Lista de obras - Ana J García-Sáez - Dominio Público Uruguay

7th Tuscany Retreat on Cancer Research: genetic profiling, resistance mechanism and novel treatment concepts in cancer.

artículo científico publicado en 2011

A new perspective on membrane-embedded Bax oligomers using DEER and bioresistant orthogonal spin labels

artículo científico publicado en 2019

A single herpesvirus protein can mediate vesicle formation in the nuclear envelope

artículo científico publicado en 2015

Apoptotic foci at mitochondria: in and around Bax pores

artículo científico publicado en 2017

Apoptotic stress induces Bax-dependent, caspase-independent redistribution of LINC complex nesprins

scientific article published on 18 September 2020

Assembling the puzzle: Oligomerization of α-pore forming proteins in membranes

artículo científico publicado en 2015

Atomic Force Microscopy Imaging and Force Spectroscopy of Supported Lipid Bilayers

artículo científico publicado en 2015

Automated analysis of giant unilamellar vesicles using circular Hough transformation.

artículo científico publicado en 2014

BCL-2-family protein tBID can act as a BAX-like effector of apoptosis

artículo científico publicado en 2021

Bax assembly into rings and arcs in apoptotic mitochondria is linked to membrane pores.

artículo científico

Bax monomers form dimer units in the membrane that further self-assemble into multiple oligomeric species

artículo científico publicado en 2015

Cardiolipin effects on membrane structure and dynamics.

artículo científico publicado en 2013

DRP1 interacts directly with BAX to induce its activation and apoptosis

artículo científico publicado en 2022

Destabilization exerted by peptides derived from the membrane-proximal external region of HIV-1 gp41 in lipid vesicles supporting fluid phase coexistence.

artículo científico publicado en 2011

Determinants of BH3 Sequence Specificity for the Disruption of Bcl-xL/cBid Complexes in Membranes.

artículo científico publicado en 2017

Differences in activity of actinoporins are related with the hydrophobicity of their N-terminus

artículo científico publicado en 2015

Drp1 modulates mitochondrial stress responses to mitotic arrest

artículo científico publicado en 2020

Drp1 polymerization stabilizes curved tubular membranes similar to those of constricted mitochondria.

artículo científico publicado en 2017

Dynamic interaction of cBid with detergents, liposomes and mitochondria.

artículo científico publicado en 2012

Dynamin-related protein 1 (Drp1) promotes structural intermediates of membrane division

artículo científico publicado en 2014

Dynein light chain binding determines complex formation and posttranslational stability of the Bcl-2 family members Bmf and Bim

artículo científico publicado en 2019

Fluorescence correlation spectroscopy for the study of membrane dynamics and organization in giant unilamellar vesicles

scientific article published on 01 January 2010

Formation of disulfide bridges drives oligomerization, membrane pore formation, and translocation of fibroblast growth factor 2 to cell surfaces.

artículo científico publicado en 2015

Giant unilamellar vesicles (GUVs) as a new tool for analysis of caspase-8/Bid-FL complex binding to cardiolipin and its functional activity.

artículo científico publicado en 2010

Lipids glue BAK dimers together

artículo científico publicado en 2020

MERLIN: a novel BRET-based proximity biosensor for studying mitochondria-ER contact sites

scientific article published on 09 December 2019

MIM through MOM: the awakening of Bax and Bak pores

artículo científico publicado en 2018

MLKL promotes cellular differentiation in myeloid leukemia by facilitating the release of G-CSF

artículo científico publicado en 2021

Mechanistic differences in the membrane activity of Bax and Bcl-xL correlate with their opposing roles in apoptosis.

artículo científico publicado en 2013

Membrane Disintegration Caused by the Steroid Saponin Digitonin Is Related to the Presence of Cholesterol.

artículo científico publicado en 2015

Membrane promotes tBID interaction with BCL(XL).

