Lista de obras -

3D RESOLUTION MEASURE FOR MULTIFOCAL PLANE MICROSCOPY.

artículo científico publicado en 2008

3D single molecule tracking and superresolution microscopy using multifocal plane microscopy

artículo científico publicado en 2012

3D single molecule tracking of quantum-dot labeled antibody molecules using multifocal plane microscopy

artículo científico publicado en 2010

3D single molecule tracking with multifocal plane microscopy reveals rapid intercellular transferrin transport at epithelial cell barriers

artículo científico publicado en 2012

A 3D Resolution Measure for Optical Microscopy

artículo científico publicado en 2009

A Distinct Class of Antibodies May Be an Indicator of Gray Matter Autoimmunity in Early and Established Relapsing Remitting Multiple Sclerosis Patients.

artículo científico publicado en 2015

A comparative study of high resolution microscopy imaging modalities using a three-dimensional resolution measure.

artículo científico publicado en 2009

A resolution measure for three-dimensional microscopy.

artículo científico publicado en 2009

A software framework for the analysis of complex microscopy image data.

artículo científico publicado en 2010

A state space based approach to localizing single molecules from multi-emitter images.

artículo científico publicado en 2017

A stochastic analysis of distance estimation approaches in single molecule microscopy - quantifying the resolution limits of photon-limited imaging systems.

artículo científico publicado en 2013

A two-stage method for automated detection of ring-like endosomes in fluorescent microscopy images

scientific article published on 27 June 2019

Achievable accuracy of parameter estimation for multidimensional NMR experiments.

artículo científico publicado en 2002

An information-theoretic approach to designing the plane spacing for multifocal plane microscopy.

artículo científico publicado en 2015

Analyses of TCR clustering at the T cell-antigen-presenting cell interface and its impact on the activation of naive CD4+ T cells

artículo científico publicado en 2006

Analyses of the recycling receptor, FcRn, in live cells reveal novel pathways for lysosomal delivery.

artículo científico publicado en 2009

Analysis of autoreactive T cells associated with murine collagen-induced arthritis using peptide-MHC multimers.

artículo científico publicado en 2004

Analysis of exponential data using a noniterative technique: application to surface plasmon experiments.

artículo científico publicado en 2003

Antibody engineering: the use of Escherichia coli as an expression host ⬇️

artículo científico publicado el 1 de abril de 1992

Antibody targeting of HER2/HER3 signaling overcomes heregulin-induced resistance to PI3K inhibition in prostate cancer

artículo científico publicado en 2014

Antigen dynamics govern the induction of CD4(+) T cell tolerance during autoimmunity.

artículo científico publicado en 2016

Antigen specificity of clonally expanded and receptor edited cerebrospinal fluid B cells from patients with relapsing remitting MS

artículo científico publicado en 2007

Autoantibody depletion ameliorates disease in murine experimental autoimmune encephalomyelitis

artículo científico publicado en 2013

Autoantigen immunization at different sites reveals a role for anti-inflammatory effects of IFN-gamma in regulating susceptibility to experimental autoimmune encephalomyelitis.

artículo científico publicado en 2009

BCAP links IL-1R to the PI3K-mTOR pathway and regulates pathogenic Th17 cell differentiation

artículo científico publicado en 2018

Beyond Rayleigh's criterion: a resolution measure with application to single-molecule microscopy.

artículo científico publicado en 2006

Catabolism of the murine IgG1 molecule: evidence that both CH2-CH3 domain interfaces are required for persistence of IgG1 in the circulation of mice

scientific article published on 01 October 1994

Chapter 4: Multitasking by exploitation of intracellular transport functions the many faces of FcRn.

artículo científico publicado en 2009

Cloning and expression inEscherichia coliof the insecticidal δ-endotoxin gene ofBacillus thuringiensisvar.israelensis ⬇️

artículo científico publicado el 1 de octubre de 1984

Commentary: "There's been a Flaw in Our Thinking".

