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10 Factors involved in leukaemogenesis and haemopoiesis

artículo científico publicado el 1 de septiembre de 1997

1010 - CHARACTERIZING HOXA-EXPRESSING ENDOTHELIAL AND HAEMATOPOIETIC POPULATIONS DERIVED FROM HUMAN PLURIPOTENT STEM CELLS

scholarly article

3176 – MULTIPOTENT RAG1+ PROGENITORS EMERGE DIRECTLY FROM HEMOGENIC ENDOTHELIUM IN HUMAN PSC DERIVED HEMOPOIETIC ORGANOIDS

artículo científico publicado en 2019

A Cas9 Variant for Efficient Generation of Indel-Free Knockin or Gene-Corrected Human Pluripotent Stem Cells

artículo científico publicado en 2016

A Pro-Endocrine Pancreatic Islet Transcriptional Program Established During Development Is Retained in Human Gallbladder Epithelial Cells

artículo científico publicado en 2022

A method for genetic modification of human embryonic stem cells using electroporation

artículo científico publicado en 2007

A mouse carrying the green fluorescent protein gene targeted to the Pdx1 locus facilitates the study of pancreas development and function.

artículo científico publicado en 2006

A protocol describing the use of a recombinant protein-based, animal product-free medium (APEL) for human embryonic stem cell differentiation as spin embryoid bodies

artículo científico publicado en 2008

A protocol for removal of antibiotic resistance cassettes from human embryonic stem cells genetically modified by homologous recombination or transgenesis

scientific article published on 01 January 2008

A targeted NKX2.1 human embryonic stem cell reporter line enables identification of human basal forebrain derivatives.

artículo científico publicado en 2011

ALPK3-deficient cardiomyocytes generated from patient-derived induced pluripotent stem cells and mutant human embryonic stem cells display abnormal calcium handling and establish that ALPK3 deficiency underlies familial cardiomyopathy.

artículo científico publicado en 2016

APELIN promotes hematopoiesis from human embryonic stem cells

scientific article published on 18 May 2012

Aberrant hematopoiesis in mice with inactivation of the gene encoding SOCS-1

scientific article published on 01 June 1999

An INSULIN-GFP/GLUCAGON-mCherry reporter line for the study of human pancreatic endocrine cell development

artículo científico

Analysis of mitochondrial function and localisation during human embryonic stem cell differentiation in vitro.

artículo científico publicado en 2012

Apoptosis and beta-cell destruction in pancreatic islets of NOD mice with spontaneous and cyclophosphamide-accelerated diabetes

artículo científico publicado en 1998

Blood cells form from phenotypically distinct precursors during human blast colony differentiation

artículo científico publicado en 2015

Brachyury and related Tbx proteins interact with the Mixl1 homeodomain protein and negatively regulate Mixl1 transcriptional activity

artículo científico publicado en 2011

Building better beta cells

scientific article published on 01 April 2008

CD13 and ROR2 Permit Isolation of Highly Enriched Cardiac Mesoderm from Differentiating Human Embryonic Stem Cells

artículo científico publicado en 2016

CD90 Marks a Mesenchymal Program in Human Thymic Epithelial Cells <i>In Vitro</i> and <i>In Vivo</i>

artículo científico publicado en 2022

CRISPR/Cas9 gene editing of a SOX9 reporter human iPSC line to produce two TRPV4 patient heterozygous missense mutant iPSC lines, MCRIi001-A-3 (TRPV4 p.F273L) and MCRIi001-A-4 (TRPV4 p.P799L)

scientific article published on 03 August 2020

Characterization of hematopoietic progenitor cells that express the transcription factor SCL, using a lacZ "knock-in" strategy

artículo científico publicado en 1998

Defined substrates for pluripotent stem cells: are we there yet?

artículo científico publicado el 1 de diciembre de 2010

Derivation of endothelial cells from human embryonic stem cells in fully defined medium enables identification of lysophosphatidic acid and platelet activating factor as regulators of eNOS localization

artículo científico publicado en 2012

Derivation of insulin-producing beta-cells from human pluripotent stem cells

artículo científico publicado en 2014

Differentiating embryonic stem cells pass through 'temporal windows' that mark responsiveness to exogenous and paracrine mesendoderm inducing signals

artículo científico publicado en 2010

Differentiation of human embryonic stem cells and induced pluripotent stem cells to cardiomyocytes: a methods overview

artículo científico publicado en 2012

Differentiation of human embryonic stem cells in serum-free medium reveals distinct roles for bone morphogenetic protein 4, vascular endothelial growth factor, stem cell factor, and fibroblast growth factor 2 in hematopoiesis

artículo científico publicado en 2007

Differentiation of human embryonic stem cells to HOXA+ hemogenic vasculature that resembles the aorta-gonad-mesonephros.

