Lista de obras -

192. Action of Venom Metalloproteinases on Basement Membranes: Pathogenesis of Hemorrhage and Blistering in Snakebite Envenomings

artículo científico publicado en 2012

A Comprehensive View of the Structural and Functional Alterations of Extracellular Matrix by Snake Venom Metalloproteinases (SVMPs): Novel Perspectives on the Pathophysiology of Envenoming

artículo científico publicado en 2016

A representative metalloprotease induces PGE2 synthesis in fibroblast-like synoviocytes via the NF-κB/COX-2 pathway with amplification by IL-1β and the EP4 receptor

artículo científico publicado en 2020

Amino acid sequence and crystal structure of BaP1, a metalloproteinase from Bothrops asper snake venom that exerts multiple tissue-damaging activities

artículo científico publicado en 2003

Analysis of wound exudates reveals differences in the patterns of tissue damage and inflammation induced by the venoms of Daboia russelii and Bothrops asper in mice

artículo científico publicado en 2020

Anti-human erythrocyte antibodies in horse-derived antivenoms used in the treatment of snakebite envenomations

artículo científico publicado en 2006

Assessment of metalloproteinase inhibitors clodronate and doxycycline in the neutralization of hemorrhage and coagulopathy induced by Bothrops asper snake venom

artículo científico publicado en 2008

Basement membrane degradation and inflammation play a role in the pulmonary hemorrhage induced by a P-III snake venom metalloproteinase

artículo científico publicado en 2021

Biochemical and biological characterization of two serine proteinases from Colombian Crotalus durissus cumanensis snake venom

artículo científico publicado en 2012

Biomolecular investigation into systemic vascular leakage and kidney dysfunction induced by Russell's viper: A unique type of vascular toxicity and pathophysiology in viperid envenomings

artículo científico publicado en 2020

Blood flow is required for rapid endothelial cell damage induced by a snake venom hemorrhagic metalloproteinase

scientific article published on 09 December 2005

Bothrops asper Hemorrhagic Proteinases

Bothrops asper Metalloproteinase BaP1

Bothrops asper hemorrhagic proteinases

Bothrops asper metalloproteinase BaP1 is inhibited by alpha(2)-macroglobulin and mouse serum and does not induce systemic hemorrhage or coagulopathy

artículo científico publicado en 2004

Brucella abortus uses a stealthy strategy to avoid activation of the innate immune system during the onset of infection

artículo científico publicado en 2007

Characterization of 'basparin A,' a prothrombin-activating metalloproteinase, from the venom of the snake Bothrops asper that inhibits platelet aggregation and induces defibrination and thrombosis

artículo científico publicado en 2003

Characterization of events associated with apoptosis/anoikis induced by snake venom metalloproteinase BaP1 on human endothelial cells

artículo científico publicado en 2005

Coagulopathy induced by viperid snake venoms in a murine model: Comparison of standard coagulation tests and rotational thromboelastometry

artículo científico publicado en 2022

Comparison of biochemical and cytotoxic activities of extracts obtained from dorsal spines and caudal fin of adult and juvenile non-native Caribbean lionfish (Pterois volitans/miles).

artículo científico publicado en 2017

Comparison of venom composition and biological activities of the subspecies Crotalus lepidus lepidus, Crotalus lepidus klauberi and Crotalus lepidus morulus from Mexico

artículo científico publicado en 2013

Correction: Poor Regenerative Outcome after Skeletal Muscle Necrosis Induced by Bothrops asper Venom: Alterations in Microvasculature and Nerves

artículo científico publicado en 2011

Corrigendum to “Neutralization of Bothrops asper venom by antibodies, natural products and synthetic drugs: Contributions to understanding snakebite envenomings and their treatment” published in Toxicon 54 (7), (2009), 1012–1028

scholarly article by Bruno Lomonte et al published June 2010 in Toxicon

Discovery of small molecule inhibitors for the snake venom metalloprotease BaP1 using in silico and in vitro tests

artículo científico publicado en 2017

Effect of the metalloproteinase inhibitor batimastat in the systemic toxicity induced by Bothrops asper snake venom: understanding the role of metalloproteinases in envenomation

artículo científico publicado en 2004

Effects of PI and PIII Snake Venom Haemorrhagic Metalloproteinases on the Microvasculature: A Confocal Microscopy Study on the Mouse Cremaster Muscle

artículo científico publicado en 2016

Efficacy of IgG and F(ab′)2 Antivenoms to Neutralize Snake Venom-induced Local Tissue Damage as Assessed by the Proteomic Analysis of Wound Exudate

artículo científico publicado en 2011

Experimental pathology of local tissue damage induced by Bothrops asper snake venom

