Lista de obras -

3-position modification of myo-inositol 1,4,5-trisphosphate: consequences for intracellular Ca2+ mobilisation and enzyme recognition.

artículo científico publicado en 1992

A cell-permeable tool for analysing APP intracellular domain function and manipulation of PIKfyve activity.

artículo científico publicado en 2016

A comparison between muscarinic receptor occupancy, inositol 1,4,5-trisphosphate accumulation and Ca2+ mobilization in permeabilized SH-SY5Y neuroblastoma cells

artículo científico publicado en 1994

A novel mechanism for the anticancer activity of aspirin and salicylates

scientific article published on 29 January 2019

Antagonists show GTP-sensitive high-affinity binding to the sigma-1 receptor

artículo científico publicado en 2011

Are fluoxetine's effects due to sigma-1 receptor agonism?

artículo científico publicado en 2016

Benzene polyphosphates as tools for cell signalling: inhibition of inositol 1,4,5-trisphosphate 5-phosphatase and interaction with the PH domain of protein kinase Balpha.

artículo científico publicado en 2008

Biological variability in the structures of diphosphoinositol polyphosphates in Dictyostelium discoideum and mammalian cells ⬇️

artículo científico publicado el 15 de octubre de 1997

Ca2(+)-mobilising properties of synthetic fluoro-analogues of myo-inositol 1,4,5-trisphosphate and their interaction with myo-inositol 1,4,5-trisphosphate 3-kinase and 5-phosphatase

artículo científico publicado en 1990

Characterisation of a bis(5'-nucleosyl)-tetraphosphatase (asymmetrical) from Drosophila melanogaster.

artículo científico publicado en 2007

Characterizing Enzymes of the Diphosphoinositol Polyphosphate Phosphohydrolase (DIPP) Family

artículo científico publicado en 2020

Cloning and characterisation of hAps1 and hAps2, human diadenosine polyphosphate-metabolising Nudix hydrolases

artículo científico publicado en 2002

Dipentylammonium Binds to the Sigma-1 Receptor and Protects Against Glutamate Toxicity, Attenuates Dopamine Toxicity and Potentiates Neurite Outgrowth in Various Cultured Cell Lines

article

Diphosphoinositol polyphosphates: the final frontier for inositide research?

artículo científico publicado en 1999

Disruption and overexpression of the Schizosaccharomyces pombe aps1 gene, and effects on growth rate, morphology and intracellular diadenosine 5',5"'-P1,P5-pentaphosphate and diphosphoinositol polyphosphate concentrations

artículo científico publicado en 2003

Fibrinogen - a possible extracellular target for inositol phosphates

artículo científico publicado en 2012

Interaction of synthetic D-6-deoxy-myo-inositol 1,4,5-trisphosphate with the Ca2(+)-releasing D-myo-inositol 1,4,5-trisphosphate receptor, and the metabolic enzymes 5-phosphatase and 3-kinase

artículo científico publicado en 1991

Molecular cloning and expression of a rat hepatic multiple inositol polyphosphate phosphatase ⬇️

artículo científico publicado el 15 de noviembre de 1997

Muscarinic receptors, phosphoinositide metabolism and intracellular calcium in neuronal cells

artículo científico publicado en 1992

Neuronal muscarinic receptors and phosphoinositide metabolism ⬇️

artículo científico publicado el 1 de abril de 1991

Nudix hydrolases that degrade dinucleoside and diphosphoinositol polyphosphates also have 5-phosphoribosyl 1-pyrophosphate (PRPP) pyrophosphatase activity that generates the glycolytic activator ribose 1,5-bisphosphate

artículo científico publicado en 2002

Protocols for regulation and study of diphosphoinositol polyphosphates.

artículo científico publicado en 2004

Simple ammonium salts acting on sigma-1 receptors yield potential treatments for cancer and depression

artículo científico publicado en 2020

Small molecule antagonists of the sigma-1 receptor cause selective release of the death program in tumor and self-reliant cells and inhibit tumor growth in vitro and in vivo

artículo científico publicado en 2004

Structural insights into the regulation of PDK1 by phosphoinositides and inositol phosphates.

artículo científico publicado en 2004

Synthetic D- and L-enantiomers of 2,2-difluoro-2-deoxy-myo-inositol 1,4,5-trisphosphate interact differently with myo-inositol 1,4,5-trisphosphate binding proteins: identification of a potent small molecule 3-kinase inhibitor

artículo científico publicado el 1 de enero de 1992

The Cytotoxicity and Synergistic Potential of Aspirin and Aspirin Analogues Towards Oesophageal and Colorectal Cancer

scientific article published on 01 January 2019

The g5R (D250) gene of African swine fever virus encodes a Nudix hydrolase that preferentially degrades diphosphoinositol polyphosphates

artículo científico publicado en 2002

The regulation of membrane to cytosol partitioning of signalling proteins by phosphoinositides and their soluble headgroups

artículo científico publicado en 2005

Turnover of bis-diphosphoinositol tetrakisphosphate in a smooth muscle cell line is regulated by beta 2-adrenergic receptors through a cAMP-mediated, A-kinase-independent mechanism ⬇️

artículo científico publicado el 16 de marzo de 1998

Understanding inositol pyrophosphate metabolism and function: kinetic characterization of the DIPPs

artículo científico publicado en 2013

Lista de obras de

3-position modification of myo-inositol 1,4,5-trisphosphate: consequences for intracellular Ca2+ mobilisation and enzyme recognition.

