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Lista de obras de Stephen Dunnett

A Critical Re-Examination of the Intraluminal Filament MCAO Model: Impact of External Carotid Artery Transection

artículo científico publicado en 2011

A Longitudinal Motor Characterisation of the HdhQ111 Mouse Model of Huntington's Disease

artículo científico publicado en 2016

A Longitudinal Operant Assessment of Cognitive and Behavioural Changes in the HdhQ111 Mouse Model of Huntington's Disease

scientific article published on 04 October 2016

A Prospective Pilot Trial for Pallidal Deep Brain Stimulation in Huntington's Disease.

artículo científico publicado en 2015

A combination drug therapy improves cognition and reverses gene expression changes in a mouse model of Huntington's disease.

artículo científico publicado en 2005

A comparative study of preparation techniques for improving the viability of nigral grafts using vital stains, in vitro cultures, and in vivo grafts

artículo científico publicado en 1995

A comparison of the behavioural effects of embryonic nigral grafts in the caudate nucleus and in the putamen of marmosets with unilateral 6-OHDA lesions

artículo científico publicado en 1995

A lateralised grip strength test to evaluate unilateral nigrostriatal lesions in rats ⬇️

artículo científico publicado el 17 de abril de 1998

A novel extended sequence learning task (ESLeT) for rodents: validation and the effects of amphetamine, scopolamine and striatal lesions

artículo científico publicado en 2010

A numerical investigation into the flow field around a worker positioned by an exhaust opening

scientific article published on 01 October 1994

A quantitative study of cell death in the substantia nigra following a mechanical lesion of the medial forebrain bundle

artículo científico publicado en 1995

A role for complement in the rejection of porcine ventral mesencephalic xenografts in a rat model of Parkinson's disease.

artículo científico publicado en 2000

A selective tachykinin receptor agonist promotes differentiation but not survival of rat chromaffin cells in vitro ⬇️

artículo científico publicado el 1 de enero de 1993

A simple breeding protocol for the procurement of accurately staged rat donor embryos for neural transplantation.

artículo científico publicado en 2009

Abnormal synaptic plasticity and impaired spatial cognition in mice transgenic for exon 1 of the human Huntington's disease mutation.

artículo científico publicado en 2000

Acetylcholine-rich neuronal grafts in the forebrain of rats: effects of environmental enrichment, neonatal noradrenaline depletion, host transplantation site and regional source of embryonic donor cells on graft size and acetylcholinesterase-positiv

artículo científico publicado en 1986

Acetylcholine-rich transplants in the hippocampus: influence of intrinsic growth factors and application of nerve growth factor on choline acetyltransferase activity

artículo científico publicado en 1985

Activin A directs striatal projection neuron differentiation of human pluripotent stem cells

artículo científico publicado en 2015

Addition of fresh blood to intrastriatal grafts of embryonic mesencephalon into the hemiparkinsonian rat does not impair the survival of grafted dopaminergic neurones

artículo científico publicado en 1999

Age-dependence of malonate-induced striatal toxicity.

artículo científico publicado en 2000

Age-dependent maintenance of motor control and corticostriatal innervation by death receptor 3.

artículo científico publicado en 2010

Altered mitogen-activated protein kinase signaling, tau hyperphosphorylation and mild spatial learning dysfunction in transgenic rats expressing the beta-amyloid peptide intracellularly in hippocampal and cortical neurons

artículo científico publicado en 2004

Amelioration of non-motor dysfunctions after transplantation of human dopamine neurons in a model of Parkinson's disease

artículo científico publicado en 2016

Amphetamine induced rotation in the assessment of lesions and grafts in the unilateral rat model of Parkinson's disease

artículo científico publicado en 2006

Amphetamine-induced dyskinesia in the transplanted hemi-Parkinsonian mouse.

artículo científico publicado en 2012

Amphetamine-induced rotation in the transplanted hemi-parkinsonian rat – Response to pharmacological modulation ⬇️

artículo científico publicado el 9 de abril de 2012

An investigation of the problem of two-layered immunohistochemical staining in paraformaldehyde fixed sections

artículo científico publicado en 2006

An operant serial implicit learning task (SILT) in rats: task acquisition, performance and the effects of striatal lesions

artículo científico publicado en 2007

Analysis of skilled forelimb movement in rats: the single pellet reaching test and staircase test

artículo científico publicado en 2012

Animal models of Parkinson's disease and L-dopa induced dyskinesia: how close are we to the clinic?

artículo científico publicado en 2007

Antioxidant strategy to counteract the side effects of antipsychotic therapy: an in vivo study in rats

scientific article published on 01 November 2000

Ascorbic acid increases the number of dopamine neurons in vitro and in transplants to the 6-OHDA-lesioned rat brain

artículo científico publicado en 2008

Assessment of Motor Coordination and Balance in Mice Using the Rotarod, Elevated Bridge, and Footprint Tests.

artículo científico publicado en 2012

Assessment of striatal graft viability in the rat in vivo using a small diameter PET scanner

artículo científico publicado en 1995

Assessment of the relationship between pre-chip and post-chip quality measures for Affymetrix GeneChip expression data

artículo científico publicado en 2006

Basic fibroblast growth factor promotes the survival of embryonic ventral mesencephalic dopaminergic neurons--I. Effects in vitro.

artículo científico publicado en 1993

Basic fibroblast growth factor promotes the survival of embryonic ventral mesencephalic dopaminergic neurons--II. Effects on nigral transplants in vivo

scientific article published on 01 September 1993

Basic neural transplantation techniques. I. Dissociated cell suspension grafts of embryonic ventral mesencephalon in the adult rat brain ⬇️

artículo científico publicado el 1 de febrero de 1997

Behavioral analysis of motor and non-motor symptoms in rodent models of Parkinson's disease.

artículo científico publicado en 2010

Behavioral and neurochemical evaluation of a transgenic mouse model of Lesch-Nyhan syndrome

artículo científico publicado en 1988

Behavioral assessment of the ability of intracerebral embryonic neural tissue grafts to ameliorate the effects of brain damage in marmosets

artículo científico publicado en 1994

Behavioral assessment of the effects of embryonic nigral grafts in marmosets with unilateral 6-OHDA lesions of the nigrostriatal pathway.

