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A model of breast cancer heterogeneity reveals vascular mimicry as a driver of metastasis

artículo científico publicado en 2015

CIB1 depletion impairs cell survival and tumor growth in triple-negative breast cancer.

artículo científico publicado en 2015

Characterization of cell lines derived from breast cancers and normal mammary tissues for the study of the intrinsic molecular subtypes.

scientific article published on 27 October 2013

Characterization of twenty-five ovarian tumour cell lines that phenocopy primary tumours

artículo científico publicado en 2015

Characterizing the efficacy of cancer therapeutics in patient-derived xenograft models of metastatic breast cancer

artículo científico publicado en 2018

Contaminating cells alter gene signatures in whole organ versus laser capture microdissected tumors: a comparison of experimental breast cancers and their lymph node metastases.

artículo científico publicado en 2007

Differentiation and loss of malignant character of spontaneous pulmonary metastases in patient-derived breast cancer models.

artículo científico publicado en 2014

Endothelial-like properties of claudin-low breast cancer cells promote tumor vascular permeability and metastasis.

artículo científico publicado en 2013

Estrogen receptor positive breast cancer metastasis: altered hormonal sensitivity and tumor aggressiveness in lymphatic vessels and lymph nodes.

artículo científico publicado en 2006

Expression of Six1 in luminal breast cancers predicts poor prognosis and promotes increases in tumor initiating cells by activation of extracellular signal-regulated kinase and transforming growth factor-beta signaling pathways.

artículo científico publicado en 2012

Genomic analysis identifies unique signatures predictive of brain, lung, and liver relapse.

artículo científico publicado en 2011

Genomic structure and identification of a truncated variant message of the mouse estrogen receptor alpha gene.

artículo científico publicado en 2002

HDAC6 Deacetylates HMGN2 to Regulate Stat5a Activity and Breast Cancer Growth.

artículo científico publicado en 2016

Human breast milk and xenoestrogen exposure: a possible impact on human health.

artículo científico publicado en 2005

Identification of a stable molecular signature in mammary tumor endothelial cells that persists in vitro

artículo científico publicado en 2013

Identification of synergistic drug combinations using breast cancer patient-derived xenografts

artículo científico publicado en 2020

Interactions with fibroblasts are distinct in Basal-like and luminal breast cancers.

artículo científico publicado en 2010

Maintenance of hormone responsiveness in luminal breast cancers by suppression of Notch

artículo científico publicado en 2011

Metformin attenuates transforming growth factor beta (TGF-β) mediated oncogenesis in mesenchymal stem-like/claudin-low triple negative breast cancer.

artículo científico publicado en 2016

Molecular subtype and tumor characteristics of breast cancer metastases as assessed by gene expression significantly influence patient post-relapse survival.

artículo científico publicado en 2014

Phosphatidylinositol 3-kinase pathway activation in breast cancer brain metastases

artículo científico publicado el 1 de enero de 2011

Primary breast tumor-derived cellular models: characterization of tumorigenic, metastatic, and cancer-associated fibroblasts in dissociated tumor (DT) cultures

artículo científico publicado en 2014

Quantitative assessment of breast cancer liver metastasis expansion with patient-derived xenografts

scientific article published on 08 May 2019

Rare steroid receptor-negative basal-like tumorigenic cells in luminal subtype human breast cancer xenografts.

artículo científico publicado en 2008

SIX1 induces lymphangiogenesis and metastasis via upregulation of VEGF-C in mouse models of breast cancer

artículo científico publicado en 2012

Separation of breast cancer and organ microenvironment transcriptomes in metastases

artículo científico publicado en 2019

Sox10 Regulates Stem/Progenitor and Mesenchymal Cell States in Mammary Epithelial Cells

artículo científico publicado en 2015

Spontaneous fusion with, and transformation of mouse stroma by, malignant human breast cancer epithelium.

artículo científico publicado en 2006

Taxonomy of breast cancer based on normal cell phenotype predicts outcome.

scientific article published on 27 January 2014

The Six1 homeoprotein induces human mammary carcinoma cells to undergo epithelial-mesenchymal transition and metastasis in mice through increasing TGF-beta signaling

scientific article published on 24 August 2009

The Six1 oncoprotein downregulates p53 via concomitant regulation of RPL26 and microRNA-27a-3p.

artículo científico publicado en 2015

The role of the C-terminal extension (CTE) of the estrogen receptor alpha and beta DNA binding domain in DNA binding and interaction with HMGB.

artículo científico publicado en 2004

The utility of the "Glowing Head" mouse for breast cancer metastasis research

artículo científico publicado en 2020

Thyroid outcome during long-term gonadotropin-releasing hormone agonist treatments for idiopathic precocious puberty

artículo científico publicado en 2007

Tissue-specific pathways for estrogen regulation of ovarian cancer growth and metastasis

artículo científico publicado en 2010

Transcriptomic changes underlying EGFR inhibitor resistance in human and mouse models of basal-like breast cancer

scientific article published in 2022

Transcriptomic classification of genetically engineered mouse models of breast cancer identifies human subtype counterparts

artículo científico publicado en 2013

Vascular endothelial growth factor C promotes breast cancer progression via a novel antioxidant mechanism that involves regulation of superoxide dismutase 3.

artículo científico publicado en 2014

Vascular endothelial growth factor secreted by activated stroma enhances angiogenesis and hormone-independent growth of estrogen receptor-positive breast cancer

artículo científico publicado en 2010

αB-crystallin Expression in Breast Cancer is Associated with Brain Metastasis

artículo científico publicado en 2015