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Lista de obras de Steven J. Burakoff

54 Use of the HLA-DR antigens incorporated into liposomes to generate HLA-DR specific cytotoxic T lymphocytes

artículo científico publicado el 1 de enero de 1984

A CD8/Lck transgene is able to drive thymocyte differentiation

artículo científico publicado en 2006

A DC-specific cytolytic T lymphocyte line is OKT8+1

artículo científico publicado en 1983

A Remembrance of Baruj Benacerraf (AAI '57) 1920–2011

artículo científico publicado el 1 de diciembre de 2011

A comparative analysis of the phosphoinositide binding specificity of pleckstrin homology domains

artículo científico publicado en 1997

A distinct cytoplasmic domain of CD2 regulates ligand avidity and T-cell responsiveness to antigen

artículo científico publicado en 1992

A large proportion of T lymphocytes lack CD5 expression after bone marrow transplantation.

artículo científico publicado en 1989

A molecular analysis of the cytolytic T lymphocyte response

artículo científico publicado en 1984

A monoclonal antibody to LFA-3, the CD2 ligand, specifically immobilizes major histocompatibility complex proteins

scientific article published on 01 April 1989

A peptide library approach identifies a specific inhibitor for the ZAP-70 protein tyrosine kinase

artículo científico publicado en 2000

A perspective on HPK1 as a novel immuno-oncology drug target

artículo científico publicado en 2020

A role for calcineurin in degranulation of murine cytotoxic T lymphocytes

artículo científico publicado el 1 de abril de 1993

Abnormal cytolytic activity of lymphocyte function-associated antigen-1-deficient human cytolytic T lymphocyte clones.

artículo científico publicado en 1986

Absence of mitochondrial superoxide dismutase results in a murine hemolytic anemia responsive to therapy with a catalytic antioxidant

artículo científico publicado en 2001

Acute cutaneous graft-versus-host disease to minor histocompatibility antigens in a murine model. Evidence that large granular lymphocytes are effector cells in the immune response

artículo científico publicado en 1986

Acute graft-versus-host disease: pathogenesis and prevention with a monoclonal antibody in vivo

scientific article published on 01 February 1987

Adapting to multiple personalities: Cbl is also a RING finger ubiquitin ligase

artículo científico publicado en 2000

Adhesion of T lymphocytes to human endothelial cells is regulated by the LFA-1 membrane molecule

scientific article published on 01 February 1986

Adhesion receptors in lymphocyte activation.

artículo científico publicado en 1994

Alkylating HIV-1 Nef - a potential way of HIV intervention

artículo científico publicado en 2010

Alloreactive lymphocytes from T cell receptor (beta-chain) transgenic mice do not mediate a graft-versus-host reaction

artículo científico publicado en 1991

Alloreactivity studied with mutants of HLA-A2.

artículo científico publicado en 1989

Allospecific and virus-specific cytolytic T lymphocytes are restricted to the N or C1 domain of H-2 antigens expressed on L cells after DNA-mediated gene transfer.

scientific article published on May 1983

Alpha and beta subunits of the LFA-1 membrane molecule are involved in human monocyte-endothelial cell adhesion

scientific article published on 01 March 1987

Alpha particle radio-immunotherapy: animal models and clinical prospects

artículo científico publicado en 1989

Amelioration of acute graft vs host disease due to minor histocompatibility antigens by in vivo administration of anti-interleukin 2 receptor antibody

artículo científico publicado en 1986

Analysis of CD4 and CD2 receptor function

artículo científico publicado en 1988

Analysis of cross-reactive antigen-specific T cell clones. Specific recognition of two major histocompatibility complex (MHC) and two non-MHC antigens by a single clone

artículo científico publicado el 1 de junio de 1983

Analysis of the two-signal requirement for precursor cytolytic T lymphocyte activation using H-2Kk in liposomes

artículo científico publicado en 1982

Antigen-induced unresponsiveness results in altered T cell signaling

scientific article published on 01 December 1999

Antigen-presenting cell function in induction of helper T cells for cytotoxic T-lymphocyte responses: evidence for antigen processing

artículo científico publicado en 1981

Antigen-specific suppression of cytotoxic T cell responses: an idiotype-bearing factor regulates the cytotoxic T cell response to azobenzenearsonate-coupled cells

artículo científico publicado el 1 de marzo de 1982

B cell stimulatory factor-2 is involved in the differentiation of cytotoxic T lymphocytes

scientific article published on 01 January 1988

Basic science seminar: cytotoxic T-lymphocyte response to HLA antigens

scientific article published on 01 June 1983

Binding affinities of tyrosine-phosphorylated peptides to the COOH-terminal SH2 and NH2-terminal phosphotyrosine binding domains of Shc

artículo científico publicado en 1995

Biochemical and functional analyses of a secreted H-2Ld molecule

artículo científico publicado en 1986

Biodistribution studies of anti-Thy 1.2 IgM immunoconjugates: Implications for radioimmunotherapy

artículo científico publicado el 1 de agosto de 1988

Biological significance of alloreactivity: T cells stimulated by Sendai virus-coated syngeneic cells specifically lyse allogeneic target cells

artículo científico publicado el 1 de octubre de 1978

Bone marrow transplantation: the genetic and cellular basis of resistance to engraftment and acute graft-versus-host disease

artículo científico publicado en 1985

CD4 and signal transduction.

artículo científico publicado en 1996

CD4 phosphorylation partially reverses Nef down-regulation of CD4.

artículo científico publicado en 2004

CD4, CD8 and CD2 in T cell adhesion and signaling.