artículo científico publicado en 1994

Behavioral recovery after transplantation into a rat model of Huntington's disease: dependence on anatomical connectivity and extensive postoperative training

artículo científico publicado en 2000

Behavioural effects of subthalamic nucleus lesions in the hemiparkinsonian marmoset (Callithrix jacchus).

artículo científico publicado en 1998

Behavioural profiles of inbred mouse strains used as transgenic backgrounds. I: motor tests

artículo científico publicado en 2004

Behavioural recovery following striatal transplantation: effects of postoperative training and P-zone volume

artículo científico publicado en 1999

Behavioural recovery following transplantation of substantia nigra in rats subjected to 6-OHDA lesions of the nigrostriatal pathway. I. Unilateral lesions

artículo científico publicado en 1981

Behavioural recovery following transplantation of substantia nigra in rats subjected to 6-OHDA lesions of the nigrostriatal pathway. II. Bilateral lesions

artículo científico publicado en 1981

Behavioural recovery on simple and complex tasks by means of cell replacement therapy in unilateral 6-hydroxydopamine-lesioned mice

artículo científico publicado en 2013

Bilateral striatal lesions disrupt performance in an operant delayed reinforcement task in rats

artículo científico publicado en 2011

Bilateral striatal lesions impair retention of an operant test of short-term memory

artículo científico publicado en 1996

Brain gene expression correlates with changes in behavior in the R6/1 mouse model of Huntington's disease.

artículo científico

Brain repair in a unilateral rat model of Huntington's disease: new insights into impairment and restoration of forelimb movement patterns

artículo científico publicado en 2012

Brain-derived neurotrophic factor (BDNF) overexpression in the forebrain results in learning and memory impairments.

artículo científico publicado en 2008

Bridge grafts of fibroblast growth factor-4-secreting schwannoma cells promote functional axonal regeneration in the nigrostriatal pathway of the adult rat.

artículo científico publicado en 1996

CNS transplantation: structural and functional recovery from brain damage.

artículo científico publicado en 1982

Caspase inhibition increases embryonic striatal graft survival

artículo científico publicado en 2000

Cell therapy for Huntington's disease, the next step forward.

artículo científico publicado en 2002

Cell therapy in Huntington's disease.

artículo científico publicado en 2004

Cell therapy in Parkinson's disease - stop or go?

artículo científico publicado en 2001

Cell transplantation for Huntington's disease

artículo científico publicado en 2006

Cell-based treatments for huntington's disease.

artículo científico

Cellular localisation of somatostatin mRNA and neuropeptide Y mRNA in foetal striatal tissue grafts

artículo científico publicado en 1989

Challenges Facing Quantification of Rat Locomotion along Beams of Varying Widths ⬇️

artículo científico publicado el 1 de noviembre de 2010

Challenges for taking primary and stem cells into clinical neurotransplantation trials for neurodegenerative disease.

artículo científico publicado en 2013

Chapter 55: neural transplantation

artículo científico publicado en 2010

Characterisation of spatial neglect induced by unilateral 6-OHDA lesions on a choice reaction time task in rats.

artículo científico publicado en 2012

Characterization of progressive motor deficits in mice transgenic for the human Huntington's disease mutation.

artículo científico publicado en 1999

Cholecystokinin-dependent regulation of host dopamine inputs to striatal grafts

artículo científico publicado en 1993

Cholinergic grafts, memory and ageing ⬇️

artículo científico publicado el 1 de agosto de 1991

Clinical and genetic characteristics of late-onset Huntington's disease

artículo científico publicado en 2018

Clinical translation of cell transplantation in the brain ⬇️

artículo científico publicado el 1 de diciembre de 2011

Co-expression of MAP-2 and GFAP in cells developing from rat EGF responsive precursor cells

artículo científico publicado en 1997

Cognitive deficits in animal models of basal ganglia disorders.

artículo científico publicado en 2012

Cognitive dysfunction and depression in Parkinson's disease: what can be learned from rodent models?

artículo científico publicado en 2012

Cognitive function. Acetylcholine revisited.

artículo científico publicado en 1995

Cognitive training modifies disease symptoms in a mouse model of Huntington's disease

artículo científico publicado en 2016

Comparative analysis of pathology and behavioural phenotypes in mouse models of Huntington's disease

artículo científico publicado en 2011

Comparison of 6-hydroxydopamine-induced medial forebrain bundle and nigrostriatal terminal lesions in a lateralised nose-poking task in rats

artículo científico publicado en 2004

Comparison of 6-hydroxydopamine-induced medial forebrain bundle and nigrostriatal terminal lesions in rats using a lateralised nose-poking task with low stimulus-response compatibility

artículo científico publicado en 2005

Comparison of 6‐hydroxydopamine lesions of the substantia nigra and the medial forebrain bundle on a lateralised choice reaction time task in mice ⬇️

artículo científico publicado el 1 de noviembre de 2012

Comparison of adrenal and foetal nigral grafts on drug-induced rotation in rats with 6-OHDA lesions

artículo científico publicado en 1989

Comparison of incremental and accelerating protocols of the rotarod test for the assessment of motor deficits in the 6-OHDA model

artículo científico publicado en 2006

Comparison of mHTT Antibodies in Huntington's Disease Mouse Models Reveal Specific Binding Profiles and Steady-State Ubiquitin Levels with Disease Development

artículo científico publicado en 2016

Comparison of rating scales used to evaluate l-DOPA-induced dyskinesia in the 6-OHDA lesioned rat ⬇️

artículo científico publicado el 13 de octubre de 2012

Complement regulatory proteins are expressed at low levels in embryonic human, wild type and transgenic porcine neural tissue

artículo científico publicado en 2004

Conditioned turning in rats: dopaminergic involvement in the initiation of movement rather than the movement itself

artículo científico publicado en 1983

Conditioning versus priming of dopaminergic grafts by amphetamine.

artículo científico publicado en 1993

Context-driven changes in L-DOPA-induced behaviours in the 6-OHDA lesioned rat.

artículo científico publicado en 2011

Controversies in neuroscience

artículo científico publicado en 2002

Correction: Huntingtin Subcellular Localisation Is Regulated by Kinase Signalling Activity in the StHdhQ111 Model of HD

artículo científico publicado en 2016

Corrigendum: Motivational, proteostatic and transcriptional deficits precede synapse loss, gliosis and neurodegeneration in the B6.HttQ111/+ model of Huntington's disease.

