Lista de obras -

4Beta-hydroxycholesterol is a new endogenous CYP3A marker: relationship to CYP3A5 genotype, quinine 3-hydroxylation and sex in Koreans, Swedes and Tanzanians

artículo científico publicado en 2008

4beta-hydroxycholesterol as an endogenous marker for CYP3A4/5 activity. Stability and half-life of elimination after induction with rifampicin

artículo científico publicado en 2008

4β-Hydroxycholesterol, an endogenous marker of CYP3A4/5 activity in humans

artículo científico publicado en 2011

A common novel CYP2C19 gene variant causes ultrarapid drug metabolism relevant for the drug response to proton pump inhibitors and antidepressants

artículo científico publicado en 2006

Allele-specific expression and gene methylation in the control of CYP1A2 mRNA level in human livers

artículo científico publicado en 2009

Alprazolam as a probe for CYP3A using a single blood sample: pharmacokinetics of parent drug, and of alpha- and 4-hydroxy metabolites in healthy subjects

artículo científico publicado en 2005

Amodiaquine, its desethylated metabolite, or both, inhibit the metabolism of debrisoquine (CYP2D6) and losartan (CYP2C9) in vivo

CYP2C19 activity comparison between Swedes and Koreans: effect of genotype, sex, oral contraceptive use, and smoking

article by Margareta Ramsjö et al published 25 May 2010 in European Journal of Clinical Pharmacology

CYP2D6 genotype in relation to perphenazine concentration and pituitary pharmacodynamic tissue sensitivity in Asians: CYP2D6-serotonin-dopamine crosstalk revisited.

artículo científico publicado en 2007

CYP2D6 is a major determinant of metoprolol disposition and effects in hospitalized Russian patients treated for acute myocardial infarction

artículo científico publicado en 2008

CYP2D6, serotonin and suicide

artículo científico publicado en 2010

CYP3A5 genotype has significant effect on quinine 3-hydroxylation in Tanzanians, who have lower total CYP3A activity than a Swedish population

artículo científico publicado en 2006

Carriers of the UGT1A4 142T>G gene variant are predisposed to reduced olanzapine exposure--an impact similar to male gender or smoking in schizophrenic patients

artículo científico publicado en 2010

Comparison of endogenous 4β-hydroxycholesterol with midazolam as markers for CYP3A4 induction by rifampicin

artículo científico publicado en 2013

Comparison ofN-Acetyltransferase-2 Enzyme Genotype-Phenotype and Xanthine Oxidase Enzyme Activity Between Swedes and Koreans

Comparisons of CYP1A2 genetic polymorphisms, enzyme activity and the genotype-phenotype relationship in Swedes and Koreans

article

Cytochrome P450 3A activity in mothers and their neonates as determined by plasma 4β-hydroxycholesterol

artículo científico publicado en 2011

Decreased Activity and Genetic Polymorphisms of CYP2C19 in Behçet's Disease.

artículo científico publicado en 2017

Differences in CYP2C9 Genotype and Enzyme Activity Between Swedes and Koreans of Relevance for Personalized Medicine: Role of Ethnicity, Genotype, Smoking, Age, and Sex

scholarly article by Fazleen H.M. Hatta published in June 2015

Dose of proton pump inhibitors and the CYP2C19 genotype

artículo científico publicado en 2004

Effect of SLCO1B1 polymorphism on induction of CYP3A4 by rifampicin

article by Mikko Niemi et al published August 2006 in Pharmacogenetics and Genomics

Effects of caffeine intake on the pharmacokinetics of melatonin, a probe drug for CYP1A2 activity ⬇️

artículo científico publicado el 1 de diciembre de 2003

Evidence for environmental influence on CYP2D6-catalysed debrisoquine hydroxylation as demonstrated by phenotyping and genotyping of Ethiopians living in Ethiopia or in Sweden

artículo científico publicado en 2002

Fluconazole-induced intoxication with phenytoin in a patient with ultra-high activity of CYP2C9.

artículo científico publicado en 2010

Genetic and Clinical Factors Affecting Plasma Clozapine Concentration

artículo científico publicado en 2015

Genetic polymorphism of CYP1A2 in Ethiopians affecting induction and expression: characterization of novel haplotypes with single-nucleotide polymorphisms in intron 1.