artículo científico publicado en 1993

CD43 regulates the threshold for T cell activation by targeting Cbl functions

artículo científico publicado el 9 de septiembre de 2011

CD43, a molecule defective in Wiskott-Aldrich syndrome, binds ICAM-1

artículo científico publicado el 21 de noviembre de 1991

CD43-mediated signals induce DNA binding activity of AP-1, NF-AT, and NFkappa B transcription factors in human T lymphocytes

artículo científico publicado en 2000

CD43-specific activation of T cells induces association of CD43 to Fyn kinase

artículo científico publicado en 1996

CD8 beta chain influences CD8 alpha chain-associated Lck kinase activity

artículo científico publicado en 1995

CPF-DD is an inhibitor of infection by human immunodeficiency virus and other enveloped viruses in vitro

artículo científico publicado el 1 de junio de 1992

CTL adhesion and antigen recognition are discrete steps in the human CTL-target cell interaction

scientific article published on 01 March 1987

Calcineurin phosphatase activity in T lymphocytes is inhibited by FK 506 and cyclosporin A

artículo científico publicado el 1 de mayo de 1992

Calcineurin regulation of the mammalian G0/G1 checkpoint element, cyclin dependent kinase 4.

artículo científico publicado en 2000

Cancer therapy from bench to bedside

artículo científico publicado en 2010

Cell-mediated cytotoxicity. An overview

scientific article published on 01 February 1984

Cell-mediated immunity to viral glycoproteins.

artículo científico publicado en 1980

Cellular interactions in the generation of cytolytic T lymphocyte responses. Analysis of the helper T cell pathway

artículo científico publicado en 1981

Cellular interactions in the generation of cytolytic T lymphocyte responses: role of Ia-positive splenic adherent cells in presentation in H-2 antigen

artículo científico publicado en 1980

Cellular interactions in the regulation of the cytolytic T-lymphocyte response: the effect of suboptimal antigen dose

scientific article published on 01 March 1981

Characterization of a mutant calcineurin A alpha gene expressed by EL4 lymphoma cells

artículo científico publicado en 1995

Cloning of p97/Gab2, the major SHP2-binding protein in hematopoietic cells, reveals a novel pathway for cytokine-induced gene activation

scientific journal article

Coexpression of the human HLA-A2 or HLA-B7 heavy chain gene and human beta 2-microglobulin gene in L cells

scientific article published on 01 December 1984

Constitutive activation of the Janus kinase-STAT pathway in T lymphoma overexpressing the Lck protein tyrosine kinase

artículo científico publicado el 1 de diciembre de 1997

Construction, expression and recognition of an H—2 molecule lacking its carboxyl terminus

scientific article published in Nature

Coreceptors and adapter proteins in T-cell signaling

artículo científico publicado en 1995

Correlation of calcineurin phosphatase activity and programmed cell death in murine T cell hybridomas

artículo científico publicado en 1992

Crk interacts with tyrosine-phosphorylated p116 upon T cell activation

artículo científico publicado en 1995

Cross-reactive lysis of trinitrophenyl (TNP)-derivatized H-2 incompatible target cells by cytolytic T lymphocytes generated against syngeneic TNP spleen cells

artículo científico publicado el 1 de diciembre de 1976

Cutaneous acute graft-versus-host disease to minor histocompatibility antigens in a murine model: histologic analysis and correlation to clinical disease

artículo científico publicado en 1986

Cutting edge: gab2 mediates an inhibitory phosphatidylinositol 3'-kinase pathway in T cell antigen receptor signaling

artículo científico publicado en 2000

Cyclosporin A and FK506: molecular mechanisms of immunosuppression and probes for transplantation biology.

artículo científico publicado en 1993

Cytolytic T lymphocyte recognition of subcellular antigen

scientific article published on 01 January 1982

Cytolytic T lymphocyte response to Moloney sarcoma virus

artículo científico publicado en 1983

Cytolytic pathways in haematopoietic stem-cell transplantation

artículo científico publicado en 2002

Cytosolic tyrosine dephosphorylation of STAT5. Potential role of SHP-2 in STAT5 regulation

artículo científico publicado en 2000

Cytotoxic T cells directed against HLA-DR antigens and their surface proteins.

artículo científico publicado en 1983

Cytotoxic T lymphocyte recognition of class I H-2 antigens after DNA-mediated gene transfer.

artículo científico publicado en 1984

Cytotoxic T lymphocyte recognition of transfected cells expressing a cloned retroviral gene

artículo científico publicado en 1983

Cytotoxic T lymphocytes induced against allogeneic I-region determinants react with Ia molecules on trinitrophenyl-conjugated syngeneic target cells

artículo científico publicado el 1 de agosto de 1977

Cytotoxic T lymphocytes specific for I region determinants do not require interactions with H-2K or D gene products

artículo científico publicado en 1977

Determination of junction avidity of cytolytic T cell and target cell

artículo científico publicado en 1986

Development and characterization of allospecific long-term human cytolytic T-cell lines

artículo científico publicado en 1980

Developmental control point in induction of thymic cortex regulated by a subpopulation of prothymocytes

artículo científico publicado en 1995

Differential activation of phosphotyrosine protein phosphatase activity in a murine T cell hybridoma by monoclonal antibodies to CD45

artículo científico publicado el 25 de marzo de 1992

Differential use of Fas ligand and perforin cytotoxic pathways by donor T cells in graft-versus-host disease and graft-versus-leukemia effect

scientific article published on 01 May 2001

Direct evidence for a receptor-ligand interaction between the T-cell surface antigen CD2 and lymphocyte-function-associated antigen 3.

artículo científico publicado en 1987

Direct evidence for binding of CD8 to HLA class I antigens

artículo científico publicado en 1989

Disruption of T cell development and repertoire selection by calcineurin inhibition in vivo.

artículo científico publicado en 1994

Disruption of the CD4-p56lck complex is required for rapid internalization of CD4

artículo científico publicado el 15 de agosto de 1992

Dissection of immune gene networks in primary melanoma tumors critical for antitumor surveillance of patients with stage II-III resectable disease

artículo científico

Dissection of serological and cytolytic T lymphocyte epitopes on murine major histocompatibility antigens by a recombinant H-2 gene separating the first two external domains

artículo científico publicado en 1984

Distinct effects of interferon-gamma and MHC class I surface antigen levels on resistance of the K562 tumor cell line to natural killer-mediated lysis

artículo científico publicado en 1990

Distinct roles for L3T4 in T cell activation.