artículo científico publicado en 2017

Cross-species neural grafting in a rat model of Parkinson's disease

artículo científico publicado en 1982

Death of dopaminergic neurons in vitro and in nigral grafts: reevaluating the role of caspase activation

artículo científico publicado en 2001

Decreased brown adipose tissue thermogenic activity following a reduction in brain serotonin by intraventricular p-chlorophenylalanine

artículo científico publicado en 1987

Deficits in a lateralized associative learning task in dopamine-depleted rats with functional recovery by dopamine-rich transplants

artículo científico publicado en 2004

Delay-dependent short-term memory deficits in aged rats

artículo científico publicado en 1988

Delayed implantation of nigral grafts improves survival of dopamine neurones and rate of functional recovery.

artículo científico publicado en 1999

Developmentally coordinated extrinsic signals drive human pluripotent stem cell differentiation toward authentic DARPP-32+ medium-sized spiny neurons

artículo científico publicado en 2013

Differential effects of unilateral striatal and nigrostriatal lesions on grip strength, skilled paw reaching and drug-induced rotation in the rat.

artículo científico publicado en 2001

Differential expression of immediate early genes in the hippocampus and spinal cord.

artículo científico publicado en 1990

Differentiation of pluripotent stem cells into striatal projection neurons: a pure MSN fate may not be sufficient

artículo científico publicado en 2014

Direct Comparison of Rat- and Human-Derived Ganglionic Eminence Tissue Grafts on Motor Function.

artículo científico publicado en 2015

Disappearance of the mu-opiate receptor patches in the rat neostriatum following lesioning of the ipsilateral nigrostriatal dopamine pathway with 1-methyl-4-phenylpyridinium ion (MPP+): restoration by embryonic nigral dopamine grafts

artículo científico publicado en 1989

Dissociable roles of the ventral, medial and lateral striatum on the acquisition and performance of a complex visual stimulus-response habit

artículo científico publicado en 1991

Distinct roles for striatal subregions in mediating response processing revealed by focal excitotoxic lesions.

artículo científico publicado en 1999

Do alpha-synuclein vector injections provide a better model of Parkinson's disease than the classic 6-hydroxydopamine model? ⬇️

artículo científico publicado el 15 de junio de 2012

Dopamine and cholecystokinin immunoreactive neurons in mesencephalic grafts reinnervating the neostriatum: evidence for selective growth regulation

artículo científico publicado en 1984

Dopamine cells in nigral grafts differentiate prior to implantation

artículo científico publicado en 1999

Dopamine depletion, stimulation or blockade in the rat disrupts spatial navigation and locomotion dependent upon beacon or distal cues

artículo científico publicado en 1985

Dopamine neuron systems in the brain: an update

artículo científico publicado en 2007

Dopamine-rich grafts alleviate deficits in contralateral response space induced by extensive dopamine depletion in rats.

artículo científico publicado en 2013

Dopamine-rich grafts ameliorate whole body motor asymmetry and sensory neglect but not independent limb use in rats with 6-hydroxydopamine lesions

artículo científico publicado en 1987

Dopamine-rich grafts in the neostriatum and/or nucleus accumbens: effects on drug-induced behaviours and skilled paw-reaching.

artículo científico publicado en 1993

Dopamine-rich transplants in rats with 6-OHDA lesions of the ventral tegmental area. I. Effects on spontaneous and drug-induced locomotor activity

artículo científico publicado en 1984

Dopaminergic grafts implanted into the neonatal or adult striatum: comparative effects on rotation and paw reaching deficits induced by subsequent unilateral nigrostriatal lesions in adulthood

artículo científico publicado en 1993

Dopaminergic neuronal survival and the effects of bFGF in explant, three dimensional and monolayer cultures of embryonic rat ventral mesencephalon

artículo científico publicado en 1995

Double dissociation between hippocampal and prefrontal lesions on an operant delayed matching task and a water maze reference memory task

artículo científico publicado en 2006

Drug repositioning for Alzheimer's disease.

artículo científico publicado en 2012

EGF and FGF-2 responsiveness of rat and mouse neural precursors derived from the embryonic CNS.

artículo científico publicado en 2005

Early onset deficits on the delayed alternation task in the Hdh(Q92) knock-in mouse model of Huntington's disease.

artículo científico publicado en 2011

Effects of Nucleus Basalis Magnocellularis Lesions in Rats on Delayed Matching and Non-Matching to Position Tasks

artículo científico publicado en 1989

Effects of Nucleus Basalis Magnocellularis Lesions in Rats on Delayed Matching and Non-Matching to Position Tasks

scientific article published on 01 January 1990

Effects of STN lesions on simple vs choice reaction time tasks in the rat: preserved motor readiness, but impaired response selection

artículo científico publicado en 2001

Effects of dopamine-rich grafts on conditioned rotation in rats with unilateral 6-hydroxydopamine lesions

artículo científico publicado en 1986

Effects of regional striatal lesions on motor, motivational, and executive aspects of progressive-ratio performance in rats.

artículo científico publicado en 1999

Effects of severity of host striatal damage on the morphological development of intrastriatal transplants in a rodent model of Huntington's disease: implications for timing of surgical intervention.

artículo científico publicado en 1998

Effects of surgical anaesthesia on the viability of nigral grafts in the rat striatum

artículo científico publicado en 1998

Effects of systemic 3-nitropropionic acid-induced lesions of the dorsal striatum on cannabinoid and mu-opioid receptor binding in the basal ganglia.

artículo científico publicado en 2000

Electrophysiological demonstration of host cortical inputs to striatal grafts

artículo científico publicado en 1987

Electrophysiological properties of single units in dopamine-rich mesencephalic transplants in rat brain

artículo científico publicado en 1985

Embryonic donor age and dissection influences striatal graft development and functional integration in a rodent model of Huntington's disease

artículo científico publicado en 2000

Embryonic striatal grafts restore bi-directional synaptic plasticity in a rodent model of Huntington's disease

artículo científico publicado en 2009

Embryonic striatal grafts reverse the disinhibitory effects of ibotenic acid lesions of the ventral striatum.

artículo científico publicado en 1995

Environmental enrichment affects striatal graft morphology and functional recovery.

artículo científico publicado en 2004

Environmental enrichment facilitates long-term potentiation in embryonic striatal grafts.

