Lista de obras -

A PTEN inhibitor displays preclinical activity against hepatocarcinoma cells

artículo científico publicado en 2016

A new extracellular matrix protein of the sea urchin embryo with properties of a substrate adhesion molecule

artículo científico publicado en 1992

Abilities of β-Estradiol to interact with chemotherapeutic drugs, signal transduction inhibitors and nutraceuticals and alter the proliferation of pancreatic cancer cells

scientific article published on 18 October 2019

Advances in targeting signal transduction pathways

artículo científico publicado en 2012

Antitumor effects of curcumin, alone or in combination with cisplatin or doxorubicin, on human hepatic cancer cells. Analysis of their possible relationship to changes in NF-kB activation levels and in IAP gene expression

artículo científico publicado en 2005

Antitumor effects of dehydroxymethylepoxyquinomicin, a novel nuclear factor-kappaB inhibitor, in human liver cancer cells are mediated through a reactive oxygen species-dependent mechanism

artículo científico publicado en 2009

Antitumor effects of the novel NF-kappaB inhibitor dehydroxymethyl-epoxyquinomicin on human hepatic cancer cells: analysis of synergy with cisplatin and of possible correlation with inhibition of pro-survival genes and IL-6 production.

artículo científico publicado en 2006

Aromatase and amphiregulin are correspondingly expressed in human liver cancer cells

artículo científico publicado en 2009

Association Between MICA Gene Variants and the Risk of Hepatitis C Virus-Induced Hepatocellular Cancer in a Sicilian Population Sample.

artículo científico publicado en 2018

Biocompatible Lipid Nanoparticles as Carriers To Improve Curcumin Efficacy in Ovarian Cancer Treatment.

artículo científico publicado en 2017

COX-2-dependent and COX-2-independent mode of action of celecoxib in human liver cancer cells.

artículo científico publicado en 2011

Calcium-dependent self-aggregation of toposome, a sea urchin embryo cell adhesion molecule

artículo científico publicado en 1992

Cancer therapy and treatments during COVID-19 era

scientific article published on 26 June 2020

Cationic Solid Lipid Nanoparticles as Non Viral Vectors for the Inhibition of Hepatocellular Carcinoma Growth by RNA Interference

artículo científico publicado en 2018

Circulating intercellular adhesion molecule-1 in chronic hepatitis C patients with normal or elevated aminotransferase before and after alpha-interferon treatment

artículo científico publicado en 2003

Cloning and expression of a type IX-like collagen in tissues of the ascidian Ciona intestinalis.

artículo científico publicado en 2002

Correction to: Entrapment of an EGFR inhibitor into nanostructured lipid carriers (NLC) improves its antitumor activity against human hepatocarcinoma cells

artículo científico publicado en 2018

Correlation between expression of cyclooxygenase-2 and the presence of inflammatory cells in human primary hepatocellular carcinoma: possible role in tumor promotion and angiogenesis

artículo científico publicado en 2005

Critical Roles of EGFR Family Members in Breast Cancer and Breast Cancer Stem Cells: Targets for Therapy

artículo científico publicado en 2016

Cyclooxygenase-2 expression in chronic liver diseases and hepatocellular carcinoma: an immunohistochemical study .

artículo científico publicado en 2009

Cyclooxygenases in hepatocellular carcinoma.

artículo científico publicado en 2006

Cytotoxic activity of the novel small molecule AKT inhibitor SC66 in hepatocellular carcinoma cells

artículo científico publicado en 2015

Deregulation of the EGFR/PI3K/PTEN/Akt/mTORC1 pathway in breast cancer: possibilities for therapeutic intervention

artículo científico publicado en 2014

Diverse roles of GSK-3: tumor promoter-tumor suppressor, target in cancer therapy

artículo científico

Ectopic NGAL expression can alter sensitivity of breast cancer cells to EGFR, Bcl-2, CaM-K inhibitors and the plant natural product berberine

artículo científico publicado en 2012

Effects of ectopic expression of NGAL on doxorubicin sensitivity

artículo científico publicado en 2012

Effects of mutations in Wnt/β-catenin, hedgehog, Notch and PI3K pathways on GSK-3 activity-Diverse effects on cell growth, metabolism and cancer

artículo científico

Emerging MEK inhibitors.