artículo científico publicado en 2016

Directed differentiation and functional maturation of cortical interneurons from human embryonic stem cells

artículo científico publicado en 2013

Directed differentiation of human embryonic stem cells as spin embryoid bodies and a description of the hematopoietic blast colony forming assay

artículo científico publicado en 2008

Directing human embryonic stem cell differentiation towards a renal lineage generates a self-organizing kidney

artículo científico publicado en 2013

ESTOOLS, a project funded by the European Commission(FP6), gathers expertise on human embryonic stem cells in 10 countries of the European Research Area

artículo científico publicado en 2009

Efficient Cre-mediated deletion in cardiac progenitor cells conferred by a 3'UTR-ires-Cre allele of the homeobox gene Nkx2-5.

artículo científico publicado en 2002

Efficient endoderm induction from human pluripotent stem cells by logically directing signals controlling lineage bifurcations.

artículo científico publicado en 2014

Efficient generation of NKX6-1+ pancreatic progenitors from multiple human pluripotent stem cell lines

artículo científico publicado en 2015

Efficient generation of adipocytes in a dish

artículo científico publicado el 2 de febrero de 2012

Efficiently Specified Ventral Midbrain Dopamine Neurons from Human Pluripotent Stem Cells Under Xeno-Free Conditions Restore Motor Deficits in Parkinsonian Rodents.

artículo científico publicado en 2016

Endocrine cells develop within pancreatic bud-like structures derived from mouse ES cells differentiated in response to BMP4 and retinoic acid

artículo científico publicado en 2007

Enforced Expression of HOXB4 in Human Embryonic Stem Cells Enhances the Production of Hematopoietic Progenitors but Has No Effect on the Maturation of Red Blood Cells.

scientific article published on 28 June 2016

Enforced expression of Mixl1 during mouse ES cell differentiation suppresses hematopoietic mesoderm and promotes endoderm formation

scientific journal article

Engineered human pluripotent-stem-cell-derived intestinal tissues with a functional enteric nervous system

artículo científico publicado en 2016

ErythRED, a hESC line enabling identification of erythroid cells

artículo científico publicado en 2009

Expansion of human embryonic stem cells in vitro

artículo científico publicado en 2008

Expression from a betageo gene trap in the Slain1 gene locus is predominantly associated with the developing nervous system.

artículo científico publicado en 2010

Expression of BCR – ABL in M1 myeloid leukemia cells induces differentiation without arresting proliferation

scientific article published on 01 January 1999

Expression of RUNX1-ETO Rapidly Alters the Chromatin Landscape and Growth of Early Human Myeloid Precursor Cells

artículo científico publicado en 2020

Expression pattern of the stem cell leukaemia gene in the CNS of the embryonic and adult mouse.

artículo científico publicado en 2003

FOXN1 (GFP/w) reporter hESCs enable identification of integrin-β4, HLA-DR, and EpCAM as markers of human PSC-derived FOXN1(+) thymic epithelial progenitors.

artículo científico publicado en 2014

Five years of Stem Cell Research — Reflections on progress in the field

artículo científico publicado el 1 de noviembre de 2012

Forced aggregation of defined numbers of human embryonic stem cells into embryoid bodies fosters robust, reproducible hematopoietic differentiation.

artículo científico publicado en 2005

Fourier transform infrared microspectroscopy identifies early lineage commitment in differentiating human embryonic stem cells

artículo científico publicado en 2009

Fourier transform infrared microspectroscopy reveals that tissue culture conditions affect the macromolecular phenotype of human embryonic stem cells

artículo científico publicado en 2013

Fourier transform infrared microspectroscopy reveals unique phenotypes for human embryonic and induced pluripotent stem cell lines and their progeny.

artículo científico publicado en 2013

Functional maturation of hPSC-derived forebrain interneurons requires an extended timeline and mimics human neural development.

artículo científico publicado en 2013

Fusion of Regionally Specified hPSC-Derived Organoids Models Human Brain Development and Interneuron Migration

artículo científico publicado en 2017

GAPTrap: A Simple Expression System for Pluripotent Stem Cells and Their Derivatives

artículo científico publicado en 2016

Generating GABAergic cerebral cortical interneurons from mouse and human embryonic stem cells.

artículo científico

Generation of RAB39B knockout isogenic human embryonic stem cell lines to model RAB39B-mediated Parkinson's disease.

