Lista de obras - Celia Perales - Dominio Público Uruguay

A Multi-Step Process of Viral Adaptation to a Mutagenic Nucleoside Analogue by Modulation of Transition Types Leads to Extinction-Escape

artículo científico publicado en 2010

A Two-Level, Intramutant Spectrum Haplotype Profile of Hepatitis C Virus Revealed by Self-Organized Maps

artículo científico publicado en 2021

A new implication of quasispecies dynamics: Broad virus diversification in absence of external perturbations

artículo científico publicado en 2020

Amino acid substitutions associated with treatment failure of hepatitis C virus infection

artículo científico publicado en 2020

An Efficient Microarray-Based Genotyping Platform for the Identification of Drug-Resistance Mutations in Majority and Minority Subpopulations of HIV-1 Quasispecies

artículo científico publicado en 2016

Antiviral Strategies Based on Lethal Mutagenesis and Error Threshold.

artículo científico

Barrier-Independent, Fitness-Associated Differences in Sofosbuvir Efficacy against Hepatitis C Virus

artículo científico publicado en 2016

Baseline hepatitis C virus resistance-associated substitutions present at frequencies lower than 15% may be clinically significant

artículo científico publicado en 2018

Biological effect of Muller's Ratchet: distant capsid site can affect picornavirus protein processing.

artículo científico publicado en 2009

Broad and Dynamic Diversification of Infectious Hepatitis C Virus in a Cell Culture Environment

artículo científico publicado en 2020

Cleavage of eIF4G by HIV-1 protease: effects on translation.

artículo científico publicado en 2003

Clonality and intracellular polyploidy in virus evolution and pathogenesis

artículo científico publicado en 2015

Contribution of a Multifunctional Polymerase Region of Foot-and-Mouth Disease Virus to Lethal Mutagenesis

artículo científico publicado en 2018

Correction for Quer at al., High-Resolution Hepatitis C Virus Subtyping Using NS5B Deep Sequencing and Phylogeny, an Alternative to Current Methods

artículo científico publicado en 2016

Counteracting Quasispecies Adaptability: Extinction of a Ribavirin-Resistant Virus Mutant by an Alternative Mutagenic Treatment

artículo científico publicado en 2009

Deep sequencing in the management of hepatitis virus infections.

artículo científico publicado en 2016

Deep-sequencing reveals broad subtype-specific HCV resistance mutations associated with treatment failure

artículo científico publicado en 2019

Deletion mutants of VPg reveal new cytopathology determinants in a picornavirus

artículo científico publicado en 2010

Dissimilar Conservation Pattern in Hepatitis C Virus Mutant Spectra, Consensus Sequences, and Data Banks

scientific article published on 27 October 2020

Distance effects during polyprotein processing in the complementation between defective FMDV RNAs

artículo científico publicado en 2016

Enhancement of DNA, cDNA synthesis and fidelity at high temperatures by a dimeric single-stranded DNA-binding protein

artículo científico publicado en 2003

Exploration of sequence space as the basis of viral RNA genome segmentation

artículo científico publicado en 2014

Extinction of hepatitis C virus by ribavirin in hepatoma cells involves lethal mutagenesis

artículo científico publicado en 2013

Extracellular vesicles: Vehicles of en bloc viral transmission

artículo científico publicado en 2019

Favipiravir can evoke lethal mutagenesis and extinction of foot-and-mouth disease virus.

artículo científico publicado en 2017

Hepatitis C Virus RNA-Dependent RNA Polymerase Interacts with the Akt/PKB Kinase and Induces Its Subcellular Relocalization

artículo científico publicado en 2016

Hepatitis C virus early kinetics and resistance-associated substitution dynamics during antiviral therapy with direct-acting antivirals

scholarly article by Elena Perpiñán published in October 2018

Hepatitis C virus-mediated Aurora B kinase inhibition modulates inflammatory pathway and viral infectivity

artículo científico publicado en 2015

High HCV subtype heterogeneity in a chronically infected general population revealed by high-resolution hepatitis C virus subtyping