artículo científico publicado en 2003

Geographical/interracial differences in polymorphic drug oxidation. Current state of knowledge of cytochromes P450 (CYP) 2D6 and 2C19

artículo científico publicado en 1995

High CYP2A6 enzyme activity as measured by a caffeine test and unique distribution of CYP2A6 variant alleles in Ethiopian population

artículo científico publicado en 2013

Importance of ethnicity, CYP2B6 and ABCB1 genotype for efavirenz pharmacokinetics and treatment outcomes: a parallel-group prospective cohort study in two sub-Saharan Africa populations

artículo científico publicado en 2013

Increased omeprazole metabolism in carriers of the CYP2C19*17 allele; a pharmacokinetic study in healthy volunteers

artículo científico publicado en 2008

Induction of CYP1A2 by heavy coffee consumption in Serbs and Swedes

article by Natasa Djordjevic et al published 22 December 2007 in European Journal of Clinical Pharmacology

Inflammation down-regulates CYP3A4-catalysed drug metabolism in hemodialysis patients.

artículo científico publicado en 2018

Influence of the CYP2D6 polymorphism and hemodialysis on codeine disposition in patients with end-stage renal disease

artículo científico publicado en 2009

Inhibition of metoprolol metabolism and potentiation of its effects by paroxetine in routinely treated patients with acute myocardial infarction (AMI).

artículo científico publicado en 2007

Interferon-beta treatment in patients with multiple sclerosis does not alter CYP2C19 or CYP2D6 activity

artículo científico publicado en 2003

Is there a need to increase the dose of efavirenz during concomitant rifampicin-based antituberculosis therapy in sub-Saharan Africa? The HIV-TB pharmagene study

artículo científico publicado en 2015

Kinetics of omeprazole and escitalopram in relation to the CYP2C19*17 allele in healthy subjects

artículo científico publicado en 2008

Long-Term Effect of Rifampicin-Based Anti-TB Regimen Coadministration on the Pharmacokinetic Parameters of Efavirenz and 8-Hydroxy-Efavirenz in Ethiopian Patients

artículo científico publicado en 2016

Long-term efavirenz pharmacokinetics is comparable between Tanzanian HIV and HIV/Tuberculosis patients with the same CYP2B6*6 genotype

artículo científico publicado en 2018

Low daily 10-mg and 20-mg doses of fluvoxamine inhibit the metabolism of both caffeine (cytochrome P4501A2) and omeprazole (cytochrome P4502C19).

artículo científico publicado en 2002

MAO-A and COMT genotypes as possible regulators of perinatal serotonergic symptoms after in utero exposure to SSRIs

artículo científico publicado en 2009

Metabolism and elimination of quinine in healthy volunteers

artículo científico publicado en 2003

Metabolism of alprazolam (a marker of CYP3A4) in hemodialysis patients with persistent inflammation

artículo científico publicado en 2011

Metabolism of citalopram enantiomers in CYP2C19/CYP2D6 phenotyped panels of healthy Swedes

artículo científico publicado en 2003

Molecular genetics of CYP2D6: clinical relevance with focus on psychotropic drugs

artículo científico publicado en 2002

Monoamine metabolites level in CSF is related to the 5-HTT gene polymorphism in treatment-resistant depression

artículo científico publicado en 2007

N-Acetyltransferase-2 (NAT2) phenotype is influenced by genotype-environment interaction in Ethiopians.

artículo científico publicado en 2018

Omeprazole treatment of Korean patients: effects on gastric pH and gastrin release in relation to CYP2C19 geno- and phenotypes

artículo científico publicado en 2004

Pharmacogenetics for off-patent antipsychotics: reframing the risk for tardive dyskinesia and access to essential medicines

artículo científico publicado en 2006

Pharmacogenomics of CYP2D6: molecular genetics, interethnic differences and clinical importance

artículo científico publicado en 2011

Phenotype-genotype variability in the human CYP3A locus as assessed by the probe drug quinine and analyses of variant CYP3A4 alleles

artículo científico publicado en 2005

Plasma levels of 25-hydroxyvitamin D3 and in vivo markers of cytochrome P450 3A activity in Swedes and Koreans: effects of a genetic polymorphism and oral contraceptives

Population Pharmacokinetic Model Linking Plasma and Peripheral Blood Mononuclear Cell Concentrations of Efavirenz and Its Metabolite, 8-Hydroxy-Efavirenz, in HIV Patients

artículo científico publicado en 2017

Prevalence and risk factors for efavirenz-based antiretroviral treatment-associated severe vitamin D deficiency: A prospective cohort study

artículo científico publicado en 2016

Quinine 3-hydroxylation as a biomarker reaction for the activity of CYP3A4 in man.