artículo científico publicado en 2011

Environmental housing and duration of exposure affect striatal graft morphology in a rodent model of Huntington's disease

artículo científico publicado en 2008

Exercise attenuates neuropathology and has greater benefit on cognitive than motor deficits in the R6/1 Huntington's disease mouse model

artículo científico publicado en 2013

Experimental hemiparkinsonism in the rat following chronic unilateral infusion of MPP+ into the nigrostriatal dopamine pathway--III. Reversal by embryonic nigral dopamine grafts

scientific article published on 01 January 1990

Expression of c-fos, jun D and pp60c-src+ mRNAs in the developing and grafted rat striatum

artículo científico publicado en 1996

Fetal porcine dopaminergic cell survival in vitro and its relationship to embryonic age

scientific article published on 01 November 1999

Fetal ventral mesencephalon of human and rat origin maintained in vitro and transplanted to 6-hydroxydopamine-lesioned rats gives rise to grafts rich in dopaminergic neurons.

artículo científico publicado en 1996

Fifty years of dopamine research

artículo científico publicado en 2007

Five choice serial reaction time performance in the HdhQ92 mouse model of Huntington's disease

artículo científico publicado en 2011

Fluorescent histochemical demonstration of catecholamines in brown adipose tissue from obese (ob/ob) and lean mice acclimated at different temperatures

Frontal-striatal disconnection disrupts cognitive performance of the frontal-type in the rat.

artículo científico publicado en 2005

Fronto-striatal disconnection disrupts operant delayed alternation performance in the rat.

artículo científico publicado en 2006

Function recovery following neural transplantation of embryonic septal nuclei in adult rats with septohippocampal lesions

artículo científico publicado en 1982

Functional and anatomical reconstruction of the 6-hydroxydopamine lesioned nigrostriatal system of the adult rat.

artículo científico publicado en 1996

Functional correlates of compensatory collateral sprouting by aminergic and cholinergic afferents in the hippocampal formation

artículo científico publicado en 1983

Functional integration of neural grafts in Parkinson's disease

artículo científico publicado en 1999

Functional integration of striatal allografts in a primate model of Huntington's disease.

artículo científico publicado en 1998

Functional neural transplantation III. Primary and stem cell therapies for brain repair, part I. Introduction

artículo científico publicado en 2012

Gene expression and behaviour in mouse models of HD.

artículo científico publicado en 2011

Gene expression in striatal grafts--I. Cellular localization of neurotransmitter mRNAs

artículo científico publicado en 1990

Generating Excitotoxic Lesion Models of Huntington’s Disease

artículo científico publicado en 2018

Genetic, temporal and diurnal influences on L-dopa-induced dyskinesia in the 6-OHDA model

artículo científico publicado en 2008

Graft-derived recovery from 6-OHDA lesions: specificity of ventral mesencephalic graft tissues

artículo científico publicado en 1988

Grafts of embryonic substantia nigra reinnervating the ventrolateral striatum ameliorate sensorimotor impairments and akinesia in rats with 6-OHDA lesions of the nigrostriatal pathway

artículo científico publicado en 1981

HSV vector-delivery of GDNF in a rat model of PD: partial efficacy obscured by vector toxicity

artículo científico publicado en 2004

Hippocampal lesions impair performance on a conditional delayed matching and non-matching to position task in the rat.

artículo científico publicado en 2006

Human Pluripotent Stem Cell-Derived Striatal Interneurons: Differentiation and Maturation In Vitro and in the Rat Brain

artículo científico publicado en 2019

Human stem cells for CNS repair.

artículo científico publicado en 2007

Huntingtin Subcellular Localisation Is Regulated by Kinase Signalling Activity in the StHdhQ111 Model of HD.

artículo científico publicado en 2015

Hypersensitivity to alpha-methyl-p-tyrosine suggests that behavioural recovery of rats receiving neonatal 6-OHDA lesions is mediated by residual catecholamine neurones

artículo científico publicado en 1989

Ibotenic acid lesions of the lateral hypothalamus: comparison with 6-hydroxydopamine-induced sensorimotor deficits

artículo científico publicado en 1985

Ibotenic acid lesions of the lateral hypothalamus: comparison with the electrolytic lesion syndrome

artículo científico publicado en 1984

Ibotenic acid lesions of the striatum reduce drug-induced rotation in the 6-hydroxydopamine-lesioned rat

scientific article published on 01 January 1994

Identification of novel alternative splicing events in the huntingtin gene and assessment of the functional consequences using structural protein homology modelling.

artículo científico publicado en 2014

Immortalized neural cells from trisomy 16 mice as models for Alzheimer's disease.

artículo científico publicado en 1996

Immunohistochemical identification of rat adrenal cortical tissue in situ, in vitro, and in intracerebral adrenal grafts

artículo científico publicado en 1993

Impact factor rises again

scientific article published on 01 December 2004

Impaired bidirectional synaptic plasticity and procedural memory formation in striatum-specific cAMP response element-binding protein-deficient mice.

artículo científico publicado en 2006

Impaired sensitivity to Pavlovian stimulus-outcome learning after excitotoxic lesion of the ventrolateral neostriatum

artículo científico publicado en 2011

Improved survival of young donor age dopamine grafts in a rat model of Parkinson's disease.

artículo científico publicado en 2007

In vivo effects of kFGF on embryonic nigral grafts in a rat model of Parkinson's disease.

artículo científico publicado en 1995

In vivo measurement of spontaneous release and metabolism of dopamine from intrastriatal nigral grafts using intracerebral dialysis

artículo científico publicado en 1986

In vivo transgene expression from an adenoviral vector is altered following a 6-OHDA lesion of the dopamine system.

artículo científico publicado en 2005

Increased efficacy of the 6-hydroxydopamine lesion of the median forebrain bundle in small rats, by modification of the stereotaxic coordinates.

artículo científico publicado en 2011

Increased proenkephalin mRNA levels in the rat neostriatum following lesion of the ipsilateral nigrostriatal dopamine pathway with 1-methyl-4-phenylpyridinium ion (MPP+): reversal by embryonic nigral dopamine grafts

artículo científico publicado en 1991

Increased survival of rat EGF-generated CNS precursor cells using B27 supplemented medium

scientific article published on 01 January 1995

Influence of chronic L-DOPA treatment on immune response following allogeneic and xenogeneic graft in a rat model of Parkinson's disease ⬇️

artículo científico publicado en 2016

Interactions between meningeal cells and astrocytes in vivo and in vitro ⬇️

artículo científico publicado el 24 de abril de 1991

Intracerebral grafting of embryonic neural cells into the adult host brain: an overview of the cell suspension method and its application.