artículo científico publicado en 1987

Dynamic changes in viscoelastic properties in cytotoxic T-lymphocyte-mediated killing

artículo científico publicado en 1988

Effect of anti-IL-2Ralpha antibody on IL-2-induced Jak/STAT signaling

artículo científico publicado en 2002

Effect of timing of lymphokine presentation on generation of cytotoxic T lymphocytes

artículo científico publicado en 1989

Efficient conjugation of DTPA to an IgM monoclonal antibody in ascites fluid

artículo científico publicado en 1988

Engraftment following T cell-depleted bone marrow transplantation. III. Differential effects of increased total-body irradiation on semiallogeneic and allogeneic recipients

artículo científico publicado en 1988

Engraftment following T-cell-depleted bone marrow transplantation. II. Stability of mixed chimerism in semiallogeneic recipients after total-body irradiation

artículo científico publicado en 1987

Engraftment following T-cell-depleted marrow transplantation. I. The role of major and minor histocompatibility barriers

artículo científico publicado en 1987

Enhanced allostimulatory activity of host antigen-presenting cells in old mice intensifies acute graft-versus-host disease

artículo científico publicado en 2002

Enhancement of T-cell activation by the CD43 molecule whose expression is defective in Wiskott-Aldrich syndrome

artículo científico publicado en 1991

Evidence for a Requirement for Both Phospholipid and Phosphotyrosine Binding via the Shc Phosphotyrosine-Binding Domain In Vivo

artículo científico publicado el 1 de septiembre de 1997

Evidence for a physical association between the Shc-PTB domain and the beta c chain of the granulocyte-macrophage colony-stimulating factor receptor

scientific journal article

Evidence for a role for the phosphotyrosine-binding domain of Shc in interleukin 2 signaling

artículo científico publicado en 1996

Evidence for differential intracellular signaling via CD4 and CD8 molecules

artículo científico publicado en 1994

Evidence that anti-LFA-1 in vivo improves engraftment and survival after allogeneic bone marrow transplantation

artículo científico publicado en 1990

Evidence that anti-asialo GM1 in vivo improves engraftment of T cell-depleted bone marrow in hybrid recipients.

artículo científico publicado en 1990

Evidence that large granular lymphocytes of donor origin mediate acute graft-versus-host disease

scientific article published on 01 January 1989

Experimental evidence for the potential usefulness of permanent IL-3-dependent multipotential hematopoietic progenitor cell lines in transfusion granulocyte support therapy: need for expansion of early passage cells

artículo científico publicado el 1 de enero de 1984

Expression and CTL recognition of cloned subgenomic fragments of Moloney murine leukemia virus in murine cells

artículo científico publicado en 1985

Expression and function of CD4 in a murine T-cell hybridoma

artículo científico publicado en 1987

Expression and function of CD8 in a murine T cell hybridoma

artículo científico publicado en 1987

Expression and function of a CD 5 cDNA in human and murine T cells

article

Expression and induction of nuclear factor-kappa B-related proteins in thymocytes

artículo científico publicado en 1995

Expression and ontogeny of CD2 on murine B cells.

artículo científico publicado en 1990

Expression and ontogeny of murine CD2

artículo científico publicado en 1989

Expression of CD5 regulates responsiveness to IL-1.

artículo científico publicado en 1988

Expression of the T-cell surface molecule CD2 and an epitope-loss CD2 mutant to define the role of lymphocyte function-associated antigen 3 (LFA-3) in T-cell activation

artículo científico publicado en 1988

Expression of the T-cell-specific gamma gene is unnecessary in T cells recognizing class II MHC determinants

artículo científico publicado en 1985

FK 506 and rapamycin: molecular probes of T-lymphocyte activation

artículo científico publicado el 1 de diciembre de 1991

FK506 binding protein 12 mediates sensitivity to both FK506 and rapamycin in murine mast cells

artículo científico publicado en 1995

FK506 inhibits antigen receptor-mediated induction of c-rel in B and T lymphoid cells

artículo científico publicado en 1995

Fas ligand-deficient gld mice are more susceptible to graft-versus-host-disease

artículo científico publicado en 2000

Fas-deficient lpr mice are more susceptible to graft-versus-host disease

scientific article published on 01 January 2000

Fratricide of CD8+ cytotoxic T lymphocytes is dependent on cellular activation and perforin-mediated killing

artículo científico publicado en 2004

From bytes to bedside: data integration and computational biology for translational cancer research

artículo científico publicado en 2007

Functional CD2 mutants unable to bind to, or be stimulated by, LFA-3

artículo científico publicado el 15 de febrero de 1990

Functional T cell deficits after bone marrow transplantation across minor histocompatibility barriers: effects of graft-vs-host disease on precursor frequency of reactive cells

artículo científico publicado en 1987

Functional analysis of CD2, CD4, and CD8 in T-cell activation

artículo científico publicado en 1988

Functional analysis of a cytoplasmic domain-deleted mutant of the CD4 molecule

artículo científico publicado en 1988

Functional assessment of T cell depletion from bone marrow prior to therapeutic transplantation using limiting dilution culture methods

scientific article published on 01 October 1986

Functional distinctions between the LFA-1, LFA-2, and LFA-3 membrane proteins on human CTL are revealed with trypsin-pretreated target cells.