artículo científico publicado en 2010

Emerging Raf inhibitors.

artículo científico publicado en 2009

Entrapment of an EGFR inhibitor into nanostructured lipid carriers (NLC) improves its antitumor activity against human hepatocarcinoma cells

artículo científico publicado en 2014

Epidemiology, risk factors, and natural history of hepatocellular carcinoma.

artículo científico publicado en 2002

Expression of IAPs and alternative splice variants in hepatocellular carcinoma tissues and cells

artículo científico publicado en 2004

Expression of WISPs and of their novel alternative variants in human hepatocellular carcinoma cells.

artículo científico publicado en 2004

Expression of the IAPs in multidrug resistant tumor cells

artículo científico publicado en 2004

Frequent Alteration of the Yin Yang 1/Raf-1 Kinase Inhibitory Protein Ratio in Hepatocellular Carcinoma

artículo científico publicado en 2011

GSK-3 as potential target for therapeutic intervention in cancer

artículo científico publicado en 2014

GSK-3 in liver diseases: Friend or foe?

artículo científico publicado en 2020

GSK-3beta is a critical mediator of tetrandrine induced cell cycle arrest and cytotoxicity

artículo científico publicado en 2008

Heat shock protein 70 serum levels differ significantly in patients with chronic hepatitis, liver cirrhosis, and hepatocellular carcinoma

artículo científico publicado en 2014

Hepatic and circulating levels of PCSK9 in morbidly obese patients: relation with severity of liver steatosis

scientific article published on 07 August 2020

Histamine and spontaneously released mast cell granules affect the cell growth of human hepatocellular carcinoma cells

artículo científico publicado en 2007

IL-6 -174G/C polymorphism and IL-6 serum levels in patients with liver cirrhosis and hepatocellular carcinoma.

artículo científico publicado en 2011

Identification of Type I and IX Collagens in the Ascidian Ciona intestinalis

Identification of an LPS-Induced Chemo-Attractive Peptide from Ciona robusta

scientific article published on 12 April 2020

Induction of apoptosis and inhibition of cell growth in human hepatocellular carcinoma cells by COX-2 inhibitors.

artículo científico publicado en 2004

Induction of apoptosis by the adenosine derivative IB-MECA in parental or multidrug-resistant HL-60 leukemia cells: possible relationship to the effects on inhibitor of apoptosis protein levels

artículo científico publicado en 2005

Induction of apoptosis by the proteasome inhibitor MG132 in human HCC cells: Possible correlation with specific caspase-dependent cleavage of beta-catenin and inhibition of beta-catenin-mediated transactivation.

artículo científico publicado en 2004

Interleukin-6 and its soluble receptor in patients with liver cirrhosis and hepatocellular carcinoma

artículo científico publicado en 2006

Lipid nanocarriers containing sorafenib inhibit colonies formation in human hepatocarcinoma cells

artículo científico publicado en 2015

Management of Liver Failure: From Transplantation to Cell-Based Therapy

artículo científico publicado en 2011

Molecular mechanisms of sorafenib action in liver cancer cells.