artículo científico publicado en 2009

Experimental pathophysiology of systemic alterations induced by Bothrops asper snake venom

artículo científico publicado en 2009

Extracts of Renealmia alpinia (Rottb.) MAAS Protect against Lethality and Systemic Hemorrhage Induced by Bothrops asper Venom: Insights from a Model with Extract Administration before Venom Injection

artículo científico publicado en 2015

Glycolic acid inhibits enzymatic, hemorrhagic and edema-inducing activities of BaP1, a P–I metalloproteinase from Bothrops asper snake venom: Insights from docking and molecular modeling ⬇️

artículo científico publicado el 30 de mayo de 2013

Hemorrhage Caused by Snake Venom Metalloproteinases: A Journey of Discovery and Understanding

artículo científico publicado en 2016

Hemorrhage induced by snake venom metalloproteinases: biochemical and biophysical mechanisms involved in microvessel damage

artículo científico publicado en 2005

Hemorrhagic and procoagulant P-III snake venom metalloproteinases differ in their binding to the microvasculature of mouse cremaster muscle

artículo científico publicado en 2020

Homogenates of skeletal muscle injected with snake venom inhibit myogenic differentiation in cell culture

article

Identification of new snake venom metalloproteinase inhibitors using compound screening and rational Peptide design

artículo científico publicado en 2012

Increments in cytokines and matrix metalloproteinases in skeletal muscle after injection of tissue-damaging toxins from the venom of the snake Bothrops asper

artículo científico publicado en 2002

Inflammatory effects of BaP1 a metalloproteinase isolated from Bothrops asper snake venom: leukocyte recruitment and release of cytokines

artículo científico publicado en 2006

Interaction of snake venom metalloproteinases with type IV collagen: Role of the different domains in target biding

artículo científico publicado en 2020

Isolation and biochemical, functional and structural characterization of a novel L-amino acid oxidase from Lachesis muta snake venom

artículo científico publicado en 2012

Isolation and biological characterization of Batx-I, a weak hemorrhagic and fibrinogenolytic PI metalloproteinase from Colombian Bothrops atrox venom

artículo científico publicado en 2010

Isolation and characterization of four medium-size disintegrins from the venoms of Central American viperid snakes of the genera Atropoides, Bothrops, Cerrophidion and Crotalus

artículo científico publicado en 2014

Key events in microvascular damage induced by snake venom hemorrhagic metalloproteinases

artículo científico publicado en 2011

Local and systemic pathophysiological alterations induced by a serine proteinase from the venom of the snake Bothrops jararacussu

scientific article published on 05 January 2007

Metalloproteinases in disease: identification of biomarkers of tissue damage through proteomics

artículo científico publicado en 2018

Muscle Tissue Damage Induced by the Venom of Bothrops asper: Identification of Early and Late Pathological Events through Proteomic Analysis

artículo científico publicado en 2016

Myotoxic and hemorrhagic effects of fractions obtained from the venom of lionfish (pterois volitans) in mice and identification of potentially toxic components

artículo científico publicado en 2020

Neutralization of Bothrops asper venom by antibodies, natural products and synthetic drugs: contributions to understanding snakebite envenomings and their treatment

artículo científico publicado en 2009

Novel Catalytically-Inactive PII Metalloproteinases from a Viperid Snake Venom with Substitutions in the Canonical Zinc-Binding Motif

artículo científico publicado en 2016

Peptidomimetic hydroxamate metalloproteinase inhibitors abrogate local and systemic toxicity induced by Echis ocellatus (saw-scaled) snake venom

artículo científico publicado en 2017

Platelets support a protective immune response to LCMV by preventing splenic necrosis

artículo científico publicado en 2012

Poor regenerative outcome after skeletal muscle necrosis induced by Bothrops asper venom: alterations in microvasculature and nerves

artículo científico publicado en 2011

Preclinical evaluation of the neutralizing ability of a monospecific antivenom for the treatment of envenomings by Bothrops lanceolatus in Martinique

scholarly article by Dabor Resiere et al published June 2018 in Toxicon

Protease Activity Profiling of Snake Venoms Using High-Throughput Peptide Screening

scholarly article by Konstantinos Kalogeropoulos et al published 19 March 2019 in Toxins

Proteomic Analysis of Human Blister Fluids Following Envenomation by Three Snake Species in India: Differential Markers for Venom Mechanisms of Action.

