Lista de obras -

3-Nitrobenzanthrone and 3-aminobenzanthrone induce DNA damage and cell signalling in Hepa1c1c7 cells.

artículo científico publicado en 2009

3-Nitrofluoranthene (3-NF) but not 3-aminofluoranthene (3-AF) elicits apoptosis as well as programmed necrosis in Hepa1c1c7 cells.

artículo científico publicado en 2008

3-nitrofluoranthene (3-NF)-induced apoptosis and programmed necrosis.

artículo científico publicado en 2009

A role for caspase-8 and c-FLIPL in proliferation and cell-cycle progression of primary hepatocytes

scientific journal article

A role for lipid rafts in the protection afforded by docosahexaenoic acid against ethanol toxicity in primary rat hepatocytes.

artículo científico publicado en 2013

Acid sphingomyelinase deficiency protects from cisplatin-induced gastrointestinal damage.

artículo científico publicado en 2008

Acidic extracellular pH shifts colorectal cancer cell death from apoptosis to necrosis upon exposure to propionate and acetate, major end-products of the human probiotic propionibacteria.

artículo científico publicado en 2006

Acute cytotoxicity of the chemical carcinogen 2-acetylaminofluorene in cultured rat liver epithelial cells.

artículo científico publicado en 2002

AhR and Arnt differentially regulate NF-κB signaling and chemokine responses in human bronchial epithelial cells

artículo científico publicado en 2014

Akti-1/2, an allosteric inhibitor of Akt 1 and 2, efficiently inhibits CaMKIα activity and aryl hydrocarbon receptor pathway.

artículo científico publicado en 2010

Alternariol induces abnormal nuclear morphology and cell cycle arrest in murine RAW 264.7 macrophages.

artículo científico publicado en 2013

Apoptotic mitochondrial dysfunction induced by benzo(a)pyrene in liver epithelial cells: role of p53 and pHi changes.

artículo científico publicado en 2003

Aryl hydrocarbon receptor- and calcium-dependent induction of the chemokine CCL1 by the environmental contaminant benzo[a]pyrene.

artículo científico publicado en 2006

Aryl hydrocarbon receptor-independent up-regulation of intracellular calcium concentration by environmental polycyclic aromatic hydrocarbons in human endothelial HMEC-1 cells.

artículo científico publicado en 2012

Autophagy and senescence, stress responses induced by the DNA-damaging mycotoxin alternariol.

artículo científico publicado en 2014

Benzo(a)pyrene triggers desensitization of β2-adrenergic pathway

artículo científico publicado en 2017

Benzo[a]pyrene-induced nitric oxide production acts as a survival signal targeting mitochondrial membrane potential.

artículo científico publicado en 2015

Calcium signaling and β2-adrenergic receptors regulate 1-nitropyrene induced CXCL8 responses in BEAS-2B cells

artículo científico publicado en 2014

Characterization of intracellular pH regulation in the guinea-pig ventricular myocyte.

artículo científico publicado en 1999

Cisplatin cytotoxicity: DNA and plasma membrane targets.

scientific article published on January 2008

Cisplatin-Induced Apoptosis Involves Membrane Fluidification via Inhibition of NHE1 in Human Colon Cancer Cells

scientific article published on 01 August 2007

Cisplatin-induced CD95 redistribution into membrane lipid rafts of HT29 human colon cancer cells.

artículo científico publicado en 2004

Co-exposure to benzo[a]pyrene and ethanol induces a pathological progression of liver steatosis in vitro and in vivo.

artículo científico publicado en 2018

Combustion Particle-Induced Changes in Calcium Homeostasis: A Contributing Factor to Vascular Disease?

artículo científico publicado en 2019

Cooperative interaction of benzo[a]pyrene and ethanol on plasma membrane remodeling is responsible for enhanced oxidative stress and cell death in primary rat hepatocytes.

artículo científico publicado en 2014

Cytotoxicity of TRAIL/anticancer drug combinations in human normal cells

artículo científico publicado en 2006

Different mechanisms involved in apoptosis following exposure to benzo[a]pyrene in F258 and Hepa1c1c7 cells.

artículo científico publicado en 2007

Dioxin-mediated up-regulation of aryl hydrocarbon receptor target genes is dependent on the calcium/calmodulin/CaMKIalpha pathway.