artículo científico publicado en 2003

Quinine compared to 4β-hydroxycholesterol and midazolam as markers for CYP3A induction by rifampicin

artículo científico publicado en 2014

S-mephenytoin hydroxylation phenotype and CYP2C19 genotype among Ethiopians

artículo científico publicado en 1996

Search for the molecular basis of ultra-rapid CYP2C9-catalysed metabolism: relationship between SNP IVS8-109A>T and the losartan metabolism phenotype in Swedes

artículo científico publicado en 2012

Severe adverse effects in a newborn with two defective CYP2D6 alleles after exposure to paroxetine during late pregnancy

artículo científico publicado en 2004

The African-specific CYP2D617 allele encodes an enzyme with changed substrate specificity

artículo científico publicado en 2002

The Karolinska cocktail for phenotyping of five human cytochrome P450 enzymes.

artículo científico publicado en 2003

Time course of the increase in 4beta-hydroxycholesterol concentration during carbamazepine treatment of paediatric patients with epilepsy

artículo científico publicado en 2008

Voriconazole and fluconazole increase the exposure to oral diazepam

artículo científico publicado en 2007

Xanthine oxidase activity is influenced by environmental factors in Ethiopians

artículo científico publicado en 2003

Lista de obras de

4Beta-hydroxycholesterol is a new endogenous CYP3A marker: relationship to CYP3A5 genotype, quinine 3-hydroxylation and sex in Koreans, Swedes and Tanzanians

4beta-hydroxycholesterol as an endogenous marker for CYP3A4/5 activity. Stability and half-life of elimination after induction with rifampicin

4β-Hydroxycholesterol, an endogenous marker of CYP3A4/5 activity in humans

A common novel CYP2C19 gene variant causes ultrarapid drug metabolism relevant for the drug response to proton pump inhibitors and antidepressants

Allele-specific expression and gene methylation in the control of CYP1A2 mRNA level in human livers

Alprazolam as a probe for CYP3A using a single blood sample: pharmacokinetics of parent drug, and of alpha- and 4-hydroxy metabolites in healthy subjects

Amodiaquine, its desethylated metabolite, or both, inhibit the metabolism of debrisoquine (CYP2D6) and losartan (CYP2C9) in vivo

CYP2C19 activity comparison between Swedes and Koreans: effect of genotype, sex, oral contraceptive use, and smoking

CYP2D6 genotype in relation to perphenazine concentration and pituitary pharmacodynamic tissue sensitivity in Asians: CYP2D6-serotonin-dopamine crosstalk revisited.

CYP2D6 is a major determinant of metoprolol disposition and effects in hospitalized Russian patients treated for acute myocardial infarction

CYP2D6, serotonin and suicide

CYP3A5 genotype has significant effect on quinine 3-hydroxylation in Tanzanians, who have lower total CYP3A activity than a Swedish population

Carriers of the UGT1A4 142T>G gene variant are predisposed to reduced olanzapine exposure--an impact similar to male gender or smoking in schizophrenic patients

Comparison of endogenous 4β-hydroxycholesterol with midazolam as markers for CYP3A4 induction by rifampicin

Comparison ofN-Acetyltransferase-2 Enzyme Genotype-Phenotype and Xanthine Oxidase Enzyme Activity Between Swedes and Koreans

Comparisons of CYP1A2 genetic polymorphisms, enzyme activity and the genotype-phenotype relationship in Swedes and Koreans

Cytochrome P450 3A activity in mothers and their neonates as determined by plasma 4β-hydroxycholesterol

Decreased Activity and Genetic Polymorphisms of CYP2C19 in Behçet's Disease.

Differences in CYP2C9 Genotype and Enzyme Activity Between Swedes and Koreans of Relevance for Personalized Medicine: Role of Ethnicity, Genotype, Smoking, Age, and Sex

Dose of proton pump inhibitors and the CYP2C19 genotype

Effect of SLCO1B1 polymorphism on induction of CYP3A4 by rifampicin

Effects of caffeine intake on the pharmacokinetics of melatonin, a probe drug for CYP1A2 activity ⬇️

Evidence for environmental influence on CYP2D6-catalysed debrisoquine hydroxylation as demonstrated by phenotyping and genotyping of Ethiopians living in Ethiopia or in Sweden

Fluconazole-induced intoxication with phenytoin in a patient with ultra-high activity of CYP2C9.

Genetic and Clinical Factors Affecting Plasma Clozapine Concentration

Genetic polymorphism of CYP1A2 in Ethiopians affecting induction and expression: characterization of novel haplotypes with single-nucleotide polymorphisms in intron 1.