artículo científico publicado en 1985

Functional expression of human CD8 in fully reconstituted mice after retroviral-mediated gene transfer of hemopoietic stem cells

artículo científico publicado el 15 de julio de 1992

Gene mapping and somatic cell hybrid analysis of the role of human lymphocyte function-associated antigen-3 (LFA-3) in CTL-target cell interactions

artículo científico publicado en 1986

Generation of cytolytic T lymphocytes after reovirus infection: role of S1 gene

artículo científico publicado el 1 de enero de 1979

Generation of cytolytic T lymphocytes in thymectomized, irradiated, and bone marrow-reconstituted mice

artículo científico publicado en 1982

Generation of long-term human cytolytic cell lines with persistent natural killer activity.

artículo científico publicado en 1982

Genetic control of cytolytic T lymphocyte responses. III. The role of K and I region alleles on the specificity of the cytolytic T lymphocyte response to trinitrophenyl-modified syngeneic cells

scientific article published on 01 October 1980

Genetic control of cytolytic T-lymphocyte responses. I. Ir gene control of the specificity of cytolytic T-lymphocyte responses to trinitrophenyl-modified syngeneic cells

artículo científico publicado el 1 de agosto de 1978

Genetic control of cytolytic t-lymphocyte responses. II. The role of the host genotype in parental leads to F1 radiation chimeras in the control of the specificity of cytolytic T-lymphocyte responses to trinitrophenyl-modified syngeneic cells

artículo científico publicado el 1 de agosto de 1978

Genetic control of the cytolytic T lymphocyte response to influenza viruses: H-2 genes influence the response to H-2Kb plus virus

artículo científico publicado el 1 de mayo de 1982

Glycolipid-anchored form of CD4 increases intercellular adhesion but is unable to enhance T cell activation

artículo científico publicado el 15 de julio de 1991

Glycoproteins of 210,000 and 130,000 m.w. on activated T cells: cell distribution and antigenic relation to components on resting cells and T cell lines

artículo científico publicado el 1 de junio de 1984

Graft-versus-host-disease-associated thymic damage results in the appearance of T cell clones with anti-host reactivity

artículo científico publicado en 2000

Growth-inhibitory activity of lymphoid cell plasma membranes. II. Partial characterization of the inhibitor

artículo científico publicado el 1 de octubre de 1984

H-2Ld antigen encoded by a recombinant retrovirus genome is expressed on the surface of infected cells

artículo científico publicado en 1985

HIV Nef-mediated CD4 down-regulation is adaptor protein complex 2 dependent

artículo científico publicado en 2005

HIV-gp120 can block CD4-class II MHC-mediated adhesion

artículo científico publicado en 1990

HPK1 Influences Regulatory T Cell Functions

scientific article published on 06 July 2020

HPK1 as a novel target for cancer immunotherapy

artículo científico publicado el 1 de diciembre de 2012

Hematopoietic progenitor kinase 1 (HPK1) negatively regulates prostaglandin E2-induced fos gene transcription

artículo científico publicado en 2003

Hematopoietic progenitor kinase 1 is a critical component of prostaglandin E2-mediated suppression of the anti-tumor immune response

artículo científico publicado en 2009

Hematopoietic progenitor kinase 1 is a negative regulator of dendritic cell activation

artículo científico publicado en 2009

Heritable lymphocyte function-associated antigen-1 deficiency: abnormalities of cytotoxicity and proliferation associated with abnormal expression of LFA-1

artículo científico publicado en 1985

Human 70-kDa SHP-1L differs from 68-kDa SHP-1 in its C-terminal structure and catalytic activity

artículo científico publicado en 1999

Human cytolytic T lymphocyte interactions with vascular endothelium and fibroblasts: role of effector and target cell molecules

artículo científico publicado en 1984

Human dermal fibroblasts present tetanus toxoid antigen to antigen-specific T cell clones

artículo científico publicado en 1985

Human immunodeficiency virus infection is efficiently mediated by a glycolipid-anchored form of CD4.

artículo científico publicado en 1990

Human lymphocyte function associated antigen-1 (LFA-1): identification of multiple antigenic epitopes and their relationship to CTL-mediated cytotoxicity

artículo científico publicado el 1 de septiembre de 1983

Human lymphocyte function associated antigens

artículo científico publicado el 1 de enero de 1984

Ia expression by vascular endothelium is inducible by activated T cells and by human gamma interferon

artículo científico publicado en 1983

Identification and structural analysis of residues in the V1 region of CD4 involved in interaction with human immunodeficiency virus envelope glycoprotein gp120 and class II major histocompatibility complex molecules

artículo científico publicado en 1990

Identification of a novel binding site between HIV type 1 Nef C-terminal flexible loop and AP2 required for Nef-mediated CD4 downregulation

artículo científico publicado en 2012

Identification of a physical interaction between calcineurin and nuclear factor of activated T cells (NFATp)

scientific journal article

Immunochemically purified DR antigens in liposomes stimulate xenogeneic cytolytic T cells in secondary in vitro cultures

artículo científico publicado en 1986

Immunodeficiency in graft-versus-host disease. I. Mechanism of immune suppression

scientific article published on 01 May 1988

Immunophilins in protein folding and immunosuppression.

artículo científico publicado en 1994

In vitro generation of helper T cells and suppressor T cells that regulate the cytolytic T lymphocyte response to trinitrophenyl-modified syngeneic cells

artículo científico publicado en 1982

Increasing T-cell age reduces effector activity but preserves proliferative capacity in a murine allogeneic major histocompatibility complex-mismatched bone marrow transplant model

artículo científico publicado en 2004

Induction of HLA class I surface expression recruits low-affinity cytolytic T lymphocytes

artículo científico publicado en 1990

Induction of alloantigen-specific tolerance by B cells from CD40-deficient mice

artículo científico publicado en 1996

Induction of allogeneic cytolytic T lymphocytes by partially purified membrane glycoproteins

scientific article published on 01 April 1980

Induction of secondary cytotoxic T lymphocytes by liposomes containing HLA-DR antigens.