artículo científico publicado en 2015

Comparative stabilities in vitro and in vivo of a recombinant mouse antibody FvCys fragment and a bisFvCys conjugate ⬇️

artículo científico publicado el 1 de julio de 1992

Comparative studies of rat IgG to further delineate the Fc : FcRn interaction site ⬇️

artículo científico publicado el 1 de julio de 1998

Comparison of estimation algorithms in single-molecule localization.

artículo científico publicado en 2010

Compensation for loss of ligand activity in surface plasmon resonance experiments.

artículo científico publicado en 2002

Conditional deletion of the MHC class I-related receptor FcRn reveals the sites of IgG homeostasis in mice

scholarly article

Conferring the binding properties of the mouse MHC class I-related receptor, FcRn, onto the human ortholog by sequential rounds of site-directed mutagenesis

scientific article published on 16 December 2004

Crystal structure of a T cell receptor Valpha11 (AV11S5) domain: new canonical forms for the first and second complementarity determining regions

artículo científico publicado en 2001

Designing the focal plane spacing for multifocal plane microscopy

artículo científico publicado en 2014

Detection of autoreactive T cells in H-2u mice using peptide-MHC multimers

artículo científico publicado en 2000

Determination of localization accuracy based on experimentally acquired image sets: applications to single molecule microscopy.

artículo científico publicado en 2015

Divergent activities of an engineered antibody in murine and human systems have implications for therapeutic antibodies

artículo científico publicado en 2006

Dual objective fluorescence microscopy for single molecule imaging applications

artículo científico publicado en 2009

Elucidation of intracellular recycling pathways leading to exocytosis of the Fc receptor, FcRn, by using multifocal plane microscopy

artículo científico publicado en 2007

Engineered clearing agents for the selective depletion of antigen-specific antibodies

artículo científico publicado en 2017

Engineering a HER2-specific antibody-drug conjugate to increase lysosomal delivery and therapeutic efficacy

scientific article published on 01 April 2019

Engineering multivalent antibodies to target heregulin-induced HER3 signaling in breast cancer cells

artículo científico publicado en 2013

Engineering the Fc region of immunoglobulin G to modulate in vivo antibody levels

artículo científico publicado en 2005

Evidence that the hinge region plays a role in maintaining serum levels of the murine IgG1 molecule

artículo científico publicado en 1995

Evidence to support the cellular mechanism involved in serum IgG homeostasis in humans

artículo científico publicado en 2003

Exocytosis of IgG as mediated by the receptor, FcRn: an analysis at the single-molecule level

artículo científico publicado en 2004

Expression and Secretion of T-Cell Receptor Valpha and Vbeta Domains using Escherichia coli as a Host ⬇️

artículo científico publicado el 1 de agosto de 1991

Expression and characterization of recombinant soluble peptide: I-A complexes associated with murine experimental autoimmune diseases ⬇️

artículo científico publicado el 15 de junio de 1998

Expression of the tyrosine phosphatase SRC homology 2 domain-containing protein tyrosine phosphatase 1 determines T cell activation threshold and severity of experimental autoimmune encephalomyelitis.

artículo científico publicado en 2002

FISHER INFORMATION FOR EMCCD IMAGING WITH APPLICATION TO SINGLE MOLECULE MICROSCOPY

artículo científico publicado en 2010

FcRn: from molecular interactions to regulation of IgG pharmacokinetics and functions

artículo científico

FcRn: the MHC class I-related receptor that is more than an IgG transporter ⬇️

artículo científico publicado el 1 de diciembre de 1997

Feedback regulation of murine autoimmunity via dominant anti-inflammatory effects of interferon gamma.

artículo científico publicado en 2007

Fisher information matrix for branching processes with application to electron-multiplying charge-coupled devices

artículo científico publicado en 2012

Fisher information theory for parameter estimation in single molecule microscopy: tutorial

artículo científico publicado en 2016

Fluorescent Microspheres as Point Sources: A Localization Study.

