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A novel molecular design of thrombin receptor antagonist

artículo científico publicado en 1999

Active Sites of Spinoxin, a Potassium Channel Scorpion Toxin, Elucidated by Systematic Alanine Scanning

artículo científico publicado en 2016

Aggregation feature of fluorine-substituted benzene rings and intermolecular C-H.F interaction: crystal structure analyses of mono- and trifluoro-L-phenylalanines.

artículo científico publicado en 2003

Bisphenol AF: Halogen bonding effect is a major driving force for the dual ERα-agonist and ERβ-antagonist activities

scientific article published on 18 December 2019

Comparison between coacervation property and secondary structure of synthetic peptides, Ile-containing elastin-derived pentapeptide repeats

artículo científico publicado en 2013

DMSO-Perturbing Assay for Identifying Promiscuous Enzyme Inhibitors

scientific article published on 10 May 2019

Design and synthesis of para-fluorophenylalanine amide derivatives as thrombin receptor antagonists

artículo científico publicado en 1999

Design of Phenylalanine-Containing Elastin-Derived Peptides Exhibiting Highly Potent Self-Assembling Capability

artículo científico publicado en 2015

Design of serine protease inhibitors with conformation restricted by amino acid side-chain-side-chain CH/pie interaction

artículo científico publicado en 1999

Designed modification of partial agonist of ORL1 nociceptin receptor for conversion into highly potent antagonist.

artículo científico publicado en 2007

Development of short and highly potent self-assembling elastin-derived pentapeptide repeats containing aromatic amino acid residues.

artículo científico publicado en 2015

Differential receptor binding characteristics of consecutive phenylalanines in micro-opioid specific peptide ligand endomorphin-2.

artículo científico publicado en 2007

Dimerization effects on coacervation property of an elastin-derived synthetic peptide (FPGVG)5.

artículo científico publicado en 2016

Discriminatory synergistic effect of Trp-substitutions in superagonist [(Arg/Lys)(14), (Arg/Lys)(15)]nociceptin on ORL1 receptor binding and activation.

artículo científico publicado en 2009

Early identification of promiscuous attributes of aldose reductase inhibitors using a DMSO-perturbation assay

scientific article published on 09 November 2019

Enhancement of Self-Aggregation Properties of Linear Elastin-Derived Short Peptides by Simple Cyclization: Strong Self-Aggregation Properties of Cyclo[FPGVG]n, Consisting Only of Natural Amino Acids

artículo científico publicado en 2018

Evaluation of the Influence of Halogenation on the Binding of Bisphenol A to the Estrogen-Related Receptor γ

artículo científico publicado en 2020

Fine spatial assembly for construction of the phenol-binding pocket to capture bisphenol A in the human nuclear receptor estrogen-related receptor γ.

artículo científico publicado en 2012

Highly potent binding and inverse agonist activity of bisphenol A derivatives for retinoid-related orphan nuclear receptor RORγ.

artículo científico publicado en 2012

Interaction mode of the phe-phenyl group of thrombin receptor-tethered ligand SFLLRNP in receptor activation.

artículo científico publicado en 1998

Radar chart deviation analysis of prion protein amino acid composition defines characteristic structural abnormalities of the N-terminal octa-peptide tandem repeat.

artículo científico publicado en 2008

Receptor-binding affinities of bisphenol A and its next-generation analogs for human nuclear receptors

artículo científico publicado en 2019

Role of individual disulfide bridges in the conformation and activity of spinoxin (α-KTx6.13), a potassium channel toxin from Heterometrus spinifer scorpion venom

artículo científico publicado en 2016

Spare interactions of highly potent [Arg(14),Lys(15)]nociceptin for cooperative induction of ORL1 receptor activation.

artículo científico publicado en 2009

Stepwise mechanism of temperature-dependent coacervation of the elastin-like peptide analog dimer, (C(WPGVG)3)2.

artículo científico publicado en 2018

Structural requirements essential for elastin coacervation: favorable spatial arrangements of valine ridges on the three-dimensional structure of elastin-derived polypeptide (VPGVG)n

scientific article published on 14 September 2011

Structural requirements of nociceptin antagonist Ac-RYYRIK-NH2 for receptor binding.

artículo científico publicado en 2002

Synergistic effect of basic residues at positions 14-15 of nociceptin on binding affinity and receptor activation.

artículo científico publicado en 2008

X-ray crystal structure of a dipeptide-chymotrypsin complex in an inhibitory interaction

artículo científico publicado en 1998

cDNA cloning of the housefly pigment-dispersing factor (PDF) precursor protein and its peptide comparison among the insect circadian neuropeptides.

artículo científico publicado en 2004