Lista de obras -

(1)H NMR and FT-IR dataset based structural investigation of poly(amic acid)s and polyimides from 4,4'-diaminostilbene.

artículo científico

9-Demethoxy-medicarpin promotes peak bone mass achievement and has bone conserving effect in ovariectomized mice: Positively regulates osteoblast functions and suppresses osteoclastogenesis

artículo científico publicado en 2015

A Crystal Structure of a Model of the Repeating r(CGG) Transcript Found in Fragile X Syndrome ⬇️

artículo científico publicado el 15 de julio de 2011

A Decade of Boon or Burden: What Has the CHIP Ever Done for Cellular Protein Quality Control Mechanism Implicated in Neurodegeneration and Aging?

artículo científico publicado en 2016

A combined experimental and theoretical (DFT and AIM) studies on synthesis, molecular structure, spectroscopic properties and multiple interactions analysis in a novel ethyl-4-[2-(thiocarbamoyl)hydrazinylidene]-3,5-dimethyl-1H-pyrrole-2-carboxylate

artículo científico publicado en 2013

Acetylamine derivative of diospyrin, a plant-derived binaphthylquinonoid, inhibits human colon cancer growth in Nod-Scid mice.

artículo científico publicado en 2014

An expedient route to imidazo[1,4]diazepin-7-ones via a post-Ugi gold-catalyzed heteroannulation

artículo científico publicado en 2013

An unprecedented alteration in mode of action of IsCT resulting its translocation into bacterial cytoplasm and inhibition of macromolecular syntheses

artículo científico publicado en 2015

Analytical techniques for characterization of biological molecules - proteins and aptamers/oligonucleotides

scientific article published on 26 November 2018

Aptamers in the Therapeutics and Diagnostics Pipelines

scientific article published on 01 July 2018

Benzothiazole Derivative as a Novel Mycobacterium tuberculosis Shikimate Kinase Inhibitor: Identification and Elucidation of Its Allosteric Mode of Inhibition.

artículo científico publicado en 2016

Biosorption of Cd(II) on jatropha fruit coat and seed coat.

artículo científico publicado en 2015

Characterization of G-Quadruplex Motifs in espB, espK, and cyp51 Genes of Mycobacterium tuberculosis as Potential Drug Targets

article

Characterization of highly conserved G-quadruplex motifs as potential drug targets in Streptococcus pneumoniae

artículo científico publicado en 2019

Conformation and intramolecular relaxation dynamics of semiflexible randomly hyperbranched polymers.

artículo científico publicado en 2013

Coordination mode of pentadentate ligand derivative of 5-amino-1,3,4-thiadiazole-2-thiol with nickel(II) and copper(II) metal ions: synthesis, spectroscopic characterization, molecular modeling and fungicidal study

artículo científico publicado en 2014

Design and characterization of short antimicrobial peptides using leucine zipper templates with selectivity towards microorganisms

artículo científico publicado en 2014

Design, Synthesis, and Evaluation of the Kinase Inhibition Potential of Pyridylpyrimidinylaminophenyl Derivatives.

artículo científico publicado en 2017

Designing of a multi-epitope vaccine candidate against Nipah virus by in silico approach: a putative prophylactic solution for the deadly virus

artículo científico publicado en 2020

Development and mechanistic insight into enhanced cytotoxic potential of hyaluronic acid conjugated nanoparticles in CD44 overexpressing cancer cells.

artículo científico publicado en 2016

Differential diagnosis of lung cancer, its metastasis and chronic obstructive pulmonary disease based on serum Vegf, Il-8 and MMP-9.

artículo científico publicado en 2016

Differential roles of ATF-2 in survival and DNA repair contributing to radioresistance induced by autocrine soluble factors in A549 lung cancer cells.

artículo científico publicado en 2014

Discovery of a potent small molecule inhibiting Huntington's disease (HD) pathogenesis via targeting CAG repeats RNA and Poly Q protein

scientific article published on 14 November 2019

Effect of excluded volume on the rheology and transport dynamics of randomly hyperbranched polymers

artículo científico publicado en 2015

Effect of proton and gamma irradiation on human lung carcinoma cells: Gene expression, cell cycle, cell death, epithelial-mesenchymal transition and cancer-stem cell trait as biological end points

scientific article published on 26 July 2015

Emerging methods for structural analysis of protein aggregation

artículo científico publicado en 2017

Endothelial Dll4-Notch signaling in tumor microenvironment: is there any hidden therapeutic opportunity?