artículo científico publicado en 2017

High-resolution hepatitis C virus subtyping using NS5B deep sequencing and phylogeny, an alternative to current methods

artículo científico publicado en 2015

Identification of host and viral factors involved in a dissimilar resolution of a hepatitis C virus infection

artículo científico publicado en 2013

Increased replicative fitness can lead to decreased drug sensitivity of hepatitis C virus

artículo científico publicado en 2014

Influence of mutagenesis and viral load on the sustained low-level replication of an RNA virus

artículo científico publicado en 2011

Insights into RNA virus mutant spectrum and lethal mutagenesis events: replicative interference and complementation by multiple point mutants

artículo científico publicado en 2007

Internal Disequilibria and Phenotypic Diversification during Replication of Hepatitis C Virus in a Noncoevolving Cellular Environment

artículo científico publicado en 2017

Lethal Mutagenesis of Hepatitis C Virus Induced by Favipiravir.

artículo científico publicado en 2016

Lethal mutagenesis of foot-and-mouth disease virus involves shifts in sequence space

artículo científico publicado en 2011

Lethal mutagenesis of viruses ⬇️

artículo científico publicado el 4 de octubre de 2011

MOLECULAR AND EVOLUTIONARY MECHANISMS OF VIRAL EMERGENCE

Microarray-based identification of antigenic variants of foot-and-mouth disease virus: a bioinformatics quality assessment

artículo científico publicado en 2006

Molecular and Functional Bases of Selection against a Mutation Bias in an RNA Virus.

artículo científico publicado en 2017

Molecular basis of interferon resistance in hepatitis C virus

artículo científico

Molecular characterization of a dual inhibitory and mutagenic activity of 5-fluorouridine triphosphate on viral RNA synthesis. Implications for lethal mutagenesis.

artículo científico publicado en 2008

Monitoring sequence space as a test for the target of selection in viruses.

artículo científico publicado en 2005

Multifunctionality of a picornavirus polymerase domain: nuclear localization signal and nucleotide recognition

artículo científico publicado en 2015

Mutant spectra in virus behavior

Mutation, Quasispecies, and Lethal Mutagenesis

New hepatitis C virus genotype 1 subtype naturally harbouring resistance-associated mutations to NS5A inhibitors

artículo científico publicado en 2017

New real-time-PCR method to identify single point mutations in hepatitis C virus.

artículo científico publicado en 2016

Persistence of foot-and-mouth disease virus in cell culture revisited: implications for contingency in evolution.

artículo científico publicado en 2008

Pipeline for specific subtype amplification and drug resistance detection in hepatitis C virus

artículo científico publicado en 2018

Potential benefits of sequential inhibitor-mutagen treatments of RNA virus infections

artículo científico publicado en 2009

Quasispecies and Drug Resistance

Quasispecies and virus.

artículo científico publicado en 2018

Quasispecies as a matter of fact: viruses and beyond.

artículo científico publicado en 2011

Quasispecies dynamics and clinical significance of HCV antiviral resistance

article

Rare haplotype load as marker for lethal mutagenesis

artículo científico publicado en 2018

Regulation of HIV-1 env mRNA translation by Rev protein

scientific article published on 01 March 2005

Resistance of Hepatitis C Virus to Inhibitors: Complexity and Clinical Implications

artículo científico publicado en 2015

Resistance of high fitness hepatitis C virus to lethal mutagenesis

scholarly article by Isabel Gallego published in October 2018

Response of hepatitis C virus to long-term passage in the presence of alpha interferon: multiple mutations and a common phenotype.

artículo científico publicado en 2013

SARS-CoV-2 Point Mutation and Deletion Spectra and Their Association with Different Disease Outcomes

artículo científico publicado en 2022

Synergistic lethal mutagenesis of hepatitis C virus

artículo científico publicado en 2019

Tempo and mode of inhibitor-mutagen antiviral therapies: a multidisciplinary approach

artículo científico publicado en 2011

The archaeology of coding RNA

scientific article published on 25 June 2019

The impact of quasispecies dynamics on the use of therapeutics ⬇️

artículo científico publicado el 16 de septiembre de 2012

The increasing impact of lethal mutagenesis of viruses

scientific article published on 01 July 2019

Ultra-deep pyrosequencing (UDPS) data treatment to study amplicon HCV minor variants.