artículo científico publicado en 2012

Mutations and deregulation of Ras/Raf/MEK/ERK and PI3K/PTEN/Akt/mTOR cascades which alter therapy response

artículo científico publicado en 2012

NAIP-deltaEx10-11: a novel splice variant of the apoptosis inhibitor NAIP differently expressed in drug-sensitive and multidrug-resistant HL60 leukemia cells

artículo científico publicado en 2002

Nanoassemblies Based on Supramolecular Complexes of Nonionic Amphiphilic Cyclodextrin and Sorafenib as Effective Weapons to Kill Human HCC Cells

artículo científico publicado en 2015

Nanoparticles of a polyaspartamide-based brush copolymer for modified release of sorafenib: In vitro and in vivo evaluation

artículo científico publicado en 2017

Nanostructured lipid carriers-containing anticancer compounds: preparation, characterization, and cytotoxicity studies

artículo científico publicado en 2007

New landscapes and horizons in hepatocellular carcinoma therapy

scientific article published on 04 February 2020

Novel cationic solid-lipid nanoparticles as non-viral vectors for gene delivery

artículo científico publicado en 2007

Novel combination of celecoxib and proteasome inhibitor MG132 provides synergistic antiproliferative and proapoptotic effects in human liver tumor cells

artículo científico publicado en 2010

Novel combination of sorafenib and celecoxib provides synergistic anti-proliferative and pro-apoptotic effects in human liver cancer cells.

artículo científico publicado en 2013

Oleocanthal exerts antitumor effects on human liver and colon cancer cells through ROS generation

artículo científico publicado en 2017

Pivotal roles of glycogen synthase-3 in hepatocellular carcinoma

artículo científico publicado en 2017

Poly (ADP-ribose) polymerase inhibition synergizes with the NF-κB inhibitor DHMEQ to kill hepatocellular carcinoma cells.

artículo científico publicado en 2014

Potentiation of the antitumor effects of both selective cyclooxygenase-1 and cyclooxygenase-2 inhibitors in human hepatic cancer cells by inhibition of the MEK/ERK pathway.

artículo científico publicado en 2007

Preclinical evaluation of antitumor activity of the proteasome inhibitor MLN2238 (ixazomib) in hepatocellular carcinoma cells

artículo científico publicado en 2018

Properties of sea urchin coelomocyte agglutinins

artículo científico publicado en 1996

Prostaglandin E2 receptors and COX enzymes in human hepatocellular carcinoma: role in the regulation of cell growth.

artículo científico publicado en 2009

RAS/RAF/MEK/ERK, PI3K/PTEN/AKT/mTORC1 and TP53 pathways and regulatory miRs as therapeutic targets in hepatocellular carcinoma

scientific article published on 04 November 2019

Ras/Raf/MEK/ERK and PI3K/PTEN/Akt/mTOR cascade inhibitors: how mutations can result in therapy resistance and how to overcome resistance

artículo científico publicado en 2012

Ras/Raf/MEK/ERK and PI3K/PTEN/Akt/mTOR inhibitors: rationale and importance to inhibiting these pathways in human health

artículo científico publicado en 2011

Regulation of GSK-3 activity by curcumin, berberine and resveratrol: Potential effects on multiple diseases

artículo científico publicado en 2017

Resistance to diverse apoptotic triggers in multidrug resistant HL60 cells and its possible relationship to the expression of P-glycoprotein, Fas and of the novel anti-apoptosis factors IAP (inhibitory of apoptosis proteins).

artículo científico publicado en 2002

Response to antiviral therapy and hepatic expression of cyclooxygenases in chronic hepatitis C.

artículo científico publicado en 2007

Roles of EGFR and KRAS and their downstream signaling pathways in pancreatic cancer and pancreatic cancer stem cells

artículo científico

Roles of GSK-3 and microRNAs on epithelial mesenchymal transition and cancer stem cells

artículo científico publicado en 2016

Roles of NGAL and MMP-9 in the tumor microenvironment and sensitivity to targeted therapy

artículo científico

Roles of TP53 in determining therapeutic sensitivity, growth, cellular senescence, invasion and metastasis

artículo científico publicado en 2016

Roles of p53, NF-κB and the androgen receptor in controlling NGAL expression in prostate cancer cell lines

