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1,2,6-Thiadiazinones as Novel Narrow Spectrum Calcium/Calmodulin-Dependent Protein Kinase Kinase 2 (CaMKK2) Inhibitors.

artículo científico publicado en 2018

AMP-activated protein kinase complexes containing the β2 regulatory subunit are up-regulated during and contribute to adipogenesis

artículo científico publicado en 2019

AMP-activated protein kinase selectively inhibited by the type II inhibitor SBI-0206965.

artículo científico publicado en 2018

AMP-activated protein kinase subunit interactions: beta1:gamma1 association requires beta1 Thr-263 and Tyr-267.

artículo científico publicado en 2007

AMPK functions as an adenylate charge-regulated protein kinase.

artículo científico

AMPK is a direct adenylate charge-regulated protein kinase.

artículo científico publicado en 2011

AMPK structure and regulation from three angles.

artículo científico publicado en 2007

AMPK-independent pathways regulate skeletal muscle fatty acid oxidation.

artículo científico publicado en 2008

ATP sensitive bi-quinoline activator of the AMP-activated protein kinase.

artículo científico publicado en 2013

ATP synthase inhibitory factor 1 (IF1), a novel myokine, regulates glucose metabolism by AMPK and Akt dual pathways

scientific article published on 31 October 2019

Adipose tissue as an endocrine organ

article

Allosteric regulation of AMP-activated protein kinase by adenylate nucleotides and small-molecule drugs

scientific article published on 18 April 2019

Are genuine changes in protein expression being overlooked? Reassessing Western blotting.

artículo científico publicado en 2009

Author Correction: Increased autophagy in EphrinB2-deficient osteocytes is associated with elevated secondary mineralization and brittle bone

artículo científico publicado en 2019

Autophagy induced during apoptosis degrades mitochondria and inhibits type I interferon secretion.

artículo científico publicado en 2017

Autophosphorylation of CaMKK2 generates autonomous activity that is disrupted by a T85S mutation linked to anxiety and bipolar disorder

artículo científico publicado en 2015

Ca2+/Calmodulin-dependent protein kinase kinase beta is regulated by multisite phosphorylation.

artículo científico publicado en 2011

Cyclin-dependent kinase-mediated phosphorylation of breast cancer metastasis suppressor 1 (BRMS1) affects cell migration.

artículo científico publicado en 2016

DNA-dependent protein kinase regulates lysosomal AMP-dependent protein kinase activation and autophagy

scientific article published on 26 January 2020

Expression and purification of functional recombinant meningococcal transferrin-binding protein A.

artículo científico publicado en 2002

Functional analysis of an R311C variant of Ca2+ -calmodulin-dependent protein kinase kinase-2 (CaMKK2) found as a de novo mutation in a patient with bipolar disorder

scientific article published on 25 March 2020

Functional characterization of human duodenal cytochrome b (Cybrd1): Redox properties in relation to iron and ascorbate metabolism.

artículo científico publicado en 2007

Homology modelling of transferrin-binding protein A from Neisseria meningitidis.

artículo científico publicado en 2005

Impact of Genetic Variation on Human CaMKK2 Regulation by Ca2+-Calmodulin and Multisite Phosphorylation.

artículo científico publicado en 2017

Import of extracellular ATP in yeast and man modulates AMPK and TORC1 signalling

artículo científico publicado en 2019

In Depth Analysis of Kinase Cross Screening Data to Identify CAMKK2 Inhibitory Scaffolds

artículo científico publicado en 2020

Increased autophagy in EphrinB2-deficient osteocytes is associated with elevated secondary mineralization and brittle bone

artículo científico publicado en 2019

Inhibition of AMP-Activated Protein Kinase at the Allosteric Drug-Binding Site Promotes Islet Insulin Release.

artículo científico publicado en 2015

Insight into the structure and function of the transferrin receptor from Neisseria meningitidis using microcalorimetric techniques

scientific article published on 05 February 2003

Long-chain fatty acyl-CoA esters regulate metabolism via allosteric control of AMPK β1 isoforms

artículo científico publicado en 2020

Mdivi-1 Protects Human W8B2+ Cardiac Stem Cells from Oxidative Stress and Simulated Ischemia-Reperfusion Injury.

artículo científico publicado en 2017

Meningococcal transferrin-binding proteins A and B show cooperation in their binding kinetics for human transferrin.

artículo científico publicado en 2005

Metabolism: Energy sensing through a sugar diphosphate

artículo científico publicado en 2017

Metformin and salicylate synergistically activate liver AMPK, inhibit lipogenesis and improve insulin sensitivity

artículo científico publicado en 2015

Neuropeptide Y1 receptor antagonism protects β-cells and improves glycemic control in type 2 diabetes

publication published on 07 December 2021

Phosphoproteomics reveals conserved exercise-stimulated signaling and AMPK regulation of store-operated calcium entry

artículo científico publicado en 2019

Quantitative proteomic analyses of dynamic signalling events in cortical neurons undergoing excitotoxic cell death

artículo científico publicado en 2019

Small molecule drug A-769662 and AMP synergistically activate naive AMPK independent of upstream kinase signaling.

artículo científico publicado en 2014

SnRK1 from Arabidopsis thaliana is an atypical AMPK.

artículo científico publicado en 2015

Structural Determinants for Small-Molecule Activation of Skeletal Muscle AMPK α2β2γ1 by the Glucose Importagog SC4.

artículo científico publicado en 2018

Structural basis of allosteric and synergistic activation of AMPK by furan-2-phosphonic derivative C2 binding

artículo científico publicado en 2016

Structure and function of AMP-activated protein kinase.

artículo científico publicado en 2009

The sweet side of AMPK signaling: regulation of GFAT1.

artículo científico publicado en 2017

Thienopyridone drugs are selective activators of AMP-activated protein kinase beta1-containing complexes.

artículo científico publicado en 2008

Transient Expression of AMPK Heterotrimer Complexes in Mammalian Cells

artículo científico publicado en 2018

Visualizing AMPK Drug Binding Sites Through Crystallization of Full-Length Phosphorylated α2β1γ1 Heterotrimer

artículo científico publicado en 2018

mTORC1 directly inhibits AMPK to promote cell proliferation under nutrient stress

scientific article published on 20 January 2020

β-Subunit myristoylation is the gatekeeper for initiating metabolic stress sensing by AMP-activated protein kinase (AMPK)

artículo científico publicado el 25 de octubre de 2010

β-subunit myristoylation functions as an energy sensor by modulating the dynamics of AMP-activated Protein Kinase

scientific article published on 21 December 2016