artículo científico publicado en 1980

Induction of secondary cytotoxic T lymphocytes by purified HLA-A and HLA-B antigens reconstituted into phospholipid vesicles

artículo científico publicado el 1 de noviembre de 1978

Inhibition of CD4+ T cell function by the HIV envelope protein, gp120

artículo científico publicado en 1988

Inhibition of cell-mediated cytolysis of trinitrophenyl-derivatized target cells by alloantisera directed to the products of the K and D loci of the H-2 complex

artículo científico publicado el 1 de febrero de 1976

Inhibition of interleukin-1 by an interleukin-1 receptor antagonist prevents graft-versus-host disease

artículo científico publicado en 1991

Inhibition of lymphokine-activated killer cell-mediated cytotoxicity by phorbol ester

artículo científico publicado en 1989

Inhibition of normal lymphocyte responses by cell membranes

artículo científico publicado el 1 de noviembre de 1984

Inhibition of the induction of cytolytic T lymphocytes with alloantisera directed against H-2K and H-2D gene products

artículo científico publicado el 1 de mayo de 1978

Interaction of CD2 with its ligand lymphocyte function-associated antigen-3 induces adenosine 3',5'-cyclic monophosphate production in T lymphocytes

artículo científico publicado el 1 de julio de 1991

Interaction of CD2 with its ligand, LFA-3, in human T cell proliferation

artículo científico publicado en 1988

Interaction of Shc with Grb2 regulates association of Grb2 with mSOS

scientific journal article

Interaction of Shc with Grb2 regulates the Grb2 association with mSOS

artículo científico publicado en 1995

Interaction of Shc with the zeta chain of the T cell receptor upon T cell activation

artículo científico publicado en 1993

Interactions of T lymphocytes with human vascular endothelial cells: role of endothelial cells surface antigens.

artículo científico publicado en 1984

Interferon-gamma induction of LFA-1-mediated homotypic adhesion of human monocytes

scientific article published on 01 July 1986

Interleukin-3 (IL-3)-induced c-fos activation is modulated by Gab2-calcineurin interaction

artículo científico publicado en 2008

Interruption of the sequential release of small and large molecules from tumor cells by low temperature during cytolysis mediated by immune T-cells or complement

artículo científico publicado en 1974

Intracellular signaling consequences of anti-IL-2Ralpha blockade by daclizumab

artículo científico publicado en 2001

Intrathymic signals in thymocytes are mediated by p38 mitogen-activated protein kinase.

artículo científico publicado en 1996

Involvement of proteasomes in regulating Jak-STAT pathways upon interleukin-2 stimulation.

artículo científico publicado en 1997

Ir gene control of the cytotoxic T lymphocyte response to Sendai virus: H-2k mice are low responders to Sendai

artículo científico publicado el 1 de diciembre de 1981

Irradiated B7-1 transduced primary acute myelogenous leukemia (AML) cells can be used as therapeutic vaccines in murine AML

artículo científico publicado en 1996

Is the primary complement lesion insufficient for lysis? Failure of cells damaged under osmotic protection to lyse in EDTA or at low temperature after removal of osmotic protection

artículo científico publicado en 1975

LFA-1 membrane molecule in the regulation of homotypic adhesions of human B lymphocytes

artículo científico publicado en 1985

LFA-1, LFA-2, and LFA-3 antigens are involved in CTL-target conjugation.

artículo científico publicado en 1984

Lack of SHPTP1 results in src-family kinase hyperactivation and thymocyte hyperresponsiveness

artículo científico publicado en 1996

Lateral mobility of class I histocompatibility antigens in B lymphoblastoid cell membranes: modulation by cross-linking and effect of cell density

artículo científico publicado en 1987

Lck-dependent tyrosyl phosphorylation of the phosphotyrosine phosphatase SH-PTP1 in murine T cells

artículo científico publicado en 1994

Lipid raft distribution of CD4 depends on its palmitoylation and association with Lck, and evidence for CD4-induced lipid raft aggregation as an additional mechanism to enhance CD3 signaling

artículo científico publicado en 2003

Localization of the FK506-binding protein, FKBP 13, to the lumen of the endoplasmic reticulum

artículo científico publicado en 1993

Long-lasting deficit of functional T cell precursors in human bone marrow transplant recipients revealed by limiting dilution methods

scientific article published on 01 June 1986

Long-term human cytolytic T-cell lines allospecific for HLA-DR6 antigen are OKT4+.

artículo científico publicado en 1982

Loss of normal thymic repertoire selection and persistence of autoreactive T cells in graft vs host disease

artículo científico publicado en 1994

Lymphocytes recognize human vascular endothelial and dermal fibroblast Ia antigens induced by recombinant immune interferon

scientific article published in Nature

Lymphocytes with a CD4+ CD8- CD3- phenotype are effectors of experimental cutaneous graft-versus-host disease

artículo científico publicado el 1 de diciembre de 1991

Lymphoid irradiation results in long-term increases in natural killer cells in patients treated for Hodgkin's disease

artículo científico publicado el 1 de febrero de 1992

Lysine 144, a ubiquitin attachment site in HIV-1 Nef, is required for Nef-mediated CD4 down-regulation

artículo científico publicado en 2008

Major histocompatibility complex products restrict the adherence of cytolytic T lymphocytes to minor histocompatibility antigens or to trinitrophenyl determinants on schistosomula of Schistosoma mansoni

artículo científico publicado el 1 de abril de 1979

Mapping functional epitopes of the human LFA-1 glycoprotein: monoclonal antibody inhibition of NK and CTL effectors

artículo científico publicado en 1986

Measurement of Calcineurin Phosphatase Activity in Cell Extracts

artículo científico publicado en 1996

Mechanisms of immunosuppression by FK506. Preservation of T cell transmembrane signal transduction

artículo científico publicado el 1 de junio de 1990

Membrane-bound anti-CD3 monoclonal antibodies trigger cytolytic T-lymphocyte-mediated tumor lysis

artículo científico publicado en 1988

Molecular and biological actions of cyclosporin A and FK506 on T cell development and function

artículo científico publicado en 1994

Molecular cloning of a 25-kDa high affinity rapamycin binding protein, FKBP25

artículo científico publicado el 5 de junio de 1992

Molecular cloning of a membrane-associated human FK506- and rapamycin-binding protein, FKBP-13

artículo científico publicado en 1991

Monoallelic Expression of the Interleukin-2 Locus

artículo científico publicado el 27 de marzo de 1998

Mouse cytolytic T lymphocytes induced by xenogeneic rat stimulator cells exhibit specificity for H-2 complex alloantigens

artículo científico publicado en 1977

Multiple conformational states of the HPK1 kinase domain in complex with sunitinib reveal the structural changes accompanying HPK1 trans-regulation

scientific article published on 24 April 2019

Murine CD2: structure, expression, and recognition of human LFA-3.