article

Roles of signaling pathways in drug resistance, cancer initiating cells and cancer progression and metastasis

artículo científico publicado en 2014

Roles of the Raf/MEK/ERK and PI3K/PTEN/Akt/mTOR pathways in controlling growth and sensitivity to therapy-implications for cancer and aging

artículo científico publicado en 2011

Significance of Autologous Interleukin-6 Production in the HA22T/VGH Cell Model of Hepatocellular Carcinoma

artículo científico publicado en 2006

Synthesis and characterization of polyaminoacidic polycations for gene delivery

artículo científico publicado en 2005

Synthetic peptide-labelled micelles for active targeting of cells overexpressing EGF receptors

artículo científico publicado en 2019

Targeted therapy for hepatocellular carcinoma: novel agents on the horizon

artículo científico publicado en 2012

Targeting GSK3 and Associated Signaling Pathways Involved in Cancer

scientific article published on 30 April 2020

Targeting HSP90 with the small molecule inhibitor AUY922 (luminespib) as a treatment strategy against hepatocellular carcinoma

scientific article published on 24 December 2018

Targeting breast cancer initiating cells: advances in breast cancer research and therapy

artículo científico publicado en 2014

Targeting the Raf/MEK/ERK pathway with small-molecule inhibitors.

artículo científico publicado en 2008

Targeting the cancer initiating cell: the ultimate target for cancer therapy.

artículo científico publicado en 2012

The Prevalence of NAFLD and Fibrosis in Bariatric Surgery Patients and the Reliability of Noninvasive Diagnostic Methods

scientific article published on 26 April 2020

The Role of GSK-3 in Cancer Immunotherapy: GSK-3 Inhibitors as a New Frontier in Cancer Treatment

artículo científico publicado en 2020

The novel NF-κB inhibitor DHMEQ synergizes with celecoxib to exert antitumor effects on human liver cancer cells by a ROS-dependent mechanism.

artículo científico publicado en 2012

The selective cyclooxygenase-1 inhibitor SC-560 suppresses cell proliferation and induces apoptosis in human hepatocellular carcinoma cells

artículo científico publicado en 2006

Therapeutic resistance resulting from mutations in Raf/MEK/ERK and PI3K/PTEN/Akt/mTOR signaling pathways.

artículo científico publicado en 2011

Transcriptional regulation of miR-224 upregulated in human HCCs by NFκB inflammatory pathways

artículo científico publicado en 2011

Lista de obras de

A PTEN inhibitor displays preclinical activity against hepatocarcinoma cells

A new extracellular matrix protein of the sea urchin embryo with properties of a substrate adhesion molecule

Abilities of β-Estradiol to interact with chemotherapeutic drugs, signal transduction inhibitors and nutraceuticals and alter the proliferation of pancreatic cancer cells

Advances in targeting signal transduction pathways

Antitumor effects of curcumin, alone or in combination with cisplatin or doxorubicin, on human hepatic cancer cells. Analysis of their possible relationship to changes in NF-kB activation levels and in IAP gene expression

Antitumor effects of dehydroxymethylepoxyquinomicin, a novel nuclear factor-kappaB inhibitor, in human liver cancer cells are mediated through a reactive oxygen species-dependent mechanism

Antitumor effects of the novel NF-kappaB inhibitor dehydroxymethyl-epoxyquinomicin on human hepatic cancer cells: analysis of synergy with cisplatin and of possible correlation with inhibition of pro-survival genes and IL-6 production.

Aromatase and amphiregulin are correspondingly expressed in human liver cancer cells

Association Between MICA Gene Variants and the Risk of Hepatitis C Virus-Induced Hepatocellular Cancer in a Sicilian Population Sample.

Biocompatible Lipid Nanoparticles as Carriers To Improve Curcumin Efficacy in Ovarian Cancer Treatment.

COX-2-dependent and COX-2-independent mode of action of celecoxib in human liver cancer cells.