artículo científico publicado en 1983

Intraspinal stem cell transplantation for amyotrophic lateral sclerosis: Ready for efficacy clinical trials?

artículo científico publicado en 2016

Intrastriatal dopamine-rich grafts induce a hyperexpression of Fos protein when challenged with amphetamine

artículo científico publicado en 1992

Intrastriatal grafts derived from fetal striatal primordia--IV. Host and donor neurons are not intermixed

artículo científico publicado en 1993

Introduction (Part II).

artículo científico publicado en 2012

Is the adult mouse striatum a hostile host for neural transplant survival?

artículo científico publicado en 2013

Is there a place for human fetal-derived stem cells for cell replacement therapy in Huntington's disease?

artículo científico publicado en 2017

Ivan Divac and the neostriatum as a cognitive structure

artículo científico publicado en 1999

L-DOPA, dyskinesia and striatal plasticity ⬇️

artículo científico publicado el 1 de mayo de 2003

Latency associated promoter transgene expression in the central nervous system after stereotaxic delivery of replication-defective HSV-1-based vectors

artículo científico publicado en 2001

Lentivector-mediated delivery of GDNF protects complex motor functions relevant to human Parkinsonism in a rat lesion model.

artículo científico publicado en 2005

Lesions of the dorsomedial striatum impair formation of attentional set in rats.

artículo científico publicado en 2013

Lesions of the premotor and supplementary motor areas fail to prevent implicit learning in the operant serial implicit learning task

artículo científico publicado en 2009

Lickometry: A novel and sensitive method for assessing functional deficits in rats after stroke.

artículo científico publicado en 2016

Light and electron microscopic characterization of the evolution of cellular pathology in HdhQ92 Huntington's disease knock-in mice.

artículo científico publicado en 2011

Light and electron microscopic characterization of the evolution of cellular pathology in YAC128 Huntington's disease transgenic mice

artículo científico publicado en 2011

Light and electron microscopic characterization of the evolution of cellular pathology in the Hdh(CAG)150 Huntington's disease knock-in mouse.

artículo científico publicado en 2011

Light and electron microscopic characterization of the evolution of cellular pathology in the R6/1 Huntington's disease transgenic mice.

artículo científico publicado en 2011

Localization of the mRNAs for the short and long isoforms of the dopamine D2 receptor in embryonic striatal grafts: predominance of the short isoform

scientific article published on 01 December 1994

Long-term expansion of human foetal neural progenitors leads to reduced graft viability in the neonatal rat brain

artículo científico publicado en 2012

Long-term hibernation of human fetal striatal tissue does not adversely affect its differentiation in vitro or graft survival: implications for clinical trials in Huntington's disease.

artículo científico publicado en 2003

Long-term restorative effects of bromocriptine on operant responding in the 6-hydroxydopamine-lesioned rat.

artículo científico publicado en 2013

Long-term survival of human central nervous system progenitor cells transplanted into a rat model of Parkinson's disease.

artículo científico publicado en 1997

Longitudinal analyses of operant performance on the serial implicit learning task (SILT) in the YAC128 Huntington's disease mouse line

artículo científico publicado en 2011

Longitudinal analysis of gene expression and behaviour in the HdhQ150 mouse model of Huntington's disease

artículo científico publicado en 2011

Longitudinal analysis of the behavioural phenotype in Hdh(CAG)150 Huntington's disease knock-in mice

artículo científico publicado en 2010

Longitudinal analysis of the behavioural phenotype in HdhQ92 Huntington's disease knock-in mice

artículo científico publicado en 2010

Longitudinal analysis of the behavioural phenotype in R6/1 (C57BL/6J) Huntington's disease transgenic mice

artículo científico publicado en 2011

Longitudinal analysis of the behavioural phenotype in YAC128 (C57BL/6J) Huntington's disease transgenic mice

artículo científico publicado en 2010

Mechanisms and use of neural transplants for brain repair

artículo científico publicado en 2017

Medial prefrontal and neostriatal lesions disrupt performance in an operant delayed alternation task in rats

artículo científico publicado en 1999

Medical terminations of pregnancy: a viable source of tissue for cell replacement therapy for neurodegenerative disorders.

artículo científico publicado en 2011

Medium spiny neurons for transplantation in Huntington's disease

artículo científico publicado en 2009

Membrane permeability coefficients of murine primary neural brain cells in the presence of cryoprotectant.

artículo científico publicado en 2009

Microfluidic chip-based synthesis of alginate microspheres for encapsulation of immortalized human cells

artículo científico publicado en 2007

Mitogenic effect of basic fibroblast growth factor on embryonic ventral mesencephalic dopaminergic neurone precursors

artículo científico publicado en 1993

Monoamine deficiency in a transgenic (Hprt-) mouse model of Lesch-Nyhan syndrome

artículo científico publicado en 1989

Monoclonal antibody G10 against microtubule-associated protein 1x distinguishes between growing and regenerating axons

artículo científico publicado en 1989

Morphological and cellular changes within embryonic striatal grafts associated with enriched environment and involuntary exercise.

artículo científico publicado en 2006

Motivational, proteostatic and transcriptional deficits precede synapse loss, gliosis and neurodegeneration in the B6.HttQ111/+ model of Huntington's disease

artículo científico publicado en 2017

Motor Assessment in Huntington's Disease Mice

artículo científico publicado en 2018

Motor coordination and balance in rodents

scientific article published on 01 August 2001

Motor training effects on recovery of function after striatal lesions and striatal grafts.

artículo científico publicado en 2003

Mouse Models of Huntington's Disease

artículo científico publicado en 2015

Movement without dopamine: striatal dopamine is required to maintain but not to perform learned actions

artículo científico publicado en 2007

Mutant huntingtin's effects on striatal gene expression in mice recapitulate changes observed in human Huntington's disease brain and do not differ with mutant huntingtin length or wild-type huntingtin dosage

artículo científico publicado en 2007

Myelination and behaviour of tenascin-C null transgenic mice

artículo científico publicado en 1999

Neonatal desensitization allows long-term survival of neural xenotransplants without immunosuppression.

