Lista de obras - Hermen Overkleeft - Dominio Público Uruguay

Accumulation of ubiquitin conjugates in a polyglutamine disease model occurs without global ubiquitin/proteasome system impairment

artículo científico publicado en 2009

Arg-Thz is a minimal substrate for the N(α),N(α)-arginyl methyltransferase involved in the biosynthesis of plantazolicin

artículo científico publicado en 2013

Chemical biology of antigen presentation by MHC molecules

artículo científico publicado en 2013

Chemically synthesized protein as tumour-specific vaccine: immunogenicity and efficacy of synthetic HPV16 E7 in the TC-1 mouse tumour model

artículo científico publicado en 2004

Chirality of TLR-2 ligand Pam3CysSK4 in fully synthetic peptide conjugates critically influences the induction of specific CD8+ T-cells

artículo científico publicado en 2008

Cleavable Crosslinkers as Tissue Fixation Reagents for Proteomic Analysis

artículo científico publicado en 2018

Combined Phosphoramidite-Phosphodiester Reagents for the Synthesis of Methylene Bisphosphonates

artículo científico publicado en 2017

Consequences of a global enzyme shortage of agalsidase beta in adult Dutch Fabry patients

artículo científico publicado en 2011

Discovery of an essential nucleotidylating activity associated with a newly delineated conserved domain in the RNA polymerase-containing protein of all nidoviruses

artículo científico publicado en 2015

Distinct uptake mechanisms but similar intracellular processing of two different toll-like receptor ligand-peptide conjugates in dendritic cells

artículo científico publicado en 2007

Downregulation of 26S proteasome catalytic activity promotes epithelial-mesenchymal transition

artículo científico publicado en 2016

Dynamic recruitment of active proteasomes into polyglutamine initiated inclusion bodies

artículo científico publicado en 2013

Efficient induction of antitumor immunity by synthetic toll-like receptor ligand-peptide conjugates

artículo científico publicado en 2014

Endo-β-Glucosidase Tag Allows Dual Detection of Fusion Proteins by Fluorescent Mechanism-Based Probes and Activity Measurement.

artículo científico publicado en 2016

From covalent glycosidase inhibitors to activity-based glycosidase probes.

artículo científico publicado en 2014

Glucosyl epi-cyclophellitol allows mechanism-based inactivation and structural analysis of human pancreatic α-amylase

artículo científico publicado en 2016

Glycosphingolipids and insulin resistance

artículo científico publicado en 2011

HEPES activates a MiT/TFE-dependent lysosomal-autophagic gene network in cultured cells: A call for caution.

artículo científico publicado en 2018

Identification of the non-lysosomal glucosylceramidase as beta-glucosidase 2

artículo científico publicado en 2007

Impairment of Immunoproteasome Function by Cigarette Smoke and in Chronic Obstructive Pulmonary Disease

artículo científico publicado en 2016

Inhibition of chymotryptic-like standard proteasome activity exacerbates doxorubicin-induced cytotoxicity in primary cardiomyocytes

artículo científico publicado en 2016

Intracellular bacterial growth is controlled by a kinase network around PKB/AKT1.

artículo científico publicado en 2007

Multiplex Fluorescent, Activity-Based Protein Profiling Identifies Active α-Glycosidases and Other Hydrolases in Plants.

artículo científico publicado en 2018

Near-infrared labeled, ovalbumin loaded polymeric nanoparticles based on a hydrophilic polyester as model vaccine: In vivo tracking and evaluation of antigen-specific CD8(+) T cell immune response.

artículo científico publicado en 2014

Pharmacological inhibition of glucosylceramide synthase enhances insulin sensitivity

artículo científico publicado en 2007

Photochemical generation of six- and five-membered cyclic vinyl cations

artículo científico publicado en 2006

Poly(ethylene glycol)-based stable isotope labeling reagents for the quantitative analysis of low molecular weight metabolites by LC-MS.

artículo científico publicado en 2008

Polyfluorinated bis-styrylbenzenes as amyloid-β plaque binding ligands

artículo científico publicado en 2014

Proteasome activity profiling: a simple, robust and versatile method revealing subunit-selective inhibitors and cytoplasmic, defense-induced proteasome activities

artículo científico publicado en 2009

Proteasome activity regulates CD8+ T lymphocyte metabolism and fate specification.

artículo científico publicado en 2017

Receptor-mediated targeting of cathepsins in professional antigen presenting cells

artículo científico publicado en 2009

Reciprocal chemical genetics for swift lead and target identification.

artículo científico publicado en 2008

Reducing glycosphingolipid content in adipose tissue of obese mice restores insulin sensitivity, adipogenesis and reduces inflammation

artículo científico publicado en 2009

Regulation of immunoproteasome function in the lung

artículo científico publicado en 2015

Solid-phase synthesis and purification of a set of uniformly 13C, 15N labelled de novo designed membrane fusogenic peptides

artículo científico publicado en 2007

Subclassification and biochemical analysis of plant papain-like cysteine proteases displays subfamily-specific characteristics.

artículo científico publicado en 2012

Subunit-selective proteasome activity profiling uncovers uncoupled proteasome subunit activities during bacterial infections.

artículo científico publicado en 2017

The DNAJB6 and DNAJB8 Protein Chaperones Prevent Intracellular Aggregation of Polyglutamine Peptides ⬇️

artículo científico publicado el 23 de abril de 2013

The antimalarial natural product symplostatin 4 is a nanomolar inhibitor of the food vacuole falcipains

artículo científico publicado en 2012

The cytosolic β-glucosidase GBA3 does not influence type 1 Gaucher disease manifestation

artículo científico publicado en 2010

The immunoproteasome controls the availability of the cardioprotective pattern recognition molecule Pentraxin3.