Calcium-dependent self-aggregation of toposome, a sea urchin embryo cell adhesion molecule

Cancer therapy and treatments during COVID-19 era

Cationic Solid Lipid Nanoparticles as Non Viral Vectors for the Inhibition of Hepatocellular Carcinoma Growth by RNA Interference

Circulating intercellular adhesion molecule-1 in chronic hepatitis C patients with normal or elevated aminotransferase before and after alpha-interferon treatment

Cloning and expression of a type IX-like collagen in tissues of the ascidian Ciona intestinalis.

Correction to: Entrapment of an EGFR inhibitor into nanostructured lipid carriers (NLC) improves its antitumor activity against human hepatocarcinoma cells

Correlation between expression of cyclooxygenase-2 and the presence of inflammatory cells in human primary hepatocellular carcinoma: possible role in tumor promotion and angiogenesis

Critical Roles of EGFR Family Members in Breast Cancer and Breast Cancer Stem Cells: Targets for Therapy

Cyclooxygenase-2 expression in chronic liver diseases and hepatocellular carcinoma: an immunohistochemical study .

Cyclooxygenases in hepatocellular carcinoma.

Cytotoxic activity of the novel small molecule AKT inhibitor SC66 in hepatocellular carcinoma cells

Deregulation of the EGFR/PI3K/PTEN/Akt/mTORC1 pathway in breast cancer: possibilities for therapeutic intervention

Diverse roles of GSK-3: tumor promoter-tumor suppressor, target in cancer therapy

Ectopic NGAL expression can alter sensitivity of breast cancer cells to EGFR, Bcl-2, CaM-K inhibitors and the plant natural product berberine

Effects of ectopic expression of NGAL on doxorubicin sensitivity

Effects of mutations in Wnt/β-catenin, hedgehog, Notch and PI3K pathways on GSK-3 activity-Diverse effects on cell growth, metabolism and cancer

Emerging MEK inhibitors.

Emerging Raf inhibitors.

Entrapment of an EGFR inhibitor into nanostructured lipid carriers (NLC) improves its antitumor activity against human hepatocarcinoma cells

Epidemiology, risk factors, and natural history of hepatocellular carcinoma.

Expression of IAPs and alternative splice variants in hepatocellular carcinoma tissues and cells

Expression of WISPs and of their novel alternative variants in human hepatocellular carcinoma cells.

Expression of the IAPs in multidrug resistant tumor cells

Frequent Alteration of the Yin Yang 1/Raf-1 Kinase Inhibitory Protein Ratio in Hepatocellular Carcinoma

GSK-3 as potential target for therapeutic intervention in cancer

GSK-3 in liver diseases: Friend or foe?

GSK-3beta is a critical mediator of tetrandrine induced cell cycle arrest and cytotoxicity

Heat shock protein 70 serum levels differ significantly in patients with chronic hepatitis, liver cirrhosis, and hepatocellular carcinoma

Hepatic and circulating levels of PCSK9 in morbidly obese patients: relation with severity of liver steatosis

Histamine and spontaneously released mast cell granules affect the cell growth of human hepatocellular carcinoma cells

IL-6 -174G/C polymorphism and IL-6 serum levels in patients with liver cirrhosis and hepatocellular carcinoma.

Identification of Type I and IX Collagens in the Ascidian Ciona intestinalis

Identification of an LPS-Induced Chemo-Attractive Peptide from Ciona robusta

Induction of apoptosis and inhibition of cell growth in human hepatocellular carcinoma cells by COX-2 inhibitors.

Induction of apoptosis by the adenosine derivative IB-MECA in parental or multidrug-resistant HL-60 leukemia cells: possible relationship to the effects on inhibitor of apoptosis protein levels

Induction of apoptosis by the proteasome inhibitor MG132 in human HCC cells: Possible correlation with specific caspase-dependent cleavage of beta-catenin and inhibition of beta-catenin-mediated transactivation.