artículo científico publicado en 2009

Membrane-insertion fragments of Bcl-xL, Bax, and Bid

artículo científico publicado en 2004

Membranes in motion: mitochondrial dynamics and their role in apoptosis.

artículo científico publicado en 2014

Mitochondrial alterations in apoptosis.

artículo científico publicado en 2014

Mitochondrial residence of the apoptosis inducer BAX is more important than BAX oligomerization in promoting membrane permeabilization

artículo científico publicado en 2020

Molecular mechanisms of cell death: recommendations of the Nomenclature Committee on Cell Death 2018.

artículo científico publicado en 2018

More Than a Pore: The Interplay of Pore-Forming Proteins and Lipid Membranes.

artículo científico

New biophysical methods to study the membrane activity of Bcl-2 proteins.

artículo científico publicado en 2014

Peptides corresponding to helices 5 and 6 of Bax can independently form large lipid pores

artículo científico publicado en 2006

Peptides derived from apoptotic Bax and Bid reproduce the poration activity of the parent full-length proteins

artículo científico publicado en 2005

Peptides in apoptosis research.

artículo científico publicado en 2002

Permeabilization of the Outer Mitochondrial Membrane by Bcl-2 Proteins ⬇️

artículo científico publicado el 1 de enero de 2010

Phosphatidylinositol 4,5-bisphosphate (PI(4,5)P2)-dependent oligomerization of fibroblast growth factor 2 (FGF2) triggers the formation of a lipidic membrane pore implicated in unconventional secretion.

artículo científico publicado en 2012

Pore formation by a Bax-derived peptide: effect on the line tension of the membrane probed by AFM.

artículo científico publicado en 2007

Pore formation in regulated cell death

artículo científico publicado en 2020

Pores formed by Baxα5 relax to a smaller size and keep at equilibrium ⬇️

artículo científico publicado el 3 de noviembre de 2010

Proapoptotic Bax and Bak proteins form stable protein-permeable pores of tunable size

artículo científico publicado en 2013

Quantitative analysis of super-resolved structures using ASAP

scientific article published on 01 July 2019

Quantitative interactome of a membrane Bcl-2 network identifies a hierarchy of complexes for apoptosis regulation.

artículo científico publicado en 2017

Scanning fluorescence correlation spectroscopy on biomembranes.

artículo científico publicado en 2015

Single event visualization of unconventional secretion of FGF2

artículo científico publicado en 2018

Structural model of active Bax at the membrane.

artículo científico publicado en 2014

TAT-RasGAP<sub>317-326</sub> kills cells by targeting inner-leaflet-enriched phospholipids

artículo científico publicado en 2020

The Mysteries around the BCL-2 Family Member BOK

scientific article published on 04 December 2020

Toxicity of an α-pore-forming toxin depends on the assembly mechanism on the target membrane as revealed by single molecule imaging

artículo científico publicado en 2014

cBid, Bax and Bcl-xL exhibit opposite membrane remodeling activities.

artículo científico publicado en 2016

Lista de obras de Ana J García-Sáez

7th Tuscany Retreat on Cancer Research: genetic profiling, resistance mechanism and novel treatment concepts in cancer.

A new perspective on membrane-embedded Bax oligomers using DEER and bioresistant orthogonal spin labels

A single herpesvirus protein can mediate vesicle formation in the nuclear envelope

Apoptotic foci at mitochondria: in and around Bax pores

Apoptotic stress induces Bax-dependent, caspase-independent redistribution of LINC complex nesprins

Assembling the puzzle: Oligomerization of α-pore forming proteins in membranes

Atomic Force Microscopy Imaging and Force Spectroscopy of Supported Lipid Bilayers

Automated analysis of giant unilamellar vesicles using circular Hough transformation.

BCL-2-family protein tBID can act as a BAX-like effector of apoptosis

Bax assembly into rings and arcs in apoptotic mitochondria is linked to membrane pores.

Bax monomers form dimer units in the membrane that further self-assemble into multiple oligomeric species

Cardiolipin effects on membrane structure and dynamics.

