Lista de obras -

A Bone Morphogenetic Protein (BMP)-derived Peptide Based on the Type I Receptor-binding Site Modifies Cell-type Dependent BMP Signalling

artículo científico publicado en 2019

Advances in the molecular regulation of endothelial BMP9 signalling complexes and implications for cardiovascular disease

artículo científico publicado en 2019

Bone Morphogenetic Protein Type II Receptor Mutations Causing Protein Misfolding in Heritable Pulmonary Arterial Hypertension ⬇️

artículo científico publicado el 1 de noviembre de 2010

Bone morphogenetic protein 8B promotes the progression of non-alcoholic steatohepatitis

artículo científico publicado en 2020

Characterization of GDF2 Mutations and Levels of BMP9 and BMP10 in Pulmonary Arterial Hypertension

scientific article published on 01 March 2020

Circulating BMP9 Protects the Pulmonary Endothelium During Inflammation-induced Lung Injury in Mice

artículo científico publicado en 2020

Crystal structure of wild-type human thrombin in the Na+-free state.

artículo científico publicado en 2005

Crystal structures of BMPRII extracellular domain in binary and ternary receptor complexes with BMP10

artículo científico publicado en 2022

Crystal structures of protease nexin-1 in complex with heparin and thrombin suggest a 2-step recognition mechanism ⬇️

artículo científico publicado el 22 de mayo de 2012

Dual recognition and the role of specificity-determining residues in colicin E9 DNase-immunity protein interactions

artículo científico publicado en 1998

Highly discriminating protein-protein interaction specificities in the context of a conserved binding energy hotspot.

artículo científico publicado en 2004

Identification and structure of the anti-sigma factor-binding domain of the disulphide-stress regulated sigma factor sigma(R) from Streptomyces coelicolor

artículo científico publicado en 2002

Identification of rare sequence variation underlying heritable pulmonary arterial hypertension

artículo científico publicado en 2018

Increased Antielastase Activity in Idiopathic Pulmonary Arterial Hypertension and Chronic Thromboembolic Pulmonary Hypertension

artículo científico publicado en 2018

Letter by Morrell et al Regarding Article, "Selective BMP-9 Inhibition Partially Protects Against Experimental Pulmonary Hypertension"

artículo científico publicado en 2019

Molecular basis of ALK1-mediated signalling by BMP9/BMP10 and their prodomain-bound forms

scientific article published on 01 April 2020

Molecular basis of thrombin recognition by protein C inhibitor revealed by the 1.6-A structure of the heparin-bridged complex

artículo científico publicado en 2008

Regulation of bone morphogenetic protein 9 (BMP9) by redox-dependent proteolysis.

artículo científico publicado en 2014

Regulation of the ALK1 ligands, BMP9 and BMP10.

artículo científico publicado en 2016

Role of soluble endoglin in BMP9 signaling

scientific article published on 20 August 2019

Structural insights into the multiple functions of protein C inhibitor.

artículo científico publicado en 2009

Structure of the antithrombin-thrombin-heparin ternary complex reveals the antithrombotic mechanism of heparin.

artículo científico publicado en 2004

The Impact of Hypoxia on Neutrophil Degranulation and Consequences for the Host

artículo científico publicado en 2020

The Prodomain-bound Form of Bone Morphogenetic Protein 10 Is Biologically Active on Endothelial Cells

artículo científico publicado en 2015

The Role of zinc in the disulphide stress-regulated anti-sigma factor RsrA from Streptomyces coelicolor.

artículo científico publicado en 2003

The heparin binding site of protein C inhibitor is protease-dependent

artículo científico publicado en 2008

The promise of recombinant BMP ligands and other approaches targeting BMPR-II in the treatment of pulmonary arterial hypertension

artículo científico publicado en 2015

Thrombin inhibition by serpins disrupts exosite II

artículo científico publicado en 2010

Lista de obras de

A Bone Morphogenetic Protein (BMP)-derived Peptide Based on the Type I Receptor-binding Site Modifies Cell-type Dependent BMP Signalling

Advances in the molecular regulation of endothelial BMP9 signalling complexes and implications for cardiovascular disease

Bone Morphogenetic Protein Type II Receptor Mutations Causing Protein Misfolding in Heritable Pulmonary Arterial Hypertension ⬇️

Bone morphogenetic protein 8B promotes the progression of non-alcoholic steatohepatitis

Characterization of GDF2 Mutations and Levels of BMP9 and BMP10 in Pulmonary Arterial Hypertension

Circulating BMP9 Protects the Pulmonary Endothelium During Inflammation-induced Lung Injury in Mice

Crystal structure of wild-type human thrombin in the Na+-free state.

Crystal structures of BMPRII extracellular domain in binary and ternary receptor complexes with BMP10

Crystal structures of protease nexin-1 in complex with heparin and thrombin suggest a 2-step recognition mechanism ⬇️

Dual recognition and the role of specificity-determining residues in colicin E9 DNase-immunity protein interactions

Highly discriminating protein-protein interaction specificities in the context of a conserved binding energy hotspot.

Identification and structure of the anti-sigma factor-binding domain of the disulphide-stress regulated sigma factor sigma(R) from Streptomyces coelicolor

Identification of rare sequence variation underlying heritable pulmonary arterial hypertension

Increased Antielastase Activity in Idiopathic Pulmonary Arterial Hypertension and Chronic Thromboembolic Pulmonary Hypertension

Letter by Morrell et al Regarding Article, "Selective BMP-9 Inhibition Partially Protects Against Experimental Pulmonary Hypertension"

Molecular basis of ALK1-mediated signalling by BMP9/BMP10 and their prodomain-bound forms

Molecular basis of thrombin recognition by protein C inhibitor revealed by the 1.6-A structure of the heparin-bridged complex

Regulation of bone morphogenetic protein 9 (BMP9) by redox-dependent proteolysis.

Regulation of the ALK1 ligands, BMP9 and BMP10.

Role of soluble endoglin in BMP9 signaling

Structural insights into the multiple functions of protein C inhibitor.

Structure of the antithrombin-thrombin-heparin ternary complex reveals the antithrombotic mechanism of heparin.

The Impact of Hypoxia on Neutrophil Degranulation and Consequences for the Host

The Prodomain-bound Form of Bone Morphogenetic Protein 10 Is Biologically Active on Endothelial Cells

The Role of zinc in the disulphide stress-regulated anti-sigma factor RsrA from Streptomyces coelicolor.

The heparin binding site of protein C inhibitor is protease-dependent

The promise of recombinant BMP ligands and other approaches targeting BMPR-II in the treatment of pulmonary arterial hypertension

Thrombin inhibition by serpins disrupts exosite II