artículo científico publicado en 1989

Mutants of HLA-A2 in the analysis of its structure and function

artículo científico publicado en 1989

NFATc2-mediated repression of cyclin-dependent kinase 4 expression

scientific journal article

Natural killer cell development is blocked in the context of aberrant T lymphocyte ontogeny

artículo científico publicado en 1996

Nicotine activates nuclear factor of activated T cells c2 (NFATc2) and prevents cell cycle entry in T cells

artículo científico publicado en 2004

Non-MHC-restricted target-cell lysis by a CD4-CD8- TCR alpha beta T-cell line, as well as by TCR gamma delta T-cell lines, results from lymphokine-activated killing

artículo científico publicado en 1991

Non-MHC-restricted target-cell lysis by a CD4−CD− TCRαβ T-cell line, as well as by TCR4gMδ T-cell lines, results from lymphokine-activated killing

Non-invasive in vivo imaging for liver tumour progression using an orthotopic hepatocellular carcinoma model in immunocompetent mice

artículo científico publicado en 2011

Novel subsets of human T cells (CD4+ CD8+ TCRγδ and CD4− CD8− TCRαβ) and T-cell development

Novel subsets of human T cells (CD4+ CD8- TCR gamma delta and CD4- CD8- TCR alpha beta) and T-cell development

artículo científico

Nuclear factors that mediate intrathymic signals are developmentally regulated

artículo científico publicado en 1994

Partial deletions of the cytoplasmic domain of CD2 result in a partial defect in signal transduction

artículo científico publicado en 1990

Phenotypic and functional analysis of expanded natural killer cell subpopulations in Hodgkin's disease patients treated with lymphoid irradiation

artículo científico publicado en 1993

Phenotypic and functional characterization of human cytolytic T cells lacking expression of CD5.

artículo científico publicado en 1988

Phytohaemagglutinin activation of T cells through the sheep red blood cell receptor

artículo científico publicado en 1985

Positive and negative signaling pathways

artículo científico publicado en 1999

Prevention of HIV-1 infection and preservation of CD4 function by the binding of CPFs to gp120.

artículo científico publicado en 1990

Probing Immunosuppressant Action with a Nonnatural Immunophilin Ligand

artículo científico publicado el 26 de octubre de 1990

Production of colony-stimulating factor(s) for granulocyte-macrophage and multipotential (granulocyte/erythroid/megakaryocyte/macrophage) hematopoietic progenitor cells (CFU-GEMM) by clonal lines of human IL-2-dependent T-lymphocytes

scientific article published on 01 October 1984

Prostaglandin E2 activates HPK1 kinase activity via a PKA-dependent pathway

artículo científico publicado en 2007

Protein kinase C required for cytotoxic T lymphocyte triggering

artículo científico publicado en 1987

Radioimmunotherapy with alpha-particle-emitting immunoconjugates

artículo científico publicado en 1988

Rapamycin and FK506 binding proteins (immunophilins)

article

Rapamycin-resistant proliferation of CD8+ T cells correlates with p27kip1 down-regulation and bcl-xL induction, and is prevented by an inhibitor of phosphoinositide 3-kinase activity

artículo científico publicado en 2003

Recapitulation of the immune response and haematopoietic system in bone marrow transplantation

artículo científico publicado en 1983

Recognition of HLA-A2 and -B7 antigens by cloned cytotoxic T lymphocytes after gene transfer into human and monkey, but not mouse, cells

artículo científico publicado en 1984

Recognition of HLA-A2 mutant and variant target cells by an HLA-A2 allospecific human cytotoxic T lymphocyte line

artículo científico publicado el 1 de septiembre de 1983

Recognition of interspecies hybrid class I histocompatibility antigens by antigen-specific cytolytic T lymphocytes

scientific article published on September 1985

Recognition of the alpha-1 and alpha-2 domains of H-2 molecules by allospecific cloned T cells

Regulation of Cbl molecular interactions by the co-receptor molecule CD43 in human T cells

artículo científico publicado en 2001

Regulation of cytotoxic T lymphocyte-mediated graft rejection following bone marrow transplantation.

artículo científico publicado en 1988

Regulation of tyrosine phosphorylation in isolated T cell membrane by inhibition of protein tyrosine phosphatases

artículo científico publicado el 15 de agosto de 1998

Requirement for Shc in TCR-mediated activation of a T cell hybridoma

artículo científico publicado en 1999

Requirement for three distinct lymphokines for the induction of cytotoxic T lymphocytes from thymocytes

scientific article published on 01 December 1986

Requirements for modulation of the CD4 molecule in response to phorbol myristate acetate. Role of the cytoplasmic domain

scientific article published on 01 March 1989

Responses to the H–2Kba mutant involve recognition of syngeneic Ia molecules

artículo científico publicado el 1 de mayo de 1983

Retarded recovery of functional T cell frequencies in T cell-depleted bone marrow transplant recipients

artículo científico publicado en 1987

Retrovirus-induced changes in major histocompatibility complex antigen expression influence susceptibility to lysis by cytotoxic T lymphocytes