artículo científico publicado en 2007

Disturbances in H+ dynamics during environmental carcinogenesis

artículo científico publicado en 2019

Effects of administration of the chemoprotective agent oltipraz on CYP1A and CYP2B in rat liver and rat hepatocytes in culture ⬇️

artículo científico publicado el 1 de julio de 1997

Effects of nitrated-polycyclic aromatic hydrocarbons and diesel exhaust particle extracts on cell signalling related to apoptosis: possible implications for their mutagenic and carcinogenic effects.

artículo científico publicado en 2006

Environmental carcinogenesis and pH homeostasis: Not only a matter of dysregulated metabolism.

artículo científico publicado en 2017

Evidence of selective activation of aryl hydrocarbon receptor nongenomic calcium signaling by pyrene

scientific article published on 22 September 2018

HCO 3 − -dependent alkalinizing transporter in adult rat ventricular myocytes: characterization and modulation ⬇️

artículo científico publicado el 1 de diciembre de 1997

Identification of Na+/H+ exchange as a new target for toxic polycyclic aromatic hydrocarbons.

artículo científico publicado en 2003

Identification of the couple GSK3α/c-Myc as a new regulator of hexokinase II in benzo[a]pyrene-induced apoptosis

scientific journal article

Induction of intracellular calcium concentration by environmental benzo(a)pyrene involves a β2-adrenergic receptor/adenylyl cyclase/Epac-1/inositol 1,4,5-trisphosphate pathway in endothelial cells.

artículo científico publicado en 2011

Intracellular sodium activity in papillary muscle from diabetic rat hearts ⬇️

artículo científico publicado el 1 de enero de 1991

Involvement of cyclic nucleotide- and calcium-regulated pathways in phenobarbital-induced cytochrome P-450 3A expression in mouse primary hepatocytes

artículo científico publicado en 1999

Kinetic analysis of the regulation of the Na+/H+ exchanger NHE-1 by osmotic shocks.

artículo científico publicado en 2008

Lipophilic Chemicals from Diesel Exhaust Particles Trigger Calcium Response in Human Endothelial Cells via Aryl Hydrocarbon Receptor Non-Genomic Signalling.

artículo científico publicado en 2018

Lipophilic components of diesel exhaust particles induce pro-inflammatory responses in human endothelial cells through AhR dependent pathway(s).

artículo científico publicado en 2018

Liver protection from apoptosis requires both blockage of initiator caspase activities and inhibition of ASK1/JNK pathway via glutathione S-transferase regulation.

artículo científico publicado en 2002

Mechanisms involved in lipid accumulation and apoptosis induced by 1-nitropyrene in Hepa1c1c7 cells.

artículo científico publicado en 2011

Mechanisms involved in the death of steatotic WIF-B9 hepatocytes co-exposed to benzo[a]pyrene and ethanol: a possible key role for xenobiotic metabolism and nitric oxide

scientific article published on 27 September 2018

Membrane Remodeling as a Key Player of the Hepatotoxicity Induced by Co-Exposure to Benzo[a]pyrene and Ethanol of Obese Zebrafish Larvae.

artículo científico publicado en 2018

Microalgal carotenoids and phytosterols regulate biochemical mechanisms involved in human health and disease prevention

artículo científico publicado en 2019

Moderate chronic ethanol consumption exerts beneficial effects on nonalcoholic fatty liver in mice fed a high-fat diet: possible role of higher formation of triglycerides enriched in monounsaturated fatty acids

scientific article published on 03 June 2019

Myristic acid increases dihydroceramide Δ4-desaturase 1 (DES1) activity in cultured rat hepatocytes

scientific article published on 03 December 2011

N-Myristoylation targets dihydroceramide Delta4-desaturase 1 to mitochondria: partial involvement in the apoptotic effect of myristic acid.

artículo científico publicado en 2009

NHE-1 relocation outside cholesterol-rich membrane microdomains is associated with its benzo[a]pyrene-related apoptotic function.

artículo científico publicado en 2012

Nongenomic effects of cisplatin: acute inhibition of mechanosensitive transporters and channels without actin remodeling.

artículo científico publicado en 2010

On some aspects of the thermodynamic of membrane recycling mediated by fluid phase endocytosis: evaluation of published data and perspectives.