artículo científico publicado en 2015

From sorting endosomes to exocytosis: association of Rab4 and Rab11 GTPases with the Fc receptor, FcRn, during recycling.

artículo científico publicado en 2005

Functional expression of the MHC class I-related receptor, FcRn, in endothelial cells of mice.

artículo científico publicado en 1998

Generation of mutated variants of the human form of the MHC class I-related receptor, FcRn, with increased affinity for mouse immunoglobulin G.

artículo científico publicado en 2003

Hepatic function of FcRn revealed: Implications for overcoming drug-mediated hepatotoxicity.

artículo científico publicado en 2017

High accuracy 3D quantum dot tracking with multifocal plane microscopy for the study of fast intracellular dynamics in live cells

artículo científico publicado en 2008

How Accurately Can a Single Molecule be Localized when Imaged Through an Optical Microscope?

artículo científico publicado en 2004

How accurately can a single molecule be localized in three dimensions using a fluorescence microscope?

artículo científico publicado en 2005

Identification and function of neonatal Fc receptor in mammary gland of lactating mice.

artículo científico publicado en 1999

Improved single particle localization accuracy with dual objective multifocal plane microscopy.

artículo científico publicado en 2009

Increasing the affinity of a human IgG1 for the neonatal Fc receptor: biological consequences.

artículo científico publicado en 2002

Increasing the serum persistence of an IgG fragment by random mutagenesis.

artículo científico

Inhibitory receptors bind ANGPTLs and support blood stem cells and leukaemia development

artículo científico publicado en 2012

Intensity-based axial localization approaches for multifocal plane microscopy.

artículo científico publicado en 2017

Investigating the usage of point spread functions in point source and microsphere localization.

artículo científico publicado en 2016

Investigation of the numerics of point spread function integration in single molecule localization

artículo científico publicado en 2015

Localization accuracy in single molecule microscopy using electron-multiplying charge-coupled device cameras.

scientific article published on March 2012

Localization accuracy in single-molecule microscopy

artículo científico publicado en 2004

Localizing single molecules in three dimensions - a brief review

artículo científico publicado en 2008

Loss of expression of the recycling receptor, FcRn, promotes tumor cell growth by increasing albumin consumption

artículo científico publicado en 2016

Macrophage and NK-mediated killing of precursor-B acute lymphoblastic leukemia cells targeted with a-fucosylated anti-CD19 humanized antibodies

artículo científico publicado en 2013

Macrophage-Mediated Trogocytosis Leads to Death of Antibody-Opsonized Tumor Cells

artículo científico publicado en 2016

Mapping the site on human IgG for binding of the MHC class I-related receptor, FcRn

scientific article published on 01 September 1999

Microscope calibration protocol for single-molecule microscopy

artículo científico publicado en 2021

Molecular mimics can induce a nonautoaggressive repertoire that preempts induction of autoimmunity.

artículo científico publicado en 2010

Molecular requirements for T cell recognition by a major histocompatibility complex class II-restricted T cell receptor: the involvement of the fourth hypervariable loop of the Valpha domain.

artículo científico publicado en 1999

Myelin oligodendrocyte glycoprotein-specific antibodies from multiple sclerosis patients exacerbate disease in a humanized mouse model.

artículo científico publicado en 2017

Negative selection during the peripheral immune response to antigen

artículo científico publicado en 2001

Neonatal Fc receptor antagonist efgartigimod safely and sustainably reduces IgGs in humans

artículo científico publicado en 2018

Neonatal Fc receptor blockade by Fc engineering ameliorates arthritis in a murine model

artículo científico publicado en 2011

Neonatal Fc receptor expression in macrophages is indispensable for IgG homeostasis

scientific article published on 30 April 2019

New results on the single molecule localization problem in two and three dimensions

artículo científico publicado en 2015

Noise suppression of point spread functions and its influence on deconvolution of three-dimensional fluorescence microscopy image sets.

artículo científico publicado en 2005

Phagocytosis of antibody-opsonized tumor cells leads to the formation of a discrete vacuolar compartment in macrophages.