artículo científico publicado en 2018

Generation of a SOX9-tdTomato reporter human iPSC line, MCRIi001-A-2, using CRISPR/Cas9 editing

artículo científico publicado en 2019

Generation of a heterozygous COL1A1 (c.3969_3970insT) osteogenesis imperfecta mutation human iPSC line, MCRIi001-A-1, using CRISPR/Cas9 editing

scientific article published on 23 April 2019

Generation of a heterozygous COL2A1 (p.R989C) spondyloepiphyseal dysplasia congenita mutation iPSC line, MCRIi001-B, using CRISPR/Cas9 gene editing

artículo científico publicado en 2020

Generation of human embryonic stem cell reporter knock-in lines by homologous recombination

artículo científico publicado en 2009

Generation of human female reproductive tract epithelium from human embryonic stem cells.

artículo científico publicado en 2011

Generation of iPSC lines from peripheral blood mononuclear cells from 5 healthy adults

scientific article published on 27 December 2018

Generation of megakaryocytic progenitors from human embryonic stem cells in a feeder- and serum-free medium.

artículo científico publicado en 2013

Human acquired naevi are clonal

artículo científico publicado en 1998

Human chondrogenic paraxial mesoderm, directed specification and prospective isolation from pluripotent stem cells

artículo científico publicado en 2012

Human definitive haemogenic endothelium and arterial vascular endothelium represent distinct lineages

artículo científico publicado en 2015

Human embryonic stem cell derived mesenchymal progenitors express cardiac markers but do not form contractile cardiomyocytes.

artículo científico publicado en 2013

Human haematopoietic stem cell development: from the embryo to the dish

artículo científico publicado en 2017

Human yolk sac-like haematopoiesis generates RUNX1- and GFI1/1B-dependent blood and SOX17-positive endothelium

artículo científico publicado en 2020

In the absence of apoptosis, myeloid cells arrest when deprived of growth factor, but remain viable by consuming extracellular glucose

artículo científico publicado en 2019

In this issue...

artículo científico publicado en 2007

Inaugural issue of Stem Cell Research

artículo científico publicado en 2007

Induced pluripotent stem cell macrophages present antigen to proinsulin-specific T cell receptors from donor-matched islet-infiltrating T cells in type 1 diabetes

artículo científico publicado en 2019

Inhibition of DYRK1A disrupts neural lineage specification in human pluripotent stem cells

artículo científico publicado en 2017

Integrin αvβ5 heterodimer is a specific marker of human pancreatic beta cells

artículo científico publicado en 2021

Isolation of human lymphatic endothelial cells by multi-parameter fluorescence-activated cell sorting

artículo científico publicado en 2015

Liver degeneration and lymphoid deficiencies in mice lacking suppressor of cytokine signaling-1.

artículo científico publicado en 1998

Long-Term Maintenance of Human Pluripotent Stem Cells on cRGDfK-Presenting Synthetic Surfaces.

artículo científico publicado en 2018

Magnetic Resonance Imaging of Iron Oxide-Labeled Human Embryonic Stem Cell-Derived Cardiac Progenitors

artículo científico publicado en 2015

Mapping human haematopoietic stem cells from haemogenic endothelium to birth

artículo científico publicado en 2022

Microbioreactor arrays for full factorial screening of exogenous and paracrine factors in human embryonic stem cell differentiation.

artículo científico publicado en 2012

Mimicry of embryonic circulation enhances the hoxa hemogenic niche and human blood development

scientific article published in 2022

Mixl1 and oct4 proteins are transiently co-expressed in differentiating mouse and human embryonic stem cells.

artículo científico publicado en 2005

Mixl1 is required for axial mesendoderm morphogenesis and patterning in the murine embryo

scientific journal article

Multipotent RAG1+ progenitors emerge directly from haemogenic endothelium in human pluripotent stem cell-derived haematopoietic organoids

artículo científico publicado en 2020

NKX2-5 regulates human cardiomyogenesis via a HEY2 dependent transcriptional network

artículo científico publicado en 2018

NKX2-5(eGFP/w) hESCs for isolation of human cardiac progenitors and cardiomyocytes.

artículo científico publicado en 2011

On the streets of San Francisco: highlights from the ISSCR Annual Meeting 2010.

artículo científico publicado en 2010

One final word…

artículo científico publicado en 2014

Overcoming Monocarboxylate Transporter 8 (MCT8)-Deficiency to Promote Human Oligodendrocyte Differentiation and Myelination

artículo científico publicado en 2017

PGC-1α and reactive oxygen species regulate human embryonic stem cell-derived cardiomyocyte function.

artículo científico publicado en 2013

Pancreas differentiation of mouse ES cells

artículo científico publicado en 2007

Pancreatic differentiation from pluripotent stem cells: tweaking the system.

artículo científico publicado en 2009

Pdgfrα and Flk1 are direct target genes of Mixl1 in differentiating embryonic stem cells.