artículo científico publicado en 2009

Neonatal dopamine-rich grafts and 6-OHDA lesions independently provide partial protection from the adult nigrostriatal lesion syndrome

artículo científico publicado en 1989

Neural Stem Cell Technology as a Novel Treatment for Parkinson's Disease ⬇️

artículo científico publicado el 1 de enero de 2001

Neural Transplantation in Animal Models of Dementia.

artículo científico publicado en 1990

Neural cells from primary human striatal xenografts migrate extensively in the adult rat CNS.

artículo científico publicado en 2002

Neural grafting in Parkinson's disease unraveling the mechanisms underlying graft-induced dyskinesia

artículo científico publicado en 2010

Neural tissue transplantation, repair, and rehabilitation

artículo científico publicado el 1 de enero de 2013

Neural transplantation for the treatment of Parkinson's disease

artículo científico publicado en 2003

Neural transplantation: restoring complex circuitry in the striatum.

artículo científico publicado en 2001

Neuronal cell transplantation for Parkinson's and Huntington's diseases

artículo científico publicado en 1997

Neurorehabilitation with neural transplantation.

artículo científico publicado en 2010

Neurotoxic amino acid lesions of the lateral hypothalamus: a parametric comparison of the effects of ibotenate, N-methyl-D,L-aspartate and quisqualate in the rat.

artículo científico publicado en 1985

Neurotoxic lesions of ventrolateral but not anteromedial neostriatum in rats impair differential reinforcement of low rates (DRL) performance

artículo científico publicado en 1982

Nigral 6-hydroxydopamine lesion impairs performance in a lateralised choice reaction time task--impact of training and task parameters

artículo científico publicado en 2014

Nigral grafts in animal models of Parkinson's disease. Is recovery beyond motor function possible?

artículo científico publicado el 1 de enero de 2012

Nigral grafts in neonatal rats protect from aphagia induced by subsequent adult 6-OHDA lesions: the importance of striatal location

scientific article published on 01 January 1990

Nimodipine enhances growth and vascularization of neural grafts

artículo científico publicado en 1989

Observing Huntington's Disease: the European Huntington's Disease Network's REGISTRY

artículo científico publicado en 2010

Operant Analysis of Fronto-striatal Function in Rodents

Operant-based instrumental learning for analysis of genetically modified models of Huntington's disease.

scientific article published on 24 March 2011

Optimising Golgi-Cox staining for use with perfusion-fixed brain tissue validated in the zQ175 mouse model of Huntington's disease

artículo científico publicado en 2015

Optimising plasticity: environmental and training associated factors in transplant-mediated brain repair.

artículo científico publicado en 2005

Outcome of cell suspension allografts in a patient with Huntington's disease

artículo científico publicado en 2018

Pharmacological modulation of amphetamine-induced dyskinesia in transplanted hemi-parkinsonian rats.

artículo científico publicado en 2012

Phosphorylation of Parkin at serine 65 is essential for its activation

artículo científico publicado en 2018

Porcine neural xenografts in the immunocompetent rat: immune response following grafting of expanded neural precursor cells

artículo científico publicado en 2001

Potential cellular and regenerative approaches for the treatment of Parkinson's disease.

artículo científico publicado en 2008

Pre-treatment with dopamine agonists influence L-dopa mediated rotations without affecting abnormal involuntary movements in the 6-OHDA lesioned rat.

artículo científico publicado en 2010

Predictive Markers Guide Differentiation to Improve Graft Outcome in Clinical Translation of hESC-Based Therapy for Parkinson's Disease

artículo científico publicado en 2016

Preface

Preface

Preface

Proactive interference effects on short-term memory in rats: I. Basic parameters and drug effects

artículo científico publicado en 1990

Proactive interference effects on short-term memory in rats: II. Effects in young and aged rats

artículo científico publicado en 1990

Profiles of motor and cognitive impairment in the transgenic rat model of Huntington's disease.

artículo científico publicado en 2011

Progressive striatal and cortical dopamine receptor dysfunction in Huntington's disease: a PET study.

artículo científico publicado en 2003

Prospects for new restorative and neuroprotective treatments in Parkinson's disease

artículo científico publicado en 1999

Proteomic changes in the brains of Huntington's disease mouse models reflect pathology and implicate mitochondrial changes

artículo científico publicado en 2011

Proximal movements compensate for distal forelimb movement impairments in a reach-to-eat task in Huntington's disease: new insights into motor impairments in a real-world skill

artículo científico publicado en 2010

Re-examining the ontogeny of substantia nigra dopamine neurons

artículo científico publicado en 2006

Recovery of functional deficits following early donor age ventral mesencephalic grafts in a rat model of Parkinson's disease.

artículo científico publicado en 2008

Regulatory impairments following selective 6-OHDA lesions of the neostriatum

artículo científico publicado en 1982

Regulatory impairments following selective kainic acid lesions of the neostriatum

artículo científico publicado en 1980

Rehabilitation training in neural restitution.

artículo científico

Reinnervation of the denervated striatum by substantia nigra transplants: functional consequences as revealed by pharmacological and sensorimotor testing

artículo científico publicado en 1980

Repair of the damaged brain. The Alfred Meyer Memorial Lecture 1998.

artículo científico publicado en 1999

Reprogramming the diseased brain.

artículo científico publicado en 2017

Response disinhibition on a delayed matching to position task induced by amphetamine, nicotine and age

artículo científico publicado en 1991

Reverse transcription of inserted DNA in a monkey gives us ANDi.

artículo científico publicado en 2001

Rewiring the Parkinsonian brain

scientific article published on 01 February 2002

Role of corticostriatal and nigrostriatal inputs in malonate-induced striatal toxicity.

artículo científico publicado en 2001

Rule learning, visuospatial function and motor performance in the Hdh(Q92) knock-in mouse model of Huntington's disease.

artículo científico

SMAD transcription factors are altered in cell models of HD and regulate HTT expression

artículo científico publicado en 2016

Selective cognitive impairment in the YAC128 Huntington's disease mouse.

artículo científico publicado en 2011

Selective discrimination learning impairments in mice expressing the human Huntington's disease mutation.

artículo científico publicado en 1999

Selective extra-dimensional set shifting deficit in a knock-in mouse model of Huntington's disease

scientific journal article

Selective immunolesioning of the basal forebrain cholinergic system disrupts short-term memory in rats.