artículo científico publicado en 2013

Erratum to: Biosorption of Cd(II) on jatropha fruit coat and seed coat

scientific article published on 17 July 2015

Evidences for Piperine inhibiting cancer by targeting human G-quadruplex DNA sequences.

artículo científico publicado en 2016

Experimental and theoretical (FT-IR, FT-Raman, UV-vis, NMR) spectroscopic analysis and first order hyperpolarizability studies of non-linear optical material: (2E)-3-[4-(methylsulfanyl) phenyl]-1-(4-nitrophenyl) prop-2-en-1-one using density functio

artículo científico publicado en 2014

Exploring the Potential of Small Molecule-Based Therapeutic Approaches for Targeting Trinucleotide Repeat Disorders

scientific article published on 09 August 2019

G-Quadruplex-Forming DNA Aptamers Inhibit the DNA-Binding Function of HupB and Mycobacteriumtuberculosis Entry into Host Cells

artículo científico publicado en 2018

G-quadruplex stabilization in the ions and maltose transporters inhibit Salmonella enterica growth and virulence

scientific article published on 27 June 2018

G4IPDB: A database for G-quadruplex structure forming nucleic acid interacting proteins.

artículo científico publicado en 2016

Generation and application of DNA aptamers against HspX for accurate diagnosis of tuberculous meningitis

scientific article published on 10 July 2018

Global temperature change potential of nitrogen use in agriculture: A 50-year assessment.

artículo científico publicado en 2017

Gp78 E3 Ubiquitin Ligase: Essential Functions and Contributions in Proteostasis

artículo científico publicado en 2017

Heavy Metal Contamination of Soil, Irrigation Water and Vegetables in Peri-Urban Agricultural Areas and Markets of Delhi

artículo científico publicado en 2015

Identification and characterization of two conserved G-quadruplex forming motifs in the Nipah virus genome and their interaction with G-quadruplex specific ligands

scientific article published on 30 January 2020

Intramolecular relaxation of flexible dendrimers with excluded volume

artículo científico publicado en 2014

Lanosterol Suppresses the Aggregation and Cytotoxicity of Misfolded Proteins Linked with Neurodegenerative Diseases.

artículo científico publicado en 2017

Lomofungin and dilomofungin: inhibitors of MBNL1-CUG RNA binding with distinct cellular effects

artículo científico publicado en 2014

Magnetic nanoparticle-mediated hyperthermia therapy induces tumour growth inhibition by apoptosis and Hsp90/AKT modulation.

artículo científico publicado en 2015

Modulation of anti-endotoxin property of Temporin L by minor amino acid substitution in identified phenylalanine zipper sequence.

artículo científico publicado en 2016

Molecular Understanding of Growth Inhibitory Effect from Irradiated to Bystander Tumor Cells in Mouse Fibrosarcoma Tumor Model ⬇️

artículo científico publicado en 2016

Molecular structure (monomeric and dimeric) and hydrogen bonds in 5-benzyl 2-thiohydantoin studied by FT-IR and FT-Raman spectroscopy and DFT calculations

artículo científico publicado en 2014

Myricetin Reduces Toxic Level of CAG Repeats RNA in Huntington's Disease (HD) and Spino Cerebellar Ataxia (SCAs).

artículo científico publicado en 2017

NALDB: nucleic acid ligand database for small molecules targeting nucleic acid.

artículo científico

Nanoemulsion based concomitant delivery of curcumin and etoposide: impact on cross talk between prostate cancer cells and osteoblast during metastasis.

artículo científico publicado en 2014

Orientational relaxation in semiflexible dendrimers.

artículo científico publicado en 2013

Pharmacological activation of protein kinase A improves memory loss and neuropathological changes in a mouse model of dementia of Alzheimer's type

artículo científico publicado en 2017

Piperine Modulates Protein Mediated Toxicity in Fragile X-Associated Tremor/Ataxia Syndrome through Interacting Expanded CGG Repeat (r(CGG)exp) RNA

artículo científico publicado en 2019

Piscidin-1-analogs with double L- and D-lysine residues exhibited different conformations in lipopolysaccharide but comparable anti-endotoxin activities

artículo científico publicado en 2017

Polyphenolic flavonoid (Myricetin) upregulated proteasomal degradation mechanisms: Eliminates neurodegenerative proteins aggregation

artículo científico publicado en 2019

Post-Ugi gold-catalyzed diastereoselective domino cyclization for the synthesis of diversely substituted spiroindolines

artículo científico publicado en 2013

Proteolysis to Identify Protease Substrates: Cleave to Decipher.