artículo científico publicado en 2010

On the Role of the Difference in Surface Tensions Involved in the Allosteric Regulation of NHE-1 Induced by Low to Mild Osmotic Pressure, Membrane Tension and Lipid Asymmetry ⬇️

artículo científico publicado el 1 de mayo de 2012

Organic chemicals from diesel exhaust particles affects intracellular calcium, inflammation and β-adrenoceptors in endothelial cells

scientific article published on 29 November 2018

PAHs increase the production of extracellular vesicles both in vitro in endothelial cells and in vivo in urines from rats

scientific article published on 10 September 2019

Phagocytosis depends on TRPV2-mediated calcium influx and requires TRPV2 in lipids rafts: alteration in macrophages from patients with cystic fibrosis.

artículo científico publicado en 2018

Physical and chemical modulation of lipid rafts by a dietary n-3 polyunsaturated fatty acid increases ethanol-induced oxidative stress

artículo científico publicado en 2011

Polycyclic aromatic hydrocarbons can trigger hepatocyte release of extracellular vesicles by various mechanisms of action depending on their affinity for the aryl hydrocarbon receptor

scientific article published on 31 July 2019

Possible Involvement of Mitochondrial Dysfunction and Oxidative Stress in a Cellular Model of NAFLD Progression Induced by Benzo[a]pyrene/Ethanol CoExposure.

artículo científico publicado en 2018

Protective action of n-3 fatty acids on benzo[a]pyrene-induced apoptosis through the plasma membrane remodeling-dependent NHE1 pathway.

artículo científico publicado en 2013

RNAi-Based Screening Identifies Kinases Interfering with Dioxin-Mediated Up-Regulation of CYP1A1 Activity ⬇️

artículo científico publicado el 29 de marzo de 2011

Regulation of Na+/H+ exchanger 1 allosteric balance by its localization in cholesterol- and caveolin-rich membrane microdomains.

artículo científico publicado en 2008

Role for membrane remodeling in cell death: implication for health and disease.

artículo científico

Role for mitogen-activated protein kinases in phenobarbital-induced expression of cytochrome P450 2B in primary cultures of rat hepatocytes.

artículo científico publicado en 2005

Role for the ATPase inhibitory factor 1 in the environmental carcinogen-induced Warburg phenotype.

artículo científico publicado en 2017

Role of bicarbonate in pH recovery from intracellular acidosis in the guinea-pig ventricular myocyte ⬇️

artículo científico publicado el 1 de diciembre de 1992

Role of intracellular glutathione in cell sensitivity to the apoptosis induced by tumor necrosis factor {alpha}-related apoptosis-inducing ligand/anticancer drug combinations.

artículo científico publicado en 2005

Signalling pathways involved in 1-nitropyrene (1-NP)-induced and 3-nitrofluoranthene (3-NF)-induced cell death in Hepa1c1c7 cells.

artículo científico publicado en 2009

The cleaved FAS ligand activates the Na(+)/H(+) exchanger NHE1 through Akt/ROCK1 to stimulate cell motility

artículo científico publicado en 2016

The environmental carcinogen benzo[a]pyrene induces a Warburg-like metabolic reprogramming dependent on NHE1 and associated with cell survival.

artículo científico publicado en 2016

Toxic effects of tacrine on primary hepatocytes and liver epithelial cells in culture

scientific article published on 01 October 1998

Zebrafish larva as a reliable model for in vivo assessment of membrane remodeling involvement in the hepatotoxicity of chemical agents.

artículo científico publicado en 2016

Lista de obras de

3-Nitrobenzanthrone and 3-aminobenzanthrone induce DNA damage and cell signalling in Hepa1c1c7 cells.

3-Nitrofluoranthene (3-NF) but not 3-aminofluoranthene (3-AF) elicits apoptosis as well as programmed necrosis in Hepa1c1c7 cells.

3-nitrofluoranthene (3-NF)-induced apoptosis and programmed necrosis.

A role for caspase-8 and c-FLIPL in proliferation and cell-cycle progression of primary hepatocytes

A role for lipid rafts in the protection afforded by docosahexaenoic acid against ethanol toxicity in primary rat hepatocytes.

Acid sphingomyelinase deficiency protects from cisplatin-induced gastrointestinal damage.

Acidic extracellular pH shifts colorectal cancer cell death from apoptosis to necrosis upon exposure to propionate and acetate, major end-products of the human probiotic propionibacteria.