DRP1 interacts directly with BAX to induce its activation and apoptosis

Destabilization exerted by peptides derived from the membrane-proximal external region of HIV-1 gp41 in lipid vesicles supporting fluid phase coexistence.

Determinants of BH3 Sequence Specificity for the Disruption of Bcl-xL/cBid Complexes in Membranes.

Differences in activity of actinoporins are related with the hydrophobicity of their N-terminus

Drp1 modulates mitochondrial stress responses to mitotic arrest

Drp1 polymerization stabilizes curved tubular membranes similar to those of constricted mitochondria.

Dynamic interaction of cBid with detergents, liposomes and mitochondria.

Dynamin-related protein 1 (Drp1) promotes structural intermediates of membrane division

Dynein light chain binding determines complex formation and posttranslational stability of the Bcl-2 family members Bmf and Bim

Fluorescence correlation spectroscopy for the study of membrane dynamics and organization in giant unilamellar vesicles

Formation of disulfide bridges drives oligomerization, membrane pore formation, and translocation of fibroblast growth factor 2 to cell surfaces.

Giant unilamellar vesicles (GUVs) as a new tool for analysis of caspase-8/Bid-FL complex binding to cardiolipin and its functional activity.

Lipids glue BAK dimers together

MERLIN: a novel BRET-based proximity biosensor for studying mitochondria-ER contact sites

MIM through MOM: the awakening of Bax and Bak pores

MLKL promotes cellular differentiation in myeloid leukemia by facilitating the release of G-CSF

Mechanistic differences in the membrane activity of Bax and Bcl-xL correlate with their opposing roles in apoptosis.

Membrane Disintegration Caused by the Steroid Saponin Digitonin Is Related to the Presence of Cholesterol.

Membrane promotes tBID interaction with BCL(XL).

Membrane-insertion fragments of Bcl-xL, Bax, and Bid

Membranes in motion: mitochondrial dynamics and their role in apoptosis.

Mitochondrial alterations in apoptosis.

Mitochondrial residence of the apoptosis inducer BAX is more important than BAX oligomerization in promoting membrane permeabilization

Molecular mechanisms of cell death: recommendations of the Nomenclature Committee on Cell Death 2018.

More Than a Pore: The Interplay of Pore-Forming Proteins and Lipid Membranes.

New biophysical methods to study the membrane activity of Bcl-2 proteins.

Peptides corresponding to helices 5 and 6 of Bax can independently form large lipid pores

Peptides derived from apoptotic Bax and Bid reproduce the poration activity of the parent full-length proteins

Peptides in apoptosis research.

Permeabilization of the Outer Mitochondrial Membrane by Bcl-2 Proteins ⬇️

Phosphatidylinositol 4,5-bisphosphate (PI(4,5)P2)-dependent oligomerization of fibroblast growth factor 2 (FGF2) triggers the formation of a lipidic membrane pore implicated in unconventional secretion.

Pore formation by a Bax-derived peptide: effect on the line tension of the membrane probed by AFM.

Pore formation in regulated cell death

Pores formed by Baxα5 relax to a smaller size and keep at equilibrium ⬇️

Proapoptotic Bax and Bak proteins form stable protein-permeable pores of tunable size

Quantitative analysis of super-resolved structures using ASAP

Quantitative interactome of a membrane Bcl-2 network identifies a hierarchy of complexes for apoptosis regulation.

Scanning fluorescence correlation spectroscopy on biomembranes.

Single event visualization of unconventional secretion of FGF2

Structural model of active Bax at the membrane.

TAT-RasGAP<sub>317-326</sub> kills cells by targeting inner-leaflet-enriched phospholipids

The Mysteries around the BCL-2 Family Member BOK

Toxicity of an α-pore-forming toxin depends on the assembly mechanism on the target membrane as revealed by single molecule imaging

cBid, Bax and Bcl-xL exhibit opposite membrane remodeling activities.