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A Degenerative/Proinflammatory Intervertebral Disc Organ Culture: An Ex Vivo Model for Anti-inflammatory Drug and Cell Therapy

artículo científico publicado en 2015

A Stro-1(+) human universal stromal feeder layer to expand/maintain human bone marrow hematopoietic stem/progenitor cells in a serum-free culture system.

artículo científico publicado en 2006

A human stromal-based serum-free culture system supports the ex vivo expansion/maintenance of bone marrow and cord blood hematopoietic stem/progenitor cells

artículo científico publicado en 2005

A multicompartment holder for spinner flasks improves expansion and osteogenic differentiation of mesenchymal stem cells in three-dimensional scaffolds

artículo científico publicado en 2014

Adsorbed Fibrinogen stimulates TLR-4 on monocytes and induces BMP-2 expression.

artículo científico publicado en 2016

Adsorbed fibrinogen leads to improved bone regeneration and correlates with differences in the systemic immune response.

artículo científico publicado en 2013

Age-Correlated Phenotypic Alterations in Cells Isolated from Human Degenerated Intervertebral Discs With Contained Hernias.

artículo científico publicado en 2017

An interferon-γ-delivery system based on chitosan/poly(γ-glutamic acid) polyelectrolyte complexes modulates macrophage-derived stimulation of cancer cell invasion in vitro.

artículo científico publicado en 2015

Anti-inflammatory Chitosan/Poly-γ-glutamic acid nanoparticles control inflammation while remodeling extracellular matrix in degenerated intervertebral disc

artículo científico publicado en 2016

Bioactivity of immobilized EGF on self-assembled monolayers: optimization of the immobilization process.

artículo científico publicado en 2010

Biosynthesis of highly pure poly-γ-glutamic acid for biomedical applications

artículo científico publicado en 2012

Chitosan/poly(γ-glutamic acid) nanoparticles incorporating IFN-γ for immune response modulation in the context of colorectal cancer

scientific article published on 24 June 2019

Differences amid bone marrow and cord blood hematopoietic stem/progenitor cell division kinetics

artículo científico publicado en 2009

Dynamic cell-cell interactions between cord blood haematopoietic progenitors and the cellular niche are essential for the expansion of CD34+, CD34+CD38- and early lymphoid CD7+ cells.

artículo científico publicado en 2010

Effect of cell density on mesenchymal stem cells aggregation in RGD-alginate 3D matrices under osteoinductive conditions.

artículo científico publicado en 2014

Extracellular Vesicles: Immunomodulatory messengers in the context of tissue repair/regeneration

artículo científico publicado en 2016

Fibrinogen scaffolds with immunomodulatory properties promote in vivo bone regeneration

artículo científico publicado en 2016

GEORG SCHMORL PRIZE OF THE GERMAN SPINE SOCIETY (DWG) 2018: combined inflammatory and mechanical stress weakens the annulus fibrosus: evidences from a loaded bovine AF organ culture

artículo científico publicado en 2019

Immunomodulation of human mesenchymal stem/stromal cells in intervertebral disc degeneration: insights from a proinflammatory/degenerative ex vivo model

artículo científico publicado en 2017

Improvement of Bovine Nucleus Pulposus Cells Isolation Leads to Identification of Three Phenotypically Distinct Cell Subpopulations.

artículo científico publicado en 2015

Induction of notch signaling by immobilization of jagged-1 on self-assembled monolayers.

artículo científico publicado en 2009

Inflammation in intervertebral disc degeneration and regeneration

artículo científico publicado en 2015

Integrated Analysis of Biological Samples by Imaging Flow Cytometry

artículo científico publicado en 2015

Interferon-Gamma at the Crossroads of Tumor Immune Surveillance or Evasion

artículo científico publicado en 2018

Joint analysis of IVD herniation and degeneration by rat caudal needle puncture model.

artículo científico publicado en 2015

Kinetic analysis of the ex vivo expansion of human hematopoietic stem/progenitor cells.

artículo científico publicado en 2006

Layer-by-layer self-assembly of chitosan and poly(γ-glutamic acid) into polyelectrolyte complexes

scientific article published on 08 November 2011

Macrophage response to chitosan/poly-(γ-glutamic acid) nanoparticles carrying an anti-inflammatory drug

artículo científico publicado en 2015

Macrophages Down-Regulate Gene Expression of Intervertebral Disc Degenerative Markers Under a Pro-inflammatory Microenvironment

artículo científico publicado en 2019

Matrisome Profiling During Intervertebral Disc Development And Ageing

artículo científico publicado en 2017

Mesenchymal Stem/Stromal Cells seeded on cartilaginous endplates promote Intervertebral Disc Regeneration through Extracellular Matrix Remodeling.

artículo científico publicado en 2016

Mesenchymal Stromal Cell Secretome: Influencing Therapeutic Potential by Cellular Pre-conditioning

artículo científico publicado en 2018

Modelling of ex vivo expansion/maintenance of hematopoietic stem cells

artículo científico publicado en 2003

Modulation of the In Vivo Inflammatory Response by Pro- Versus Anti-Inflammatory Intervertebral Disc Treatments

scientific article published on 03 March 2020

Optimization of the use of a pharmaceutical grade xeno-free medium for in vitro expansion of human mesenchymal stem/stromal cells.

artículo científico publicado en 2017

Poly(γ-Glutamic Acid) as an Exogenous Promoter of Chondrogenic Differentiation of Human Mesenchymal Stem/Stromal Cells

artículo científico publicado en 2015

Poly(γ-glutamic acid) and poly(γ-glutamic acid)-based nanocomplexes enhance type II collagen production in intervertebral disc.

artículo científico publicado en 2016

Pro-inflammatory chitosan/poly(γ-glutamic acid) nanoparticles modulate human antigen-presenting cells phenotype and revert their pro-invasive capacity

artículo científico publicado en 2017

Stromal Cell Derived Factor-1-Mediated Migration of Mesenchymal Stem Cells Enhances Collagen Type II Expression in Intervertebral Disc

artículo científico publicado en 2018

The effect of adsorbed fibronectin and osteopontin on macrophage adhesion and morphology on hydrophilic and hydrophobic model surfaces

artículo científico publicado en 2012

The effect of hyaluronan-based delivery of stromal cell-derived factor-1 on the recruitment of MSCs in degenerating intervertebral discs

artículo científico publicado en 2014

The inflammatory response in the regression of lumbar disc herniation

artículo científico publicado en 2018

Xeno-Free Strategies for Safe Human Mesenchymal Stem/Stromal Cell Expansion: Supplements and Coatings

artículo científico publicado en 2017