Acute cytotoxicity of the chemical carcinogen 2-acetylaminofluorene in cultured rat liver epithelial cells.

AhR and Arnt differentially regulate NF-κB signaling and chemokine responses in human bronchial epithelial cells

Akti-1/2, an allosteric inhibitor of Akt 1 and 2, efficiently inhibits CaMKIα activity and aryl hydrocarbon receptor pathway.

Alternariol induces abnormal nuclear morphology and cell cycle arrest in murine RAW 264.7 macrophages.

Apoptotic mitochondrial dysfunction induced by benzo(a)pyrene in liver epithelial cells: role of p53 and pHi changes.

Aryl hydrocarbon receptor- and calcium-dependent induction of the chemokine CCL1 by the environmental contaminant benzo[a]pyrene.

Aryl hydrocarbon receptor-independent up-regulation of intracellular calcium concentration by environmental polycyclic aromatic hydrocarbons in human endothelial HMEC-1 cells.

Autophagy and senescence, stress responses induced by the DNA-damaging mycotoxin alternariol.

Benzo(a)pyrene triggers desensitization of β2-adrenergic pathway

Benzo[a]pyrene-induced nitric oxide production acts as a survival signal targeting mitochondrial membrane potential.

Calcium signaling and β2-adrenergic receptors regulate 1-nitropyrene induced CXCL8 responses in BEAS-2B cells

Characterization of intracellular pH regulation in the guinea-pig ventricular myocyte.

Cisplatin cytotoxicity: DNA and plasma membrane targets.

Cisplatin-Induced Apoptosis Involves Membrane Fluidification via Inhibition of NHE1 in Human Colon Cancer Cells

Cisplatin-induced CD95 redistribution into membrane lipid rafts of HT29 human colon cancer cells.

Co-exposure to benzo[a]pyrene and ethanol induces a pathological progression of liver steatosis in vitro and in vivo.

Combustion Particle-Induced Changes in Calcium Homeostasis: A Contributing Factor to Vascular Disease?

Cooperative interaction of benzo[a]pyrene and ethanol on plasma membrane remodeling is responsible for enhanced oxidative stress and cell death in primary rat hepatocytes.

Cytotoxicity of TRAIL/anticancer drug combinations in human normal cells

Different mechanisms involved in apoptosis following exposure to benzo[a]pyrene in F258 and Hepa1c1c7 cells.

Dioxin-mediated up-regulation of aryl hydrocarbon receptor target genes is dependent on the calcium/calmodulin/CaMKIalpha pathway.

Disturbances in H+ dynamics during environmental carcinogenesis

Effects of administration of the chemoprotective agent oltipraz on CYP1A and CYP2B in rat liver and rat hepatocytes in culture ⬇️

Effects of nitrated-polycyclic aromatic hydrocarbons and diesel exhaust particle extracts on cell signalling related to apoptosis: possible implications for their mutagenic and carcinogenic effects.

Environmental carcinogenesis and pH homeostasis: Not only a matter of dysregulated metabolism.

Evidence of selective activation of aryl hydrocarbon receptor nongenomic calcium signaling by pyrene

HCO 3 − -dependent alkalinizing transporter in adult rat ventricular myocytes: characterization and modulation ⬇️

Identification of Na+/H+ exchange as a new target for toxic polycyclic aromatic hydrocarbons.

Identification of the couple GSK3α/c-Myc as a new regulator of hexokinase II in benzo[a]pyrene-induced apoptosis

Induction of intracellular calcium concentration by environmental benzo(a)pyrene involves a β2-adrenergic receptor/adenylyl cyclase/Epac-1/inositol 1,4,5-trisphosphate pathway in endothelial cells.

Intracellular sodium activity in papillary muscle from diabetic rat hearts ⬇️

Involvement of cyclic nucleotide- and calcium-regulated pathways in phenobarbital-induced cytochrome P-450 3A expression in mouse primary hepatocytes

Kinetic analysis of the regulation of the Na+/H+ exchanger NHE-1 by osmotic shocks.

Lipophilic Chemicals from Diesel Exhaust Particles Trigger Calcium Response in Human Endothelial Cells via Aryl Hydrocarbon Receptor Non-Genomic Signalling.

Lipophilic components of diesel exhaust particles induce pro-inflammatory responses in human endothelial cells through AhR dependent pathway(s).