artículo científico publicado en 1985

Role of L3T4 in antigen-driven activation of a class I-specific T cell hybridoma

artículo científico publicado en 1985

Role of syngeneic Ia+ accessory cells in the generation of allospecific CTL responses

artículo científico publicado en 1982

Role of the Lck Src homology 2 and 3 domains in protein tyrosine phosphorylation

artículo científico publicado en 1996

SLAP, a dimeric adapter protein, plays a functional role in T cell receptor signaling

artículo científico publicado en 1999

SOD2-deficiency anemia: protein oxidation and altered protein expression reveal targets of damage, stress response, and antioxidant responsiveness

scientific journal article

Severe colitis in mice with aberrant thymic selection

artículo científico publicado en 1995

Sialophorin, a surface sialoglycoprotein defective in the Wiskott-Aldrich syndrome, is involved in human T lymphocyte proliferation

artículo científico publicado en 1987

Signal transduction pathways involved in T cell receptor-induced regulation of CD2 avidity for CD58

artículo científico publicado el 1 de abril de 1993

Signaling T-cell survival and death by IL-2 and IL-15.

artículo científico publicado en 2005

Site-directed mutagenesis of class I HLA genes. Role of glycosylation in surface expression and functional recognition

artículo científico publicado en 1987

Solution structure of the Shc SH2 domain complexed with a tyrosine-phosphorylated peptide from the T-cell receptor

artículo científico publicado en 1995

Species-restricted recognition of transfected HLA-A2 and HLA-B7 by human CTL clones

Specificity of OKT4+ cytotoxic T lymphocyte clones

artículo científico publicado en 1982

Specificity of alloreactive T lymphocytes that adhere to lung stage schistosomula of Schistosoma mansoni

scientific article published on 01 May 1980

Specificity of mouse cytotoxic T lymphocytes stimulated with either HLA-A and -B or HLA-DR antigens reconstituted into phospholipid vesicles

scientific article published on 01 August 1980

Specificity of rat xenogeneic cell-mediated cytolysis for the products of the K and D loci of the mouse H-2 complex

artículo científico publicado el 1 de mayo de 1977

Specificity of the helper T cell for the cytolytic T lymphocyte response to influenza viruses.

artículo científico publicado en 1981

Spontaneous aggregation as a mechanism for human monocyte purification

artículo científico publicado en 1986

Stimulation of secondary anti-MSV cytolytic T lymphocytes with MBL-2 reconstituted membranes

artículo científico publicado en 1983

Structural organization of the genes encoding human and murine FK506-binding protein (FKBP) 13 and comparison to FKBP1.

artículo científico publicado en 1993

Structure and ligand recognition of the phosphotyrosine binding domain of Shc

artículo científico publicado en 1995

Structure of the amino-terminal domain of Cbl complexed to its binding site on ZAP-70 kinase

artículo científico publicado en 1999

Suppression of anti-hapten antibody responses by hapten-specific cytolytic T lymphocytes: role of I-A-associated antigen on target B lymphocytes

artículo científico publicado el 1 de julio de 1982

Synergistic T cell activation via the physiological ligands for CD2 and the T cell receptor

artículo científico publicado en 1988

T Cell Activation through the CD43 Molecule Leads to Vav Tyrosine Phosphorylation and Mitogen-activated Protein Kinase Pathway Activation

artículo científico publicado el 5 de junio de 1998

T cell adhesion molecules

artículo científico publicado en 1988

T cell hybridomas define the class II MHC-restricted response to vesicular stomatitis virus infection

artículo científico publicado en 1988

T cell receptors: adhesion and signaling

artículo científico publicado en 1991

T cell surface molecules regulating noncognate B lymphocyte activation. Role of CD2 and LFA-1.

artículo científico publicado en 1992

T lymphocyte-mediated suppression of myeloma function in vitro. II. Evidence for regulation of hapten-binding myelomas by syngeneic hapten-specific cytolytic T lymphocytes

artículo científico publicado el 1 de agosto de 1980

T lymphocyte-mediated suppression of myeloma function in vitro. III. Regulation of antibody production in hybrid myeloma cells by T lymphocytes

artículo científico publicado el 1 de octubre de 1980

T-cell receptor-CD4 physical association in a murine T-cell hybridoma: induction by antigen receptor ligation

artículo científico publicado en 1989

T-lymphocyte activation: the biology and function of CD2 and CD4.

artículo científico publicado en 1989

T3 monoclonal antibody activation of nonspecific cytolysis: a mechanism of CTL inhibition

artículo científico publicado en 1985

Targeting Src homology 2 domain-containing tyrosine phosphatase (SHP-1) into lipid rafts inhibits CD3-induced T cell activation

artículo científico publicado en 2001

The 25-kDa FK506-binding protein is localized in the nucleus and associates with casein kinase II and nucleolin

artículo científico publicado el 15 de agosto de 1993

The CD4 molecule is not always required for the T cell response to bacterial enterotoxins

artículo científico publicado en 1991

The Small GTP-Binding Protein Rho Potentiates AP-1 Transcription in T Cells

artículo científico publicado el 1 de septiembre de 1998

The Structure of HPK1 Kinase Domain: To Boldly Go Where No Immuno-Oncology Drugs Have Gone Before

artículo científico publicado en 2019

The ability of Ia and H-2Kk-bearing membranes to replace the antigen-presenting cell in an H-2Kk allogeneic cytotoxic T cell response

scientific article published on 01 October 1985

The adapter protein Shc interacts with the interleukin-2 (IL-2) receptor upon IL-2 stimulation

artículo científico publicado en 1994

The alpha-3 domain of class I MHC proteins influences cytotoxic T lymphocyte recognition of antigenic determinants located within the alpha-1 and alpha-2 domains

artículo científico publicado en 1988

The biologic roles of CD2, CD4, and CD8 in T-cell activation

artículo científico

The biologic significance of alloreactivity. The ontogeny of T-cell sets specific for alloantigens or modified self antigens

artículo científico publicado el 1 de noviembre de 1978

The complex of FK506-binding protein 12 and FK506 inhibits calcineurin phosphatase activity and IgE activation-induced cytokine transcripts, but not exocytosis, in mouse mast cells.