artículo científico publicado en 2018

Phase 2 study of efgartigimod, a novel FcRn antagonist, in adult patients with primary immune thrombocytopenia

scientific article published on 10 December 2019

Potential of a unique antibody gene signature to predict conversion to clinically definite multiple sclerosis.

artículo científico publicado en 2009

Protection against experimental autoimmune encephalomyelitis generated by a recombinant adenovirus vector expressing the V beta 8.2 TCR is disrupted by coadministration with vectors expressing either IL-4 or -10.

artículo científico publicado en 2003

Quantitative Aspects of Single Molecule Microscopy

artículo científico publicado en 2015

Quantitative study of single molecule location estimation techniques

artículo científico publicado en 2009

Randomized phase 2 study of FcRn antagonist efgartigimod in generalized myasthenia gravis

artículo científico publicado en 2019

Recombinant T cell receptor molecules can prevent and reverse experimental autoimmune encephalomyelitis: dose effects and involvement of both CD4 and CD8 T cells ⬇️

artículo científico publicado el 15 de noviembre de 1997

Remote focusing multifocal plane microscopy for the imaging of 3D single molecule dynamics with cellular context

artículo científico publicado en 2017

Secretion of T cell receptor fragments from recombinant Escherichia coli cells

artículo científico publicado el 20 de abril de 1992

Selective depletion of antigen-specific antibodies for the treatment of demyelinating disease

artículo científico publicado en 2020

Simultaneous imaging of different focal planes in fluorescence microscopy for the study of cellular dynamics in three dimensions.

artículo científico publicado en 2004

State space approach to single molecule localization in fluorescence microscopy.

artículo científico publicado en 2017

Structural snapshot of aberrant antigen presentation linked to autoimmunity: the immunodominant epitope of MBP complexed with I-Au

artículo científico publicado en 2002

T cell recognition of distinct peptide:I-Au conformers in murine experimental autoimmune encephalomyelitis.

artículo científico publicado en 2003

Targeting FcRn for the modulation of antibody dynamics

artículo científico publicado en 2015

Targeting FcRn for therapy: from live cell imaging to in vivo studies in mice.

artículo científico publicado en 2014

Targeting FcRn to Generate Antibody-Based Therapeutics

artículo científico publicado en 2018

Targeting Phosphatidylserine with Calcium-Dependent Protein-Drug Conjugates for the Treatment of Cancer

artículo científico publicado en 2017

Targeting the neonatal fc receptor for antigen delivery using engineered fc fragments.

artículo científico publicado en 2008

The MHC class I related Fc receptor, FcRn, is expressed in the epithelial cells of the human mammary gland.

artículo científico publicado en 2003

The MHC class I-related receptor, FcRn, plays an essential role in the maternofetal transfer of gamma-globulin in humans

artículo científico publicado en 2001

The central residues of a T cell receptor sequence motif are key determinants of autoantigen recognition in murine experimental autoimmune encephalomyelitis.

artículo científico publicado en 2005

The choice of reference cell in the analysis of kinetic data using BIAcore.

artículo científico publicado en 1999

The effect of pH dependence of antibody-antigen interactions on subcellular trafficking dynamics

artículo científico publicado en 2013

The encephalitogenic, human myelin oligodendrocyte glycoprotein-induced antibody repertoire is directed toward multiple epitopes in C57BL/6-immunized mice.

artículo científico publicado en 2013

The influence of signal noise on the accuracy of kinetic constants measured by surface plasmon resonance experiments

artículo científico publicado en 1999

The level of HER2 expression is a predictor of antibody-HER2 trafficking behavior in cancer cells

artículo científico publicado en 2014

Transcytosis and catabolism of antibody

artículo científico publicado en 2002

Two approximations for the geometric model of signal amplification in an electron-multiplying charge-coupled device detector.

artículo científico publicado en 2013

Ultrahigh accuracy imaging modality for super-localization microscopy.

