Developmental Anomalies ⬇️

artículo científico publicado en 2017

NinaB combines carotenoid oxygenase and retinoid isomerase activity in a single polypeptide ⬇️

artículo científico publicado en 2008

NinaB is essential for Drosophila vision but induces retinal degeneration in opsin-deficient photoreceptors

artículo científico publicado en 2009

Nmnat1-Rbp7 Is a Conserved Fusion-Protein That Combines NAD+ Catalysis of Nmnat1 with Subcellular Localization of Rbp7

artículo científico publicado en 2015

Photoreceptor morphology is severely affected in the beta,beta-carotene-15,15'-oxygenase (bcox) zebrafish morphant

artículo científico publicado en 2005

Provitamin A conversion to retinal via the beta,beta-carotene-15,15'-oxygenase (bcox) is essential for pattern formation and differentiation during zebrafish embryogenesis

scientific journal article

Provitamin A metabolism and functions in mammalian biology

artículo científico publicado en 2012

R91W mutation in Rpe65 leads to milder early-onset retinal dystrophy due to the generation of low levels of 11-cis-retinal

artículo científico publicado en 2007

RBP4 disrupts vitamin A uptake homeostasis in a STRA6-deficient animal model for Matthew-Wood syndrome

artículo científico publicado en 2008

RPE65 is essential for the function of cone photoreceptors in NRL-deficient mice

artículo científico publicado en 2007

Requirement for an enzymatic visual cycle in Drosophila

artículo científico publicado en 2009

Retinylamine Benefits Early Diabetic Retinopathy in Mice

artículo científico publicado en 2015

STRA6: role in cellular retinol uptake and efflux

artículo científico publicado en 2015

Sequestration of retinyl esters is essential for retinoid signaling in the zebrafish embryo

artículo científico publicado en 2006

Specificity of zebrafish retinol saturase: formation of all-trans-13,14-dihydroretinol and all-trans-7,8- dihydroretinol

artículo científico publicado en 2007

Structural Insights into the Drosophila melanogaster Retinol Dehydrogenase, a Member of the Short-Chain Dehydrogenase/Reductase Family

artículo científico publicado en 2016

Structural basis of carotenoid cleavage: from bacteria to mammals

artículo científico publicado en 2013

Structure and Spectroscopy of Alkene-Cleaving Dioxygenases Containing an Atypically Coordinated Non-Heme Iron Center

artículo científico publicado en 2017

The Biochemical Basis of Vitamin A3 Production in Arthropod Vision

artículo científico publicado en 2016

The Drosophila class B scavenger receptor NinaD-I is a cell surface receptor mediating carotenoid transport for visual chromophore synthesis.

artículo científico publicado en 2006

The Drosophila visual cycle and de novo chromophore synthesis depends on rdhB.

artículo científico publicado en 2012

The biochemical and structural basis for trans-to-cis isomerization of retinoids in the chemistry of vision

artículo científico publicado en 2010

The retinal G protein-coupled receptor (RGR) enhances isomerohydrolase activity independent of light

artículo científico publicado en 2005

The role of 11-cis-retinyl esters in vertebrate cone vision

artículo científico publicado en 2014

Tomato Powder Inhibits Hepatic Steatosis and Inflammation Potentially Through Restoring SIRT1 Activity and Adiponectin Function Independent of Carotenoid Cleavage Enzymes in Mice.

artículo científico publicado en 2017

Towards a better understanding of carotenoid metabolism in animals

artículo científico publicado en 2004

Transcription factor ISX mediates the cross talk between diet and immunity

artículo científico publicado en 2017

Transport of vitamin A across blood-tissue barriers is facilitated by STRA6.

artículo científico publicado en 2016

Two carotenoid oxygenases contribute to mammalian provitamin A metabolism

artículo científico publicado en 2013

Utilization of Dioxygen by Carotenoid Cleavage Oxygenases

artículo científico publicado en 2015

Vitamin A formation in animals: molecular identification and functional characterization of carotene cleaving enzymes

artículo científico publicado en 2004

beta-Carotene conversion into vitamin A in human retinal pigment epithelial cells

artículo científico publicado en 2005

Lista de obras de

A mitochondrial enzyme degrades carotenoids and protects against oxidative stress

A mutation in the silver gene leads to defects in melanosome biogenesis and alterations in the visual system in the zebrafish mutant fading vision

Activation of retinoic acid receptors by dihydroretinoids

Analysis of Carotenoid Isomerase Activity in a Prototypical Carotenoid Cleavage Enzyme, Apocarotenoid Oxygenase (ACO)

BCDO2 acts as a carotenoid scavenger and gatekeeper for the mitochondrial apoptotic pathway

Beta,beta-carotene decreases peroxisome proliferator receptor gamma activity and reduces lipid storage capacity of adipocytes in a beta,beta-carotene oxygenase 1-dependent manner

Carotenoid oxygenases: cleave it or leave it.

Carotenoids

Characterization of human β,β-carotene-15,15'-monooxygenase (BCMO1) as a soluble monomeric enzyme

Characterization of the Role of β-Carotene 9,10-Dioxygenase in Macular Pigment Metabolism

Colors with functions: elucidating the biochemical and molecular basis of carotenoid metabolism

Conversion of beta-carotene to retinal pigment

Diabetes-induced impairment in visual function in mice: contributions of p38 MAPK, rage, leukocytes, and aldose reductase

Dietary 9-cis-β,β-carotene fails to rescue vision in mouse models of leber congenital amaurosis

Differential expression of the demosponge (Suberites domuncula) carotenoid oxygenases in response to light: protection mechanism against the self-produced toxic protein (Suberitine) ⬇️

Downregulation of Fzd6 and Cthrc1 and upregulation of olfactory receptors and protocadherins by dietary beta-carotene in lungs of Bcmo1-/- mice

Evidence for RPE65-independent vision in the cone-dominated zebrafish retina

Evidence for compartmentalization of mammalian carotenoid metabolism

Genetic ablation of the fatty acid-binding protein FABP5 suppresses HER2-induced mammary tumorigenesis

Genetic dissection in a mouse model reveals interactions between carotenoids and lipid metabolism

Genetics and diet regulate vitamin A production via the homeobox transcription factor ISX.