artículo científico publicado en 2019

Proteomic analysis of Bothrops pirajai snake venom and characterization of BpirMP, a new P-I metalloproteinase

artículo científico publicado en 2013

Proteomic and functional profiling of the venom of Bothrops ayerbei from Cauca, Colombia, reveals striking interspecific variation with Bothrops asper venom

artículo científico publicado en 2013

Proteomics of Wound Exudate in Snake Venom-Induced Pathology: Search for Biomarkers To Assess Tissue Damage and Therapeutic Success

article

Pulmonary hemorrhage induced by jararhagin, a metalloproteinase from Bothrops jararaca snake venom

artículo científico publicado en 2003

Resistance of South American opossums to vWF-binding venom C-type lectins

scientific article published on 02 March 2020

Role of collagens and perlecan in microvascular stability: exploring the mechanism of capillary vessel damage by snake venom metalloproteinases

artículo científico publicado en 2011

Site mutation of residues in a loop surrounding the active site of a PI snake venom metalloproteinase abrogates its hemorrhagic activity

scientific article published on 28 March 2019

Skin pathology induced by snake venom metalloproteinase: acute damage, revascularization, and re-epithelization in a mouse ear model

artículo científico publicado en 2008

Snake venomics of the Lesser Antillean pit vipers Bothrops caribbaeus and Bothrops lanceolatus: correlation with toxicological activities and immunoreactivity of a heterologous antivenom

artículo científico publicado en 2008

Substitutions of residues in a loop surrounding the active site of a P-I snake venom metalloproteinase abrogates its hemorrhagic activity

artículo científico publicado en 2020

Synthetic libraries of shark vNAR domains with different cysteine numbers within the CDR3

scientific article published on 17 June 2019

Systemic effects induced by the venom of the snake Bothrops caribbaeus in a murine model

artículo científico publicado en 2012

Systemic vascular leakage induced in mice by Russell's viper venom from Pakistan

artículo científico publicado en 2018

The Search for Natural and Synthetic Inhibitors That Would Complement Antivenoms as Therapeutics for Snakebite Envenoming

artículo científico publicado en 2021

The lethality test used for estimating the potency of antivenoms against Bothrops asper snake venom: Pathophysiological mechanisms, prophylactic analgesia, and a surrogate in vitro assay

article

Thrombocytopenia and platelet hypoaggregation induced by Bothrops asper snake venom

scholarly article by Mónica Soto et al published 2005 in Thrombosis and Haemostasis

Thrombocytopenia and platelet hypoaggregation induced by Bothrops asper snake venom. Toxins involved and their contribution to metalloproteinase-induced pulmonary hemorrhage

artículo científico publicado en 2005

Tissue localization and extracellular matrix degradation by PI, PII and PIII snake venom metalloproteinases: clues on the mechanisms of venom-induced hemorrhage

artículo científico publicado en 2015

Tissue pathology induced by snake venoms: How to understand a complex pattern of alterations from a systems biology perspective?

artículo científico publicado en 2009

Trends in snakebite envenomation therapy: scientific, technological and public health considerations

artículo científico publicado en 2007

Understanding structural and functional aspects of PII snake venom metalloproteinases: characterization of BlatH1, a hemorrhagic dimeric enzyme from the venom of Bothriechis lateralis

artículo científico publicado en 2014

Unravelling the pathophysiology of vascular leakage induced by Daboia russelli snake venom

artículo científico publicado en 2020

Unresolved issues in the understanding of the pathogenesis of local tissue damage induced by snake venoms

artículo científico publicado en 2018

Viperid Envenomation Wound Exudate Contributes to Increased Vascular Permeability via a DAMPs/TLR-4 Mediated Pathway

artículo científico publicado en 2016

Why is Skeletal Muscle Regeneration Impaired after Myonecrosis Induced by Viperid Snake Venoms?

artículo científico publicado en 2018

Wound exudate as a proteomic window to reveal different mechanisms of tissue damage by snake venom toxins

artículo científico publicado en 2009

Lista de obras de

192. Action of Venom Metalloproteinases on Basement Membranes: Pathogenesis of Hemorrhage and Blistering in Snakebite Envenomings

A Comprehensive View of the Structural and Functional Alterations of Extracellular Matrix by Snake Venom Metalloproteinases (SVMPs): Novel Perspectives on the Pathophysiology of Envenoming

A representative metalloprotease induces PGE2 synthesis in fibroblast-like synoviocytes via the NF-κB/COX-2 pathway with amplification by IL-1β and the EP4 receptor

Amino acid sequence and crystal structure of BaP1, a metalloproteinase from Bothrops asper snake venom that exerts multiple tissue-damaging activities

Analysis of wound exudates reveals differences in the patterns of tissue damage and inflammation induced by the venoms of Daboia russelii and Bothrops asper in mice