artículo científico publicado en 2013

Use of Fc-Engineered Antibodies as Clearing Agents to Increase Contrast During PET.

artículo científico publicado en 2014

Using multifocal plane microscopy to reveal novel trafficking processes in the recycling pathway

artículo científico publicado en 2013

Vaccination with a recombinant V alpha domain of a TCR prevents the development of collagen-induced arthritis ⬇️

artículo científico publicado el 1 de noviembre de 1995

Visualizing the site and dynamics of IgG salvage by the MHC class I-related receptor, FcRn.

artículo científico publicado en 2004

Lista de obras de

3D RESOLUTION MEASURE FOR MULTIFOCAL PLANE MICROSCOPY.

3D single molecule tracking and superresolution microscopy using multifocal plane microscopy

3D single molecule tracking of quantum-dot labeled antibody molecules using multifocal plane microscopy

3D single molecule tracking with multifocal plane microscopy reveals rapid intercellular transferrin transport at epithelial cell barriers

A 3D Resolution Measure for Optical Microscopy

A Distinct Class of Antibodies May Be an Indicator of Gray Matter Autoimmunity in Early and Established Relapsing Remitting Multiple Sclerosis Patients.

A comparative study of high resolution microscopy imaging modalities using a three-dimensional resolution measure.

A resolution measure for three-dimensional microscopy.

A software framework for the analysis of complex microscopy image data.

A state space based approach to localizing single molecules from multi-emitter images.

A stochastic analysis of distance estimation approaches in single molecule microscopy - quantifying the resolution limits of photon-limited imaging systems.

A two-stage method for automated detection of ring-like endosomes in fluorescent microscopy images

Achievable accuracy of parameter estimation for multidimensional NMR experiments.

An information-theoretic approach to designing the plane spacing for multifocal plane microscopy.

Analyses of TCR clustering at the T cell-antigen-presenting cell interface and its impact on the activation of naive CD4+ T cells

Analyses of the recycling receptor, FcRn, in live cells reveal novel pathways for lysosomal delivery.

Analysis of autoreactive T cells associated with murine collagen-induced arthritis using peptide-MHC multimers.

Analysis of exponential data using a noniterative technique: application to surface plasmon experiments.

Antibody engineering: the use of Escherichia coli as an expression host ⬇️

Antibody targeting of HER2/HER3 signaling overcomes heregulin-induced resistance to PI3K inhibition in prostate cancer

Antigen dynamics govern the induction of CD4(+) T cell tolerance during autoimmunity.

Antigen specificity of clonally expanded and receptor edited cerebrospinal fluid B cells from patients with relapsing remitting MS

Autoantibody depletion ameliorates disease in murine experimental autoimmune encephalomyelitis

Autoantigen immunization at different sites reveals a role for anti-inflammatory effects of IFN-gamma in regulating susceptibility to experimental autoimmune encephalomyelitis.

BCAP links IL-1R to the PI3K-mTOR pathway and regulates pathogenic Th17 cell differentiation

Beyond Rayleigh's criterion: a resolution measure with application to single-molecule microscopy.

Catabolism of the murine IgG1 molecule: evidence that both CH2-CH3 domain interfaces are required for persistence of IgG1 in the circulation of mice

Chapter 4: Multitasking by exploitation of intracellular transport functions the many faces of FcRn.

Cloning and expression inEscherichia coliof the insecticidal δ-endotoxin gene ofBacillus thuringiensisvar.israelensis ⬇️

Commentary: "There's been a Flaw in Our Thinking".

Comparative stabilities in vitro and in vivo of a recombinant mouse antibody FvCys fragment and a bisFvCys conjugate ⬇️

Comparative studies of rat IgG to further delineate the Fc : FcRn interaction site ⬇️

Comparison of estimation algorithms in single-molecule localization.

Compensation for loss of ligand activity in surface plasmon resonance experiments.