Geographical/interracial differences in polymorphic drug oxidation. Current state of knowledge of cytochromes P450 (CYP) 2D6 and 2C19

High CYP2A6 enzyme activity as measured by a caffeine test and unique distribution of CYP2A6 variant alleles in Ethiopian population

Importance of ethnicity, CYP2B6 and ABCB1 genotype for efavirenz pharmacokinetics and treatment outcomes: a parallel-group prospective cohort study in two sub-Saharan Africa populations

Increased omeprazole metabolism in carriers of the CYP2C19*17 allele; a pharmacokinetic study in healthy volunteers

Induction of CYP1A2 by heavy coffee consumption in Serbs and Swedes

Inflammation down-regulates CYP3A4-catalysed drug metabolism in hemodialysis patients.

Influence of the CYP2D6 polymorphism and hemodialysis on codeine disposition in patients with end-stage renal disease

Inhibition of metoprolol metabolism and potentiation of its effects by paroxetine in routinely treated patients with acute myocardial infarction (AMI).

Interferon-beta treatment in patients with multiple sclerosis does not alter CYP2C19 or CYP2D6 activity

Is there a need to increase the dose of efavirenz during concomitant rifampicin-based antituberculosis therapy in sub-Saharan Africa? The HIV-TB pharmagene study

Kinetics of omeprazole and escitalopram in relation to the CYP2C19*17 allele in healthy subjects

Long-Term Effect of Rifampicin-Based Anti-TB Regimen Coadministration on the Pharmacokinetic Parameters of Efavirenz and 8-Hydroxy-Efavirenz in Ethiopian Patients

Long-term efavirenz pharmacokinetics is comparable between Tanzanian HIV and HIV/Tuberculosis patients with the same CYP2B6*6 genotype

Low daily 10-mg and 20-mg doses of fluvoxamine inhibit the metabolism of both caffeine (cytochrome P4501A2) and omeprazole (cytochrome P4502C19).

MAO-A and COMT genotypes as possible regulators of perinatal serotonergic symptoms after in utero exposure to SSRIs

Metabolism and elimination of quinine in healthy volunteers

Metabolism of alprazolam (a marker of CYP3A4) in hemodialysis patients with persistent inflammation

Metabolism of citalopram enantiomers in CYP2C19/CYP2D6 phenotyped panels of healthy Swedes

Molecular genetics of CYP2D6: clinical relevance with focus on psychotropic drugs

Monoamine metabolites level in CSF is related to the 5-HTT gene polymorphism in treatment-resistant depression

N-Acetyltransferase-2 (NAT2) phenotype is influenced by genotype-environment interaction in Ethiopians.

Omeprazole treatment of Korean patients: effects on gastric pH and gastrin release in relation to CYP2C19 geno- and phenotypes

Pharmacogenetics for off-patent antipsychotics: reframing the risk for tardive dyskinesia and access to essential medicines

Pharmacogenomics of CYP2D6: molecular genetics, interethnic differences and clinical importance

Phenotype-genotype variability in the human CYP3A locus as assessed by the probe drug quinine and analyses of variant CYP3A4 alleles

Plasma levels of 25-hydroxyvitamin D3 and in vivo markers of cytochrome P450 3A activity in Swedes and Koreans: effects of a genetic polymorphism and oral contraceptives

Population Pharmacokinetic Model Linking Plasma and Peripheral Blood Mononuclear Cell Concentrations of Efavirenz and Its Metabolite, 8-Hydroxy-Efavirenz, in HIV Patients

Prevalence and risk factors for efavirenz-based antiretroviral treatment-associated severe vitamin D deficiency: A prospective cohort study

Quinine 3-hydroxylation as a biomarker reaction for the activity of CYP3A4 in man.

Quinine compared to 4β-hydroxycholesterol and midazolam as markers for CYP3A induction by rifampicin

S-mephenytoin hydroxylation phenotype and CYP2C19 genotype among Ethiopians

Search for the molecular basis of ultra-rapid CYP2C9-catalysed metabolism: relationship between SNP IVS8-109A>T and the losartan metabolism phenotype in Swedes

Severe adverse effects in a newborn with two defective CYP2D6 alleles after exposure to paroxetine during late pregnancy

The African-specific CYP2D617 allele encodes an enzyme with changed substrate specificity

The Karolinska cocktail for phenotyping of five human cytochrome P450 enzymes.

Time course of the increase in 4beta-hydroxycholesterol concentration during carbamazepine treatment of paediatric patients with epilepsy

Voriconazole and fluconazole increase the exposure to oral diazepam

Xanthine oxidase activity is influenced by environmental factors in Ethiopians