A cell-permeable tool for analysing APP intracellular domain function and manipulation of PIKfyve activity.

A comparison between muscarinic receptor occupancy, inositol 1,4,5-trisphosphate accumulation and Ca2+ mobilization in permeabilized SH-SY5Y neuroblastoma cells

A novel mechanism for the anticancer activity of aspirin and salicylates

Antagonists show GTP-sensitive high-affinity binding to the sigma-1 receptor

Are fluoxetine's effects due to sigma-1 receptor agonism?

Benzene polyphosphates as tools for cell signalling: inhibition of inositol 1,4,5-trisphosphate 5-phosphatase and interaction with the PH domain of protein kinase Balpha.

Biological variability in the structures of diphosphoinositol polyphosphates in Dictyostelium discoideum and mammalian cells ⬇️

Ca2(+)-mobilising properties of synthetic fluoro-analogues of myo-inositol 1,4,5-trisphosphate and their interaction with myo-inositol 1,4,5-trisphosphate 3-kinase and 5-phosphatase

Characterisation of a bis(5'-nucleosyl)-tetraphosphatase (asymmetrical) from Drosophila melanogaster.

Characterizing Enzymes of the Diphosphoinositol Polyphosphate Phosphohydrolase (DIPP) Family

Cloning and characterisation of hAps1 and hAps2, human diadenosine polyphosphate-metabolising Nudix hydrolases

Dipentylammonium Binds to the Sigma-1 Receptor and Protects Against Glutamate Toxicity, Attenuates Dopamine Toxicity and Potentiates Neurite Outgrowth in Various Cultured Cell Lines

Diphosphoinositol polyphosphates: the final frontier for inositide research?

Disruption and overexpression of the Schizosaccharomyces pombe aps1 gene, and effects on growth rate, morphology and intracellular diadenosine 5',5"'-P1,P5-pentaphosphate and diphosphoinositol polyphosphate concentrations

Fibrinogen - a possible extracellular target for inositol phosphates

Interaction of synthetic D-6-deoxy-myo-inositol 1,4,5-trisphosphate with the Ca2(+)-releasing D-myo-inositol 1,4,5-trisphosphate receptor, and the metabolic enzymes 5-phosphatase and 3-kinase

Molecular cloning and expression of a rat hepatic multiple inositol polyphosphate phosphatase ⬇️

Muscarinic receptors, phosphoinositide metabolism and intracellular calcium in neuronal cells

Neuronal muscarinic receptors and phosphoinositide metabolism ⬇️

Nudix hydrolases that degrade dinucleoside and diphosphoinositol polyphosphates also have 5-phosphoribosyl 1-pyrophosphate (PRPP) pyrophosphatase activity that generates the glycolytic activator ribose 1,5-bisphosphate

Protocols for regulation and study of diphosphoinositol polyphosphates.

Simple ammonium salts acting on sigma-1 receptors yield potential treatments for cancer and depression

Small molecule antagonists of the sigma-1 receptor cause selective release of the death program in tumor and self-reliant cells and inhibit tumor growth in vitro and in vivo

Structural insights into the regulation of PDK1 by phosphoinositides and inositol phosphates.

Synthetic D- and L-enantiomers of 2,2-difluoro-2-deoxy-myo-inositol 1,4,5-trisphosphate interact differently with myo-inositol 1,4,5-trisphosphate binding proteins: identification of a potent small molecule 3-kinase inhibitor

The Cytotoxicity and Synergistic Potential of Aspirin and Aspirin Analogues Towards Oesophageal and Colorectal Cancer

The g5R (D250) gene of African swine fever virus encodes a Nudix hydrolase that preferentially degrades diphosphoinositol polyphosphates

The regulation of membrane to cytosol partitioning of signalling proteins by phosphoinositides and their soluble headgroups

Turnover of bis-diphosphoinositol tetrakisphosphate in a smooth muscle cell line is regulated by beta 2-adrenergic receptors through a cAMP-mediated, A-kinase-independent mechanism ⬇️

Understanding inositol pyrophosphate metabolism and function: kinetic characterization of the DIPPs

Viral Activation of Interleukin-15 (IL-15): Characterization of a Virus-Inducible Element in the IL-15 Promoter Region