Anti-human erythrocyte antibodies in horse-derived antivenoms used in the treatment of snakebite envenomations

Assessment of metalloproteinase inhibitors clodronate and doxycycline in the neutralization of hemorrhage and coagulopathy induced by Bothrops asper snake venom

Basement membrane degradation and inflammation play a role in the pulmonary hemorrhage induced by a P-III snake venom metalloproteinase

Biochemical and biological characterization of two serine proteinases from Colombian Crotalus durissus cumanensis snake venom

Biomolecular investigation into systemic vascular leakage and kidney dysfunction induced by Russell's viper: A unique type of vascular toxicity and pathophysiology in viperid envenomings

Blood flow is required for rapid endothelial cell damage induced by a snake venom hemorrhagic metalloproteinase

Bothrops asper Hemorrhagic Proteinases

Bothrops asper Metalloproteinase BaP1

Bothrops asper hemorrhagic proteinases

Bothrops asper metalloproteinase BaP1 is inhibited by alpha(2)-macroglobulin and mouse serum and does not induce systemic hemorrhage or coagulopathy

Brucella abortus uses a stealthy strategy to avoid activation of the innate immune system during the onset of infection

Characterization of 'basparin A,' a prothrombin-activating metalloproteinase, from the venom of the snake Bothrops asper that inhibits platelet aggregation and induces defibrination and thrombosis

Characterization of events associated with apoptosis/anoikis induced by snake venom metalloproteinase BaP1 on human endothelial cells

Coagulopathy induced by viperid snake venoms in a murine model: Comparison of standard coagulation tests and rotational thromboelastometry

Comparison of biochemical and cytotoxic activities of extracts obtained from dorsal spines and caudal fin of adult and juvenile non-native Caribbean lionfish (Pterois volitans/miles).

Comparison of venom composition and biological activities of the subspecies Crotalus lepidus lepidus, Crotalus lepidus klauberi and Crotalus lepidus morulus from Mexico

Correction: Poor Regenerative Outcome after Skeletal Muscle Necrosis Induced by Bothrops asper Venom: Alterations in Microvasculature and Nerves

Corrigendum to “Neutralization of Bothrops asper venom by antibodies, natural products and synthetic drugs: Contributions to understanding snakebite envenomings and their treatment” published in Toxicon 54 (7), (2009), 1012–1028

Discovery of small molecule inhibitors for the snake venom metalloprotease BaP1 using in silico and in vitro tests

Effect of the metalloproteinase inhibitor batimastat in the systemic toxicity induced by Bothrops asper snake venom: understanding the role of metalloproteinases in envenomation

Effects of PI and PIII Snake Venom Haemorrhagic Metalloproteinases on the Microvasculature: A Confocal Microscopy Study on the Mouse Cremaster Muscle

Efficacy of IgG and F(ab′)2 Antivenoms to Neutralize Snake Venom-induced Local Tissue Damage as Assessed by the Proteomic Analysis of Wound Exudate

Experimental pathology of local tissue damage induced by Bothrops asper snake venom

Experimental pathophysiology of systemic alterations induced by Bothrops asper snake venom

Extracts of Renealmia alpinia (Rottb.) MAAS Protect against Lethality and Systemic Hemorrhage Induced by Bothrops asper Venom: Insights from a Model with Extract Administration before Venom Injection

Glycolic acid inhibits enzymatic, hemorrhagic and edema-inducing activities of BaP1, a P–I metalloproteinase from Bothrops asper snake venom: Insights from docking and molecular modeling ⬇️

Hemorrhage Caused by Snake Venom Metalloproteinases: A Journey of Discovery and Understanding

Hemorrhage induced by snake venom metalloproteinases: biochemical and biophysical mechanisms involved in microvessel damage

Hemorrhagic and procoagulant P-III snake venom metalloproteinases differ in their binding to the microvasculature of mouse cremaster muscle

Homogenates of skeletal muscle injected with snake venom inhibit myogenic differentiation in cell culture

Identification of new snake venom metalloproteinase inhibitors using compound screening and rational Peptide design

Increments in cytokines and matrix metalloproteinases in skeletal muscle after injection of tissue-damaging toxins from the venom of the snake Bothrops asper

Inflammatory effects of BaP1 a metalloproteinase isolated from Bothrops asper snake venom: leukocyte recruitment and release of cytokines

Interaction of snake venom metalloproteinases with type IV collagen: Role of the different domains in target biding

Isolation and biochemical, functional and structural characterization of a novel L-amino acid oxidase from Lachesis muta snake venom

Isolation and biological characterization of Batx-I, a weak hemorrhagic and fibrinogenolytic PI metalloproteinase from Colombian Bothrops atrox venom