artículo científico publicado en 2018

Rational truncation of aptamer for cross-species application to detect krait envenomation

artículo científico publicado en 2018

Rationally designed small molecules targeting toxic CAG repeat RNA that causes Huntington's disease (HD) and spinocerebellar ataxia (SCAs)

artículo científico publicado en 2019

Roles for root iron plaque in sequestration and uptake of heavy metals and metalloids in aquatic and wetland plants

artículo científico publicado en 2014

SMMDB: a web-accessible database for small molecule modulators and their targets involved in neurological diseases

artículo científico publicado en 2018

Scrutinizing the SARS-CoV-2 protein information for the designing an effective vaccine encompassing both the T-cell and B-cell epitopes

scientific article published on 01 April 2020

Selenate mitigates arsenite toxicity in rice (Oryza sativa L.) by reducing arsenic uptake and ameliorates amino acid content and thiol metabolism.

artículo científico publicado en 2016

Selenium ameliorates arsenic induced oxidative stress through modulation of antioxidant enzymes and thiols in rice (Oryza sativa L.).

artículo científico publicado en 2014

Silymarin ameliorates memory deficits and neuropathological changes in mouse model of high-fat-diet-induced experimental dementia

artículo científico publicado en 2014

Single Amino Acid Substitutions at Specific Positions of the Heptad Repeat Sequence of Piscidin-1 Yielded Novel Analogs That Show Low Cytotoxicity and In Vitro and In Vivo Antiendotoxin Activity

artículo científico publicado en 2016

Structural Insight into the interaction of Flavonoids with Human Telomeric Sequence

artículo científico publicado en 2015

Structural Insights Reveal the Dynamics of the Repeating r(CAG) Transcript Found in Huntington's Disease (HD) and Spinocerebellar Ataxias (SCAs)

artículo científico publicado en 2015

Structural insight for the recognition of G-quadruplex structure at human c-myc promoter sequence by flavonoid Quercetin

artículo científico publicado en 2017

Structural switching electrochemical DNA aptasensor for the rapid diagnosis of tuberculous meningitis

scientific article published on 26 March 2019

Switching the regioselectivity via indium(III) and gold(I) catalysis: a post-Ugi intramolecular hydroarylation to azepino- and azocino-[c,d]indolones.

artículo científico publicado en 2013

Synthesis of 2-alkoxy and 2-benzyloxy analogues of estradiol as anti-breast cancer agents through microtubule stabilization

artículo científico publicado en 2014

Synthesis of neolignans as microtubule stabilisers.

artículo científico publicado en 2014

Synthesis of β-C-Glycopyranosyl Aldehydes and 2,6-Anhydro-heptitols

scientific article published on 08 October 2015

Synthesis, characterization and augmented anticancer potential of PEG-betulinic acid conjugate.

artículo científico publicado en 2016

Thorium induced cytoproliferative effect in human liver cell HepG2: role of insulin-like growth factor 1 receptor and downstream signaling.

artículo científico publicado en 2014

Variants of self-assembling peptide, KLD-12 that show both rapid fracture healing and antimicrobial properties.

artículo científico publicado en 2015

Lista de obras de

(1)H NMR and FT-IR dataset based structural investigation of poly(amic acid)s and polyimides from 4,4'-diaminostilbene.

9-Demethoxy-medicarpin promotes peak bone mass achievement and has bone conserving effect in ovariectomized mice: Positively regulates osteoblast functions and suppresses osteoclastogenesis

A Crystal Structure of a Model of the Repeating r(CGG) Transcript Found in Fragile X Syndrome ⬇️

A Decade of Boon or Burden: What Has the CHIP Ever Done for Cellular Protein Quality Control Mechanism Implicated in Neurodegeneration and Aging?

A combined experimental and theoretical (DFT and AIM) studies on synthesis, molecular structure, spectroscopic properties and multiple interactions analysis in a novel ethyl-4-[2-(thiocarbamoyl)hydrazinylidene]-3,5-dimethyl-1H-pyrrole-2-carboxylate

Acetylamine derivative of diospyrin, a plant-derived binaphthylquinonoid, inhibits human colon cancer growth in Nod-Scid mice.