artículo científico publicado en 1996

Selective lesioning of the cholinergic septo-hippocampal pathway does not disrupt spatial short-term memory: a comparison with the effects of fimbria-fornix lesions

artículo científico publicado en 2004

Sensorimotor impairments following localized kainic acid and 6-hydroxydopamine lesions of the neostriatum

artículo científico publicado en 1982

Septal transplants restore maze learning in rats with fornix-fimbria lesions

artículo científico publicado en 1982

Serotonin hyperinnervation after foetal nigra or raphe transplantation in the neostriatum of adult rats

artículo científico publicado en 1991

Sex and gender in Brain Research Bulletin ⬇️

artículo científico publicado el 15 de mayo de 2003

Similar striatal gene expression profiles in the striatum of the YAC128 and HdhQ150 mouse models of Huntington's disease are not reflected in mutant Huntingtin inclusion prevalence

artículo científico publicado en 2015

Spatial learning and motor deficits in aged rats

artículo científico publicado en 1984

Spatially and temporally restricted chemoattractive and chemorepulsive cues direct the formation of the nigro-striatal circuit

artículo científico publicado en 2004

Special Issue: Trophic Factors, Neural Growth, and Transplantation in the CNS

artículo científico publicado en 1996

Spontaneous and drug-induced rotation following localized 6-hydroxydopamine and kainic acid-induced lesions of the neostriatum

artículo científico publicado en 1982

Stem cell transplantation for Huntington's disease.

artículo científico publicado en 2007

Striatal graft projections are influenced by donor cell type and not the immunogenic background.

artículo científico publicado en 2007

Striatal grafts alleviate bilateral striatal lesion deficits in operant delayed alternation in the rat.

artículo científico publicado en 2006

Striatal grafts alleviate deficits in response execution in a lateralised reaction time task.

artículo científico publicado en 1998

Striatal grafts in rats with unilateral neostriatal lesions--I. Ultrastructural evidence of afferent synaptic inputs from the host nigrostriatal pathway

artículo científico publicado en 1988

Striatal grafts in rats with unilateral neostriatal lesions--III. Recovery from dopamine-dependent motor asymmetry and deficits in skilled paw reaching

artículo científico publicado en 1988

Striatal lesions in the mouse disrupt acquisition and retention, but not implicit learning, in the SILT procedural motor learning task

artículo científico publicado en 2007

Striatal lesions produce distinctive impairments in reaction time performance in two different operant chambers

artículo científico publicado en 1998

Striatal neurons in striatal grafts are derived from both post-mitotic cells and dividing progenitors

artículo científico publicado en 2004

Striatal transplantation in a transgenic mouse model of Huntington's disease

artículo científico publicado en 1998

Subthalamic nucleus lesions induce deficits as well as benefits in the hemiparkinsonian rat.

artículo científico publicado en 1999

Subtle but progressive cognitive deficits in the female tgHD hemizygote rat as demonstrated by operant SILT performance.

artículo científico publicado en 2009

Surveying the literature from animal experiments.

artículo científico publicado en 2005

Survival and differentiation of rat and human epidermal growth factor-responsive precursor cells following grafting into the lesioned adult central nervous system

artículo científico publicado en 1996

Survival and functional restoration of human fetal ventral mesencephalon following transplantation in a rat model of Parkinson's disease

artículo científico publicado en 2012

Survival of nigral grafts within the striatum of marmosets with 6-OHDA lesions depends critically on donor embryo age.

artículo científico publicado en 1997

Synaptic input and local output of dopaminergic neurons in grafts that functionally reinnervate the host neostriatum

artículo científico publicado en 1987

Synaptic relationships between cortical and dopaminergic inputs and intrinsic GABAergic systems within intrastriatal striatal grafts

artículo científico publicado en 1993

Systematic and detailed analysis of behavioural tests in the rat middle cerebral artery occlusion model of stroke: Tests for long-term assessment.

artículo científico publicado en 2016

Targeting delivery in Parkinson's disease

artículo científico publicado en 2016

Targeting the subthalamic nucleus in the treatment of Parkinson's disease

artículo científico publicado en 1998

Technical factors that influence neural transplant safety in Huntington's disease.

artículo científico publicado en 2010

Tests to assess motor phenotype in mice: a user's guide

artículo científico publicado en 2009

The "staircase test": a measure of independent forelimb reaching and grasping abilities in rats

artículo científico publicado en 1991

The 12th International Symposium on Neural Transplantation and Restoration

artículo científico publicado en 2013

The 6-OHDA mouse model of Parkinson's disease - Terminal striatal lesions provide a superior measure of neuronal loss and replacement than median forebrain bundle lesions

artículo científico publicado en 2015

The Amphetamine Induced Rotation Test: A Re-Assessment of Its Use as a Tool to Monitor Motor Impairment and Functional Recovery in Rodent Models of Parkinson's Disease

artículo científico publicado en 2019

The Corridor Task: a simple test of lateralised response selection sensitive to unilateral dopamine deafferentation and graft-derived dopamine replacement in the striatum.

artículo científico publicado en 2005

The Effect of Tissue Preparation and Donor Age on Striatal Graft Morphology in the Mouse.

artículo científico publicado en 2018

The T cell oncogene Tal2 is necessary for normal development of the mouse brain

scientific journal article

The biology and behaviour of intracerebral adrenal transplants in animals and man.

artículo científico publicado en 1993

The contributions of motor cortex, nigrostriatal dopamine and caudate-putamen to skilled forelimb use in the rat.

artículo científico publicado en 1986

The corridor task: striatal lesion effects and graft-mediated recovery in a model of Huntington's disease

artículo científico publicado en 2007

The development of intracerebral cell-suspension implants is influenced by the grafting medium.

artículo científico publicado en 1998

The effect of additional noradrenergic and serotonergic depletion on a lateralised choice reaction time task in rats with nigral 6-OHDA lesions

artículo científico publicado en 2013

The effect of microglia on embryonic dopaminergic neuronal survival in vitro: diffusible signals from neurons and glia change microglia from neurotoxic to neuroprotective.

artículo científico publicado en 1999

The effects of bilateral striatal lesions on the acquisition of an operant test of short term memory.

artículo científico publicado en 1995

The effects of donor stage on the survival and function of embryonic striatal grafts in the adult rat brain. I. Morphological characteristics

artículo científico publicado en 1997

The effects of donor stage on the survival and function of embryonic striatal grafts in the adult rat brain. II. Correlation between positron emission tomography and reaching behaviour.

