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A New Regulatory Protein of Catecholamine Synthesizing-Enzyme Expression

artículo científico publicado el 1 de enero de 1998

A novel diol-derivative of chalcone produced by bioconversion, 3-(2,3-dihydroxyphenyl)-1-phenylpropan-1-one, activates PKA/MEK/ERK signaling and antagonizes Abeta-inhibition of the cascade in cultured rat CNS neurons.

artículo científico publicado en 2008

A novel mechanism of depression: role for connexins.

artículo científico publicado en 2018

A novel protein containing Cdc10/SWI6 motifs regulates expression of mRNA encoding catecholamine biosynthesizing enzymes.

artículo científico publicado en 1998

Acidosis-induced protein tyrosine phosphorylation depends on Ca2+ influx via voltage-dependent Ca2+ channels in SHR aorta.

artículo científico publicado en 2004

Beneficial effects of Ajuga decumbens on osteoporosis and arthritis.

artículo científico publicado en 2008

Bioactive ent-clerodane diterpenoids from the aerial parts of Baccharis gaudichaudiana

scientific article published on 01 February 2006

Ca2+ channel activating action of maitotoxin in cultured brainstem neurons.

artículo científico publicado en 2006

Clerodane diterpenoids and flavonoids with NGF-potentiating activity from the aerial parts of Baccharis gaudichaudiana

scientific article published on 01 October 2007

Development and migration of Purkinje cells in the mouse cerebellar primordium

artículo científico publicado el 1 de enero de 1991

Dopamine or biopterin deficiency potentiates phosphorylation at (40)Ser and ubiquitination of tyrosine hydroxylase to be degraded by the ubiquitin proteasome system

artículo científico publicado en 2015

Dual effects of nobiletin, a citrus polymethoxy flavone, on catecholamine secretion in cultured bovine adrenal medullary cells.

artículo científico publicado en 2010

Ephedorae herba decreases lipopolysaccharide-induced cyclooxgenase-2 protein expression and NF-kappaB-dependent transcription in C6 rat glioma cells.

artículo científico publicado en 2005

Extracellular α-synuclein enters dopaminergic cells by modulating flotillin-1-assisted dopamine transporter endocytosis

scientific article published on 18 June 2019

Fermented Citrus reticulata (ponkan) fruit squeezed draff that contains a large amount of 4'-demethylnobiletin prevents MK801-induced memory impairment.

artículo científico publicado en 2017

Four new myrsinol diterpenes from Euphorbia prolifera.

artículo científico publicado en 2012

Garcinone B reduces prostaglandin E2 release and NF-kappaB-mediated transcription in C6 rat glioma cells.

artículo científico publicado en 2005

Ginsenoside Rg1 alleviates corticosterone-induced dysfunction of gap junctions in astrocytes.

artículo científico publicado en 2017

Heterogeneity of the ciliary epithelium of the rat eye as revealed by spot 35 protein (a Purkinje cell specific protein)-like immunoreactivity

artículo científico publicado el 1 de enero de 1988

High-performance liquid chromatography with photodiode array detection for determination of nobiletin content in the brain and serum of mice administrated the natural compound

artículo científico publicado en 2011

IC101 induces apoptosis by Akt dephosphorylation via an inhibition of heat shock protein 90-ATP binding activity accompanied by preventing the interaction with Akt in L1210 cells.

artículo científico publicado en 2004

Imidacloprid, a neonicotinoid insecticide, facilitates tyrosine hydroxylase transcription and phenylethanolamine N-methyltransferase mRNA expression to enhance catecholamine synthesis and its nicotine-evoked elevation in PC12D cells

artículo científico publicado en 2017

Iridoids and sesquiterpenoids with NGF-potentiating activity from the rhizomes and roots of Valeriana fauriei

scientific article published on 01 January 2006

Isolation and immunohistochemical localization of a cerebellar protein

artículo científico publicado el 6 de abril de 1984

Metronomic scheduling of a cyclic hexapeptide Ra-VII for anti-angiogenesis, tumor vessel maturation and anti-tumor activity.