artículo científico publicado en 2015

The immunoproteasomes are key to regulate myokines and MHC class I expression in idiopathic inflammatory myopathies

artículo científico publicado en 2016

Transglycosidase activity of chitotriosidase: improved enzymatic assay for the human macrophage chitinase.

artículo científico publicado en 2003

Two in one: improving synthetic long peptide vaccines by combining antigen and adjuvant in one molecule

artículo científico publicado en 2014

Visualization of Active Glucocerebrosidase in Rodent Brain with High Spatial Resolution following In Situ Labeling with Fluorescent Activity Based Probes

artículo científico publicado en 2015

Lista de obras de Hermen Overkleeft

Accumulation of ubiquitin conjugates in a polyglutamine disease model occurs without global ubiquitin/proteasome system impairment

Arg-Thz is a minimal substrate for the N(α),N(α)-arginyl methyltransferase involved in the biosynthesis of plantazolicin

Chemical biology of antigen presentation by MHC molecules

Chemically synthesized protein as tumour-specific vaccine: immunogenicity and efficacy of synthetic HPV16 E7 in the TC-1 mouse tumour model

Chirality of TLR-2 ligand Pam3CysSK4 in fully synthetic peptide conjugates critically influences the induction of specific CD8+ T-cells

Cleavable Crosslinkers as Tissue Fixation Reagents for Proteomic Analysis

Combined Phosphoramidite-Phosphodiester Reagents for the Synthesis of Methylene Bisphosphonates

Consequences of a global enzyme shortage of agalsidase beta in adult Dutch Fabry patients

Discovery of an essential nucleotidylating activity associated with a newly delineated conserved domain in the RNA polymerase-containing protein of all nidoviruses

Distinct uptake mechanisms but similar intracellular processing of two different toll-like receptor ligand-peptide conjugates in dendritic cells

Downregulation of 26S proteasome catalytic activity promotes epithelial-mesenchymal transition

Dynamic recruitment of active proteasomes into polyglutamine initiated inclusion bodies

Efficient induction of antitumor immunity by synthetic toll-like receptor ligand-peptide conjugates

Endo-β-Glucosidase Tag Allows Dual Detection of Fusion Proteins by Fluorescent Mechanism-Based Probes and Activity Measurement.

From covalent glycosidase inhibitors to activity-based glycosidase probes.

Glucosyl epi-cyclophellitol allows mechanism-based inactivation and structural analysis of human pancreatic α-amylase

Glycosphingolipids and insulin resistance

HEPES activates a MiT/TFE-dependent lysosomal-autophagic gene network in cultured cells: A call for caution.

Identification of the non-lysosomal glucosylceramidase as beta-glucosidase 2

Impairment of Immunoproteasome Function by Cigarette Smoke and in Chronic Obstructive Pulmonary Disease

Inhibition of chymotryptic-like standard proteasome activity exacerbates doxorubicin-induced cytotoxicity in primary cardiomyocytes

Intracellular bacterial growth is controlled by a kinase network around PKB/AKT1.

Multiplex Fluorescent, Activity-Based Protein Profiling Identifies Active α-Glycosidases and Other Hydrolases in Plants.

Near-infrared labeled, ovalbumin loaded polymeric nanoparticles based on a hydrophilic polyester as model vaccine: In vivo tracking and evaluation of antigen-specific CD8(+) T cell immune response.

Pharmacological inhibition of glucosylceramide synthase enhances insulin sensitivity

Photochemical generation of six- and five-membered cyclic vinyl cations

Poly(ethylene glycol)-based stable isotope labeling reagents for the quantitative analysis of low molecular weight metabolites by LC-MS.

Polyfluorinated bis-styrylbenzenes as amyloid-β plaque binding ligands

Proteasome activity profiling: a simple, robust and versatile method revealing subunit-selective inhibitors and cytoplasmic, defense-induced proteasome activities

Proteasome activity regulates CD8+ T lymphocyte metabolism and fate specification.

Receptor-mediated targeting of cathepsins in professional antigen presenting cells

Reciprocal chemical genetics for swift lead and target identification.

Reducing glycosphingolipid content in adipose tissue of obese mice restores insulin sensitivity, adipogenesis and reduces inflammation

Regulation of immunoproteasome function in the lung

Solid-phase synthesis and purification of a set of uniformly 13C, 15N labelled de novo designed membrane fusogenic peptides

Subclassification and biochemical analysis of plant papain-like cysteine proteases displays subfamily-specific characteristics.

Subunit-selective proteasome activity profiling uncovers uncoupled proteasome subunit activities during bacterial infections.

The DNAJB6 and DNAJB8 Protein Chaperones Prevent Intracellular Aggregation of Polyglutamine Peptides ⬇️

The antimalarial natural product symplostatin 4 is a nanomolar inhibitor of the food vacuole falcipains

The cytosolic β-glucosidase GBA3 does not influence type 1 Gaucher disease manifestation

The immunoproteasome controls the availability of the cardioprotective pattern recognition molecule Pentraxin3.

The immunoproteasomes are key to regulate myokines and MHC class I expression in idiopathic inflammatory myopathies

Transglycosidase activity of chitotriosidase: improved enzymatic assay for the human macrophage chitinase.

Two in one: improving synthetic long peptide vaccines by combining antigen and adjuvant in one molecule

Visualization of Active Glucocerebrosidase in Rodent Brain with High Spatial Resolution following In Situ Labeling with Fluorescent Activity Based Probes