ISX is a retinoic acid-sensitive gatekeeper that controls intestinal beta,beta-carotene absorption and vitamin A production

Identification of nonvisual photomotor response cells in the vertebrate hindbrain

In conditions of limited chromophore supply rods entrap 11-cis-retinal leading to loss of cone function and cell death

Increased adiposity in the retinol saturase-knockout mouse

Interaction of the retinoic acid signaling pathway with spicule formation in the marine sponge Suberites domuncula through activation of bone morphogenetic protein-1.

Knockout of the Bcmo1 gene results in an inflammatory response in female lung, which is suppressed by dietary beta-carotene

Lack of β, β-carotene-9', 10'-oxygenase 2 leads to hepatic mitochondrial dysfunction and cellular oxidative stress in mice

Lecithin:retinol acyltransferase is critical for cellular uptake of vitamin A from serum retinol-binding protein

Loss of Extracellular Signal-Regulated Kinase 1/2 in the Retinal Pigment Epithelium Leads to RPE65 Decrease and Retinal Degeneration

Loss of carotene-9',10'-monooxygenase expression increases serum and tissue lycopene concentrations in lycopene-fed mice

Lycopene and apo-10'-lycopenoic acid have differential mechanisms of protection against hepatic steatosis in β-carotene-9',10'-oxygenase knockout male mice

Lycopene attenuated hepatic tumorigenesis via differential mechanisms depending on carotenoid cleavage enzyme in mice

Mammalian carotenoid-oxygenases: key players for carotenoid function and homeostasis

Metabolic basis of visual cycle inhibition by retinoid and nonretinoid compounds in the vertebrate retina

Metabolism of carotenoids and retinoids related to vision

Mutations in the Spliceosome Component CWC27 Cause Retinal Degeneration with or without Additional Developmental Anomalies ⬇️

NinaB combines carotenoid oxygenase and retinoid isomerase activity in a single polypeptide ⬇️

NinaB is essential for Drosophila vision but induces retinal degeneration in opsin-deficient photoreceptors

Nmnat1-Rbp7 Is a Conserved Fusion-Protein That Combines NAD+ Catalysis of Nmnat1 with Subcellular Localization of Rbp7

Photoreceptor morphology is severely affected in the beta,beta-carotene-15,15'-oxygenase (bcox) zebrafish morphant

Provitamin A conversion to retinal via the beta,beta-carotene-15,15'-oxygenase (bcox) is essential for pattern formation and differentiation during zebrafish embryogenesis

Provitamin A metabolism and functions in mammalian biology

R91W mutation in Rpe65 leads to milder early-onset retinal dystrophy due to the generation of low levels of 11-cis-retinal

RBP4 disrupts vitamin A uptake homeostasis in a STRA6-deficient animal model for Matthew-Wood syndrome

RPE65 is essential for the function of cone photoreceptors in NRL-deficient mice

Related enzymes solve evolutionarily recurrent problems in the metabolism of carotenoids

Requirement for an enzymatic visual cycle in Drosophila

Retinylamine Benefits Early Diabetic Retinopathy in Mice

STRA6: role in cellular retinol uptake and efflux

Sequestration of retinyl esters is essential for retinoid signaling in the zebrafish embryo

Specificity of zebrafish retinol saturase: formation of all-trans-13,14-dihydroretinol and all-trans-7,8- dihydroretinol

Structural Insights into the Drosophila melanogaster Retinol Dehydrogenase, a Member of the Short-Chain Dehydrogenase/Reductase Family

Structural basis of carotenoid cleavage: from bacteria to mammals

Structure and Spectroscopy of Alkene-Cleaving Dioxygenases Containing an Atypically Coordinated Non-Heme Iron Center

The Biochemical Basis of Vitamin A3 Production in Arthropod Vision

The Drosophila class B scavenger receptor NinaD-I is a cell surface receptor mediating carotenoid transport for visual chromophore synthesis.

The Drosophila visual cycle and de novo chromophore synthesis depends on rdhB.

The biochemical and structural basis for trans-to-cis isomerization of retinoids in the chemistry of vision

The retinal G protein-coupled receptor (RGR) enhances isomerohydrolase activity independent of light

The role of 11-cis-retinyl esters in vertebrate cone vision

Tomato Powder Inhibits Hepatic Steatosis and Inflammation Potentially Through Restoring SIRT1 Activity and Adiponectin Function Independent of Carotenoid Cleavage Enzymes in Mice.

Towards a better understanding of carotenoid metabolism in animals

Transcription factor ISX mediates the cross talk between diet and immunity

Transport of vitamin A across blood-tissue barriers is facilitated by STRA6.

Two carotenoid oxygenases contribute to mammalian provitamin A metabolism

Utilization of Dioxygen by Carotenoid Cleavage Oxygenases

Vitamin A formation in animals: molecular identification and functional characterization of carotene cleaving enzymes

beta-Carotene conversion into vitamin A in human retinal pigment epithelial cells