artículo científico publicado en 2006

Nardosinone enhances nerve growth factor-induced neurite outgrowth in a mitogen-activated protein kinase- and protein kinase C-dependent manner in PC12D cells

artículo científico publicado en 2003

Nardosinone, the first enhancer of neurite outgrowth-promoting activity of staurosporine and dibutyryl cyclic AMP in PC12D cells

artículo científico publicado el 12 de noviembre de 2003

Neurobehavioral effects of tetrabromobisphenol A, a brominated flame retardant, in mice.

artículo científico publicado en 2009

Neuroprotective Kaurane Diterpenes from Fritillaria ebeiensis.

artículo científico publicado en 2011

Nobiletin and its related flavonoids with CRE-dependent transcription-stimulating and neuritegenic activities.

artículo científico publicado en 2005

Nobiletin induces inhibitions of Ras activity and mitogen-activated protein kinase kinase/extracellular signal-regulated kinase signaling to suppress cell proliferation in C6 rat glioma cells.

artículo científico publicado en 2013

Nobiletin restoring beta-amyloid-impaired CREB phosphorylation rescues memory deterioration in Alzheimer's disease model rats.

artículo científico publicado en 2006

Nobiletin, a citrus flavonoid that improves memory impairment, rescues bulbectomy-induced cholinergic neurodegeneration in mice.

artículo científico publicado en 2007

Nobiletin, a citrus flavonoid with neurotrophic action, augments protein kinase A-mediated phosphorylation of the AMPA receptor subunit, GluR1, and the postsynaptic receptor response to glutamate in murine hippocampus.

artículo científico publicado en 2007

Nobiletin, a citrus flavonoid, improves memory impairment and Abeta pathology in a transgenic mouse model of Alzheimer's disease.

artículo científico publicado en 2008

Nobiletin-rich Citrus reticulata peels, a kampo medicine for Alzheimer's disease: a case series.

artículo científico publicado en 2013

Potent activity of nobiletin-rich Citrus reticulata peel extract to facilitate cAMP/PKA/ERK/CREB signaling associated with learning and memory in cultured hippocampal neurons: identification of the substances responsible for the pharmacological acti

artículo científico publicado en 2013

Preventive action of nobiletin, a constituent of AURANTII NOBILIS PERICARPIUM with anti-dementia activity, against amyloid-beta peptide-induced neurotoxicity expression and memory impairment

artículo científico publicado en 2010

Production and secretion of nerve growth factor by clonal striated muscle cell line, G8-1

artículo científico publicado el 1 de septiembre de 1992

Regulation of nerve growth factor and nerve growth factor receptor production by NMDA in C6 glioma cells

artículo científico publicado el 1 de junio de 1992

Repeated treatment with nicotine induces phosphorylation of NMDA receptor NR2B subunit in the brain regions involved in behavioral sensitization.

artículo científico publicado en 2012

SLC10A4 is a protease-activated transporter that transports bile acids.

artículo científico publicado en 2013

Stimulated tyrosine phosphorylation of phosphatidylinositol 3-kinase causes acidic pH-induced contraction in spontaneously hypertensive rat aorta.

artículo científico publicado en 2002

Three new iridoids from the roots of Valeriana jatamansi

artículo científico publicado en 2012

Three-membered ring sesquiterpenoids with NGF-potentiating activity from the roots of Valeriana fauriei

scientific article published on 01 March 2006

Two Distinct Mechanisms for Actin Capping Protein Regulation—Steric and Allosteric Inhibition

artículo científico publicado en 2010

Two steroidal saponins from Camassia cusickii induce L1210 cell death through the apoptotic mechanism.

artículo científico publicado en 2001

[Elucidation of mechanism underlying amyloid-beta peptide aggregation and its neurotoxicity expression and inhibition of these molecular processes by beneficial synthetic and natural compounds with low-molecular weights-new approaches to fundamental

artículo científico publicado en 2010

[Pharmacological superiority of nobiletin-rich Citrus reticulata peel, a multicomponent drug, over nobiletin alone regarding anti-dementia action].

artículo científico publicado en 2015