artículo científico publicado en 1997

The effects of excitotoxic lesions of the nucleus accumbens on a matching to position task

artículo científico publicado en 1991

The effects of lateralized training on spontaneous forelimb preference, lesion deficits, and graft-mediated functional recovery after unilateral striatal lesions in rats.

artículo científico publicado en 2006

The expression of Huntingtin-associated protein (HAP1) mRNA in developing, adult and ageing rat CNS: implications for Huntington's disease neuropathology

artículo científico publicado en 1998

The failure of axon regeneration in the CNS is not absolute.

artículo científico publicado en 1999

The influence of environment and experience on neural grafts.

artículo científico publicado en 2001

The influence of excitotoxic basal ganglia lesions on motor performance in the common marmoset.

artículo científico publicado en 2000

The intrinsic specification of gamma-aminobutyric acid type A receptor alpha6 subunit gene expression in cerebellar granule cells

artículo científico publicado en 1999

The lateral neostriatum is necessary for compensatory ingestive behaviour after intravascular dehydration in female rats.

artículo científico publicado en 2013

The localization of an antibody to STEP in embryonic striatal tissue grafts

artículo científico publicado en 1994

The localization of cholecystokinin mRNA in embryonic striatal tissue grafts: further evidence for the presence of non-striatal cells.

artículo científico publicado en 1993

The long-term safety and efficacy of bilateral transplantation of human fetal striatal tissue in patients with mild to moderate Huntington's disease

artículo científico publicado en 2013

The morphological development of neurons derived from EGF- and FGF-2-driven human CNS precursors depends on their site of integration in the neonatal rat brain

artículo científico publicado en 2000

The neurotrophin NT4/5, but not NT3, enhances the efficacy of nigral grafts in a rat model of Parkinson's disease

artículo científico publicado en 1996

The placement of a striatal ibotenic acid lesion affects skilled forelimb use and the direction of drug-induced rotation

artículo científico publicado en 1996

The potential for circuit reconstruction by expanded neural precursor cells explored through porcine xenografts in a rat model of Parkinson's disease

artículo científico publicado en 2002

The problem of antipsychotic treatment for functional imaging in Huntington's disease: receptor binding, gene expression and locomotor activity after sub-chronic administration and wash-out of haloperidol in the rat.

artículo científico publicado en 2000

The release of excitatory amino acids, dopamine, and potassium following transplantation of embryonic mesencephalic dopaminergic grafts to the rat striatum, and their effects on dopaminergic neuronal survival in vitro

artículo científico publicado en 2002

The search for genetic mouse models of prodromal Parkinson's disease.

artículo científico publicado en 2012

The staircase test of skilled reaching in mice

artículo científico publicado en 2001

The survival of neural precursor cell grafts is influenced by in vitro expansion.

artículo científico publicado en 2005

The use of rodent skilled reaching as a translational model for investigating brain damage and disease.

artículo científico

The utilisation of operant delayed matching and non-matching to position for probing cognitive flexibility and working memory in mouse models of Huntington's disease

artículo científico publicado en 2015

Three-dimensional motion analysis of postural adjustments during over-ground locomotion in a rat model of Parkinson's disease

artículo científico publicado en 2011

Time course of choice reaction time deficits in the Hdh(Q92) knock-in mouse model of Huntington's disease in the operant serial implicit learning task (SILT).

artículo científico publicado en 2008

Tissue transplants for PD.

artículo científico publicado en 1994

Towards a protocol for the preparation and delivery of striatal tissue for clinical trials of transplantation in Huntington's disease.

artículo científico publicado en 2000

Training specificity, graft development and graft-mediated functional recovery in a rodent model of Huntington's disease.

artículo científico publicado en 2005

Translation of cell therapies to the clinic: characteristics of cell suspensions in large-diameter injection cannulae

artículo científico publicado en 2014

Transplantation in the rat model of Parkinson's disease: ectopic versus homotopic graft placement.

artículo científico publicado en 2000

Transplantation of embryonic dopamine neurons: what we know from rats ⬇️

artículo científico publicado el 1 de abril de 1991

Transplantation of expanded neural precursor cells from the developing pig ventral mesencephalon in a rat model of Parkinson's disease

artículo científico publicado en 2003

Transplantation site influences the phenotypic differentiation of dopamine neurons in ventral mesencephalic grafts in Parkinsonian rats

artículo científico publicado en 2017

Transplanted dopaminergic neurons: more or less?

artículo científico publicado en 2001

Transplanted hNT cells ("LBS neurons") in a rat model of huntington's disease: good survival, incomplete differentiation, and limited functional recovery.

artículo científico publicado en 2004

Trophic mechanisms are not enough

scientific article published on 01 July 1989

Ultrastructural neuropathology in murine trisomy 16 hippocampal grafts.

artículo científico publicado en 1993

Unilateral 6-OHDA lesions induce lateralised deficits in a 'skinner box' operant choice reaction time task in rats

artículo científico publicado en 2012

Unilateral dopamine lesions in neonatal, weanling and adult rats: comparison of rotation and reaching deficits.

artículo científico publicado en 1992

Unilateral lesions of the dorsal striatum in rats disrupt responding in egocentric space

artículo científico publicado en 1997

Unilateral lesions of the medial agranular cortex impair responding on a lateralised reaction time task.

artículo científico publicado en 2000

Unilateral nigrostriatal 6-hydroxydopamine lesions in mice II: Predicting l-DOPA-induced dyskinesia ⬇️

artículo científico publicado el 19 de septiembre de 2011

Unilateral striatal lesions impair response execution on a lateralised choice reaction time task.

artículo científico publicado en 1997

Using Actiwatch to monitor circadian rhythm disturbance in Huntington' disease: A cautionary note

artículo científico publicado en 2016

Validating the use of M4-BAC-GFP mice as tissue donors in cell replacement therapies in a rodent model of Huntington's disease

artículo científico publicado en 2011

Validation of the l-dopa-induced dyskinesia in the 6-OHDA model and evaluation of the effects of selective dopamine receptor agonists and antagonists

artículo científico publicado en 2004

What helps can also hinder: A dissociation in the acute effect of levodopa treatment on motor and cognitive functions

artículo científico publicado en 2013

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