artículo científico publicado en 1995

The cytolytic T lymphocyte response to trinitrophenyl-modified syngeneic cells. I. Evidence for antigen-specific helper T cells

artículo científico publicado el 1 de septiembre de 1979

The cytolytic T lymphocyte response to trinitrophenyl-modified syngeneic cells. II. Evidence for antigen-specific suppressor T cells

artículo científico publicado el 1 de septiembre de 1979

The cytoplasmic domain of CD4 is required for stable association with the lymphocyte-specific tyrosine protein kinase p56lck

artículo científico publicado en 1990

The cytoplasmic domain of CD8 beta regulates Lck kinase activation and CD8 T cell development

artículo científico publicado el 1 de julio de 1998

The effect of the immunosuppressant FK-506 on alternate pathways of T cell activation

artículo científico publicado en 1991

The extracellular signal-regulated kinase pathway is required for activation-induced cell death of T cells

artículo científico publicado en 1999

The function of LFA-1 in cell-mediated killing and adhesion: studies on heritable LFA-1, Mac-1 deficiency and on lymphoid cell self-aggregation

artículo científico publicado en 1985

The functional significance, distribution, and structure of LFA-1, LFA-2, and LFA-3: cell surface antigens associated with CTL-target interactions

article

The human HLA-specific monoclonal antibody W6/32 recognizes a discontinuous epitope within the alpha 2 domain of murine H-2Db

scientific article published on 01 January 1986

The immune response to Moloney murine leukemia virus-induced tumors: induction of cytolytic T lymphocytes specific for both viral and tumor-associated antigens

artículo científico publicado en 1986

The induction of cytolytic T lymphocytes with purified plasma membranes

artículo científico publicado en 1978

The induction of cytolytic T lymphocytes with specificity for p-azophenylarsonate coupled syngeneic cells

artículo científico publicado el 1 de octubre de 1978

The induction of cytolytic T lymphocytes with syngeneic trinitrophenyl-coupled membranes

artículo científico publicado el 1 de julio de 1979

The induction of secondary cytolytic T lymphocytes by solubilized membrane proteins

artículo científico publicado el 1 de marzo de 1978

The induction of virus-specific cytotoxic T lymphocytes with solubilized viral and membrane proteins

artículo científico publicado el 1 de diciembre de 1978

The interaction of CD4 with HIV-1 gp120.

artículo científico publicado en 1991

The mechanism of antigen presentation by dendritic cells and splenic adherent cells in the induction of an allogeneic cytotoxic T-lymphocyte response to H-2Kk liposomes

artículo científico publicado en 1986

The origins of alloreactivity: differentiation of prekiller cells to viral infection results in alloreactive cytolytic T lymphocytes

artículo científico publicado el 1 de abril de 1980

The regulation of exogenous and endogenous class I MHC genes in a human tumor cell line, K562.

artículo científico publicado en 1990

The role of CD18 in phorbol ester-induced human monocyte-mediated cytotoxicity

artículo científico publicado en 1988

The role of L3T4 (CD4) in T-cell activation

artículo científico publicado en 1987

The role of L3T4 in recognition of Ia by a cytotoxic, H-2Dd-specific T cell hybridoma

artículo científico publicado el 1 de abril de 1984

The role of T cell accessory molecules in the generation of class II-specific xenogeneic cytolytic T cells

artículo científico publicado en 1986

The role of calcineurin in lymphocyte activation

artículo científico publicado en 2000

The role of functional cell surface antigens in T cell activation

artículo científico publicado en 1986

The role of the L3T4 molecule in mitogen and antigen-activated signal transduction

artículo científico publicado en 1987

Three distinct antigens associated with human T-lymphocyte-mediated cytolysis: LFA-1, LFA-2, and LFA-3

artículo científico publicado en 1982

Thy-1 is a differentiation antigen that characterizes immature murine erythroid and myeloid hematopoietic progenitors

artículo científico publicado en 1985

Thymectomized, irradiated, and bone marrow-reconstituted chimeras have normal cytolytic T lymphocyte precursors but a defect in lymphokine production

artículo científico publicado el 1 de mayo de 1984

Transplantation. Antigen, co-stimulators and cytokines: regulators of allogeneic interactions

artículo científico publicado en 1993

Two distinct signal transmission pathways in T lymphocytes are inhibited by complexes formed between an immunophilin and either FK506 or rapamycin

artículo científico publicado en 1990

Two sorting motifs, a ubiquitination motif and a tyrosine motif, are involved in HIV-1 and simian immunodeficiency virus Nef-mediated receptor endocytosis.

artículo científico publicado en 2011

Type-specific reovirus antiserum blocks the cytotoxic T-cell-target cell interaction: evidence for the association of the viral hemagglutinin of a nonenveloped virus with the cell surface

artículo científico publicado en 1981

Tyrosine kinase activity of CD4-associated p56lck may not be required for CD4-dependent T-cell activation

artículo científico publicado en 1993

Tyrosine-phosphorylated Cbl binds to Crk after T cell activation.

artículo científico publicado en 1996

Uncoupling p70(s6) kinase activation and proliferation: rapamycin-resistant proliferation of human CD8(+) T lymphocytes

artículo científico publicado en 2001

Viral restricted cytolytic T lymphocyte recognition of hybrid human-murine class I histocompatibility antigens

scientific article published on 01 April 1986

Wnt-1 and Wnt-4 regulate thymic cellularity

artículo científico publicado en 2002

p56lck association with CD4 is required for the interaction between CD4 and the TCR/CD3 complex and for optimal antigen stimulation

artículo científico publicado en 1992