Interleukin-6 and its soluble receptor in patients with liver cirrhosis and hepatocellular carcinoma

Lipid nanocarriers containing sorafenib inhibit colonies formation in human hepatocarcinoma cells

Management of Liver Failure: From Transplantation to Cell-Based Therapy

Molecular mechanisms of sorafenib action in liver cancer cells.

Mutations and deregulation of Ras/Raf/MEK/ERK and PI3K/PTEN/Akt/mTOR cascades which alter therapy response

NAIP-deltaEx10-11: a novel splice variant of the apoptosis inhibitor NAIP differently expressed in drug-sensitive and multidrug-resistant HL60 leukemia cells

Nanoassemblies Based on Supramolecular Complexes of Nonionic Amphiphilic Cyclodextrin and Sorafenib as Effective Weapons to Kill Human HCC Cells

Nanoparticles of a polyaspartamide-based brush copolymer for modified release of sorafenib: In vitro and in vivo evaluation

Nanostructured lipid carriers-containing anticancer compounds: preparation, characterization, and cytotoxicity studies

New landscapes and horizons in hepatocellular carcinoma therapy

Novel cationic solid-lipid nanoparticles as non-viral vectors for gene delivery

Novel combination of celecoxib and proteasome inhibitor MG132 provides synergistic antiproliferative and proapoptotic effects in human liver tumor cells

Novel combination of sorafenib and celecoxib provides synergistic anti-proliferative and pro-apoptotic effects in human liver cancer cells.

Oleocanthal exerts antitumor effects on human liver and colon cancer cells through ROS generation

Pivotal roles of glycogen synthase-3 in hepatocellular carcinoma

Poly (ADP-ribose) polymerase inhibition synergizes with the NF-κB inhibitor DHMEQ to kill hepatocellular carcinoma cells.

Potentiation of the antitumor effects of both selective cyclooxygenase-1 and cyclooxygenase-2 inhibitors in human hepatic cancer cells by inhibition of the MEK/ERK pathway.

Preclinical evaluation of antitumor activity of the proteasome inhibitor MLN2238 (ixazomib) in hepatocellular carcinoma cells

Properties of sea urchin coelomocyte agglutinins

Prostaglandin E2 receptors and COX enzymes in human hepatocellular carcinoma: role in the regulation of cell growth.

RAS/RAF/MEK/ERK, PI3K/PTEN/AKT/mTORC1 and TP53 pathways and regulatory miRs as therapeutic targets in hepatocellular carcinoma

Ras/Raf/MEK/ERK and PI3K/PTEN/Akt/mTOR cascade inhibitors: how mutations can result in therapy resistance and how to overcome resistance

Ras/Raf/MEK/ERK and PI3K/PTEN/Akt/mTOR inhibitors: rationale and importance to inhibiting these pathways in human health

Regulation of GSK-3 activity by curcumin, berberine and resveratrol: Potential effects on multiple diseases

Resistance to diverse apoptotic triggers in multidrug resistant HL60 cells and its possible relationship to the expression of P-glycoprotein, Fas and of the novel anti-apoptosis factors IAP (inhibitory of apoptosis proteins).

Response to antiviral therapy and hepatic expression of cyclooxygenases in chronic hepatitis C.

Roles of EGFR and KRAS and their downstream signaling pathways in pancreatic cancer and pancreatic cancer stem cells

Roles of GSK-3 and microRNAs on epithelial mesenchymal transition and cancer stem cells

Roles of NGAL and MMP-9 in the tumor microenvironment and sensitivity to targeted therapy

Roles of TP53 in determining therapeutic sensitivity, growth, cellular senescence, invasion and metastasis

Roles of p53, NF-κB and the androgen receptor in controlling NGAL expression in prostate cancer cell lines

Roles of signaling pathways in drug resistance, cancer initiating cells and cancer progression and metastasis