Liver protection from apoptosis requires both blockage of initiator caspase activities and inhibition of ASK1/JNK pathway via glutathione S-transferase regulation.

Mechanisms involved in lipid accumulation and apoptosis induced by 1-nitropyrene in Hepa1c1c7 cells.

Mechanisms involved in the death of steatotic WIF-B9 hepatocytes co-exposed to benzo[a]pyrene and ethanol: a possible key role for xenobiotic metabolism and nitric oxide

Membrane Remodeling as a Key Player of the Hepatotoxicity Induced by Co-Exposure to Benzo[a]pyrene and Ethanol of Obese Zebrafish Larvae.

Microalgal carotenoids and phytosterols regulate biochemical mechanisms involved in human health and disease prevention

Moderate chronic ethanol consumption exerts beneficial effects on nonalcoholic fatty liver in mice fed a high-fat diet: possible role of higher formation of triglycerides enriched in monounsaturated fatty acids

Myristic acid increases dihydroceramide Δ4-desaturase 1 (DES1) activity in cultured rat hepatocytes

N-Myristoylation targets dihydroceramide Delta4-desaturase 1 to mitochondria: partial involvement in the apoptotic effect of myristic acid.

NHE-1 relocation outside cholesterol-rich membrane microdomains is associated with its benzo[a]pyrene-related apoptotic function.

Nongenomic effects of cisplatin: acute inhibition of mechanosensitive transporters and channels without actin remodeling.

On some aspects of the thermodynamic of membrane recycling mediated by fluid phase endocytosis: evaluation of published data and perspectives.

On the Role of the Difference in Surface Tensions Involved in the Allosteric Regulation of NHE-1 Induced by Low to Mild Osmotic Pressure, Membrane Tension and Lipid Asymmetry ⬇️

Organic chemicals from diesel exhaust particles affects intracellular calcium, inflammation and β-adrenoceptors in endothelial cells

PAHs increase the production of extracellular vesicles both in vitro in endothelial cells and in vivo in urines from rats

Phagocytosis depends on TRPV2-mediated calcium influx and requires TRPV2 in lipids rafts: alteration in macrophages from patients with cystic fibrosis.

Physical and chemical modulation of lipid rafts by a dietary n-3 polyunsaturated fatty acid increases ethanol-induced oxidative stress

Polycyclic aromatic hydrocarbons can trigger hepatocyte release of extracellular vesicles by various mechanisms of action depending on their affinity for the aryl hydrocarbon receptor

Possible Involvement of Mitochondrial Dysfunction and Oxidative Stress in a Cellular Model of NAFLD Progression Induced by Benzo[a]pyrene/Ethanol CoExposure.

Protective action of n-3 fatty acids on benzo[a]pyrene-induced apoptosis through the plasma membrane remodeling-dependent NHE1 pathway.

RNAi-Based Screening Identifies Kinases Interfering with Dioxin-Mediated Up-Regulation of CYP1A1 Activity ⬇️

Regulation of Na+/H+ exchanger 1 allosteric balance by its localization in cholesterol- and caveolin-rich membrane microdomains.

Role for membrane remodeling in cell death: implication for health and disease.

Role for mitogen-activated protein kinases in phenobarbital-induced expression of cytochrome P450 2B in primary cultures of rat hepatocytes.

Role for the ATPase inhibitory factor 1 in the environmental carcinogen-induced Warburg phenotype.

Role of bicarbonate in pH recovery from intracellular acidosis in the guinea-pig ventricular myocyte ⬇️

Role of intracellular glutathione in cell sensitivity to the apoptosis induced by tumor necrosis factor {alpha}-related apoptosis-inducing ligand/anticancer drug combinations.

Signalling pathways involved in 1-nitropyrene (1-NP)-induced and 3-nitrofluoranthene (3-NF)-induced cell death in Hepa1c1c7 cells.

The cleaved FAS ligand activates the Na(+)/H(+) exchanger NHE1 through Akt/ROCK1 to stimulate cell motility

The environmental carcinogen benzo[a]pyrene induces a Warburg-like metabolic reprogramming dependent on NHE1 and associated with cell survival.

Toxic effects of tacrine on primary hepatocytes and liver epithelial cells in culture

Zebrafish larva as a reliable model for in vivo assessment of membrane remodeling involvement in the hepatotoxicity of chemical agents.