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A novel ATM/TP53/p21-mediated checkpoint only activated by chronic γ-irradiation.

artículo científico publicado en 2014

Asymmetric nature of two subunits of RAD18, a RING-type ubiquitin ligase E3, in the human RAD6A-RAD18 ternary complex.

artículo científico publicado en 2011

Biochemical analysis of human PIF1 helicase and functions of its N-terminal domain.

artículo científico publicado en 2008

DNA replication-coupled PCNA mono-ubiquitination and polymerase switching in a human in vitro system.

artículo científico publicado en 2010

Different types of interaction between PCNA and PIP boxes contribute to distinct cellular functions of Y-family DNA polymerases

artículo científico publicado en 2015

Dynamics of human replication factors in the elongation phase of DNA replication

artículo científico publicado en 2007

Dynamics of the Interaction of Human Apurinic Endonuclease (Ape1) with Its Substrate and Product

artículo científico publicado el 13 de noviembre de 1998

En bloc transfer of polyubiquitin chains to PCNA in vitro is mediated by two different human E2-E3 pairs.

artículo científico publicado en 2012

Guanine- 5-carboxylcytosine base pairs mimic mismatches during DNA replication.

artículo científico publicado en 2014

Mechanisms of dCMP transferase reactions catalyzed by mouse Rev1 protein

scientific journal article

Molecular nature of radiation injury and DNA repair disorders associated with radiosensitivity.

artículo científico

Overexpression of Rev1 promotes the development of carcinogen-induced intestinal adenomas via accumulation of point mutation and suppression of apoptosis proportionally to the Rev1 expression level.

artículo científico publicado en 2017

Preferential digestion of PCNA-ubiquitin and p53-ubiquitin linkages by USP7 to remove polyubiquitin chains from substrates

artículo científico publicado en 2019

Rapid dissociation of human apurinic endonuclease (Ape1) from incised DNA induced by magnesium

artículo científico publicado en 1998

Regulation of DNA polymerase POLD4 influences genomic instability in lung cancer.

artículo científico publicado en 2010

Regulation of HLTF-mediated PCNA polyubiquitination by RFC and PCNA monoubiquitination levels determines choice of damage tolerance pathway

scientific article published on 01 November 2018

Relevance of simultaneous mono-ubiquitinations of multiple units of PCNA homo-trimers in DNA damage tolerance

artículo científico publicado en 2015

Repair synthesis step involving ERCC1-XPF participates in DNA repair of the Top1-DNA damage complex.

artículo científico publicado en 2015

Role of single-stranded DNA in targeting REV1 to primer termini

artículo científico publicado en 2006

Short CCG repeat in huntingtin gene is an obstacle for replicative DNA polymerases, potentially hampering progression of replication fork.

artículo científico publicado en 2015

Single-turnover analysis of mutant human apurinic/apyrimidinic endonuclease

artículo científico publicado en 1999

Spatiotemporal regulation of PCNA ubiquitination in damage tolerance pathways

artículo científico publicado en 2019

Stepwise multipolyubiquitination of p53 by the E6AP-E6 ubiquitin ligase complex

scientific article published on 06 September 2019

Strand breakage of a (6–4) photoproduct-containing DNA at neutral pH and its repair by the ERCC1–XPF protein complex

artículo científico publicado el 17 de abril de 2013

The Rev1 translesion synthesis polymerase has multiple distinct DNA binding modes

scientific article published on 12 July 2011

The first US-Japan meeting on error-prone DNA synthesis, Maui, Hawaii, December 20-21, 2004

artículo científico publicado en 2005

USP7 Is a Suppressor of PCNA Ubiquitination and Oxidative-Stress-Induced Mutagenesis in Human Cells.

artículo científico publicado en 2015