Isolation and characterization of four medium-size disintegrins from the venoms of Central American viperid snakes of the genera Atropoides, Bothrops, Cerrophidion and Crotalus

Key events in microvascular damage induced by snake venom hemorrhagic metalloproteinases

Local and systemic pathophysiological alterations induced by a serine proteinase from the venom of the snake Bothrops jararacussu

Metalloproteinases in disease: identification of biomarkers of tissue damage through proteomics

Muscle Tissue Damage Induced by the Venom of Bothrops asper: Identification of Early and Late Pathological Events through Proteomic Analysis

Myotoxic and hemorrhagic effects of fractions obtained from the venom of lionfish (pterois volitans) in mice and identification of potentially toxic components

Neutralization of Bothrops asper venom by antibodies, natural products and synthetic drugs: contributions to understanding snakebite envenomings and their treatment

Novel Catalytically-Inactive PII Metalloproteinases from a Viperid Snake Venom with Substitutions in the Canonical Zinc-Binding Motif

Peptidomimetic hydroxamate metalloproteinase inhibitors abrogate local and systemic toxicity induced by Echis ocellatus (saw-scaled) snake venom

Platelets support a protective immune response to LCMV by preventing splenic necrosis

Poor regenerative outcome after skeletal muscle necrosis induced by Bothrops asper venom: alterations in microvasculature and nerves

Preclinical evaluation of the neutralizing ability of a monospecific antivenom for the treatment of envenomings by Bothrops lanceolatus in Martinique

Protease Activity Profiling of Snake Venoms Using High-Throughput Peptide Screening

Proteomic Analysis of Human Blister Fluids Following Envenomation by Three Snake Species in India: Differential Markers for Venom Mechanisms of Action.

Proteomic analysis of Bothrops pirajai snake venom and characterization of BpirMP, a new P-I metalloproteinase

Proteomic and functional profiling of the venom of Bothrops ayerbei from Cauca, Colombia, reveals striking interspecific variation with Bothrops asper venom

Proteomics of Wound Exudate in Snake Venom-Induced Pathology: Search for Biomarkers To Assess Tissue Damage and Therapeutic Success

Pulmonary hemorrhage induced by jararhagin, a metalloproteinase from Bothrops jararaca snake venom

Resistance of South American opossums to vWF-binding venom C-type lectins

Role of collagens and perlecan in microvascular stability: exploring the mechanism of capillary vessel damage by snake venom metalloproteinases

Site mutation of residues in a loop surrounding the active site of a PI snake venom metalloproteinase abrogates its hemorrhagic activity

Skin pathology induced by snake venom metalloproteinase: acute damage, revascularization, and re-epithelization in a mouse ear model

Snake venomics of the Lesser Antillean pit vipers Bothrops caribbaeus and Bothrops lanceolatus: correlation with toxicological activities and immunoreactivity of a heterologous antivenom

Substitutions of residues in a loop surrounding the active site of a P-I snake venom metalloproteinase abrogates its hemorrhagic activity

Synthetic libraries of shark vNAR domains with different cysteine numbers within the CDR3

Systemic effects induced by the venom of the snake Bothrops caribbaeus in a murine model

Systemic vascular leakage induced in mice by Russell's viper venom from Pakistan

The Search for Natural and Synthetic Inhibitors That Would Complement Antivenoms as Therapeutics for Snakebite Envenoming

The lethality test used for estimating the potency of antivenoms against Bothrops asper snake venom: Pathophysiological mechanisms, prophylactic analgesia, and a surrogate in vitro assay

Thrombocytopenia and platelet hypoaggregation induced by Bothrops asper snake venom

Thrombocytopenia and platelet hypoaggregation induced by Bothrops asper snake venom. Toxins involved and their contribution to metalloproteinase-induced pulmonary hemorrhage

Tissue localization and extracellular matrix degradation by PI, PII and PIII snake venom metalloproteinases: clues on the mechanisms of venom-induced hemorrhage

Tissue pathology induced by snake venoms: How to understand a complex pattern of alterations from a systems biology perspective?

Trends in snakebite envenomation therapy: scientific, technological and public health considerations

Understanding structural and functional aspects of PII snake venom metalloproteinases: characterization of BlatH1, a hemorrhagic dimeric enzyme from the venom of Bothriechis lateralis

Unravelling the pathophysiology of vascular leakage induced by Daboia russelli snake venom

Unresolved issues in the understanding of the pathogenesis of local tissue damage induced by snake venoms

Viperid Envenomation Wound Exudate Contributes to Increased Vascular Permeability via a DAMPs/TLR-4 Mediated Pathway