An expedient route to imidazo[1,4]diazepin-7-ones via a post-Ugi gold-catalyzed heteroannulation

An unprecedented alteration in mode of action of IsCT resulting its translocation into bacterial cytoplasm and inhibition of macromolecular syntheses

Analytical techniques for characterization of biological molecules - proteins and aptamers/oligonucleotides

Aptamers in the Therapeutics and Diagnostics Pipelines

Benzothiazole Derivative as a Novel Mycobacterium tuberculosis Shikimate Kinase Inhibitor: Identification and Elucidation of Its Allosteric Mode of Inhibition.

Biosorption of Cd(II) on jatropha fruit coat and seed coat.

Characterization of G-Quadruplex Motifs in espB, espK, and cyp51 Genes of Mycobacterium tuberculosis as Potential Drug Targets

Characterization of highly conserved G-quadruplex motifs as potential drug targets in Streptococcus pneumoniae

Conformation and intramolecular relaxation dynamics of semiflexible randomly hyperbranched polymers.

Coordination mode of pentadentate ligand derivative of 5-amino-1,3,4-thiadiazole-2-thiol with nickel(II) and copper(II) metal ions: synthesis, spectroscopic characterization, molecular modeling and fungicidal study

Design and characterization of short antimicrobial peptides using leucine zipper templates with selectivity towards microorganisms

Design, Synthesis, and Evaluation of the Kinase Inhibition Potential of Pyridylpyrimidinylaminophenyl Derivatives.

Designing of a multi-epitope vaccine candidate against Nipah virus by in silico approach: a putative prophylactic solution for the deadly virus

Development and mechanistic insight into enhanced cytotoxic potential of hyaluronic acid conjugated nanoparticles in CD44 overexpressing cancer cells.

Differential diagnosis of lung cancer, its metastasis and chronic obstructive pulmonary disease based on serum Vegf, Il-8 and MMP-9.

Differential roles of ATF-2 in survival and DNA repair contributing to radioresistance induced by autocrine soluble factors in A549 lung cancer cells.

Discovery of a potent small molecule inhibiting Huntington's disease (HD) pathogenesis via targeting CAG repeats RNA and Poly Q protein

Effect of excluded volume on the rheology and transport dynamics of randomly hyperbranched polymers

Effect of proton and gamma irradiation on human lung carcinoma cells: Gene expression, cell cycle, cell death, epithelial-mesenchymal transition and cancer-stem cell trait as biological end points

Emerging methods for structural analysis of protein aggregation

Endothelial Dll4-Notch signaling in tumor microenvironment: is there any hidden therapeutic opportunity?

Erratum to: Biosorption of Cd(II) on jatropha fruit coat and seed coat

Evidences for Piperine inhibiting cancer by targeting human G-quadruplex DNA sequences.

Experimental and theoretical (FT-IR, FT-Raman, UV-vis, NMR) spectroscopic analysis and first order hyperpolarizability studies of non-linear optical material: (2E)-3-[4-(methylsulfanyl) phenyl]-1-(4-nitrophenyl) prop-2-en-1-one using density functio

Exploring the Potential of Small Molecule-Based Therapeutic Approaches for Targeting Trinucleotide Repeat Disorders

G-Quadruplex-Forming DNA Aptamers Inhibit the DNA-Binding Function of HupB and Mycobacteriumtuberculosis Entry into Host Cells

G-quadruplex stabilization in the ions and maltose transporters inhibit Salmonella enterica growth and virulence

G4IPDB: A database for G-quadruplex structure forming nucleic acid interacting proteins.

Generation and application of DNA aptamers against HspX for accurate diagnosis of tuberculous meningitis

Global temperature change potential of nitrogen use in agriculture: A 50-year assessment.

Gp78 E3 Ubiquitin Ligase: Essential Functions and Contributions in Proteostasis

Heavy Metal Contamination of Soil, Irrigation Water and Vegetables in Peri-Urban Agricultural Areas and Markets of Delhi

Identification and characterization of two conserved G-quadruplex forming motifs in the Nipah virus genome and their interaction with G-quadruplex specific ligands

Intramolecular relaxation of flexible dendrimers with excluded volume

Lanosterol Suppresses the Aggregation and Cytotoxicity of Misfolded Proteins Linked with Neurodegenerative Diseases.