artículo científico publicado en 2013

Viral Quasispecies and Lethal Mutagenesis

article published in 2016

Viral Quasispecies: Dynamics, Interactions, and Pathogenesis**Dedicated to Manfred Eigen on the occasion of his 80th birthday, for the insights that his pioneer studies have represented for virology

article

Viral fitness can influence the repertoire of virus variants selected by antibodies.

artículo científico publicado en 2006

Viral fitness: history and relevance for viral pathogenesis and antiviral interventions

scientific article published on 01 March 2019

Viral genome segmentation can result from a trade-off between genetic content and particle stability

artículo científico publicado en 2011

Viral quasispecies

scientific article published on 17 October 2019

Viral quasispecies complexity measures.

artículo científico publicado en 2016

Viral quasispecies evolution

artículo científico publicado en 2012

Lista de obras de Celia Perales

A Multi-Step Process of Viral Adaptation to a Mutagenic Nucleoside Analogue by Modulation of Transition Types Leads to Extinction-Escape

A Two-Level, Intramutant Spectrum Haplotype Profile of Hepatitis C Virus Revealed by Self-Organized Maps

A new implication of quasispecies dynamics: Broad virus diversification in absence of external perturbations

Amino acid substitutions associated with treatment failure of hepatitis C virus infection

An Efficient Microarray-Based Genotyping Platform for the Identification of Drug-Resistance Mutations in Majority and Minority Subpopulations of HIV-1 Quasispecies

Antiviral Strategies Based on Lethal Mutagenesis and Error Threshold.

Barrier-Independent, Fitness-Associated Differences in Sofosbuvir Efficacy against Hepatitis C Virus

Baseline hepatitis C virus resistance-associated substitutions present at frequencies lower than 15% may be clinically significant

Biological effect of Muller's Ratchet: distant capsid site can affect picornavirus protein processing.

Broad and Dynamic Diversification of Infectious Hepatitis C Virus in a Cell Culture Environment

Cleavage of eIF4G by HIV-1 protease: effects on translation.

Clonality and intracellular polyploidy in virus evolution and pathogenesis

Contribution of a Multifunctional Polymerase Region of Foot-and-Mouth Disease Virus to Lethal Mutagenesis

Correction for Quer at al., High-Resolution Hepatitis C Virus Subtyping Using NS5B Deep Sequencing and Phylogeny, an Alternative to Current Methods

Counteracting Quasispecies Adaptability: Extinction of a Ribavirin-Resistant Virus Mutant by an Alternative Mutagenic Treatment

Deep sequencing in the management of hepatitis virus infections.

Deep-sequencing reveals broad subtype-specific HCV resistance mutations associated with treatment failure

Deletion mutants of VPg reveal new cytopathology determinants in a picornavirus

Dissimilar Conservation Pattern in Hepatitis C Virus Mutant Spectra, Consensus Sequences, and Data Banks

Distance effects during polyprotein processing in the complementation between defective FMDV RNAs

Enhancement of DNA, cDNA synthesis and fidelity at high temperatures by a dimeric single-stranded DNA-binding protein

Exploration of sequence space as the basis of viral RNA genome segmentation

Extinction of hepatitis C virus by ribavirin in hepatoma cells involves lethal mutagenesis

Extracellular vesicles: Vehicles of en bloc viral transmission

Favipiravir can evoke lethal mutagenesis and extinction of foot-and-mouth disease virus.