Conditional deletion of the MHC class I-related receptor FcRn reveals the sites of IgG homeostasis in mice

Conferring the binding properties of the mouse MHC class I-related receptor, FcRn, onto the human ortholog by sequential rounds of site-directed mutagenesis

Crystal structure of a T cell receptor Valpha11 (AV11S5) domain: new canonical forms for the first and second complementarity determining regions

Designing the focal plane spacing for multifocal plane microscopy

Detection of autoreactive T cells in H-2u mice using peptide-MHC multimers

Determination of localization accuracy based on experimentally acquired image sets: applications to single molecule microscopy.

Divergent activities of an engineered antibody in murine and human systems have implications for therapeutic antibodies

Dual objective fluorescence microscopy for single molecule imaging applications

Elucidation of intracellular recycling pathways leading to exocytosis of the Fc receptor, FcRn, by using multifocal plane microscopy

Engineered clearing agents for the selective depletion of antigen-specific antibodies

Engineering a HER2-specific antibody-drug conjugate to increase lysosomal delivery and therapeutic efficacy

Engineering multivalent antibodies to target heregulin-induced HER3 signaling in breast cancer cells

Engineering the Fc region of immunoglobulin G to modulate in vivo antibody levels

Evidence that the hinge region plays a role in maintaining serum levels of the murine IgG1 molecule

Evidence to support the cellular mechanism involved in serum IgG homeostasis in humans

Exocytosis of IgG as mediated by the receptor, FcRn: an analysis at the single-molecule level

Expression and Secretion of T-Cell Receptor Valpha and Vbeta Domains using Escherichia coli as a Host ⬇️

Expression and characterization of recombinant soluble peptide: I-A complexes associated with murine experimental autoimmune diseases ⬇️

Expression of the tyrosine phosphatase SRC homology 2 domain-containing protein tyrosine phosphatase 1 determines T cell activation threshold and severity of experimental autoimmune encephalomyelitis.

FISHER INFORMATION FOR EMCCD IMAGING WITH APPLICATION TO SINGLE MOLECULE MICROSCOPY

FcRn: from molecular interactions to regulation of IgG pharmacokinetics and functions

FcRn: the MHC class I-related receptor that is more than an IgG transporter ⬇️

Feedback regulation of murine autoimmunity via dominant anti-inflammatory effects of interferon gamma.

Fisher information matrix for branching processes with application to electron-multiplying charge-coupled devices

Fisher information theory for parameter estimation in single molecule microscopy: tutorial

Fluorescent Microspheres as Point Sources: A Localization Study.

From sorting endosomes to exocytosis: association of Rab4 and Rab11 GTPases with the Fc receptor, FcRn, during recycling.

Functional expression of the MHC class I-related receptor, FcRn, in endothelial cells of mice.

Generation of mutated variants of the human form of the MHC class I-related receptor, FcRn, with increased affinity for mouse immunoglobulin G.

Hepatic function of FcRn revealed: Implications for overcoming drug-mediated hepatotoxicity.

High accuracy 3D quantum dot tracking with multifocal plane microscopy for the study of fast intracellular dynamics in live cells

How Accurately Can a Single Molecule be Localized when Imaged Through an Optical Microscope?

How accurately can a single molecule be localized in three dimensions using a fluorescence microscope?

Identification and function of neonatal Fc receptor in mammary gland of lactating mice.

Improved single particle localization accuracy with dual objective multifocal plane microscopy.

Increasing the affinity of a human IgG1 for the neonatal Fc receptor: biological consequences.

Increasing the serum persistence of an IgG fragment by random mutagenesis.

Inhibitory receptors bind ANGPTLs and support blood stem cells and leukaemia development

Intensity-based axial localization approaches for multifocal plane microscopy.

Investigating the usage of point spread functions in point source and microsphere localization.

Investigation of the numerics of point spread function integration in single molecule localization

Localization accuracy in single molecule microscopy using electron-multiplying charge-coupled device cameras.

Localization accuracy in single-molecule microscopy

Localizing single molecules in three dimensions - a brief review

Loss of expression of the recycling receptor, FcRn, promotes tumor cell growth by increasing albumin consumption