artículo científico publicado en 2011

Productive Infection of Human Embryonic Stem Cell-Derived NKX2.1+ Respiratory Progenitors with Human Rhinovirus.

artículo científico publicado en 2015

RUNX1 AND GROUP F SOX GENES ARE REQUIRED AT DISTINCT STAGES FOR HUMAN HAEMATOPOIETIC DEVELOPMENT

scholarly article

RUNX1-ETO RAPIDLY REPROGRAMS THE EPIGENETIC LANDSCAPE IN HUMAN EMBRYONIC DEFINITIVE HAEMATOPOIETIC PROGENITORS

scholarly article

RUNX1c Regulates Hematopoietic Differentiation of Human Pluripotent Stem Cells Possibly in Cooperation with Proinflammatory Signaling.

artículo científico publicado en 2017

Regulatory networks specifying cortical interneurons from human embryonic stem cells reveal roles for CHD2 in interneuron development

artículo científico publicado en 2017

Reshaping pluripotent stem cells

artículo científico publicado en 2009

Retinoic acid induces Pdx1-positive endoderm in differentiating mouse embryonic stem cells

artículo científico publicado en 2004

SIRPA is a specific cell-surface marker for isolating cardiomyocytes derived from human pluripotent stem cells.

artículo científico publicado en 2011

SIRPA, VCAM1 and CD34 identify discrete lineages during early human cardiovascular development.

artículo científico publicado en 2014

Simultaneous Reprogramming and Gene Correction of Patient Fibroblasts

artículo científico publicado en 2015

Spatio-temporal re-organization of replication foci accompanies replication domain consolidation during human pluripotent stem cell lineage specification.

artículo científico publicado en 2016

Stage-specific signaling through TGFβ family members and WNT regulates patterning and pancreatic specification of human pluripotent stem cells.

artículo científico publicado en 2011

Stem Cell Research. In this issue.

artículo científico publicado en 2008

Stem cells in biology, tissue engineering and medicine: the leading edge keeps moving.

artículo científico publicado en 2007

THE ROLE OF SHEAR STRESS IN THE GENERATION OF DEFINITIVE HAEMATOPOIETIC LINEAGES AND ARTERIAL VASCULATURE FROM HUMAN PLURIPOTENT STEM CELLS AT THE SINGLE-CELL LEVEL

scholarly article

THE ROLE OF VENTX HOMEOBOX GENE DURING HUMAN HAEMATOPOIETIC DEVELOPMENT

scholarly article

Targeting a GFP reporter gene to the MIXL1 locus of human embryonic stem cells identifies human primitive streak-like cells and enables isolation of primitive hematopoietic precursors.

artículo científico publicado en 2007

Temporal restriction of pancreatic branching competence during embryogenesis is mirrored in differentiating embryonic stem cells

artículo científico publicado en 2011

The Mix family of homeobox genes--key regulators of mesendoderm formation during vertebrate development.

artículo científico publicado en 2012

The characterisation of pluripotent and multipotent stem cells using Fourier transform infrared microspectroscopy.

scientific article published on 26 August 2013

The critical regulator of embryonic hematopoiesis, SCL, is vital in the adult for megakaryopoiesis, erythropoiesis, and lineage choice in CFU-S12

scientific journal article

The hESC line Envy expresses high levels of GFP in all differentiated progeny.

artículo científico publicado en 2005

The level of the tissue‐specific factor GATA‐1 affects the cell‐cycle machinery

artículo científico publicado el 1 de febrero de 1997

The primitive streak gene Mixl1 is required for efficient haematopoiesis and BMP4-induced ventral mesoderm patterning in differentiating ES cells

artículo científico publicado en 2005

The role of cardiac transcription factor NKX2-5 in regulating the human cardiac miRNAome

artículo científico publicado en 2019

The use of simultaneous reprogramming and gene correction to generate an osteogenesis imperfecta patient COL1A1 c. 3936 G>T iPSC line and an isogenic control iPSC line

scientific article published on 04 May 2019

This review explores the various stem and progenitor cell populations that are resident in the microvasculature, endothelium, and vessel walls

artículo científico publicado en 2009

Transcriptional profiling of mouse and human ES cells identifies SLAIN1, a novel stem cell gene.

artículo científico publicado en 2006

WNT3A promotes hematopoietic or mesenchymal differentiation from hESCs depending on the time of exposure

artículo científico publicado en 2013

WNT9A Is a Conserved Regulator of Hematopoietic Stem and Progenitor Cell Development

artículo científico publicado en 2018

β-cell regeneration and differentiation: how close are we to the 'holy grail'?

artículo científico publicado en 2014