Lomofungin and dilomofungin: inhibitors of MBNL1-CUG RNA binding with distinct cellular effects

Magnetic nanoparticle-mediated hyperthermia therapy induces tumour growth inhibition by apoptosis and Hsp90/AKT modulation.

Modulation of anti-endotoxin property of Temporin L by minor amino acid substitution in identified phenylalanine zipper sequence.

Molecular Understanding of Growth Inhibitory Effect from Irradiated to Bystander Tumor Cells in Mouse Fibrosarcoma Tumor Model ⬇️

Molecular structure (monomeric and dimeric) and hydrogen bonds in 5-benzyl 2-thiohydantoin studied by FT-IR and FT-Raman spectroscopy and DFT calculations

Myricetin Reduces Toxic Level of CAG Repeats RNA in Huntington's Disease (HD) and Spino Cerebellar Ataxia (SCAs).

NALDB: nucleic acid ligand database for small molecules targeting nucleic acid.

Nanoemulsion based concomitant delivery of curcumin and etoposide: impact on cross talk between prostate cancer cells and osteoblast during metastasis.

Orientational relaxation in semiflexible dendrimers.

Pharmacological activation of protein kinase A improves memory loss and neuropathological changes in a mouse model of dementia of Alzheimer's type

Piperine Modulates Protein Mediated Toxicity in Fragile X-Associated Tremor/Ataxia Syndrome through Interacting Expanded CGG Repeat (r(CGG)exp) RNA

Piscidin-1-analogs with double L- and D-lysine residues exhibited different conformations in lipopolysaccharide but comparable anti-endotoxin activities

Polyphenolic flavonoid (Myricetin) upregulated proteasomal degradation mechanisms: Eliminates neurodegenerative proteins aggregation

Post-Ugi gold-catalyzed diastereoselective domino cyclization for the synthesis of diversely substituted spiroindolines

Proteolysis to Identify Protease Substrates: Cleave to Decipher.

Rational truncation of aptamer for cross-species application to detect krait envenomation

Rationally designed small molecules targeting toxic CAG repeat RNA that causes Huntington's disease (HD) and spinocerebellar ataxia (SCAs)

Roles for root iron plaque in sequestration and uptake of heavy metals and metalloids in aquatic and wetland plants

SMMDB: a web-accessible database for small molecule modulators and their targets involved in neurological diseases

Scrutinizing the SARS-CoV-2 protein information for the designing an effective vaccine encompassing both the T-cell and B-cell epitopes

Selenate mitigates arsenite toxicity in rice (Oryza sativa L.) by reducing arsenic uptake and ameliorates amino acid content and thiol metabolism.

Selenium ameliorates arsenic induced oxidative stress through modulation of antioxidant enzymes and thiols in rice (Oryza sativa L.).

Silymarin ameliorates memory deficits and neuropathological changes in mouse model of high-fat-diet-induced experimental dementia

Single Amino Acid Substitutions at Specific Positions of the Heptad Repeat Sequence of Piscidin-1 Yielded Novel Analogs That Show Low Cytotoxicity and In Vitro and In Vivo Antiendotoxin Activity

Structural Insight into the interaction of Flavonoids with Human Telomeric Sequence

Structural Insights Reveal the Dynamics of the Repeating r(CAG) Transcript Found in Huntington's Disease (HD) and Spinocerebellar Ataxias (SCAs)

Structural insight for the recognition of G-quadruplex structure at human c-myc promoter sequence by flavonoid Quercetin

Structural switching electrochemical DNA aptasensor for the rapid diagnosis of tuberculous meningitis

Switching the regioselectivity via indium(III) and gold(I) catalysis: a post-Ugi intramolecular hydroarylation to azepino- and azocino-[c,d]indolones.

Synthesis of 2-alkoxy and 2-benzyloxy analogues of estradiol as anti-breast cancer agents through microtubule stabilization

Synthesis of neolignans as microtubule stabilisers.

Synthesis of β-C-Glycopyranosyl Aldehydes and 2,6-Anhydro-heptitols

Synthesis, characterization and augmented anticancer potential of PEG-betulinic acid conjugate.

Thorium induced cytoproliferative effect in human liver cell HepG2: role of insulin-like growth factor 1 receptor and downstream signaling.

Variants of self-assembling peptide, KLD-12 that show both rapid fracture healing and antimicrobial properties.