Hepatitis C Virus RNA-Dependent RNA Polymerase Interacts with the Akt/PKB Kinase and Induces Its Subcellular Relocalization

Hepatitis C virus early kinetics and resistance-associated substitution dynamics during antiviral therapy with direct-acting antivirals

Hepatitis C virus-mediated Aurora B kinase inhibition modulates inflammatory pathway and viral infectivity

High HCV subtype heterogeneity in a chronically infected general population revealed by high-resolution hepatitis C virus subtyping

High-resolution hepatitis C virus subtyping using NS5B deep sequencing and phylogeny, an alternative to current methods

Identification of host and viral factors involved in a dissimilar resolution of a hepatitis C virus infection

Increased replicative fitness can lead to decreased drug sensitivity of hepatitis C virus

Influence of mutagenesis and viral load on the sustained low-level replication of an RNA virus

Insights into RNA virus mutant spectrum and lethal mutagenesis events: replicative interference and complementation by multiple point mutants

Internal Disequilibria and Phenotypic Diversification during Replication of Hepatitis C Virus in a Noncoevolving Cellular Environment

Lethal Mutagenesis of Hepatitis C Virus Induced by Favipiravir.

Lethal mutagenesis of foot-and-mouth disease virus involves shifts in sequence space

Lethal mutagenesis of viruses ⬇️

MOLECULAR AND EVOLUTIONARY MECHANISMS OF VIRAL EMERGENCE

Microarray-based identification of antigenic variants of foot-and-mouth disease virus: a bioinformatics quality assessment

Molecular and Functional Bases of Selection against a Mutation Bias in an RNA Virus.

Molecular basis of interferon resistance in hepatitis C virus

Molecular characterization of a dual inhibitory and mutagenic activity of 5-fluorouridine triphosphate on viral RNA synthesis. Implications for lethal mutagenesis.

Monitoring sequence space as a test for the target of selection in viruses.

Multifunctionality of a picornavirus polymerase domain: nuclear localization signal and nucleotide recognition

Mutant spectra in virus behavior

Mutation, Quasispecies, and Lethal Mutagenesis

New hepatitis C virus genotype 1 subtype naturally harbouring resistance-associated mutations to NS5A inhibitors

New real-time-PCR method to identify single point mutations in hepatitis C virus.

Persistence of foot-and-mouth disease virus in cell culture revisited: implications for contingency in evolution.

Pipeline for specific subtype amplification and drug resistance detection in hepatitis C virus

Potential benefits of sequential inhibitor-mutagen treatments of RNA virus infections

Quasispecies and Drug Resistance

Quasispecies and Drug Resistance

Quasispecies and virus.

Quasispecies as a matter of fact: viruses and beyond.

Quasispecies dynamics and clinical significance of HCV antiviral resistance

Rare haplotype load as marker for lethal mutagenesis

Regulation of HIV-1 env mRNA translation by Rev protein

Resistance of Hepatitis C Virus to Inhibitors: Complexity and Clinical Implications

Resistance of high fitness hepatitis C virus to lethal mutagenesis

Response of hepatitis C virus to long-term passage in the presence of alpha interferon: multiple mutations and a common phenotype.

SARS-CoV-2 Point Mutation and Deletion Spectra and Their Association with Different Disease Outcomes

Synergistic lethal mutagenesis of hepatitis C virus

Tempo and mode of inhibitor-mutagen antiviral therapies: a multidisciplinary approach

The archaeology of coding RNA

The impact of quasispecies dynamics on the use of therapeutics ⬇️

The increasing impact of lethal mutagenesis of viruses

Ultra-deep pyrosequencing (UDPS) data treatment to study amplicon HCV minor variants.

Viral Quasispecies and Lethal Mutagenesis

Viral Quasispecies: Dynamics, Interactions, and Pathogenesis**Dedicated to Manfred Eigen on the occasion of his 80th birthday, for the insights that his pioneer studies have represented for virology

Viral fitness can influence the repertoire of virus variants selected by antibodies.

Viral fitness: history and relevance for viral pathogenesis and antiviral interventions

Viral genome segmentation can result from a trade-off between genetic content and particle stability

Viral quasispecies

Viral quasispecies complexity measures.

Viral quasispecies evolution